Piperlongumine induces ROS mediated apoptosis by transcriptional regulation of SMAD4/P21/P53 genes and synergizes with doxorubicin in osteosarcoma cells
出版年份 2022 全文链接
标题
Piperlongumine induces ROS mediated apoptosis by transcriptional regulation of SMAD4/P21/P53 genes and synergizes with doxorubicin in osteosarcoma cells
作者
关键词
Piperlongumine, Herbal medicine, Natural product, Osteosarcoma, SMAD4, Doxorubicin
出版物
CHEMICO-BIOLOGICAL INTERACTIONS
Volume 354, Issue -, Pages 109832
出版商
Elsevier BV
发表日期
2022-01-25
DOI
10.1016/j.cbi.2022.109832
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Anticancer effects of oleanolic acid on human melanoma cells
- (2021) Joong-Seok Woo et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Natural compounds as potential adjuvants to cancer therapy: preclinical evidence
- (2019) Shian‐Ren Lin et al. BRITISH JOURNAL OF PHARMACOLOGY
- Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3
- (2019) Ji Eun Park et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Inhibition of aldehyde dehydrogenase-1 and p-glycoprotein-mediated multidrug resistance by curcumin and vitamin D3 increases sensitivity to paclitaxel in breast cancer
- (2019) Yasmeen M. Attia et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Natural compounds and combination therapy in colorectal cancer treatment
- (2018) A. Rejhová et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Prognostic significance of NF-κB expression in non-small cell lung cancer: A meta-analysis
- (2018) Lijun Gu et al. PLoS One
- Outcomes in non-metastatic treatment naive extremity osteosarcoma patients treated with a novel non-high dosemethotrexate-based, dose-dense combination chemotherapy regimen ‘OGS-12’
- (2017) Jyoti Bajpai et al. EUROPEAN JOURNAL OF CANCER
- Smad4 re-expression increases the sensitivity to parthenolide in colorectal cancer
- (2017) Xuemei Li et al. ONCOLOGY REPORTS
- NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway
- (2017) Arundhati Jana et al. Oncotarget
- Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer
- (2016) Peng Zou et al. CANCER LETTERS
- Bioactive natural products in cancer prevention and therapy: Progress and promise
- (2016) Anupam Bishayee et al. SEMINARS IN CANCER BIOLOGY
- miR-574-3p acts as a tumor promoter in osteosarcoma by targeting SMAD4 signaling pathway
- (2016) Haidong Xu et al. Oncology Letters
- Prognostic value of tumor suppressors in osteosarcoma before and after neoadjuvant chemotherapy
- (2015) Bernhard Robl et al. BMC CANCER
- Piperlongumine Suppresses Growth and Sensitizes Pancreatic Tumors to Gemcitabine in a Xenograft Mouse Model by Modulating the NF-kappa B Pathway
- (2015) Y. Wang et al. Cancer Prevention Research
- Loss of SMAD4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL15-CCR1 Chemokine Axis
- (2015) S. Inamoto et al. CLINICAL CANCER RESEARCH
- SMAD4 gene promoter mutations in patients with thyroid tumors
- (2015) Aleksandra Nikolic et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Osteosarcoma: Current Treatment and a Collaborative Pathway to Success
- (2015) Michael S. Isakoff et al. JOURNAL OF CLINICAL ONCOLOGY
- Piperlongumine for Enhancing Oral Bioavailability and Cytotoxicity of Docetaxel in Triple-Negative Breast Cancer
- (2015) Ketan Patel et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Review of microRNA in osteosarcoma and chondrosarcoma
- (2015) Le Chang et al. MEDICAL ONCOLOGY
- Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP
- (2015) Yong Chen et al. Oncotarget
- Piperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer
- (2015) Jong-Lyel Roh et al. Oncotarget
- Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells
- (2014) Shweta Shrivastava et al. APOPTOSIS
- SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells
- (2014) Yu-Wen Chen et al. BMC CANCER
- Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway
- (2014) B Zhang et al. BRITISH JOURNAL OF CANCER
- Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death
- (2014) P Makhov et al. BRITISH JOURNAL OF CANCER
- Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer
- (2014) U Bharadwaj et al. ONCOGENE
- Piperlongumine Induces Apoptosis and Synergizes with Cisplatin or Paclitaxel in Human Ovarian Cancer Cells
- (2014) Li-Hua Gong et al. Oxidative Medicine and Cellular Longevity
- Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation
- (2014) Lijuan Sun et al. Food & Function
- Piperlongumine selectively kills glioblastoma multiforme cells via reactive oxygen species accumulation dependent JNK and p38 activation
- (2013) Ju Mei Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ursolic acid inhibits tumor angiogenesis and induces apoptosis through mitochondrial-dependent pathway in Ehrlich ascites carcinoma tumor
- (2013) Sarita Saraswati et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Piperlongumine inhibits NF-κB activity and attenuates aggressive growth characteristics of prostate cancer cells
- (2013) Serge Ginzburg et al. PROSTATE
- Activation of ERK signaling and induction of colon cancer cell death by piperlongumine
- (2013) H. Randhawa et al. TOXICOLOGY IN VITRO
- Gui-ling-gao, a traditional Chinese functional food, prevents oxidative stress-induced apoptosis in H9c2 cardiomyocytes
- (2013) Fan Li et al. Food & Function
- Overview of the therapeutic potential of piplartine (piperlongumine)
- (2012) Daniel P. Bezerra et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Smad4 Inactivation Promotes Malignancy and Drug Resistance of Colon Cancer
- (2011) P. Papageorgis et al. CANCER RESEARCH
- Anti-tumor effects of dihydroartemisinin on human osteosarcoma
- (2011) Ye Ji et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Role of Bcl-2 family proteins and caspases in the regulation of apoptosis
- (2011) Mohammad Shamsul Ola et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion
- (2010) Y Wu et al. BRITISH JOURNAL OF CANCER
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons
- (2009) Lisa Mirabello et al. INTERNATIONAL JOURNAL OF CANCER
- Survivin: Key Regulator of Mitosis and Apoptosis and Novel Target for Cancer Therapeutics
- (2008) A. C. Mita et al. CLINICAL CANCER RESEARCH
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started