Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology

Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness

(2021) Weiqiu Cheng et al.   JAMA Psychiatry

Genetic correlations between subcortical brain volumes and psychiatric disorders

(2020) Kazutaka Ohi et al.   BRITISH JOURNAL OF PSYCHIATRY

Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model

(2020) Dominic Holland et al.   PLoS Genetics

The polygenic architecture of schizophrenia — rethinking pathogenesis and nosology

(2020) Olav B. Smeland et al.   Nature Reviews Neurology

Understanding the genetic determinants of the brain with MOSTest

(2020) Dennis van der Meer et al.   Nature Communications

Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk

(2019) Dag Alnæs et al.   JAMA Psychiatry

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

(2019) Oleksandr Frei et al.   Nature Communications

PRSice-2: Polygenic Risk Score software for biobank-scale data

(2019) Shing Wan Choi et al.   GigaScience

Discovery of shared genomic loci using the conditional false discovery rate approach

(2019) Olav B. Smeland et al.   HUMAN GENETICS

A global overview of pleiotropy and genetic architecture in complex traits

(2019) Kyoko Watanabe et al.   NATURE GENETICS

Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms

(2019) Rebecca L. Walker et al.   CELL

Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium

(2018) Theo G.M. van Erp et al.   BIOLOGICAL PSYCHIATRY

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

(2018) Alexander Gusev et al.   NATURE GENETICS

Convergence of placenta biology and genetic risk for schizophrenia

(2018) Gianluca Ursini et al.   NATURE MEDICINE

Quantitative assessment of structural image quality

(2018) Adon F.G. Rosen et al.   NEUROIMAGE

Genomic screening in rare disorders: New mutations and phenotypes, highlighting ALG14 as a novel cause of severe intellectual disability

(2018) Malin Kvarnung et al.   CLINICAL GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models

(2018) Thomas Wolfers et al.   JAMA Psychiatry

Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls

(2017) T Moberget et al.   MOLECULAR PSYCHIATRY

Early and lethal neurodegeneration with myasthenic and myopathic features

(2017) David C. Schorling et al.   NEUROLOGY

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription

(2016) Cristina Dias et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Familial Risk and Heritability of Cancer Among Twins in Nordic Countries

(2016) Lorelei A. Mucci et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

(2016) Barbara Franke et al.   NATURE NEUROSCIENCE

Multimodal population brain imaging in the UK Biobank prospective epidemiological study

(2016) Karla L Miller et al.   NATURE NEUROSCIENCE

Clinical Diagnosis of Mental Disorders Immediately Before and After Cancer Diagnosis

(2016) Donghao Lu et al.   JAMA Oncology

Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium

(2015) T G M van Erp et al.   MOLECULAR PSYCHIATRY

Disintegration of Sensorimotor Brain Networks in Schizophrenia

(2015) Tobias Kaufmann et al.   SCHIZOPHRENIA BULLETIN

Cognitive Effort and Schizophrenia Modulate Large-Scale Functional Brain Connectivity

(2015) Christine Lycke Brandt et al.   SCHIZOPHRENIA BULLETIN

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

REV-ERB and ROR nuclear receptors as drug targets

(2014) Douglas J. Kojetin et al.   NATURE REVIEWS DRUG DISCOVERY

Boosting the Power of Schizophrenia Genetics by Leveraging New Statistical Tools

(2013) O. A. Andreassen et al.   SCHIZOPHRENIA BULLETIN

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rank-Based Inverse Normal Transformations are Increasingly Used, But are They Merited?

(2009) T. Mark Beasley et al.   BEHAVIOR GENETICS

Bcl11A/CTIP1 regulates expression of DCC and MAP1b in control of axon branching and dendrite outgrowth

(2009) Ting-Yu Kuo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE