标题
Discovery of shared genomic loci using the conditional false discovery rate approach
作者
关键词
-
出版物
HUMAN GENETICS
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-14
DOI
10.1007/s00439-019-02060-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
- (2019) Olav B Smeland et al. MOLECULAR PSYCHIATRY
- Concordance of genetic variation that increases risk for tourette syndrome and that influences its underlying neurocircuitry
- (2019) Mary Mufford et al. Translational Psychiatry
- Genome-wide association study identifies 30 loci associated with bipolar disorder
- (2019) Eli A. Stahl et al. NATURE GENETICS
- Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes
- (2019) Ole Kristian Drange et al. Frontiers in Neuroscience
- Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
- (2019) Oleksandr Frei et al. Nature Communications
- Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits
- (2019) Andrew D. Grotzinger et al. Nature Human Behaviour
- Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment
- (2018) Alexey A. Shadrin et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
- Psychiatric genetics and the structure of psychopathology
- (2018) Jordan W. Smoller et al. MOLECULAR PSYCHIATRY
- Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
- (2018) Jeanne E. Savage et al. NATURE GENETICS
- Multi-trait analysis of genome-wide association summary statistics using MTAG
- (2018) Patrick Turley et al. NATURE GENETICS
- Analysis of shared heritability in common disorders of the brain
- (2018) et al. SCIENCE
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
- (2018) Gail Davies et al. Nature Communications
- Causal associations between risk factors and common diseases inferred from GWAS summary data
- (2018) Zhihong Zhu et al. Nature Communications
- Identification of shared genetic variants between schizophrenia and lung cancer
- (2018) Verena Zuber et al. Scientific Reports
- Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
- (2018) Iris Broce et al. PLOS MEDICINE
- Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum
- (2018) Celeste M. Karch et al. JAMA Neurology
- Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease
- (2018) Iris J. Broce et al. ACTA NEUROPATHOLOGICA
- Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
- (2018) Dennis van der Meer et al. MOLECULAR PSYCHIATRY
- Modeling prior information of common genetic variants improves gene discovery for neuroticism
- (2017) Min-Tzu Lo et al. HUMAN MOLECULAR GENETICS
- Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method
- (2017) Yuan Hu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Novel common variants associated with body mass index and coronary artery disease detected using a pleiotropic cFDR method
- (2017) Wan-Qiang Lv et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
- (2017) Suzanne Sniekers et al. NATURE GENETICS
- Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants
- (2017) Bendik S. Winsvold et al. PLoS One
- Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms
- (2017) Olav B Smeland et al. SCHIZOPHRENIA BULLETIN
- Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
- (2017) Russell L. McLaughlin et al. Nature Communications
- Statistical methods to detect pleiotropy in human complex traits
- (2017) Sophie Hackinger et al. Open Biology
- Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function
- (2017) Olav B. Smeland et al. JAMA Psychiatry
- Identification of genetic loci shared between schizophrenia and the Big Five personality traits
- (2017) Olav B. Smeland et al. Scientific Reports
- Age-Dependent Pleiotropy Between General Cognitive Function and Major Psychiatric Disorders
- (2016) W. David Hill et al. BIOLOGICAL PSYCHIATRY
- New statistical approaches exploit the polygenic architecture of schizophrenia—implications for the underlying neurobiology
- (2016) Andrew J Schork et al. CURRENT OPINION IN NEUROBIOLOGY
- A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping
- (2016) Buhm Han et al. HUMAN MOLECULAR GENETICS
- Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
- (2016) Raffaele Ferrari et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors
- (2016) Yunpeng Wang et al. Multiple Sclerosis Journal
- Detection and interpretation of shared genetic influences on 42 human traits
- (2016) Joseph K Pickrell et al. NATURE GENETICS
- Dissecting the genetics of complex traits using summary association statistics
- (2016) Bogdan Pasaniuc et al. NATURE REVIEWS GENETICS
- Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
- (2016) Stéphanie Le Hellard et al. SCHIZOPHRENIA BULLETIN
- Genetic pleiotropy in complex traits and diseases: implications for genomic medicine
- (2016) Jacob Gratten et al. Genome Medicine
- Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS
- (2016) Yunpeng Wang et al. PLoS Genetics
- Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
- (2016) Jennifer S. Yokoyama et al. JAMA Neurology
- Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors
- (2016) Yunpeng Wang et al. Multiple Sclerosis Journal
- Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms
- (2015) Hansjörg Baurecht et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease
- (2015) R. S. Desikan et al. CIRCULATION
- Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsNovelty and Significance
- (2015) Marissa LeBlanc et al. CIRCULATION RESEARCH
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- A Pleiotropy-Informed Bayesian False Discovery Rate Adapted to a Shared Control Design Finds New Disease Associations From GWAS Summary Statistics
- (2015) James Liley et al. PLoS Genetics
- Identifying Common Genetic Variants in Blood Pressure Due to Polygenic Pleiotropy With Associated Phenotypes
- (2014) Ole A. Andreassen et al. HYPERTENSION
- Shared common variants in prostate cancer and blood lipids
- (2014) Ole A Andreassen et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
- (2014) O A Andreassen et al. MOLECULAR PSYCHIATRY
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors
- (2013) Ole A. Andreassen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)
- (2013) T Lencz et al. MOLECULAR PSYCHIATRY
- Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
- (2013) Jimmy Z Liu et al. NATURE GENETICS
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
- (2013) S Hong Lee et al. NATURE GENETICS
- Pleiotropy in complex traits: challenges and strategies
- (2013) Nadia Solovieff et al. NATURE REVIEWS GENETICS
- Boosting the Power of Schizophrenia Genetics by Leveraging New Statistical Tools
- (2013) O. A. Andreassen et al. SCHIZOPHRENIA BULLETIN
- TATES: Efficient Multivariate Genotype-Phenotype Analysis for Genome-Wide Association Studies
- (2013) Sophie van der Sluis et al. PLoS Genetics
- All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs
- (2013) Andrew J. Schork et al. PLoS Genetics
- Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
- (2013) Ole A. Andreassen et al. PLoS Genetics
- Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci
- (2012) David Ellinghaus et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Subset-Based Approach Improves Power and Interpretation for the Combined Analysis of Genetic Association Studies of Heterogeneous Traits
- (2012) Samsiddhi Bhattacharjee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood
- (2012) S.H. Lee et al. BIOINFORMATICS
- MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS
- (2012) Paul F. O’Reilly et al. PLoS One
- Abundant Pleiotropy in Human Complex Diseases and Traits
- (2011) Shanya Sivakumaran et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The effect of correlation in false discovery rate estimation
- (2011) A. Schwartzman et al. BIOMETRIKA
- Transethnic meta-analysis of genomewide association studies
- (2011) Andrew P. Morris GENETIC EPIDEMIOLOGY
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- Meta-Analysis of Genome-wide Association Studies with Overlapping Subjects
- (2009) Dan-Yu Lin et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Finding the missing heritability of complex diseases
- (2009) Teri A. Manolio et al. NATURE
- Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
- (2009) Shaun M. Purcell et al. NATURE
- Long-Range LD Can Confound Genome Scans in Admixed Populations
- (2008) Alkes L. Price et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
- (2007) Debbie A. Lawlor et al. STATISTICS IN MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started