Robust, scalable construction of an electrophilic deuterated methylthiolating reagent: facile access to SCD3-containing scaffolds
出版年份 2022 全文链接
标题
Robust, scalable construction of an electrophilic deuterated methylthiolating reagent: facile access to SCD3-containing scaffolds
作者
关键词
-
出版物
CHEMICAL COMMUNICATIONS
Volume -, Issue -, Pages -
出版商
Royal Society of Chemistry (RSC)
发表日期
2022-01-26
DOI
10.1039/d1cc07184j
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Desulfonylation via Radical Process: Recent Developments in Organic Synthesis
- (2021) Xue-Qiang Chu et al. CHEMICAL REVIEWS
- Transition-Metal-Free Reductive Cross-Coupling Employing Metabisulfite as a Connector: General Construction of Alkyl–Alkyl Sulfones
- (2021) Yingying Meng et al. CCS Chemistry
- Bioinspired design of a robust d3-methylating agent
- (2020) Minyan Wang et al. Science Advances
- Recent Advances in Asymmetric Organomulticatalysis
- (2020) Xiao Xiao et al. ADVANCED SYNTHESIS & CATALYSIS
- Copper(I)‐Catalyzed Asymmetric Interrupted Kinugasa Reaction: Synthesis of α‐Thiofunctional Chiral β‐Lactams
- (2020) Jialin Qi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Applications of deuterium in medicinal chemistry
- (2019) Tracey Pirali et al. JOURNAL OF MEDICINAL CHEMISTRY
- Trideuteromethylation Enabled by a Sulfoxonium Metathesis Reaction
- (2019) Zuyuan Shen et al. ORGANIC LETTERS
- Reduction of CO2 with NaBH4/I2 for the Conversion of Thiophenols to Aryl Methyl Sulfides
- (2019) Bo Zhang et al. JOURNAL OF ORGANIC CHEMISTRY
- Design and application of α-ketothioesters as 1,2-dicarbonyl-forming reagents
- (2019) Ming Wang et al. Nature Communications
- Multicomponent Reductive Cross-Coupling of an Inorganic Sulfur Dioxide Surrogate: Straightforward Construction of Diversely Functionalized Sulfones
- (2019) Yingying Meng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of Difluoromethylthioesters from Aldehydes
- (2018) Shi-Huan Guo et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences
- (2018) Jens Atzrodt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- C−H Functionalisation for Hydrogen Isotope Exchange
- (2018) Jens Atzrodt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Nickel and Nucleophilic Cobalt-Catalyzed Trideuteriomethylation of Aryl Halides Using Trideuteriomethyl p-Toluenesulfonate
- (2018) Kimihiro Komeyama et al. ORGANIC LETTERS
- Radical difluoromethylthiolation of aromatics enabled by visible light
- (2018) Jianbin Li et al. Chemical Science
- Polysulfurating reagent design for unsymmetrical polysulfide construction
- (2018) Xiao Xiao et al. Nature Communications
- Nickel-catalyzed reductive thiolation and selenylation of unactivated alkyl bromides
- (2018) Yi Fang et al. Nature Communications
- Highly mono-selective ortho-methylthiolation of benzamides via cobalt-catalyzed sp2 C–H activation
- (2018) Liang Hu et al. Organic Chemistry Frontiers
- Chemical and structural effects of base modifications in messenger RNA
- (2017) Emily M. Harcourt et al. NATURE
- First deuterated drug approved
- (2017) Charles Schmidt NATURE BIOTECHNOLOGY
- Recent developments in sulfur–carbon bond formation reaction involving thiosulfates
- (2017) Zongjun Qiao et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- PhSO2SCF2H: A Shelf-Stable, Easily Scalable Reagent for Radical Difluoromethylthiolation
- (2016) Dianhu Zhu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- New Design of a Disulfurating Reagent: Facile and Straightforward Pathway to Unsymmetrical Disulfanes by Copper-Catalyzed Oxidative Cross-Coupling
- (2016) Xiao Xiao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Visible light catalyzed methylsulfoxidation of (het)aryl diazonium salts using DMSO
- (2016) Mukund M. D. Pramanik et al. CHEMICAL COMMUNICATIONS
- Pesticide Chemical Research in Toxicology: Lessons from Nature
- (2016) John E. Casida et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Unexpected Metabolic Reactions and Secondary Targets of Pesticide Action
- (2016) John E. Casida JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- The Importance of Being Me: Magic Methyls, Methyltransferase Inhibitors, and the Discovery of Tazemetostat
- (2016) Kevin W. Kuntz et al. JOURNAL OF MEDICINAL CHEMISTRY
- Thioridazine Alters the Cell-Envelope Permeability of Mycobacterium tuberculosis
- (2016) Jeroen de Keijzer et al. JOURNAL OF PROTEOME RESEARCH
- Deuterated drugs draw heavier backing
- (2016) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Sulfur atom transfer (SAT) reaction
- (2016) Xuefeng Jiang PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
- Isotope chemistry; a useful tool in the drug discovery arsenal
- (2015) Charles S. Elmore et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Transition-metal-free persulfuration to construct unsymmetrical disulfides and mechanistic study of the sulfur redox process
- (2015) Xiao Xiao et al. CHEMICAL COMMUNICATIONS
- Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions
- (2014) Xiu-Hua Xu et al. CHEMICAL REVIEWS
- Beyond C, H, O, and N! Analysis of the Elemental Composition of U.S. FDA Approved Drug Architectures
- (2014) Brandon R. Smith et al. JOURNAL OF MEDICINAL CHEMISTRY
- Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions
- (2013) Heike Schönherr et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Using Deuterium in Drug Discovery: Leaving the Label in the Drug
- (2013) Thomas G. Gant JOURNAL OF MEDICINAL CHEMISTRY
- Data-Mining for Sulfur and Fluorine: An Evaluation of Pharmaceuticals To Reveal Opportunities for Drug Design and Discovery
- (2013) Elizabeth A. Ilardi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Efficient Access to 1,4-Benzothiazine: Palladium-Catalyzed Double C–S Bond Formation Using Na2S2O3 as Sulfurating Reagent
- (2013) Zongjun Qiao et al. ORGANIC LETTERS
- Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents
- (2013) Yaoqiu Zhu et al. ACS Medicinal Chemistry Letters
- Control of Oxidative Posttranslational Cysteine Modifications: From Intricate Chemistry to Widespread Biological and Medical Applications
- (2011) Claus Jacob et al. CHEMICAL RESEARCH IN TOXICOLOGY
- The Methylation Effect in Medicinal Chemistry
- (2011) Eliezer J. Barreiro et al. CHEMICAL REVIEWS
- Identification, Characterization, and Implications of Species-Dependent Plasma Protein Binding for the Oral Hedgehog Pathway Inhibitor Vismodegib (GDC-0449)
- (2011) Anthony M. Giannetti et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation
- (2011) Li Zhang et al. NATURE
- Metal-catalysed isotopic exchange labelling: 30 years of experience in pharmaceutical R&D
- (2010) Paul H. Allen et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- A pictorial representation of zero-point energy and tunnelling contributions to primary hydrogen isotope effects
- (2010) R. A. More O'Ferrall JOURNAL OF PHYSICAL ORGANIC CHEMISTRY
- Stability of ricobendazole in aqueous solutions
- (2009) Zimei Wu et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- The 'wired' universe of organic chemistry
- (2009) Bartosz A. Grzybowski et al. Nature Chemistry
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More