标题
Advances in mRNA non-viral delivery approaches
作者
关键词
mRNA, Gene therapy, Delivery, Non-viral systems, Lipid nanoparticles, Polymers, Peptide-base vectors
出版物
ADVANCED DRUG DELIVERY REVIEWS
Volume 177, Issue -, Pages 113930
出版商
Elsevier BV
发表日期
2021-08-14
DOI
10.1016/j.addr.2021.113930
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Anionic Complex with Efficient Expression and Good Safety Profile for mRNA Delivery
- (2021) Eri Hamada et al. Pharmaceutics
- Nanoparticle-Mediated Cytoplasmic Delivery of Messenger RNA Vaccines: Challenges and Future Perspectives
- (2021) Zimei Wu et al. PHARMACEUTICAL RESEARCH
- Lipid Nanoparticles as Delivery Systems for RNA-Based Vaccines
- (2021) Basmah N. Aldosari et al. Pharmaceutics
- Clinical and immunological effects of mRNA vaccines in malignant diseases
- (2021) Annkristin Heine et al. Molecular Cancer
- Nucleic acid nanoparticles (NANPs) as molecular tools to direct desirable and avoid undesirable immunological effects
- (2021) M. Brittany Johnson et al. ADVANCED DRUG DELIVERY REVIEWS
- CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
- (2021) Julian D. Gillmore et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immune Responses to Viral Gene Therapy Vectors
- (2020) Jamie L. Shirley et al. MOLECULAR THERAPY
- Nanomedicines to Deliver mRNA: State of the Art and Future Perspectives
- (2020) Itziar Gómez-Aguado et al. Nanomaterials
- Optimization of an mRNA vaccine assisted with cyclodextrin-polyethyleneimine conjugates
- (2020) Lu Tan et al. Drug Delivery and Translational Research
- Therapeutic Cancer Vaccination with Ex Vivo RNA-Transfected Dendritic Cells—An Update
- (2020) Jan Dörrie et al. Pharmaceutics
- Opportunities and Challenges in the Delivery of mRNA-Based Vaccines
- (2020) Abishek Wadhwa et al. Pharmaceutics
- The promise of mRNA vaccines: a biotech and industrial perspective
- (2020) Nicholas A. C. Jackson et al. npj Vaccines
- Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
- (2020) Qiang Cheng et al. Nature Nanotechnology
- RNA delivery by extracellular vesicles in mammalian cells and its applications
- (2020) Killian O’Brien et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Ultrasound Assisted Exosomal Delivery of Tissue Responsive mRNA for Enhanced Efficacy and Minimized Off-Target Effects
- (2020) Wenqi Sun et al. Molecular Therapy-Nucleic Acids
- Long-term storage of lipid-like nanoparticles for mRNA delivery
- (2020) Pengxuan Zhao et al. Bioactive Materials
- Recent developments of RNA-based vaccines in cancer immunotherapy
- (2020) Elnaz Faghfuri et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Advances in Lipid Nanoparticles for mRNA-Based Cancer Immunotherapy
- (2020) Maria L. Guevara et al. Frontiers in Chemistry
- Addressing the Cold Reality of mRNA Vaccine Stability
- (2020) Daan J.A. Crommelin et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Non-viral COVID-19 vaccine delivery systems
- (2020) Kyung Soo Park et al. ADVANCED DRUG DELIVERY REVIEWS
- Preparation of Messenger RNA Nanomicelles via Non-Cytotoxic PEG-Polyamine Nanocomplex for Intracerebroventicular Delivery: A Proof-of-Concept Study in Mouse Models
- (2019) Long Chan et al. Nanomaterials
- Concise Review: Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering
- (2019) Zohreh Sadat Badieyan et al. Stem Cells Translational Medicine
- Recent Developments in mRNA-Based Protein Supplementation Therapy to Target Lung Diseases
- (2019) Itishri Sahu et al. MOLECULAR THERAPY
- Genome Editing with mRNA Encoding ZFN, TALEN, and Cas9
- (2019) Hong-Xia Zhang et al. MOLECULAR THERAPY
- A phase I/IIa study of the mRNA-based cancer immunotherapy CV9201 in patients with stage IIIB/IV non-small cell lung cancer
- (2019) Martin Sebastian et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Peptide-mediated delivery of therapeutic mRNA in ovarian cancer
- (2019) Dirk van den Brand et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Enhancement of Motor Function Recovery after Spinal Cord Injury in Mice by Delivery of Brain-Derived Neurotrophic Factor mRNA
- (2019) Samuel T. Crowley et al. Molecular Therapy-Nucleic Acids
- The Development of Functional Non-Viral Vectors for Gene Delivery
- (2019) Patil et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells
- (2019) Marco Maugeri et al. Nature Communications
- Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation
- (2019) Zhaogang Yang et al. Nature Biomedical Engineering
- Lipid Polymer Hybrid Nanomaterials for mRNA Delivery
- (2018) Weiyu Zhao et al. Cellular and Molecular Bioengineering
- CAR T-cell Therapy: A New Era in Cancer Immunotherapy
- (2018) Miliotou N. Androulla et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Efficient RNA drug delivery using red blood cell extracellular vesicles
- (2018) Waqas Muhammad Usman et al. Nature Communications
- Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility
- (2018) Jayesh A. Kulkarni et al. Nucleic Acid Therapeutics
- mRNA polyplexes with post-conjugated GALA peptides efficiently target, transfect and activate antigen presenting cells
- (2018) Bo Lou et al. BIOCONJUGATE CHEMISTRY
- Cell penetrating peptides: A concise review with emphasis on biomedical applications
- (2018) Hossein Derakhshankhah et al. BIOMEDICINE & PHARMACOTHERAPY
- Extracellular vesicles: intelligent delivery strategies for therapeutic applications
- (2018) Alice Pinheiro et al. JOURNAL OF CONTROLLED RELEASE
- Non-viral Delivery of Nucleic Acids: Insight Into Mechanisms of Overcoming Intracellular Barriers
- (2018) Mikhail Durymanov et al. Frontiers in Pharmacology
- Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA
- (2018) Mohammad Ariful Islam et al. Nature Biomedical Engineering
- mRNA-Based Genetic Reprogramming
- (2018) Luigi Warren et al. MOLECULAR THERAPY
- Systemic Administration and Targeted Delivery of Immunogenic Oncolytic Adenovirus Encapsulated in Extracellular Vesicles for Cancer Therapies
- (2018) Mariangela Garofalo et al. Viruses-Basel
- RNA sensors of the innate immune system and their detection of pathogens
- (2017) Nanhua Chen et al. IUBMB LIFE
- A Targeted and Stable Polymeric Nanoformulation Enhances Systemic Delivery of mRNA to Tumors
- (2017) Qixian Chen et al. MOLECULAR THERAPY
- Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
- (2017) Kapil Bahl et al. MOLECULAR THERAPY
- Systemic delivery of factor IX messenger RNA for protein replacement therapy
- (2017) Suvasini Ramaswamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide
- (2017) Vimal K. Udhayakumar et al. Advanced Healthcare Materials
- A new developing class of gene delivery: messenger RNA-based therapeutics
- (2017) Zhao Meng et al. Biomaterials Science
- The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery
- (2016) Xinwei Cheng et al. ADVANCED DRUG DELIVERY REVIEWS
- Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
- (2016) James C. Kaczmarek et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety
- (2016) Satoshi Uchida et al. BIOMATERIALS
- Non-viral nucleic acid delivery methods
- (2016) Igor Slivac et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Enhanced intranasal delivery of mRNA vaccine by overcoming the nasal epithelial barrier via intra- and paracellular pathways
- (2016) Man Li et al. JOURNAL OF CONTROLLED RELEASE
- Efficient mRNA delivery with graphene oxide-polyethylenimine for generation of footprint-free human induced pluripotent stem cells
- (2016) Hye Yeon Choi et al. JOURNAL OF CONTROLLED RELEASE
- Concise Review: Application of In Vitro Transcribed Messenger RNA for Cellular Engineering and Reprogramming: Progress and Challenges
- (2016) Heidrun Steinle et al. STEM CELLS
- Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment
- (2016) Hailati Aini et al. Scientific Reports
- Peptides for Specifically Targeting Nanoparticles to Cellular Organelles: Quo Vadis?
- (2015) Lauren D. Field et al. ACCOUNTS OF CHEMICAL RESEARCH
- Induction of HIV-1 gag specific immune responses by cationic micelles mediated delivery of gag mRNA
- (2015) Mengnan Zhao et al. DRUG DELIVERY
- Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles
- (2015) Miyuki Baba et al. JOURNAL OF CONTROLLED RELEASE
- Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
- (2015) Andreas Thess et al. MOLECULAR THERAPY
- Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases
- (2015) Akitsugu Matsui et al. Scientific Reports
- Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study
- (2015) Hubert Kübler et al. Journal for ImmunoTherapy of Cancer
- Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery
- (2014) Helen O. McCarthy et al. JOURNAL OF CONTROLLED RELEASE
- TAIL-seq: Genome-wide Determination of Poly(A) Tail Length and 3′ End Modifications
- (2014) Hyeshik Chang et al. MOLECULAR CELL
- mRNA-based therapeutics — developing a new class of drugs
- (2014) Ugur Sahin et al. NATURE REVIEWS DRUG DISCOVERY
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- Gene therapy on the move
- (2013) Kerstin B. Kaufmann et al. EMBO Molecular Medicine
- Lipid–polymer hybrid nanoparticles as a new generation therapeutic delivery platform: A review
- (2013) Kunn Hadinoto et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
- (2013) Anna Salvati et al. Nature Nanotechnology
- Reprogramming human fibroblasts to pluripotency using modified mRNA
- (2013) Pankaj K Mandal et al. Nature Protocols
- Toxicity profiling of several common RNAi-based nanomedicines: a comparative study
- (2013) Dalit Landesman-Milo et al. Drug Delivery and Translational Research
- Liposomal drug delivery systems: From concept to clinical applications
- (2012) Theresa M. Allen et al. ADVANCED DRUG DELIVERY REVIEWS
- The mannose receptor
- (2012) Luisa Martinez-Pomares JOURNAL OF LEUKOCYTE BIOLOGY
- Systemic Delivery of Modified mRNA Encoding Herpes Simplex Virus 1 Thymidine Kinase for Targeted Cancer Gene Therapy
- (2012) Yuhua Wang et al. MOLECULAR THERAPY
- Nanoparticle PEGylation for imaging and therapy
- (2011) Jesse V Jokerst et al. Nanomedicine
- Protein expression from exogenous mRNA: Uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway
- (2011) Christina Lorenz et al. RNA Biology
- Particle size and activation threshold: a new dimension of danger signaling
- (2010) L. Rettig et al. BLOOD
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting
- (2010) Shyh-Dar Li et al. JOURNAL OF CONTROLLED RELEASE
- High performance mRNA transfection through carbonate apatite–cationic liposome conjugates
- (2009) Fatema T. Zohra et al. BIOMATERIALS
- Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform
- (2008) Liangfang Zhang et al. ACS Nano
- Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
- (2008) Steven J. Howe et al. JOURNAL OF CLINICAL INVESTIGATION
- Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles
- (2008) Frank Alexis et al. MOLECULAR PHARMACEUTICS
- Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
- (2008) Johan Skog et al. NATURE CELL BIOLOGY
- Binding and Clustering of Glycosaminoglycans: A Common Property of Mono- and Multivalent Cell-Penetrating Compounds
- (2007) André Ziegler et al. BIOPHYSICAL JOURNAL
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now