Imatinib-induced hepatotoxicity via oxidative stress and activation of NLRP3 inflammasome: an in vitro and in vivo study
出版年份 2022 全文链接
标题
Imatinib-induced hepatotoxicity via oxidative stress and activation of NLRP3 inflammasome: an in vitro and in vivo study
作者
关键词
-
出版物
ARCHIVES OF TOXICOLOGY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-02-22
DOI
10.1007/s00204-022-03245-x
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis
- (2020) Kun Wang et al. CELL
- Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation
- (2020) Liang Shi et al. FREE RADICAL BIOLOGY AND MEDICINE
- Imatinib and Dasatinib Provoke Mitochondrial Dysfunction Leading to Oxidative Stress in C2C12 Myotubes and Human RD Cells
- (2020) Jamal Bouitbir et al. Frontiers in Pharmacology
- Amorphous silica nanoparticles induce inflammation via activation of NLRP3 inflammasome and HMGB1/TLR4/MYD88/NF-kb signaling pathway in HUVEC cells
- (2020) Xuting Liu et al. JOURNAL OF HAZARDOUS MATERIALS
- Belinostat, at Its Clinically Relevant Concentrations, Inhibits Rifampicin Induced CYP3A4 and MDR1 Gene Expression
- (2019) Kodye L Abbott et al. MOLECULAR PHARMACOLOGY
- Factors Influencing Imatinib-Induced Hepatotoxicity
- (2019) Ji Min Han et al. Cancer Research and Treatment
- Inter-Individual Variation in CYP3A Activity Influences Lapatinib Bioactivation
- (2019) Jennifer E. Bissada et al. DRUG METABOLISM AND DISPOSITION
- Carbamazepine promotes specific stimuli-induced NLRP3 inflammasome activation and causes idiosyncratic liver injury in mice
- (2019) Zhilei Wang et al. ARCHIVES OF TOXICOLOGY
- Multitargeted kinase inhibitors imatinib, sorafenib and sunitinib perturb energy metabolism and cause cytotoxicity to cultured C2C12 skeletal muscle derived myotubes
- (2018) Vijaya L. Damaraju et al. BIOCHEMICAL PHARMACOLOGY
- Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment
- (2018) Zhi Wang et al. Journal of Neuroinflammation
- Dissecting the molecular pathophysiology of drug-induced liver injury
- (2018) Hui Ye et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Mesoporous silica nanoparticles induced hepatotoxicity via NLRP3 inflammasome activation and caspase-1-dependent pyroptosis
- (2018) Xuyao Zhang et al. Nanoscale
- New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
- (2018) Zhenyu Zhong et al. NATURE
- Novel sulphur-containing imatinib metabolites found by untargeted LC-HRMS analysis
- (2017) Ivo Vrobel et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure
- (2017) Benjamin L. Woolbright et al. JOURNAL OF HEPATOLOGY
- Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia
- (2017) Andreas Hochhaus et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis
- (2017) Franziska Paech et al. Frontiers in Pharmacology
- How Reactive Metabolites Induce an Immune Response That Sometimes Leads to an Idiosyncratic Drug Reaction
- (2016) Tiffany Cho et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Adjuvant Imatinib for High-Risk GI Stromal Tumor: Analysis of a Randomized Trial
- (2016) Heikki Joensuu et al. JOURNAL OF CLINICAL ONCOLOGY
- Mechanism and Regulation of NLRP3 Inflammasome Activation
- (2016) Yuan He et al. TRENDS IN BIOCHEMICAL SCIENCES
- Clinical Relevance of Biomarkers of Oxidative Stress
- (2015) Jeroen Frijhoff et al. ANTIOXIDANTS & REDOX SIGNALING
- Potassium efflux fires the canon: Potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways
- (2015) Jack Rivers-Auty et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Formation of reactive metabolites and management of tyrosine kinase inhibitor-induced hepatotoxicity: a literature review
- (2014) Yi Ling Teo et al. Expert Opinion on Drug Metabolism & Toxicology
- NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?
- (2014) Evan A. Bordt et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hepatotoxicity of Tyrosine Kinase Inhibitors: Clinical and Regulatory Perspectives
- (2013) Rashmi R. Shah et al. DRUG SAFETY
- Mitochondria-targeted drugs enhance Nlrp3 inflammasome-dependent IL-1β secretion in association with alterations in cellular redox and energy status
- (2013) Joshua Jabaut et al. FREE RADICAL BIOLOGY AND MEDICINE
- Calpains, mitochondria, and apoptosis
- (2012) M. A. Smith et al. CARDIOVASCULAR RESEARCH
- Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
- (2012) Kenichi Shimada et al. IMMUNITY
- Purinergic Receptor Antagonist A438079 Protects Against Acetaminophen-Induced Liver Injury by Inhibiting P450 Isoenzymes, Not by Inflammasome Activation
- (2012) Yuchao Xie et al. TOXICOLOGICAL SCIENCES
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- Clinical pharmacokinetics of tyrosine kinase inhibitors
- (2009) Nielka P. van Erp et al. CANCER TREATMENT REVIEWS
- Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome
- (2009) Avlin B. Imaeda et al. JOURNAL OF CLINICAL INVESTIGATION
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started