Alzheimer's‐like signaling in brains of COVID‐19 patients

The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning

(2021) Gabriel A. Erausquin et al.   Alzheimers & Dementia

Cerebellar Calcium-Binding Protein and Neurotrophin Receptor Defects in Down Syndrome and Alzheimer's Disease

(2021) Jennifer C. Miguel et al.   Frontiers in Aging Neuroscience

Age‐related calcium dysregulation linked with tau pathology and impaired cognition in non‐human primates

(2021) Dibyadeep Datta et al.   Alzheimers & Dementia

COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital

(2021) Kiran T Thakur et al.   BRAIN

Neuropathogenesis of acute coronavirus disease 2019

(2021) Shelli F. Farhadian et al.   CURRENT OPINION IN NEUROLOGY

Systemic Perturbations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine Responses

(2021) Nathan G. Lawler et al.   JOURNAL OF PROTEOME RESEARCH

Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia

(2021) Luca Braga et al.   NATURE

Dysregulation of brain and choroid plexus cell types in severe COVID-19

(2021) Andrew C. Yang et al.   NATURE

Kynurenic acid may underlie sex-specific immune responses to COVID-19

(2021) Yuping Cai et al.   Science Signaling

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

COVID-19 and the cardiovascular system

(2020) Ying-Ying Zheng et al.   Nature Reviews Cardiology

Role of brain renin angiotensin system in neurodegeneration: An update

(2020) Oyesiji A. Abiodun et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Intracellular calcium leak as a therapeutic target for RYR1-related myopathies

(2020) Alexander Kushnir et al.   ACTA NEUROPATHOLOGICA

Nervous system involvement after infection with COVID-19 and other coronaviruses

(2020) Yeshun Wu et al.   BRAIN BEHAVIOR AND IMMUNITY

Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis

(2020) Wei-jie Guan et al.   EUROPEAN RESPIRATORY JOURNAL

Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State

(2020) Matt Arentz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19

(2020) Yang Yang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

COVID-19, SARS and MERS: A neurological perspective

(2020) Koy Chong Ng Kee Kwong et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

(2020) Shaobo Shi et al.   JAMA Cardiology

Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

(2020) Chiara Agrati et al.   CELL DEATH AND DIFFERENTIATION

Pathogenesis of COVID-19-induced ARDS: implications for an aging population

(2020) Manuel A. Torres Acosta et al.   EUROPEAN RESPIRATORY JOURNAL

Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target

(2020) Haikel Dridi et al.   Nature Reviews Cardiology

SARS-CoV-2 Pathogenesis: Imbalance in the Renin-Angiotensin System Favors Lung Fibrosis

(2020) M. Victoria Delpino et al.   Frontiers in Cellular and Infection Microbiology

ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19

(2020) Riyue Bao et al.   Journal for ImmunoTherapy of Cancer

COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status

(2020) Tiffany Thomas et al.   JCI Insight

Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease

(2020) Amy F. T. Arnsten et al.   Alzheimers & Dementia

Mitochondria and microbiota dysfunction in COVID-19 pathogenesis

(2020) Jumana Saleh et al.   MITOCHONDRION

Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington’s disease

(2020) Haikel Dridi et al.   JCI Insight

The Evolutionary Expansion of mGluR3-NAAG-GCPII Signaling: Relevance to Human Intelligence and Cognitive Disorders

(2020) Amy F.T. Arnsten et al.   AMERICAN JOURNAL OF PSYCHIATRY

Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation

(2020) Haikel Dridi et al.   HUMAN MOLECULAR GENETICS

Blood Biomarkers for Detection of Brain Injury in COVID-19 Patients

(2020) Steven T. DeKosky et al.   JOURNAL OF NEUROTRAUMA

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

(2020) Jenny Meinhardt et al.   NATURE NEUROSCIENCE

The neuropathological diagnosis of Alzheimer’s disease

(2019) Michael A. DeTure et al.   Molecular Neurodegeneration

Ca2+/calmodulin-dependent protein kinase II promotes neurodegeneration caused by tau phosphorylated at Ser262/356 in a transgenic Drosophila model of tauopathy

(2017) Mikiko Oka et al.   JOURNAL OF BIOCHEMISTRY

Identification and pathological characterization of persistent asymptomatic Ebola virus infection in rhesus monkeys

(2017) Xiankun Zeng et al.   Nature Microbiology

Neurological Complications of Ebola Virus Infection

(2016) Bridgette Jeanne Billioux et al.   Neurotherapeutics

Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation

(2016) Stefan Matecki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiotensin-converting enzyme 2 is reduced in Alzheimer’s disease in association with increasing amyloid-β and tau pathology

(2016) Patrick Gavin Kehoe et al.   Alzheimers Research & Therapy

Angiotensin-(1-7) is Reduced and Inversely Correlates with Tau Hyperphosphorylation in Animal Models of Alzheimer’s Disease

(2015) Teng Jiang et al.   MOLECULAR NEUROBIOLOGY

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

(2015) David L Waning et al.   NATURE MEDICINE

Mitochondrial oxidative stress promotes atrial fibrillation

(2015) Wenjun Xie et al.   Scientific Reports

Role of Leaky Neuronal Ryanodine Receptors in Stress- Induced Cognitive Dysfunction

(2012) Xiaoping Liu et al.   CELL

Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice

(2010) Jian Shan et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

(2009) Andrew M Bellinger et al.   NATURE MEDICINE