Perfluorohexane sulfonate induces memory impairment and downregulation of neuroproteins via NMDA receptor-mediated PKC-ERK/AMPK signaling pathway

Suppressing Cdk5 Activity by Luteolin Inhibits MPP+-Induced Apoptotic of Neuroblastoma through Erk/Drp1 and Fak/Akt/GSK3β Pathways

(2021) Ratchaneekorn Reudhabibadh et al.   MOLECULES

Acrylamide and its metabolite induce neurotoxicity via modulation of protein kinase C and AMP-activated protein kinase pathways

(2021) Dahlia Triningsih et al.   TOXICOLOGY IN VITRO

Toxicologic evidence of developmental neurotoxicity of Type II pyrethroids cyfluthrin and alpha-cypermethrin in SH-SY5Y cells

(2020) María-Aránzazu Martínez et al.   FOOD AND CHEMICAL TOXICOLOGY

Evaluation of Developmental Toxicity, Developmental Neurotoxicity, and Tissue Dose in Zebrafish Exposed to GenX and Other PFAS

(2020) Shaza Gaballah et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Regulation of the SIRT1 signaling pathway in NMDA-induced Excitotoxicity

(2020) Xiaorong Yang et al.   TOXICOLOGY LETTERS

NMDA receptor-mediated CaMKII/ERK activation contributes to renal fibrosis

(2020) Jingyi Zhou et al.   BMC Nephrology

AMPA receptors are involved in prefrontal direct current stimulation effects on long-term working memory and GAP-43 expression

(2019) Cleciane Waldetário Martins et al.   BEHAVIOURAL BRAIN RESEARCH

Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes

(2019) Juan He et al.   Frontiers in Physiology

Prenatal plasma concentrations of Perfluoroalkyl and polyfluoroalkyl substances and neuropsychological development in children at four years of age

(2019) Jinbo Niu et al.   Environmental Health

GluN2A-NMDA receptor–mediated sustained Ca2+ influx leads to homocysteine-induced neuronal cell death

(2019) Satya Narayan Deep et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cucurbitacin B induces neurogenesis in PC12 cells and protects memory in APP/PS1 mice

(2019) Jing Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans

(2019) Shreesh Raj Sammi et al.   TOXICOLOGICAL SCIENCES

Developmental exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) selectively decreases brain dopamine levels in Northern leopard frogs

(2019) Rachel M. Foguth et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inactivation of GAP-43 due to the depletion of cellular calcium by the Pb and amyloid peptide induced toxicity: An in vitro approach

(2019) Neelima Ayyalasomayajula et al.   CHEMICO-BIOLOGICAL INTERACTIONS

CaMKII Isoforms in Learning and Memory: Localization and Function

(2018) Gisela Zalcman et al.   Frontiers in Molecular Neuroscience

Memory Erasure Experiments Indicate a Critical Role of CaMKII in Memory Storage

(2017) Tom Rossetti et al.   NEURON

Caffeic Acid Phenethyl Ester (CAPE) Protects PC12 Cells from Cisplatin-Induced Neurotoxicity by Activating the NGF-Signaling Pathway

(2017) Rafaela Scalco Ferreira et al.   NEUROTOXICITY RESEARCH

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease

(2017) Annalisa Nobili et al.   Nature Communications

AMP-activated protein kinase is involved in perfluorohexanesulfonate -induced apoptosis of neuronal cells

(2016) Youn Ju Lee et al.   CHEMOSPHERE

Behavioral difficulties in 7-year old children in relation to developmental exposure to perfluorinated alkyl substances

(2016) Youssef Oulhote et al.   ENVIRONMENT INTERNATIONAL

Environmental Chemicals in an Urban Population of Pregnant Women and Their Newborns from San Francisco

(2016) Rachel Morello-Frosch et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Postnatal exposure to PFOS, but not PBDE 99, disturb dopaminergic gene transcription in the mouse CNS

(2016) Stefan Hallgren et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory

(2016) Joongkyu Park et al.   NEURON

Effects of perfluorooctane sulfonate and its alternatives on long-term potentiation in the hippocampus CA1 region of adult rats in vivo

