Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A
出版年份 2021 全文链接
标题
Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A
作者
关键词
breast cancer, combination therapy, epigenetic therapy, UNC0638, CI-994 (tacedinaline)
出版物
BIOMEDICINE & PHARMACOTHERAPY
Volume 145, Issue -, Pages 112431
出版商
Elsevier BV
发表日期
2021-11-16
DOI
10.1016/j.biopha.2021.112431
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inhibition of histone methyltransferase G9a attenuates liver cancer initiation by sensitizing DNA-damaged hepatocytes to p53-induced apoptosis
- (2021) Takuma Nakatsuka et al. Cell Death & Disease
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Epigenetic mechanisms in breast cancer therapy and resistance
- (2021) Liliana Garcia-Martinez et al. Nature Communications
- Pancancer survival analysis of cancer hallmark genes
- (2021) Ádám Nagy et al. Scientific Reports
- Advances in epigenetic therapeutics with focus on solid tumors
- (2021) Ning Jin et al. Clinical Epigenetics
- Prognostic Significance of BIRC5/Survivin in Breast Cancer: Results from Three Independent Cohorts
- (2021) Nina Oparina et al. Cancers
- Interplay between BRCA1 and GADD45A and Its Potential for Nucleotide Excision Repair in Breast Cancer Pathogenesis
- (2020) Sylwia Pietrasik et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Overcoming Endocrine Resistance in Breast Cancer
- (2020) Ariella B. Hanker et al. CANCER CELL
- Visualizing and interpreting cancer genomics data via the Xena platform
- (2020) Mary J. Goldman et al. NATURE BIOTECHNOLOGY
- Downregulation of the DNA Repair Gene DDB2 by Arecoline Is through p53’s DNA-Binding Domain and Is Correlated with Poor Outcome of Head and Neck Cancer Patients with Betel Quid Consumption
- (2020) Yu-Chu Wang et al. Cancers
- Triple‑negative breast cancer therapy: Current and future perspectives (Review)
- (2020) Kwang‑Ai Won et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Triggering a switch from basal- to luminal-like breast cancer subtype by the small-molecule diptoindonesin G via induction of GABARAPL1
- (2020) Minmin Fan et al. Cell Death & Disease
- FZD5 contributes to TNBC proliferation, DNA damage repair and stemness
- (2020) Yu Sun et al. Cell Death & Disease
- Cell Reprogramming in Tumorigenesis and Its Therapeutic Implications for Breast Cancer
- (2019) Pei-Yi Chu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Combining epigenetic drugs with other therapies for solid tumours — past lessons and future promise
- (2019) Daphné Morel et al. Nature Reviews Clinical Oncology
- GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer
- (2019) Na Han et al. OncoTargets and Therapy
- Inhibition of Survivin by Adenovirus Vector Enhanced Paclitaxel-induced Apoptosis in Breast Cancer Cells
- (2018) TOSHIHIRO TANAKA et al. ANTICANCER RESEARCH
- EHMT2 is a metastasis regulator in breast cancer
- (2018) Kwangho Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- GSCALite: a web server for gene set cancer analysis
- (2018) Chun-Jie Liu et al. BIOINFORMATICS
- Trace of survivin in cancer
- (2018) Fereshteh Shojaei et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-de
- (2018) So Young Kim et al. MOLECULAR CARCINOGENESIS
- Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling
- (2018) Pernilla Roswall et al. NATURE MEDICINE
- MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state
- (2018) Vittoria Poli et al. Nature Communications
- Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic–Mediating Machinery
- (2018) Yifeng Gao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Novel Clofarabine-Based Combinations with Polyphenols Epigenetically Reactivate Retinoic Acid Receptor Beta, Inhibit Cell Growth, and Induce Apoptosis of Breast Cancer Cells
- (2018) Katarzyna Lubecka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer
- (2018) Keqiang Zhang et al. Molecular Cancer
- A subcellular map of the human proteome
- (2017) Peter J. Thul et al. SCIENCE
- A pathology atlas of the human cancer transcriptome
- (2017) Mathias Uhlen et al. SCIENCE
- UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses
- (2017) Darshan S. Chandrashekar et al. NEOPLASIA
- Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs
- (2016) Gerard L. Brien et al. CANCER CELL
- G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status
- (2016) Pallavi Agarwal et al. CANCER LETTERS
- Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth
- (2016) R. Pathania et al. CANCER RESEARCH
- Terminal differentiation induction as DNA damage response in hematopoietic stem cells by GADD45A
- (2016) Susanne Wingert et al. EXPERIMENTAL HEMATOLOGY
- HDAC2 overexpression is a poor prognostic factor of breast cancer patients with increased multidrug resistance-associated protein expression who received anthracyclines therapy
- (2016) Haishan Zhao et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
- DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival
- (2016) Susanne Wingert et al. STEM CELLS
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- A pan-cancer proteomic perspective on The Cancer Genome Atlas
- (2014) Rehan Akbani et al. Nature Communications
- Autophagy and reactive oxygen species modulate cytotoxicity induced by suppression of ATM kinase activity in head and neck cancer cells
- (2012) Chang-Shen Lin et al. ORAL ONCOLOGY
- Molecular biology in breast cancer: Intrinsic subtypes and signaling pathways
- (2011) Pilar Eroles et al. CANCER TREATMENT REVIEWS
- VPA inhibits breast cancer cell migration by specifically targeting HDAC2 and down-regulating Survivin
- (2011) Lei Zhang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
- (2011) Masoud Vedadi et al. Nature Chemical Biology
- Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non-Small Cell Lung Cancer
- (2011) R. A. Juergens et al. Cancer Discovery
- Lower ataxia telangiectasia mutated (ATM) mRNA expression is correlated with poor outcome of laryngeal and pharyngeal cancer patients
- (2010) K.-W. Lee et al. ANNALS OF ONCOLOGY
- Arecoline, a major alkaloid of areca nut, inhibits p53, represses DNA repair, and triggers DNA damage response in human epithelial cells
- (2008) Yi-Shan Tsai et al. TOXICOLOGY
- Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts
- (2007) Lalji K. Gediya et al. BIOORGANIC & MEDICINAL CHEMISTRY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started