Pharmacokinetic drug-drug interactions of tyrosine kinase inhibitors: A focus on cytochrome P450, transporters, and acid suppression therapy
出版年份 2016 全文链接
标题
Pharmacokinetic drug-drug interactions of tyrosine kinase inhibitors: A focus on cytochrome P450, transporters, and acid suppression therapy
作者
关键词
-
出版物
HEMATOLOGICAL ONCOLOGY
Volume 35, Issue 3, Pages 259-280
出版商
Wiley
发表日期
2016-12-07
DOI
10.1002/hon.2335
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Life Expectancy of Patients With Chronic Myeloid Leukemia Approaches the Life Expectancy of the General Population
- (2016) Hannah Bower et al. JOURNAL OF CLINICAL ONCOLOGY
- Adverse event potentially due to an interaction between ibrutinib and verapamil: a case report
- (2016) E. Lambert Kuhn et al. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
- Management of adverse events associated with tyrosine kinase inhibitors in chronic myeloid leukemia
- (2015) Delphine Rea ANNALS OF HEMATOLOGY
- Variability in bioavailability of small molecular tyrosine kinase inhibitors
- (2015) Maikel Herbrink et al. CANCER TREATMENT REVIEWS
- Clinical Pharmacokinetic and Pharmacodynamic Profile of Idelalisib
- (2015) Srinivasan Ramanathan et al. CLINICAL PHARMACOKINETICS
- Enzyme- and transporter-mediated beverage-drug interactions: An update on fruit juices and green tea
- (2015) Guohua An et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Ingredients in Fruit Juices Interact with Dasatinib Through Inhibition of BCRP: A New Mechanism of Beverage-Drug Interaction
- (2015) Brett Fleisher et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Genetic Polymorphisms and Function of the Organic Anion-Transporting Polypeptide 1A2 and Its Clinical Relevance in Drug Disposition
- (2015) Yinhui Zhou et al. PHARMACOLOGY
- Impact ofCYP2C8*3polymorphism onin vitrometabolism of imatinib to N-desmethyl imatinib
- (2015) Muhammad Suleman Khan et al. XENOBIOTICA
- Predicting Drug-Drug Interactions Involving Multiple Mechanisms Using Physiologically Based Pharmacokinetic Modeling: A Case Study With Ruxolitinib
- (2015) JG Shi et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update
- (2014) Qingcheng Mao et al. AAPS Journal
- Inhibition of OATP1B1 by tyrosine kinase inhibitors: in vitro–in vivo correlations
- (2014) S Hu et al. BRITISH JOURNAL OF CANCER
- Association of ABCG2 polymorphism with clinical efficacy of imatinib in patients with gastrointestinal stromal tumor
- (2014) Dong-Hoe Koo et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- The effect of rifampicin, a prototypical CYP3A4 inducer, on erlotinib pharmacokinetics in healthy subjects
- (2014) Marta Hamilton et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Oral epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: Comparative pharmacokinetics and drug–drug interactions
- (2014) Solange Peters et al. CANCER TREATMENT REVIEWS
- Pharmacokinetic Drug Interactions of Afatinib with Rifampicin and Ritonavir
- (2014) Sven Wind et al. CLINICAL DRUG INVESTIGATION
- Pharmacokinetic Evaluations of the Co-Administrations of Vandetanib and Metformin, Digoxin, Midazolam, Omeprazole or Ranitidine
- (2014) Susanne Johansson et al. CLINICAL PHARMACOKINETICS
- pH-Dependent Drug–Drug Interactions for Weak Base Drugs: Potential Implications for New Drug Development
- (2014) L Zhang et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Enzyme-Transporter-Mediated Drug Interactions with Small Molecule Tyrosine Kinase Inhibitors
- (2014) Jie Shao et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Drug–drug interactions with tyrosine-kinase inhibitors: a clinical perspective
- (2014) Roelof W F van Leeuwen et al. LANCET ONCOLOGY
- Drug interactions between tyrosine-kinase inhibitors and acid suppressive agents: more than meets the eye
- (2014) Guo Yu et al. LANCET ONCOLOGY
- Determining the optimal dose in the development of anticancer agents
- (2014) Ron H. J. Mathijssen et al. Nature Reviews Clinical Oncology
- ABC Transporters in Multi-Drug Resistance and ADME-Tox of Small Molecule Tyrosine Kinase Inhibitors
- (2014) Jiexin Deng et al. PHARMACEUTICAL RESEARCH
- Sunitinib in combination with clarithromycin or azithromycin – is there a risk of interaction or not?
- (2014) Edyta Szałek et al. Pharmacological Reports
- Pharmacokinetics of sunitinib in combination with fluoroquinolones in rabbit model
- (2014) Edyta Szałek et al. Pharmacological Reports
- Pharmacokinetic Drug Interaction Between Cyclosporine and Imatinib in Bone Marrow Transplant Children and Model-Based Reappraisal of Imatinib Drug Interaction Profile
- (2014) Nathalie Bleyzac et al. THERAPEUTIC DRUG MONITORING
- Crizotinib: A New Treatment Option for ALK-Positive Non-Small Cell Lung Cancer
- (2013) Cindy L O'Bryant et al. ANNALS OF PHARMACOTHERAPY
- Effects of ketoconazole and esomeprazole on the pharmacokinetics of pazopanib in patients with solid tumors
- (2013) Antoinette R. Tan et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Relevance of in vitro and clinical data for predicting CYP3A4-mediated herb–drug interactions in cancer patients
- (2013) Andrew K.L. Goey et al. CANCER TREATMENT REVIEWS
- Gemfibrozil Impairs Imatinib Absorption and Inhibits the CYP2C8-Mediated Formation of Its Main Metabolite
- (2013) A M Filppula et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Drug interactions with solid tumour-targeted therapies
- (2013) Audrey Thomas-Schoemann et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Differential effects of ketoconazole, itraconazole and voriconazole on the pharmacokinetics of imatinib and its main metabolite GCP74588 in rat
- (2013) Gaotong Lin et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Effect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications
- (2013) Rebecca Schnepf et al. Expert Opinion on Drug Metabolism & Toxicology
- Interactions between oral antineoplastic agents and concomitant medication: a systematic review
- (2013) Esther Carcelero et al. Expert Opinion On Drug Safety
- Twelve-Month Frequency of Drug-Metabolizing Enzyme and Transporter-Based Drug-Drug Interaction Potential in Patients Receiving Oral Enzyme-Targeted Kinase Inhibitor Antineoplastic Agents
- (2013) Steven J. Bowlin et al. MAYO CLINIC PROCEEDINGS
- Prevalence of Acid-Reducing Agents (ARA) in Cancer Populations and ARA Drug–Drug Interaction Potential for Molecular Targeted Agents in Clinical Development
- (2013) Gillian S. Smelick et al. MOLECULAR PHARMACEUTICS
- The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation
- (2013) C R S Uppugunduri et al. PHARMACOGENOMICS JOURNAL
- Pharmacokinetic Drug Interactions with Vandetanib during Coadministration with Rifampicin or Itraconazole
- (2013) Paul Martin et al. Drugs in research & development
- Patient adherence to tyrosine kinase inhibitor therapy in chronic myeloid leukemia
- (2012) Elias J. Jabbour et al. AMERICAN JOURNAL OF HEMATOLOGY
- Influence of enzyme and transporter polymorphisms on trough imatinib concentration and clinical response in chronic myeloid leukemia patients
- (2012) S. J. Seong et al. ANNALS OF ONCOLOGY
- Reduced CYP2D6 function is associated with gefitinib-induced rash in patients with non-small cell lung cancer
- (2012) Tomohiro Suzumura et al. BMC CANCER
- Phase I study of lapatinib plus vinorelbine in patients with locally advanced or metastatic breast cancer overexpressing HER2
- (2012) E Brain et al. BRITISH JOURNAL OF CANCER
- Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein
- (2012) Wen-jing Zhou et al. BRITISH JOURNAL OF PHARMACOLOGY
- Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models
- (2012) Amit K. Tiwari et al. CANCER LETTERS
- Drug Absorption Interactions Between Oral Targeted Anticancer Agents and PPIs: Is pH-Dependent Solubility the Achilles Heel of Targeted Therapy?
- (2012) N R Budha et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Ascending Single-Dose Study of the Safety Profile, Tolerability, and Pharmacokinetics of Bosutinib Coadministered With Ketoconazole to Healthy Adult Subjects
- (2012) Richat Abbas et al. CLINICAL THERAPEUTICS
- Co-administration strategy to enhance brain accumulation of vandetanib by modulating P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp1/Abcg2) mediated efflux with m-TOR inhibitors
- (2012) Mukul Minocha et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Nilotinib Counteracts P-Glycoprotein-Mediated Multidrug Resistance and Synergizes the Antitumoral Effect of Doxorubicin in Soft Tissue Sarcomas
- (2012) Victor Hugo Villar et al. PLoS One
- Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors
- (2011) Yong Liu et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Interaction of innovative small molecule drugs used for cancer therapy with drug transporters
- (2011) K Mandery et al. BRITISH JOURNAL OF PHARMACOLOGY
- Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study
- (2011) Keith T. Flaherty et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Two Drug Interaction Studies of Sirolimus in Combination with Sorafenib or Sunitinib in Patients with Advanced Malignancies
- (2011) T. C. Gangadhar et al. CLINICAL CANCER RESEARCH
- Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors
- (2011) Paola Di Gion et al. CLINICAL PHARMACOKINETICS
- The effect of grapefruit juice on drug disposition
- (2011) Michael J Hanley et al. Expert Opinion on Drug Metabolism & Toxicology
- How Many Cancer Patients Use Complementary and Alternative Medicine
- (2011) Markus Horneber et al. INTEGRATIVE CANCER THERAPIES
- The Effect of CYP3A4 Inhibition or Induction on the Pharmacokinetics and Pharmacodynamics of Orally Administered Ruxolitinib (INCB018424 Phosphate) in Healthy Volunteers
- (2011) Jack G. Shi et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study
- (2011) Jesus Garcia-Donas et al. LANCET ONCOLOGY
- Polypharmacy in elderly patients with cancer: clinical implications and management
- (2011) Judith Lees et al. LANCET ONCOLOGY
- Drug-Induced Effects on Erlotinib Metabolism
- (2011) Olivier Mir et al. NEW ENGLAND JOURNAL OF MEDICINE
- Elevated International Normalized Ratio associated with concomitant warfarin and erlotinib
- (2010) K. S. Thomas et al. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
- Imatinib and Panax Ginseng: A Potential Interaction Resulting in Liver Toxicity
- (2010) Naveen Bilgi et al. ANNALS OF PHARMACOTHERAPY
- Fruit juice inhibition of uptake transport: a new type of food-drug interaction
- (2010) David G. Bailey BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors
- (2010) Faye M. Johnson et al. CANCER
- Effects of Nilotinib on Single-Dose Warfarin Pharmacokinetics and Pharmacodynamics
- (2010) Ophelia Q.P. Yin et al. CLINICAL DRUG INVESTIGATION
- Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma
- (2010) Charline Gomo et al. INVESTIGATIONAL NEW DRUGS
- Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers
- (2010) Yazdi K. Pithavala et al. INVESTIGATIONAL NEW DRUGS
- Effects of Rifampin and Ketoconazole on the Pharmacokinetics of Nilotinib in Healthy Participants
- (2010) Chiaki Tanaka et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma
- (2010) David A. Reardon et al. JOURNAL OF NEURO-ONCOLOGY
- Potential for drug–drug interactions in treating cancer-related nausea and distress
- (2010) Matthew S Saylor et al. JOURNAL OF ONCOLOGY PHARMACY PRACTICE
- Effects of ketoconazole and carbamazepine on lapatinib pharmacokinetics in healthy subjects
- (2009) Deborah A. Smith et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Gefitinib-phenytoin interaction is not correlated with the14C-erythromycin breath test in healthy male volunteers
- (2009) Stephanie Chhun et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Effect of rifampin on the pharmacokinetics of Axitinib (AG-013736) in Japanese and Caucasian healthy volunteers
- (2009) Y. K. Pithavala et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Clinical pharmacokinetics of tyrosine kinase inhibitors
- (2009) Nielka P. van Erp et al. CANCER TREATMENT REVIEWS
- Sorafenib
- (2009) Gillian M. Keating et al. DRUGS
- Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034
- (2009) Martin J. van den Bent et al. JOURNAL OF CLINICAL ONCOLOGY
- Mécanismes des interactions médicamenteuses d’origine pharmacocinétique
- (2009) D. Levêque et al. REVUE DE MEDECINE INTERNE
- Evaluation of Lapatinib and Topotecan Combination Therapy: Tissue Culture, Murine Xenograft, and Phase I Clinical Trial Data
- (2008) J. R. Molina et al. CLINICAL CANCER RESEARCH
- Rhabdomyolysis Resulting from Pharmacologic Interaction Between Erlotinib and Simvastatin
- (2008) Muthu Veeraputhiran et al. Clinical Lung Cancer
- Drug–Drug Interactions Mediated Through P-Glycoprotein: Clinical Relevance and In Vitro–In Vivo Correlation Using Digoxin as a Probe Drug
- (2008) KS Fenner et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Valproic acid enhances bosutinib cytotoxicity in colon cancer cells
- (2008) Luca Mologni et al. INTERNATIONAL JOURNAL OF CANCER
- Modulation of the antitumor activity of metronomic cyclophosphamide by the angiogenesis inhibitor axitinib
- (2008) J. Ma et al. MOLECULAR CANCER THERAPEUTICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now