(2016) Qian Zhang et al.   Toxicology Research

The neuroprotection of cannabidiol against MPP + -induced toxicity in PC12 cells involves trkA receptors, upregulation of axonal and synaptic proteins, neuritogenesis, and might be relevant to Parkinson's disease

(2015) Neife Aparecida Guinaim Santos et al.   TOXICOLOGY IN VITRO

Calcium/calmodulin-dependent kinase II and Alzheimer’s disease

(2015) Anshua Ghosh et al.   Molecular Brain

Developmental exposure to the polybrominated diphenyl ether PBDE 209: Neurobehavioural and neuroprotein analysis in adult male and female mice

(2014) Sonja Buratovic et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

NMDA receptor-mediated ERK 1/2 pathway is involved in PFHxS-induced apoptosis of PC12 cells

(2014) Youn Ju Lee et al.   SCIENCE OF THE TOTAL ENVIRONMENT

PFHxS induces apoptosis of neuronal cells via ERK1/2-mediated pathway

(2013) Youn Ju Lee et al.   CHEMOSPHERE

Melatonin improves neuroplasticity by upregulating the growth-associated protein-43 (GAP-43) and NMDAR postsynaptic density-95 (PSD-95) proteins in cultured neurons exposed to glutamate excitotoxicity and in rats subjected to transient focal cerebral isch

(2013) Wei-Sheng Juan et al.   JOURNAL OF PINEAL RESEARCH

The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

(2013) Georges Mairet-Coello et al.   NEURON

A single neonatal exposure to perfluorohexane sulfonate (PFHxS) affects the levels of important neuroproteins in the developing mouse brain

(2013) Iwa Lee et al.   NEUROTOXICOLOGY

Adult dose-dependent behavioral and cognitive disturbances after a single neonatal PFHxS dose

(2013) Henrik Viberg et al.   TOXICOLOGY

Concentrations of perfluoroalkyl compounds in maternal and umbilical cord sera and birth outcomes in Korea

(2012) Youn Ju Lee et al.   CHEMOSPHERE

Calcium/Calmodulin-dependent Protein Kinase II (CaMKII) Inhibition Induces Neurotoxicity via Dysregulation of Glutamate/Calcium Signaling and Hyperexcitability

(2012) Nicole M. Ashpole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perfluorooctane sulfonate induces apoptosis of cerebellar granule cells via a ROS-dependent protein kinase C signaling pathway

(2012) Hyun-Gyo Lee et al.   NEUROTOXICOLOGY

Effects of Polychlorinated Biphenyls on the Development of Neuronal Cells in Growth Period; Structure-Activity Relationship

(2012) Youngrok Do et al.   Experimental Neurobiology

Serum Perfluorinated Compound Concentration and Attention Deficit/Hyperactivity Disorder in Children 5–18 Years of Age

(2011) Cheryl R. Stein et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Polyfluorinated Compounds: Past, Present, and Future

(2011) Andrew B. Lindstrom et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluorochemical (PFC) Exposure in Children: Associations with Impaired Response Inhibition

(2011) Brooks B. Gump et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins

(2011) Robert C Buck et al.   Integrated Environmental Assessment and Management

Evaluation of potential reproductive and developmental toxicity of potassium perfluorohexanesulfonate in Sprague Dawley rats

(2009) John L. Butenhoff et al.   REPRODUCTIVE TOXICOLOGY

Neonatal Exposure to PFOS and PFOA in Mice Results in Changes in Proteins which are Important for Neuronal Growth and Synaptogenesis in the Developing Brain

(2009) Niclas Johansson et al.   TOXICOLOGICAL SCIENCES

The regulation of AMP-activated protein kinase by upstream kinases

(2008) D Carling et al.   INTERNATIONAL JOURNAL OF OBESITY

Neonatal exposure to decabrominated diphenyl ether (PBDE 209) results in changes in BDNF, CaMKII and GAP-43, biochemical substrates of neuronal survival, growth, and synaptogenesis

(2007) Henrik Viberg et al.   NEUROTOXICOLOGY