标题
Nanoparticles for local delivery of siRNA in lung therapy
作者
关键词
Drug delivery, Nanoparticles, Nucleic acids administration, Lung cancer therapy
出版物
ADVANCED DRUG DELIVERY REVIEWS
Volume 179, Issue -, Pages 114038
出版商
Elsevier BV
发表日期
2021-11-04
DOI
10.1016/j.addr.2021.114038
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cellular and functional heterogeneity of the airway epithelium
- (2021) Jordan D. Davis et al. Mucosal Immunology
- Tyrosine-modified linear PEIs for highly efficacious and biocompatible siRNA delivery in vitro and in vivo
- (2021) Michael Karimov et al. Nanomedicine-Nanotechnology Biology and Medicine
- Nucleic acid delivery with extracellular vesicles
- (2021) Michaela Schulz-Siegmund et al. ADVANCED DRUG DELIVERY REVIEWS
- Epithelial Barrier Dysfunction in Chronic Respiratory Diseases
- (2021) François M. Carlier et al. Frontiers in Physiology
- In Vitro and in Vivo Behavior of Liposomes Decorated with PEGs with Different Chemical Features
- (2020) Francesca Mastrotto et al. MOLECULAR PHARMACEUTICS
- Small interfering RNA from the lab discovery to patients' recovery
- (2020) Marie Caillaud et al. JOURNAL OF CONTROLLED RELEASE
- Extracellular Vesicle-Mediated siRNA Delivery, Protein Delivery, and CFTR Complementation in Well-Differentiated Human Airway Epithelial Cells
- (2020) Brajesh K. Singh et al. Genes
- Exosomes as drug carriers for cancer therapy and challenges regarding exosome uptake
- (2020) Xiaoyin Zhao et al. BIOMEDICINE & PHARMACOTHERAPY
- Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles
- (2020) Lan Wu et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Copper (II) Metallodendrimers Combined with Pro-Apoptotic siRNAs as a Promising Strategy Against Breast Cancer Cells
- (2020) Natalia Sanz del Olmo et al. Pharmaceutics
- Recent Advances in Cell Penetrating Peptide-Based Anticancer Therapies
- (2019) Justine Habault et al. MOLECULES
- Lung Cancer
- (2019) Faria Nasim et al. MEDICAL CLINICS OF NORTH AMERICA
- Nanoparticle translocation and multi-organ toxicity: A particularly small problem
- (2019) Jennifer B. Raftis et al. Nano Today
- Polymeric Nanoparticles in Gene Therapy: New Avenues of Design and Optimization for Delivery Applications
- (2019) Raj Rai et al. Polymers
- Triple co-culture of human alveolar epithelium, endothelium and macrophages for studying the interaction of nanocarriers with the air-blood barrier
- (2019) Ana Costa et al. Acta Biomaterialia
- Recent advances in aerosol gene delivery systems using non-viral vectors for lung cancer therapy
- (2019) Ah Young Lee et al. Expert Opinion on Drug Delivery
- Recent Advances in Chitosan-Based Carriers for Gene Delivery
- (2019) Ye Cao et al. Marine Drugs
- Intratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer
- (2019) Yukimune Kanehira et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration
- (2019) Kaushik Thanki et al. JOURNAL OF CONTROLLED RELEASE
- Stimuli-Responsive Polymer–Prodrug Hybrid Nanoplatform for Multistage siRNA Delivery and Combination Cancer Therapy
- (2019) Phei Er Saw et al. NANO LETTERS
- Toxicity of Zero- and One-Dimensional Carbon Nanomaterials
- (2019) Iruthayapandi Selestin Raja et al. Nanomaterials
- Nanocarrier Lipid Composition Modulates the Impact of Pulmonary Surfactant Protein B (SP-B) on Cellular Delivery of siRNA
- (2019) Roberta Guagliardo et al. Pharmaceutics
- Characterization of spray dried powders with nucleic acid-containing PEI nanoparticles
