Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer

G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin

(2017) Ya-fang Wang et al.   Nature Communications

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium

(2016) C S Daly et al.   ONCOGENE

Functional Role of G9a Histone Methyltransferase in Cancer

(2015) Francesco Casciello et al.   Frontiers in Immunology

Enhanced Expression of EHMT2 Is Involved in the Proliferation of Cancer Cells through Negative Regulation of SIAH1

(2015) Hyun-Soo Cho et al.   NEOPLASIA

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Frequent Overexpression ofHMGA2in Human Atypical Teratoid/Rhabdoid Tumor and Its Correlation withlet-7a3/let-7bmiRNA

(2014) Keqiang Zhang et al.   CLINICAL CANCER RESEARCH

The methyltransferase G9a regulates HoxA9-dependent transcription in AML

(2014) B. Lehnertz et al.   GENES & DEVELOPMENT

SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway

(2014) Qiao-Yang Sun et al.   JOURNAL OF PATHOLOGY

The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis

(2014) Kuo-Tai Hua et al.   Molecular Cancer

Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma

(2014) Kai-Chun Li et al.   Molecular Cancer

Wnt inhibitory factor 1 suppresses cancer stemness and induces cellular senescence

(2014) I Ramachandran et al.   Cell Death & Disease

Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors

(2013) Ji Tae Kim et al.   CARCINOGENESIS

The Histone H3 Methyltransferase G9A Epigenetically Activates the Serine-Glycine Synthesis Pathway to Sustain Cancer Cell Survival and Proliferation

(2013) Jane Ding et al.   Cell Metabolism

Wnt Signaling Pathway in Non-Small Cell Lung Cancer

(2013) D. J. Stewart   JNCI-Journal of the National Cancer Institute

Epigenetic mechanisms in tumorigenesis, tumor cell heterogeneity and drug resistance

(2012) Roel H. Wilting et al.   DRUG RESISTANCE UPDATES

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

(2012) Chenfang Dong et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

(2012) Joshua C. Black et al.   MOLECULAR CELL

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

(2011) Masoud Vedadi et al.   Nature Chemical Biology

Hypoxia-induced methylation of a pontin chromatin remodeling factor

(2011) J. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H3K9 Histone Methyltransferase G9a Promotes Lung Cancer Invasion and Metastasis by Silencing the Cell Adhesion Molecule Ep-CAM

(2010) M.-W. Chen et al.   CANCER RESEARCH

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53

(2010) Jing Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers

(2009) Mathewos Tessema et al.   CARCINOGENESIS

Heterochromatin protein 1α: a hallmark of cell proliferation relevant to clinical oncology

(2009) Leanne De Koning et al.   EMBO Molecular Medicine