标题
Nanoparticle-mediated delivery of siRNA for effective lung cancer therapy
作者
关键词
-
出版物
Nanomedicine
Volume 10, Issue 7, Pages 1165-1188
出版商
Future Medicine Ltd
发表日期
2015-05-01
DOI
10.2217/nnm.14.214
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Highly effective inhibition of lung cancer growth and metastasis by systemic delivery of siRNA via multimodal mesoporous silica-based nanocarrier
- (2014) Yijie Chen et al. BIOMATERIALS
- Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs
- (2014) Lin Zhu et al. BIOMATERIALS
- Cationic Lipid-Assisted Polymeric Nanoparticle Mediated GATA2 siRNA Delivery for Synthetic Lethal Therapy of KRAS Mutant Non-Small-Cell Lung Carcinoma
- (2014) Song Shen et al. MOLECULAR PHARMACEUTICS
- Mad2 Checkpoint Gene Silencing Using Epidermal Growth Factor Receptor-Targeted Chitosan Nanoparticles in Non-Small Cell Lung Cancer Model
- (2014) Ana Vanessa Nascimento et al. MOLECULAR PHARMACEUTICS
- Poly(amidoamine) Dendrimer Nanocarriers and Their Aerosol Formulations for siRNA Delivery to the Lung Epithelium
- (2014) Denise S. Conti et al. MOLECULAR PHARMACEUTICS
- Synthetic Lethal Therapy for KRAS Mutant Non-small-cell Lung Carcinoma with Nanoparticle-mediated CDK4 siRNA Delivery
- (2014) Cheng-Qiong Mao et al. MOLECULAR THERAPY
- Delivery of Therapeutic siRNA to the Lung Endothelium via Novel Lipoplex Formulation DACC
- (2014) V Fehring et al. MOLECULAR THERAPY
- Codelivery of an Optimal Drug/siRNA Combination Using Mesoporous Silica Nanoparticles To Overcome Drug Resistance in Breast Cancer in Vitro and in Vivo
- (2013) Huan Meng et al. ACS Nano
- Gene Silencing in a Mouse Lung Metastasis Model by an Inhalable Dry Small Interfering RNA Powder Prepared Using the Supercritical Carbon Dioxide Technique
- (2013) Tomoyuki Okuda et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Codelivery of mTERT siRNA and paclitaxel by chitosan-based nanoparticles promoted synergistic tumor suppression
- (2013) Wei Wei et al. BIOMATERIALS
- In vivo tumor targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models
- (2013) João Conde et al. BIOMATERIALS
- Induction of apoptosis in non-small cell lung cancer by downregulation of MDM2 using pH-responsive PMPC-b-PDPA/siRNA complex nanoparticles
- (2013) Haijun Yu et al. BIOMATERIALS
- Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors
- (2013) Shanthi Ganesh et al. BIOMATERIALS
- Rigid nanoparticle-based delivery of anti-cancer siRNA: Challenges and opportunities
- (2013) Zhiyong Wang et al. BIOTECHNOLOGY ADVANCES
- Nanooncology: The future of cancer diagnosis and therapy
- (2013) Avnesh S. Thakor et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Magnetic Nanoparticles: Surface Effects and Properties Related to Biomedicine Applications
- (2013) Bashar Issa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA
- (2013) Oleh Taratula et al. JOURNAL OF CONTROLLED RELEASE
- Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition
- (2013) Marie-Elise Bonnet et al. JOURNAL OF CONTROLLED RELEASE
- A Biodegradable Polymersome Containing Bcl-xL siRNA and Doxorubicin as a Dual Delivery Vehicle for a Synergistic Anticancer Effect
- (2013) Hyun-Ouk Kim et al. MACROMOLECULAR BIOSCIENCE
- iRGD Conjugated TPGS Mediates Codelivery of Paclitaxel and Survivin shRNA for the Reversal of Lung Cancer Resistance
- (2013) Jianan Shen et al. MOLECULAR PHARMACEUTICS
- Effective Delivery of siRNA into Cancer Cells and Tumors Using Well-Defined Biodegradable Cationic Star Polymers
- (2013) Cyrille Boyer et al. MOLECULAR PHARMACEUTICS
- Codelivery of VEGF siRNA and Gemcitabine Monophosphate in a Single Nanoparticle Formulation for Effective Treatment of NSCLC
- (2013) Yuan Zhang et al. MOLECULAR THERAPY
- Enhanced Intrapulmonary Delivery of Anticancer siRNA for Lung Cancer Therapy Using Cationic Ethylphosphocholine-based Nanolipoplexes
- (2013) Gayong Shim et al. MOLECULAR THERAPY
- Intravenous Delivery of siRNA Targeting CD47 Effectively Inhibits Melanoma Tumor Growth and Lung Metastasis
- (2013) Yuhua Wang et al. MOLECULAR THERAPY
- Delivery materials for siRNA therapeutics
- (2013) Rosemary Kanasty et al. NATURE MATERIALS
- Weighing up gene delivery
- (2013) Ameya R. Kirtane et al. Nature Nanotechnology
- Cationic Bovine Serum Albumin Based Self-Assembled Nanoparticles as siRNA Delivery Vector for Treating Lung Metastatic Cancer
- (2013) Jianfeng Han et al. Small
- Combination of siRNA-directed Gene Silencing With Cisplatin Reverses Drug Resistance in Human Non-small Cell Lung Cancer
- (2013) Shanthi Ganesh et al. Molecular Therapy-Nucleic Acids
- Gene Silencing by Gold Nanoshell-Mediated Delivery and Laser-Triggered Release of Antisense Oligonucleotide and siRNA
- (2012) Ryan Huschka et al. ACS Nano
- Asymmetric liposome particles with highly efficient encapsulation of siRNA and without nonspecific cell penetration suitable for target-specific delivery
- (2012) Amir Abbas Mokhtarieh et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Co-delivery of paclitaxel and survivin shRNA by pluronic P85-PEI/TPGS complex nanoparticles to overcome drug resistance in lung cancer
- (2012) Jianan Shen et al. BIOMATERIALS
- Biodegradable Nanoparticles of mPEG-PLGA-PLL Triblock Copolymers as Novel Non-Viral Vectors for Improving siRNA Delivery and Gene Silencing
- (2012) Jing Du et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nanoparticle Delivery of Pooled siRNA for Effective Treatment of Non-Small Cell Lung Caner
- (2012) Yang Yang et al. MOLECULAR PHARMACEUTICS
- Targeting Strategies for Multifunctional Nanoparticles in Cancer Imaging and Therapy
- (2012) Mi Kyung Yu et al. Theranostics
- Traceable Multifunctional Micellar Nanocarriers for Cancer-Targeted Co-delivery of MDR-1 siRNA and Doxorubicin
- (2011) Xiao-Bing Xiong et al. ACS Nano
- Nanoparticle Delivery of Cancer Drugs
- (2011) Andrew Z. Wang et al. Annual Review of Medicine
- Tumor-targeting magnetic lipoplex delivery of short hairpin RNA suppresses IGF-1R overexpression of lung adenocarcinoma A549 cells in vitro and in vivo
- (2011) Chunmao Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Active targeting of RGD-conjugated bioreducible polymer for delivery of oncolytic adenovirus expressing shRNA against IL-8 mRNA
- (2011) Jaesung Kim et al. BIOMATERIALS
- Lung cancer: New biological insights and recent therapeutic advances
- (2011) Suresh S. Ramalingam et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Hydrophobic Oxime Ethers: A Versatile Class of pDNA and siRNA Transfection Lipids
- (2011) Souvik Biswas et al. ChemMedChem
- Progress and Prospects of Polyplex Nanomicelles for Plasmid DNA Delivery
- (2011) Keiji Itaka et al. CURRENT GENE THERAPY
- Cationic solid lipid nanoparticles for co-delivery of paclitaxel and siRNA
- (2011) Yong Hee Yu et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases
- (2011) Zhe-Sheng Chen et al. FEBS Journal
- The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer
- (2011) Kenneth D. Tew et al. FREE RADICAL BIOLOGY AND MEDICINE
- Classical resistance mechanisms
- (2011) W. Jäger INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
- Application of Magnetic Nanoparticles to Gene Delivery
- (2011) Daisuke Kami et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Aerosol delivery of spermine-based poly(amino ester)/Akt1 shRNA complexes for lung cancer gene therapy
- (2011) Hu-Lin Jiang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Recent progress in non-viral nucleic acids delivery
- (2011) Aliasger K. Salem et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment
- (2011) Norihito Yonenaga et al. JOURNAL OF CONTROLLED RELEASE
- Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor
- (2011) Jun Li et al. JOURNAL OF CONTROLLED RELEASE
- Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA
- (2011) Ditte Krohn Jensen et al. JOURNAL OF CONTROLLED RELEASE
- Innovative strategy for treatment of lung cancer: targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA
- (2011) Oleh Taratula et al. JOURNAL OF DRUG TARGETING
- Systemic Delivery of siRNA via LCP Nanoparticle Efficiently Inhibits Lung Metastasis
- (2011) Yang Yang et al. MOLECULAR THERAPY
- Gene Silencing Activity of siRNA Polyplexes Based on ThiolatedN,N,N-Trimethylated Chitosan
- (2010) Amir K. Varkouhi et al. BIOCONJUGATE CHEMISTRY
- Transfection Efficiency of Cationic Lipids with Different Hydrophobic Domains in Gene Delivery
- (2010) DeFu Zhi et al. BIOCONJUGATE CHEMISTRY
- The synergistic effect of hierarchical assemblies of siRNA and chemotherapeutic drugs co-delivered into hepatic cancer cells
- (2010) Nuo Cao et al. BIOMATERIALS
- High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: Quality by design optimization and characterization
- (2010) Dongmei Cun et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Enhanced cellular internalization and gene silencing with a series of cationic dendron-multiwalled carbon nanotube:siRNA complexes
- (2010) Khuloud T. Al-Jamal et al. FASEB JOURNAL
- Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug
- (2010) Gayong Shim et al. JOURNAL OF CONTROLLED RELEASE
- Efficient inhibition of lung cancer in murine model by plasmid-encoding VEGF short hairpin RNA in combination with low-dose DDP
- (2010) Yong P Ma et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- In Vivo Imaging of RNA Interference
- (2010) H. Hong et al. JOURNAL OF NUCLEAR MEDICINE
- Unknown
- (2010) Jennifer Ziello et al. MOLECULAR MEDICINE
- Nanoparticles Modified With Tumor-targeting scFv Deliver siRNA and miRNA for Cancer Therapy
- (2010) Yunching Chen et al. MOLECULAR THERAPY
- Functional nanoparticles for molecular imaging guided gene delivery
- (2010) Gang Liu et al. Nano Today
- Understanding and overcoming major barriers in cancer nanomedicine
- (2010) Shuming Nie Nanomedicine
- Cationic lipo-thiophosphoramidates for gene delivery: synthesis, physico-chemical characterization and gene transfection activity – comparison with lipo-phosphoramidates
- (2010) Aurore Fraix et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance
- (2010) O. B. Garbuzenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multifunctional Nanomedicine Platform for Cancer Specific Delivery of siRNA by Superparamagnetic Iron Oxide Nanoparticles-Dendrimer Complexes
- (2010) Oleh Taratula et al. Current Drug Delivery
- siRNA delivery systems for cancer treatment
- (2009) Yu-Kyoung Oh et al. ADVANCED DRUG DELIVERY REVIEWS
- The suppression of lung tumorigenesis by aerosol-delivered folate–chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway
- (2009) Hu-Lin Jiang et al. BIOMATERIALS
- MRI-visible polymeric vector bearing CD3 single chain antibody for gene delivery to T cells for immunosuppression
- (2009) Guihua Chen et al. BIOMATERIALS
- The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
- (2009) Yogesh B. Patil et al. BIOMATERIALS
- WT1 gene silencing by aerosol delivery of PEI–RNAi complexes inhibits B16-F10 lung metastases growth
- (2009) D E Zamora-Avila et al. CANCER GENE THERAPY
- Nanocarriers’ entry into the cell: relevance to drug delivery
- (2009) Hervé Hillaireau et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mitotic Deregulation by Survivin in ErbB2-Overexpressing Breast Cancer Cells Contributes to Taxol Resistance
- (2009) J. Lu et al. CLINICAL CANCER RESEARCH
- Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells
- (2009) Dhananjay Jere et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Endocytosisviacaveolae: alternative pathway with distinct cellular compartments to avoid lysosomal degradation?
- (2009) Anna L. Kiss et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Hyaluronic Acid-Modified DOTAP/DOPE Liposomes for the Targeted Delivery of Anti-Telomerase siRNA to CD44-Expressing Lung Cancer Cells
- (2009) Sebastian Taetz et al. OLIGONUCLEOTIDES
- Cancer therapy: Small 10/2009
- (2009) Jennifer E. Podesta et al. Small
- Poly(ester amine)-mediated, Aerosol-delivered Akt1 Small Interfering RNA Suppresses Lung Tumorigenesis
- (2008) Cheng-Xiong Xu et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- P-Glycoprotein Limits Oral Availability, Brain Penetration, and Toxicity of an Anionic Drug, the Antibiotic Salinomycin
- (2008) J. S. Lagas et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Poly(β-amino ester) as a carrier for si/shRNA delivery in lung cancer cells
- (2008) Dhananjay Jere et al. BIOMATERIALS
- Akt1 silencing efficiencies in lung cancer cells by sh/si/ssiRNA transfection using a reductable polyspermine carrier
- (2008) Dhananjay Jere et al. BIOMATERIALS
- An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor
- (2008) Sumio Chono et al. JOURNAL OF CONTROLLED RELEASE
- Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy
- (2008) Juliane Nguyen et al. JOURNAL OF CONTROLLED RELEASE
- Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer
- (2008) E. Kawata et al. MOLECULAR CANCER THERAPEUTICS
- Inhalable siRNA: Potential as a Therapeutic Agent in the Lungs
- (2008) Niamh Durcan et al. MOLECULAR PHARMACEUTICS
- Anticancer Therapeutics: Targeting Macromolecules and Nanocarriers to Hyaluronan or CD44, a Hyaluronan Receptor
- (2008) Virginia M. Platt et al. MOLECULAR PHARMACEUTICS
- Efficient Oncogene Silencing and Metastasis Inhibition via Systemic Delivery of siRNA
- (2008) Shyh-Dar Li et al. MOLECULAR THERAPY
- Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer
- (2008) Maha Saad et al. Nanomedicine
- Intratracheal Versus Intravenous Liposomal Delivery of siRNA, Antisense Oligonucleotides and Anticancer Drug
- (2008) Olga B. Garbuzenko et al. PHARMACEUTICAL RESEARCH
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