- (2019) Tobias W.M. Keil et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- The Lord of the Lungs: The essential role of pulmonary surfactant upon inhalation of nanoparticles
- (2019) Cristina Garcia-Mouton et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Cell penetrating peptides: the potent multi-cargo intracellular carriers
- (2019) Kimia Kardani et al. Expert Opinion on Drug Delivery
- Effective mRNA pulmonary delivery by dry powder formulation of PEGylated synthetic KL4 peptide
- (2019) Yingshan Qiu et al. JOURNAL OF CONTROLLED RELEASE
- Biodegradable Polymers for Gene Delivery
- (2019) T. J. Thomas et al. MOLECULES
- Water-soluble substituted chitosan derivatives as technology platform for inhalation delivery of siRNA
- (2018) Victoria Capel et al. DRUG DELIVERY
- Association of Inhaled Corticosteroids and Long-Acting β-Agonists as Controller and Quick Relief Therapy With Exacerbations and Symptom Control in Persistent Asthma
- (2018) Diana M. Sobieraj et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Hybrid Lipid/Polymer Nanoparticles for Pulmonary Delivery of siRNA: Development and Fate Upon In Vitro Deposition on the Human Epithelial Airway Barrier
- (2018) Ivana d'Angelo et al. Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Ruthenium dendrimers as carriers for anticancer siRNA
- (2018) Sylwia Michlewska et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Exosome-Mediated Small RNA Delivery: A Novel Therapeutic Approach for Inflammatory Lung Responses
- (2018) Duo Zhang et al. MOLECULAR THERAPY
- Mechanisms of clathrin-mediated endocytosis
- (2018) Marko Kaksonen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Heterogeneity in Lung Cancer
- (2018) Vitor Manuel Leitão de Sousa et al. PATHOBIOLOGY
- Aerosol Delivery Devices for Obstructive Lung Diseases
- (2018) Roy A Pleasants et al. Respiratory Care
- Spray-Dried Nanoparticle-in-Microparticle Delivery Systems (NiMDS) for Gene Delivery, Comprising Polyethylenimine (PEI)-Based Nanoparticles in a Poly(Vinyl Alcohol) Matrix
- (2018) Jan Schulze et al. Small
- Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy
- (2018) Pieterjan Merckx et al. Acta Biomaterialia
- Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells
- (2018) Yudong Song et al. BIOMATERIALS
- Dendrimer as a new potential carrier for topical delivery of siRNA: A comparative study of dendriplex vs. lipoplex for delivery of TNF-α siRNA
- (2018) Palpandi Pandi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The first line of defence: insights into mechanisms and relevance of phagocytosis in epithelial cells
- (2018) Juliane Günther et al. Seminars in Immunopathology
- Exosomes From Human Cardiac Progenitor Cells for Therapeutic Applications: Development of a GMP-Grade Manufacturing Method
- (2018) Gabriella Andriolo et al. Frontiers in Physiology
- Non-small-cell lung cancer homing peptide-labeled dendrimers selectively transfect lung cancer cells
- (2018) Gregory E Holt et al. Immunotherapy
- A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy
- (2018) Yiwen Dong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying
- (2017) Monica Agnoletti et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Aptamer-targeted delivery of Bcl-xL shRNA using alkyl modified PAMAM dendrimers into lung cancer cells
- (2017) Sara Ayatollahi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- TPP-dendrimer nanocarriers for siRNA delivery to the pulmonary epithelium and their dry powder and metered-dose inhaler formulations
- (2017) Elizabeth Bielski et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Nebulized anionic guanidinylated O-carboxymethyl chitosan/N-2-hydroxypropyltimehyl ammonium chloride chitosan nanoparticles for siRNA pulmonary delivery: preparation, characterization and in vitro evaluation
- (2017) Suhui Ni et al. JOURNAL OF DRUG TARGETING
- Lung cancer: current therapies and new targeted treatments
- (2017) Fred R Hirsch et al. LANCET
- Lipid Nanoparticle Systems for Enabling Gene Therapies
- (2017) Pieter R. Cullis et al. MOLECULAR THERAPY
- Protein corona: implications for nanoparticle interactions with pulmonary cells
- (2017) Nagarjun V. Konduru et al. Particle and Fibre Toxicology
- Sub-chronic inhalation of lead oxide nanoparticles revealed their broad distribution and tissue-specific subcellular localization in target organs
- (2017) J. Dumková et al. Particle and Fibre Toxicology
- Optimizing drug delivery in COPD: The role of inhaler devices
- (2017) Paola Rogliani et al. RESPIRATORY MEDICINE
- A Poly(Propyleneimine) Dendrimer-Based Polyplex-System for Single-Chain Antibody-Mediated Targeted Delivery and Cellular Uptake of SiRNA
- (2017) Stefanie Tietze et al. Small
- Co-culture of human alveolar epithelial (hAELVi) and macrophage (THP-1) cell lines
- (2017) Stephanie Kletting ALTEX-Alternatives to Animal Experimentation
- Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery
- (2017) Rong-Qiao Cai et al. Oncotarget
- Polymorphisms of CCNB1 Associated With the Clinical Outcomes of Platinum-Based Chemotherapy in Chinese NSCLC Patients
- (2017) Di Liu et al. Journal of Cancer
- Mucoactive and antioxidant medicines for COPD: consensus of a group of Chinese pulmonary physicians
- (2017) Xixin Yan et al. International Journal of Chronic Obstructive Pulmonary Disease
- Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene
- (2017) Ivan V. Chernikov et al. Molecular Therapy-Nucleic Acids
- Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation
- (2017) Craig S. Schneider et al. Science Advances
- Lung morphometry: the link between structure and function
- (2016) Ewald R. Weibel CELL AND TISSUE RESEARCH
- EGF-modified mPEG-PLGA-PLL nanoparticle for delivering doxorubicin combined with Bcl-2 siRNA as a potential treatment strategy for lung cancer
- (2016) Xiangyu Zhang et al. DRUG DELIVERY
- Dry powder inhalation: past, present and future
- (2016) A. H. de Boer et al. Expert Opinion on Drug Delivery
- Exosomes from iPSCs Delivering siRNA Attenuate Intracellular Adhesion Molecule-1 Expression and Neutrophils Adhesion in Pulmonary Microvascular Endothelial Cells
- (2016) Zhihai Ju et al. INFLAMMATION
- Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice
- (2016) Jens Lipka et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The Evolution of Pressurized Metered-Dose Inhalers from Early to Modern Devices
- (2016) Nicolas Roche et al. Journal of Aerosol Medicine and Pulmonary Drug Delivery
- A novel tyrosine-modified low molecular weight polyethylenimine (P10Y) for efficient siRNA delivery in vitro and in vivo
- (2016) Alexander Ewe et al. JOURNAL OF CONTROLLED RELEASE
- Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside
- (2016) Yingshan Qiu et al. MOLECULES
- Nanoparticles in the lung and their protein corona: the few proteins that count
- (2016) Harry Whitwell et al. Nanotoxicology
- Classification and Pathology of Lung Cancer
- (2016) Min Zheng Surgical Oncology Clinics of North America
- Epidemiology of Lung Cancer
- (2016) Yousheng Mao et al. Surgical Oncology Clinics of North America
- Functional Delivery of siRNA by Disulfide-Constrained Cyclic Amphipathic Peptides
- (2016) Jade J. Welch et al. ACS Medicinal Chemistry Letters
- MDM2 knockdown mediated by a triazine-modified dendrimer in the treatment of non-small cell lung cancer
- (2016) Quan Huang et al. Oncotarget
- Proteomic and Lipidomic Analysis of Nanoparticle Corona upon Contact with Lung Surfactant Reveals Differences in Protein, but Not Lipid Composition
- (2015) Simon Sebastian Raesch et al. ACS Nano
- AFREZZA® (insulin human) Inhalation Powder: A Review in Diabetes Mellitus
- (2015) Esther S. Kim et al. DRUGS
- Targeted lung cancer therapy: preparation and optimization of transferrin-decorated nanostructured lipid carriers as novel nanomedicine for co-delivery of anticancer drugs and DNA
- (2015) Zhenyu Shao et al. International Journal of Nanomedicine
- Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (A). Mechanisms of interaction
- (2015) Maksim Ionov et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan–poly(ethylene imine) hybrid nanoparticles: A mechanistic insight
- (2015) Héloïse Ragelle et al. JOURNAL OF CONTROLLED RELEASE
- Nanoparticle-mediated delivery of siRNA for effective lung cancer therapy
- (2015) Young-Dong Kim et al. Nanomedicine
- Stability, Intracellular Delivery, and Release of siRNA from Chitosan Nanoparticles Using Different Cross-Linkers
- (2015) Maria Abdul Ghafoor Raja et al. PLoS One
- Expression of EGFR Is Closely Related to Reduced 3-Year Survival Rate in Chinese Female NSCLC
- (2015) Bing Li MEDICAL SCIENCE MONITOR
- Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer
- (2015) Suniti Misra et al. Frontiers in Immunology
- Size Influences the Effect of Hydrophobic Nanoparticles on Lung Surfactant Model Systems
- (2014) Mridula V. Dwivedi et al. BIOPHYSICAL JOURNAL
- The folate receptor as a rational therapeutic target for personalized cancer treatment
- (2014) Yehuda G. Assaraf et al. DRUG RESISTANCE UPDATES
- Nebulizers for drug delivery to the lungs
- (2014) Andrew R Martin et al. Expert Opinion on Drug Delivery
- The Cell Line NCl-H441 Is a Useful in Vitro Model for Transport Studies of Human Distal Lung Epithelial Barrier
- (2014) Johanna J. Salomon et al. MOLECULAR PHARMACEUTICS
- Mad2 Checkpoint Gene Silencing Using Epidermal Growth Factor Receptor-Targeted Chitosan Nanoparticles in Non-Small Cell Lung Cancer Model
- (2014) Ana Vanessa Nascimento et al. MOLECULAR PHARMACEUTICS
- Poly(amidoamine) Dendrimer Nanocarriers and Their Aerosol Formulations for siRNA Delivery to the Lung Epithelium
- (2014) Denise S. Conti et al. MOLECULAR PHARMACEUTICS
- Nanotoxicity: a key obstacle to clinical translation of siRNA-based nanomedicine
- (2014) Hui Yi Xue et al. Nanomedicine
- Increasing Hydrophobicity of Nanoparticles Intensifies Lung Surfactant Film Inhibition and Particle Retention
- (2014) Russell P. Valle et al. ACS Sustainable Chemistry & Engineering
- A sight on the current nanoparticle-based gene delivery vectors
- (2014) Solmaz Dizaj et al. Nanoscale Research Letters
- Physicochemical Properties of Nanoparticles Regulate Translocation across Pulmonary Surfactant Monolayer and Formation of Lipoprotein Corona
- (2013) Guoqing Hu et al. ACS Nano
- Nanoparticle diffusion in respiratory mucus from humans without lung disease
- (2013) Benjamin S. Schuster et al. BIOMATERIALS
- In vivo tumor targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models
- (2013) João Conde et al. BIOMATERIALS
- Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors
- (2013) Shanthi Ganesh et al. BIOMATERIALS
- Hydrophobic Pulmonary Surfactant Proteins SP-B and SP-C Induce Pore Formation in Planar Lipid Membranes: Evidence for Proteolipid Pores
- (2013) Elisa Parra et al. BIOPHYSICAL JOURNAL
- Apoptosis-Related Gene Transcription in Human A549 Lung Cancer Cells via A3Adenosine Receptor
- (2013) Hitomi Kamiya et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Alveolar epithelial cells: Master regulators of lung homeostasis
- (2013) Loïc Guillot et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Nebulised siRNA encapsulated crosslinked chitosan nanoparticles for pulmonary delivery
- (2013) Ketan Sharma et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Mucus as a barrier to lipophilic drugs
- (2013) Hakon H. Sigurdsson et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo
- (2013) Caihua Xu et al. PLoS One
- Pulmonary drug delivery: from generating aerosols to overcoming biological barriers—therapeutic possibilities and technological challenges
- (2013) Christian A Ruge et al. Lancet Respiratory Medicine
- Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis
- (2013) Kenneth L Clark et al. Molecular Therapy-Nucleic Acids
- Biomedical applications of carboxymethyl chitosans
- (2012) Laxmi Upadhyaya et al. CARBOHYDRATE POLYMERS
- Biodegradable Nanoparticles of mPEG-PLGA-PLL Triblock Copolymers as Novel Non-Viral Vectors for Improving siRNA Delivery and Gene Silencing
- (2012) Jing Du et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells
- (2012) Wu-Chou Su et al. International Journal of Nanomedicine
- An inhalable β2-adrenoceptor ligand-directed guanidinylated chitosan carrier for targeted delivery of siRNA to lung
- (2012) Yongfeng Luo et al. JOURNAL OF CONTROLLED RELEASE
- PLGA-based nanoparticles: An overview of biomedical applications
- (2012) Fabienne Danhier et al. JOURNAL OF CONTROLLED RELEASE
- The Interplay of Lung Surfactant Proteins and Lipids Assimilates the Macrophage Clearance of Nanoparticles
- (2012) Christian A. Ruge et al. PLoS One
- Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus
- (2012) J. Kirch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells
- (2012) JeanClare Seagrave et al. RESPIRATORY RESEARCH
- A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia
- (2012) B. Button et al. SCIENCE
- Pulmonary delivery of therapeutic siRNA
- (2011) Jenny Ka-Wing Lam et al. ADVANCED DRUG DELIVERY REVIEWS
- Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles
- (2011) Hai Wang et al. BIOMATERIALS
- Roles of AKT1 and AKT2 in non-small cell lung cancer cell survival, growth, and migration
- (2011) Myoung W. Lee et al. CANCER SCIENCE
- Lung Cancer: Epidemiology, Etiology, and Prevention
- (2011) Charles S. Dela Cruz et al. CLINICS IN CHEST MEDICINE
- Cellular uptake mechanism and knockdown activity of siRNA-loaded biodegradable DEAPA-PVA-g-PLGA nanoparticles
- (2011) Markus Benfer et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Epithelial cells and airway diseases
- (2011) David Proud et al. IMMUNOLOGICAL REVIEWS
- Influence of particle size on regional lung deposition – What evidence is there?
- (2011) Thiago C. Carvalho et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Controlled pulmonary drug and gene delivery using polymeric nano-carriers
- (2011) Moritz Beck-Broichsitter et al. JOURNAL OF CONTROLLED RELEASE
- Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge—an ex vivo and in silico approach
- (2011) Julian Kirch et al. JOURNAL OF CONTROLLED RELEASE
- Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA
- (2011) Ditte Krohn Jensen et al. JOURNAL OF CONTROLLED RELEASE
- Innovative strategy for treatment of lung cancer: targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA
- (2011) Oleh Taratula et al. JOURNAL OF DRUG TARGETING
- Delivery of siRNA Therapeutics: Barriers and Carriers
- (2010) Jie Wang et al. AAPS Journal
- Proton Sponge Trick for pH-Sensitive Disassembly of Polyethylenimine-Based siRNA Delivery Systems
- (2010) Gaelle Creusat et al. BIOCONJUGATE CHEMISTRY
- Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung
- (2010) Melanie Günther et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: Quality by design optimization and characterization
- (2010) Dongmei Cun et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Chitosan as a carrier for targeted delivery of small interfering RNA
- (2010) Walter E. Rudzinski et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Rational design of cationic lipids for siRNA delivery
- (2010) Sean C Semple et al. NATURE BIOTECHNOLOGY
- Deposition and biokinetics of inhaled nanoparticles
- (2010) Marianne Geiser et al. Particle and Fibre Toxicology
- Lipid-like materials for low-dose, in vivo gene silencing
- (2010) K. T. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNAi-mediated suppression of constitutive pulmonary gene expression by small interfering RNA in mice
- (2010) Birgitt Gutbier et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- A safety and tolerability study of differently-charged nanoparticles for local pulmonary drug delivery
- (2010) Oshrat Harush-Frenkel et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Interaction of Gold Nanoparticles with Common Human Blood Proteins
- (2009) Silvia H. De Paoli Lacerda et al. ACS Nano
- Chitosan-based formulations for delivery of DNA and siRNA
- (2009) Shirui Mao et al. ADVANCED DRUG DELIVERY REVIEWS
- Mechanisms of Alveolar Epithelial Translocation of a Defined Population of Nanoparticles
- (2009) Nazanin R. Yacobi et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The suppression of lung tumorigenesis by aerosol-delivered folate–chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway
- (2009) Hu-Lin Jiang et al. BIOMATERIALS
- Endocytosisviacaveolae: alternative pathway with distinct cellular compartments to avoid lysosomal degradation?
- (2009) Anna L. Kiss et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation
- (2009) Ditte Marie Krohn Jensen et al. JOURNAL OF CONTROLLED RELEASE
- Oxidative stress and inflammation response after nanoparticle exposure: differences between human lung cell monocultures and an advanced three-dimensional model of the human epithelial airways
- (2009) L. Muller et al. Journal of the Royal Society Interface
- Nonviral siRNA Delivery to the Lung: Investigation of PEG−PEI Polyplexes and Their In Vivo Performance
- (2009) Olivia M. Merkel et al. MOLECULAR PHARMACEUTICS
- Expression profiling of integrins in lung cancer cells
- (2009) Linlang Guo et al. PATHOLOGY RESEARCH AND PRACTICE
- Effective Treatment of Respiratory Alphaherpesvirus Infection Using RNA Interference
- (2009) Amy Fulton et al. PLoS One
- In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application
- (2009) Andrea Beyerle et al. TOXICOLOGY IN VITRO
- Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
- (2008) Samuel K. Lai et al. ADVANCED DRUG DELIVERY REVIEWS
- Barrier properties of mucus
- (2008) Richard A. Cone ADVANCED DRUG DELIVERY REVIEWS
- Extracellular barriers in respiratory gene therapy
- (2008) Niek Sanders et al. ADVANCED DRUG DELIVERY REVIEWS
- Interactions of nanoparticles with pulmonary structures and cellular responses
- (2008) Christian Mühlfeld et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Intrapulmonary Delivery of XCL1-Targeting Small Interfering RNA in Mice Chronically Infected withMycobacterium tuberculosis
- (2008) Adrian G. Rosas-Taraco et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Polyethylenimine In Medicinal Chemistry
- (2008) Paola Vicennati et al. CURRENT MEDICINAL CHEMISTRY
- Pulmonary cell culture models to study the safety and efficacy of innovative aerosol medicines
- (2008) Michael Bur et al. Expert Opinion on Drug Delivery
- Inhalable siRNA: Potential as a Therapeutic Agent in the Lungs
- (2008) Niamh Durcan et al. MOLECULAR PHARMACEUTICS
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
- Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: Establishment of structure–activity relationships in vitro
- (2007) Oliver Germershaus et al. JOURNAL OF CONTROLLED RELEASE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More