Dual targeted delivery of statins and nucleic acids by chitosan-based nanoparticles for enhanced antiatherosclerotic efficacy

Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

(2020) Cheng Gao et al.   Nature Communications

Introduction to the review series on atherosclerotic calcification

(2020) Gian Paolo Fadini et al.   ATHEROSCLEROSIS

Advances in oligonucleotide drug delivery

(2020) Thomas C. Roberts et al.   NATURE REVIEWS DRUG DISCOVERY

Site‐Specific MicroRNA‐33 Antagonism by pH‐Responsive Nanotherapies for Treatment of Atherosclerosis via Regulating Cholesterol Efflux and Adaptive Immunity

(2020) Chenwen Li et al.   ADVANCED FUNCTIONAL MATERIALS

New Approaches for the Prevention and Treatment of Cardiovascular Disease: Focus on Lipoproteins and Inflammation

(2020) Aliza Hussain et al.   Annual Review of Medicine

The current state and future directions of RNAi-based therapeutics

(2019) Ryan L. Setten et al.   NATURE REVIEWS DRUG DISCOVERY

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

Delivery of microRNAs by Chitosan Nanoparticles to Functionally Alter Macrophage Cholesterol Efflux In Vitro and In Vivo

(2019) My-Anh Nguyen et al.   ACS Nano

The C‐type lectin receptor MGL senses N ‐acetylgalactosamine on the unique Staphylococcus aureus ST395 wall teichoic acid

(2019) Malgorzata E. Mnich et al.   CELLULAR MICROBIOLOGY

Atherosclerosis

(2019) Peter Libby et al.   Nature Reviews Disease Primers

Targeted delivery of anti-inflammatory cytokine by nanocarrier reduces atherosclerosis in Apo E−/- mice

(2019) Manse Kim et al.   BIOMATERIALS

The role of mucus on drug transport and its potential to affect therapeutic outcomes

(2018) Xabier Murgia et al.   ADVANCED DRUG DELIVERY REVIEWS

Metabolic Induction of Trained Immunity through the Mevalonate Pathway

(2018) Siroon Bekkering et al.   CELL

LDL and foam cell formation as the basis of atherogenesis

(2018) Alexander N. Orekhov   CURRENT OPINION IN LIPIDOLOGY

Monocyte-to-HDL-cholesterol ratio as a prognostic marker in cardiovascular diseases

(2018) Shiva Ganjali et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TNFα gene silencing mediated by orally targeted nanoparticles combined with interleukin-22 for synergistic combination therapy of ulcerative colitis

(2018) Bo Xiao et al.   JOURNAL OF CONTROLLED RELEASE

Platelet membrane-coated nanoparticle-mediated targeting delivery of Rapamycin blocks atherosclerotic plaque development and stabilizes plaque in apolipoprotein E-deficient (ApoE−/−) mice

(2018) Yanan Song et al.   Nanomedicine-Nanotechnology Biology and Medicine

Alnylam launches era of RNAi drugs

(2018) Ken Garber   NATURE BIOTECHNOLOGY

Application of nanotechnology to improve the therapeutic benefits of statins

(2018) Shahla Korani et al.   DRUG DISCOVERY TODAY

Clinician’s Guide to Reducing Inflammation to Reduce Atherothrombotic Risk

(2018) Paul M Ridker   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Food, gastrointestinal pH, and models of oral drug absorption

(2017) Ahmad Y. Abuhelwa et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Physicochemical properties of mucus and their impact on transmucosal drug delivery

(2017) Jasmim Leal et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effect of Statin Treatment on Modifying Plaque Composition

(2016) Seung-Jung Park et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

In vitro and ex vivo strategies for intracellular delivery

(2016) Martin P. Stewart et al.   NATURE

Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism

(2016) Ping Zhang et al.   Nutrition & Metabolism

The use of polymer-based nanoparticles and nanostructured materials in treatment and diagnosis of cardiovascular diseases: Recent advances and emerging designs

(2016) Yen-Jen Wang et al.   PROGRESS IN POLYMER SCIENCE

A review on the strategies for oral delivery of proteins and peptides and their clinical perspectives

(2016) Abdul Muheem et al.   SAUDI PHARMACEUTICAL JOURNAL

Atherosclerotic Plaque Targeting Mechanism of Long-Circulating Nanoparticles Established by Multimodal Imaging

(2015) Mark E. Lobatto et al.   ACS Nano

MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

(2015) Mireille Ouimet et al.   JOURNAL OF CLINICAL INVESTIGATION

Asialoglycoprotein receptor mediated hepatocyte targeting — Strategies and applications

(2015) Anisha A. D'Souza et al.   JOURNAL OF CONTROLLED RELEASE

A Diet-Sensitive BAF60a-Mediated Pathway Links Hepatic Bile Acid Metabolism to Cholesterol Absorption and Atherosclerosis

(2015) Zhuo-Xian Meng et al.   Cell Reports

Oral delivery of shRNA and siRNA via multifunctional polymeric nanoparticles for synergistic cancer therapy

(2014) Lu Han et al.   BIOMATERIALS

A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation

(2014) Raphaël Duivenvoorden et al.   Nature Communications

Multifunctional polymeric nanoparticles for oral delivery of TNF-α siRNA to macrophages

(2013) Chunbai He et al.   BIOMATERIALS

Statin Therapy for Primary Prevention of Cardiovascular Disease

(2013) Fiona C. Taylor et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MicroRNA‐33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE −/− Mice

(2013) Takahiro Horie et al.   Journal of the American Heart Association

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

(2011) Katey J. Rayner et al.   JOURNAL OF CLINICAL INVESTIGATION

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect

(2010) Sarbari Acharya et al.   ADVANCED DRUG DELIVERY REVIEWS

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE