Endothelial notch signaling is essential to prevent hepatic vascular malformations in mice

Mutations in NOTCH1 Cause Adams-Oliver Syndrome

(2014) Anna-Barbara Stittrich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals

(2014) H. Lindskog et al.   DEVELOPMENT

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice

(2014) C. M. Nielsen et al.   DEVELOPMENT

Emerging roles of Notch signaling in liver disease

(2014) Fabian Geisler et al.   HEPATOLOGY

De Novo Cerebrovascular Malformation in the Adult Mouse After Endothelial Alk1 Deletion and Angiogenic Stimulation

(2014) Wanqiu Chen et al.   STROKE

Notch controls retinal blood vessel maturation and quiescence

(2013) M. Ehling et al.   DEVELOPMENT

Notch as a hub for signaling in angiogenesis

(2013) Rui Benedito et al.   EXPERIMENTAL CELL RESEARCH

RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome

(2012) Susan J. Hassed et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Disruption of Notch1 Induces Vascular Remodeling, Intussusceptive Angiogenesis, and Angiosarcomas in Livers of Mice

(2012) Michael T. Dill et al.   GASTROENTEROLOGY

Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling

(2012) Rui Benedito et al.   NATURE

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Notch4 Normalization Reduces Blood Vessel Size in Arteriovenous Malformations

(2012) P. A. Murphy et al.   Science Translational Medicine

Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac

(2011) Jessica N Copeland et al.   BMC DEVELOPMENTAL BIOLOGY

Interaction between alk1 and blood flow in the development of arteriovenous malformations

(2011) P. Corti et al.   DEVELOPMENT

Endothelial Smad4 Maintains Cerebrovascular Integrity by Activating N-Cadherin through Cooperation with Notch

(2011) Fangfei Li et al.   DEVELOPMENTAL CELL

Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice

(2011) Zhenyi Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Matrix Gla protein deficiency causes arteriovenous malformations in mice

(2011) Yucheng Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic DLL4 blockade induces vascular neoplasms

(2010) Minhong Yan et al.   NATURE

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis

(2008) Y. H. Kim et al.   DEVELOPMENT

Disruption of the transcription factor recombination signal-binding protein-Jκ (RBP-J) leads to veno-occlusive disease and interfered liver regeneration in mice

(2008) Lin Wang et al.   HEPATOLOGY

Vascular disorders of the liver

(2008) Laurie D. DeLeve et al.   HEPATOLOGY

Bevacizumab reverses need for liver transplantation in hereditary hemorrhagic telangiectasia

(2008) Andrew Mitchell et al.   LIVER TRANSPLANTATION

Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice

(2008) P. A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA