Natural Products, Alone or in Combination with FDA-Approved Drugs, to Treat COVID-19 and Lung Cancer
出版年份 2021 全文链接
标题
Natural Products, Alone or in Combination with FDA-Approved Drugs, to Treat COVID-19 and Lung Cancer
作者
关键词
-
出版物
Biomedicines
Volume 9, Issue 6, Pages 689
出版商
MDPI AG
发表日期
2021-06-18
DOI
10.3390/biomedicines9060689
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cancer Statistics, 2021
- (2021) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor
- (2021) Sarah O'Keefe et al. JOURNAL OF CELL SCIENCE
- Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro
- (2021) Hongbo Liu et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Chinese herbal medicine: Fighting SARS-CoV-2 infection on all fronts
- (2021) Zhonglei Wang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
- (2021) Jia-Tsrong Jan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ERK Activation-Mediated Autophagy Induction Resists Licochalcone A-Induced Anticancer Activities in Lung Cancer Cells in vitro
- (2021) Wei Luo et al. OncoTargets and Therapy
- Gracillin Isolated from Reineckia carnea Induces Apoptosis of A549 Cells via the Mitochondrial Pathway
- (2021) Jianqiong Yang et al. Drug Design Development and Therapy
- An Integrated Strategy for Effective-Component Discovery of Astragali Radix in the Treatment of Lung Cancer
- (2021) Bing Yang et al. Frontiers in Pharmacology
- Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E
- (2021) Ram Kumar et al. ANTIVIRAL RESEARCH
- Vincamine, a safe natural alkaloid, represents a novel anticancer agent
- (2021) Sarah Al-Rashed et al. BIOORGANIC CHEMISTRY
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Remdesivir Metabolite GS-441524 Effectively Inhibits SARS-CoV-2 Infection in Mouse Models
- (2021) Yingjun Li et al. JOURNAL OF MEDICINAL CHEMISTRY
- Antiviral Bafilomycins from a Feces-Inhabiting Streptomyces sp.
- (2021) Xi Xie et al. JOURNAL OF NATURAL PRODUCTS
- Axial Chiral Binaphthoquinone and Perylenequinones from the Stromata of Hypocrella bambusae Are SARS-CoV-2 Entry Inhibitors
- (2021) Yu-Ting Li et al. JOURNAL OF NATURAL PRODUCTS
- Kobophenol A Inhibits Binding of Host ACE2 Receptor with Spike RBD Domain of SARS-CoV-2, a Lead Compound for Blocking COVID-19
- (2021) Suresh Gangadevi et al. Journal of Physical Chemistry Letters
- The need for precision nutrition, genetic variation and resolution in Covid-19 patients
- (2021) Artemis P. Simopoulos et al. MOLECULAR ASPECTS OF MEDICINE
- Natural products in drug discovery: advances and opportunities
- (2021) Atanas G. Atanasov et al. NATURE REVIEWS DRUG DISCOVERY
- SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model
- (2021) Jingxin Qiao et al. SCIENCE
- Quercetin induces pro‐apoptotic autophagy via SIRT1 / AMPK signaling pathway in human lung cancer cell lines A549 and H1299 in vitro
- (2021) Hengjuan Guo et al. Thoracic Cancer
- Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases
- (2021) Zinuo Chen et al. Cell and Bioscience
- Perspectives and controversies regarding the use of natural products for the treatment of lung cancer
- (2021) Tingting Wen et al. Cancer Medicine
- Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase
- (2021) Quanjie Li et al. Acta Pharmaceutica Sinica B
- Toxicarioside O Inhibits Cell Proliferation and Epithelial-Mesenchymal Transition by Downregulation of Trop2 in Lung Cancer Cells
- (2021) Wu-Ping Zheng et al. Frontiers in Oncology
- Parthenolide Augments the Chemosensitivity of Non-small-Cell Lung Cancer to Cisplatin via the PI3K/AKT Signaling Pathway
- (2021) Li-Mei Wu et al. Frontiers in Cell and Developmental Biology
- Baicalin Induces Apoptosis and Suppresses the Cell Cycle Progression of Lung Cancer Cells Through Downregulating Akt/mTOR Signaling Pathway
- (2021) Xinbing Sui et al. Frontiers in Molecular Biosciences
- Repurposing of Some Natural Product Isolates as SARS-COV-2 Main Protease Inhibitors via In Vitro Cell Free and Cell-Based Antiviral Assessments and Molecular Modeling Approaches
- (2021) Hossam M. Abdallah et al. Pharmaceuticals
- Active ingredients from Chinese medicine plants as therapeutic strategies for asthma: Overview and challenges
- (2021) Wenqian Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- A grafted peptidomimetic for EGFR heterodimerization inhibition: Implications in NSCLC models
- (2021) Sitanshu S. Singh et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Epigallocatechin-3-gallate, an active ingredient of Traditional Chinese Medicines, inhibits the 3CLpro activity of SARS-CoV-2
- (2021) Ashuai Du et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Anti-SARS-CoV-2 Activity of Andrographis paniculata Extract and Its Major Component Andrographolide in Human Lung Epithelial Cells and Cytotoxicity Evaluation in Major Organ Cell Representatives
- (2021) Khanit Sa-ngiamsuntorn et al. JOURNAL OF NATURAL PRODUCTS
- Post-acute COVID-19 syndrome
- (2021) Ani Nalbandian et al. NATURE MEDICINE
- Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
- (2021) Hardeep Singh Tuli et al. PHARMACOLOGICAL RESEARCH
- Polyphyllin I reverses the resistance of osimertinib in non-small cell lung cancer cell through regulation of PI3K/Akt signaling
- (2021) Lei Lai et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Erianthridin suppresses non-small-cell lung cancer cell metastasis through inhibition of Akt/mTOR/p70S6K signaling pathway
- (2021) Sutthaorn Pothongsrisit et al. Scientific Reports
- The Cardenolide Glycoside Acovenoside A Interferes with Epidermal Growth Factor Receptor Trafficking in Non-Small Cell Lung Cancer Cells
- (2021) Susanne Hafner et al. Frontiers in Pharmacology
- Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase
- (2021) Keivan Zandi et al. Microorganisms
- Discovery of chebulagic acid and punicalagin as novel allosteric inhibitors of SARS-CoV-2 3CLpro
- (2021) Ruikun Du et al. ANTIVIRAL RESEARCH
- Novel inhibitors of the main protease enzyme of SARS-CoV-2 identified via molecular dynamics simulation-guided in vitro assay
- (2021) Jennifer Loschwitz et al. BIOORGANIC CHEMISTRY
- Epigallocatechin Gallate Inhibits the Uridylate-Specific Endoribonuclease Nsp15 and Efficiently Neutralizes the SARS-CoV-2 Strain
- (2021) Seokho Hong et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Rutin and flavone analogs as prospective SARS-CoV-2 main protease inhibitors: In silico drug discovery study
- (2021) Mahmoud A.A. Ibrahim et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms
- (2021) Kai Huang et al. PHARMACOLOGY & THERAPEUTICS
- Artemether, Artesunate, Arteannuin B, Echinatin, Licochalcone B and Andrographolide Effectively Inhibit SARS-CoV-2 and Related Viruses In Vitro
- (2021) Yunjia Hu et al. Frontiers in Cellular and Infection Microbiology
- Myricetin Inhibits SARS-CoV-2 Viral Replication by Targeting Mpro and Ameliorates Pulmonary Inflammation
- (2021) Ting Xiao et al. Frontiers in Pharmacology
- Tutuilamides A–C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties
- (2020) Lena Keller et al. ACS Chemical Biology
- Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity
- (2020) Le-le Zhang et al. ACTA PHARMACOLOGICA SINICA
- Polyphyllin I activates AMPK to suppress the growth of non-small-cell lung cancer via induction of autophagy
- (2020) Yezi Wu et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
- (2020) Manli Wang et al. CELL RESEARCH
- EGCG regulates CTR1 expression through its pro‐oxidative property in non‐small‐cell lung cancer cells
- (2020) Aochang Chen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Clerodane Diterpenoids Isolated from the Leaves of Casearia graveolens
- (2020) Feng Liu et al. JOURNAL OF NATURAL PRODUCTS
- A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
- (2020) Jasper Fuk-Woo Chan et al. LANCET
- A novel coronavirus outbreak of global health concern
- (2020) Chen Wang et al. LANCET
- PDB-1 from Potentilla discolor Bunge suppresses lung cancer cell migration and invasion via FAK/Src and MAPK signaling pathways
- (2020) Na-na Meng et al. MEDICINAL CHEMISTRY RESEARCH
- Overcoming acquired resistance of EGFR‐mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib, with the natural product honokiol
- (2020) Hongjing Zang et al. Molecular Oncology
- Casticin Induces DNA Damage and Affects DNA Repair Associated Protein Expression in Human Lung Cancer A549 Cells (Running Title: Casticin Induces DNA Damage in Lung Cancer Cells)
- (2020) Zheng-Yu Cheng et al. MOLECULES
- Importation and Human-to-Human Transmission of a Novel Coronavirus in Vietnam
- (2020) Lan T. Phan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting defective pulmonary innate immunity – A new therapeutic option?
- (2020) Kylie B.R. Belchamber et al. PHARMACOLOGY & THERAPEUTICS
- Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
- (2020) Emmie de Wit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deguelin suppresses non-small cell lung cancer by inhibiting EGFR signaling and promoting GSK3β/FBW7-mediated Mcl-1 destabilization
- (2020) Feng Gao et al. Cell Death & Disease
- Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
- (2020) Timothy P. Sheahan et al. Nature Communications
- Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
- (2020) Sangeun Jeon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Sinomenine Inhibits Migration and Invasion of Human Lung Cancer Cell through Downregulating Expression of miR-21 and MMPs
- (2020) Kun-Hung Shen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Formononetin inhibits tumor growth by suppression of EGFR-Akt-Mcl-1 axis in non-small cell lung cancer
- (2020) Xinyou Yu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The anti‐HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell fusion caused by the SARSCoV‐2 spike (S) glycoprotein warranting further evaluation as an antiviral against COVID‐19 infections
- (2020) Farhana Musarrat et al. JOURNAL OF MEDICAL VIROLOGY
- Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
- (2020) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs
- (2020) Chung-Pu Wu et al. JOURNAL OF NATURAL PRODUCTS
- Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
- (2020) Yeming Wang et al. LANCET
- Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
- (2020) Zhenming Jin et al. NATURE
- The small-cell lung cancer drug market
- (2020) Joshua B. N. Dawkins et al. NATURE REVIEWS DRUG DISCOVERY
- Hispidulin exhibits potent anticancer activity in�vitro and in�vivo through activating ER stress in non‑small‑cell lung cancer cells
- (2020) Li Lv et al. ONCOLOGY REPORTS
- Licochalcone A reverses NNK-induced ectopic miRNA expression to elicit in vitro and in vivo chemopreventive effects
- (2020) Bingxin Li et al. PHYTOMEDICINE
- Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
- (2020) Wanchao Yin et al. SCIENCE
- Sinomenine Inhibits Non-Small Cell Lung Cancer via Downregulation of Hexokinases II-Mediated Aerobic Glycolysis
- (2020) Wenbin Liu et al. OncoTargets and Therapy
- TMPRSS2 and COVID-19: Serendipity or Opportunity for Intervention?
- (2020) Konrad H. Stopsack et al. Cancer Discovery
- Gallic Acid Impedes Non-Small Cell Lung Cancer Progression via Suppression of EGFR-Dependent CARM1-PELP1 Complex
- (2020) Dong Wang et al. Drug Design Development and Therapy
- Effects of wogonoside on invasion and migration of lung cancer A549 cells and angiogenesis in xenograft tumors of nude mice
- (2020) Yubo Yan et al. Journal of Thoracic Disease
- The Inhibitory Mechanisms of Tumor PD-L1 Expression by Natural Bioactive Gallic Acid in Non-Small-Cell Lung Cancer (NSCLC) Cells
- (2020) Dong Young Kang et al. Cancers
- Potent Anticancer Effect of the Natural Steroidal Saponin Gracillin Is Produced by Inhibiting Glycolysis and Oxidative Phosphorylation-Mediated Bioenergetics
- (2020) Hye-Young Min et al. Cancers
- Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
- (2020) Hai-xia Su et al. ACTA PHARMACOLOGICA SINICA
- Icaritin inhibits lung cancer-induced osteoclastogenesis by suppressing the expression of IL-6 and TNF-a and through AMPK/mTOR signaling pathway
- (2020) Xueqiang Zhao et al. ANTI-CANCER DRUGS
- Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro
- (2020) Ka-Tim Choy et al. ANTIVIRAL RESEARCH
- Baicalein inhibits NSCLC invasion and metastasis by reducing ezrin tension in inflammation microenvironment
- (2020) Xiaolong Zhang et al. CANCER SCIENCE
- Ring finger protein 38 induces the drug resistance of cisplatin in non‐small cell lung cancer
- (2020) Chao Wu et al. CELL BIOLOGY INTERNATIONAL
- Silibinin suppresses epithelial–mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1
- (2020) Suyan Xu et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Liriopesides B induces apoptosis and cell cycle arrest in human non‑small cell lung cancer cells
- (2020) Hongxu Sheng et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Dioscin elicits anti‐tumour immunity by inhibiting macrophage M2 polarization via JNK and STAT3 pathways in lung cancer
- (2020) Luyun Cui et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Versatile role of curcumin and its derivatives in lung cancer therapy
- (2020) Milad Ashrafizadeh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Inhibitory effect of sinomenine on lung cancer cells via negative regulation of α7 nicotinic acetylcholine receptor
- (2020) Shasha Bai et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Enhanced solubility, stability, permeation and anti-cancer efficacy of Celastrol-β-cyclodextrin inclusion complex
- (2020) Snehal K. Shukla et al. JOURNAL OF MOLECULAR LIQUIDS
- Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2
- (2020) Brandi N. Williamson et al. NATURE
- Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
- (2020) Donghyuk Shin et al. NATURE
- Parthenolide inhibits human lung cancer cell growth by modulating the IGF‑1R/PI3K/Akt signaling pathway
- (2020) Longhua Sun et al. ONCOLOGY REPORTS
- Xanthohumol targets the ERK1/2‑Fra1 signaling axis to reduce cyclin D1 expression and inhibit non‑small cell lung cancer
- (2020) Feng Gao et al. ONCOLOGY REPORTS
- The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization
- (2020) Min Zha et al. Cell Death & Disease
- Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment
- (2020) Victoria C. Yan et al. ACS Medicinal Chemistry Letters
- In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication
- (2020) Franck Touret et al. Scientific Reports
- Turning the Tide: Natural Products and Natural-Product-Inspired Chemicals as Potential Counters to SARS-CoV-2 Infection
- (2020) Zhonglei Wang et al. Frontiers in Pharmacology
- Anti-SARS-CoV-2 Potential of Artemisinins In Vitro
- (2020) Ruiyuan Cao et al. ACS Infectious Diseases
- Molecular Mechanisms of Cardiomyocyte Death in Drug-Induced Cardiotoxicity
- (2020) Wanjun Ma et al. Frontiers in Cell and Developmental Biology
- Engineering EHD1-Targeted Natural Borneol Nanoemulsion Potentiates Therapeutic Efficacy of Gefitinib against Nonsmall Lung Cancer
- (2020) Riming Yuan et al. ACS Applied Materials & Interfaces
- EGCG sensitizes chemotherapeutic-induced cytotoxicity by targeting the ERK pathway in multiple cancer cell lines
- (2020) Ran Wei et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Direct targeting of HSP90 with daurisoline destabilizes β-catenin to suppress lung cancer tumorigenesis
- (2020) Xiao-Hui Huang et al. CANCER LETTERS
- β-Cyclodextrin-modified hyaluronic acid-based supramolecular self-assemblies for pH- and esterase- dual-responsive drug delivery
- (2020) Yang Bai et al. CARBOHYDRATE POLYMERS
- Tumor-specific carrier-free nanodrugs with GSH depletion and enhanced ROS generation for endogenous synergistic anti-tumor by a chemotherapy-photodynamic therapy
- (2020) Jin-Shuai Lan et al. CHEMICAL ENGINEERING JOURNAL
- Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase
- (2020) Lin Cao et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Triterpenoids from the Leaves of Centella asiatica Inhibit Ionizing Radiation-Induced Migration and Invasion of Human Lung Cancer Cells
- (2020) Ah-Reum Han et al. Evidence-based Complementary and Alternative Medicine
- Tea Polyphenols EGCG and Theaflavin Inhibit the Activity of SARS-CoV-2 3CL-Protease In Vitro
- (2020) Minsu Jang et al. Evidence-based Complementary and Alternative Medicine
- Glochidiol, a natural triterpenoid, exerts its anti-cancer effects by targeting the colchicine binding site of tubulin
- (2020) Hongjie Chen et al. INVESTIGATIONAL NEW DRUGS
- Efficacy of Remdesivir in COVID-19
- (2020) Erin K. McCreary et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- COVID-19: discovery, diagnostics and drug development
- (2020) Tarik Asselah et al. JOURNAL OF HEPATOLOGY
- Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
- (2020) Namrta Choudhry et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural and therapeutic properties of curcumin solubilized pluronic F127 micellar solutions and hydrogels
- (2020) R. Ganguly et al. JOURNAL OF MOLECULAR LIQUIDS
- Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion
- (2020) Donald J. Benton et al. NATURE
- Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms
- (2020) Yu-Qiong He et al. PHARMACOLOGICAL RESEARCH
- NARINGENIN IS A POWERFUL INHIBITOR OF SARS-CoV-2 INFECTION IN VITRO
- (2020) Nicola Clementi et al. PHARMACOLOGICAL RESEARCH
- Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells
- (2020) Luo-Wei Yuan et al. PHYTOMEDICINE
- Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein
- (2020) Christine Toelzer et al. SCIENCE
- An Activatable Nano‐Prodrug for Treating Tyrosine‐Kinase‐Inhibitor‐Resistant Non‐Small Cell Lung Cancer and for Optoacoustic and Fluorescent Imaging
- (2020) Xin Xie et al. Small
- Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3
- (2020) Xin Liu et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Anti-SARS-CoV Natural Products With the Potential to Inhibit SARS-CoV-2 (COVID-19)
- (2020) Surjeet Verma et al. Frontiers in Pharmacology
- Fatal toxic effects related to EGFR tyrosine kinase inhibitors based on 53 cohorts with 9,569 participants
- (2020) Xianhe Xie et al. Journal of Thoracic Disease
- Kaempferol inhibits Nrf2 signalling pathway via downregulation of Nrf2 mRNA and induces apoptosis in NSCLC cells
- (2020) Chandrani Fouzder et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro
- (2020) Junke Song et al. BIOCHEMICAL PHARMACOLOGY
- Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3
- (2020) Jian Li et al. BIOMEDICINE & PHARMACOTHERAPY
- Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7
- (2020) Qi-Yin Chen et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Transcriptome analysis of cepharanthine against a SARS-CoV-2-related coronavirus
- (2020) Shasha Li et al. BRIEFINGS IN BIOINFORMATICS
- Parthenolide inhibits the growth of non-small cell lung cancer by targeting epidermal growth factor receptor
- (2020) Xiaoling Li et al. Cancer Cell International
- Comparison of Redox Responsiveness and Antitumor Capability of Paclitaxel Dimeric Nanoparticles with Different Linkers
- (2020) Jian Wang et al. CHEMISTRY OF MATERIALS
- Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies
- (2020) Pooja M et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Assessment of antiviral potencies of cannabinoids against SARS-CoV-2 using computational and in vitro approaches
- (2020) Vinit Raj et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Licochalcone A inhibits EGFR signalling and translationally suppresses survivin expression in human cancer cells
- (2020) Feng Gao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Celastrol acts synergistically with afatinib to suppress non‐small cell lung cancer cell proliferation by inducing paraptosis
- (2020) Chun‐Hau Dai et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2
- (2020) Mitchell P. Christy et al. JOURNAL OF NATURAL PRODUCTS
- FDA Approval of Remdesivir — A Step in the Right Direction
- (2020) Daniel Rubin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Resveratrol inhibits the replication of severe acute respiratory syndrome coronavirus 2 ( SARS‐CoV ‐2) in cultured Vero cells
- (2020) Minghui Yang et al. PHYTOTHERAPY RESEARCH
- Erianthridin Induces Non-small Cell Lung Cancer Cell Apoptosis through the Suppression of Extracellular Signal-regulated Kinase Activity
- (2020) Sirima Boonjing et al. PLANTA MEDICA
- A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection
- (2020) Peng Wang et al. Cell Death & Disease
- Remdesivir: a pendulum in a pandemic
- (2020) Ilan S Schwartz et al. BMJ-British Medical Journal
- ACE2: the molecular doorway to SARS-CoV-2
- (2020) Miriam Marlene Medina-Enríquez et al. Cell and Bioscience
- Docking Characterization and in vitro Inhibitory Activity of Flavan-3-ols and Dimeric Proanthocyanidins Against the Main Protease Activity of SARS-Cov-2
- (2020) Yue Zhu et al. Frontiers in Plant Science
- Pure redox-sensitive paclitaxel–maleimide prodrug nanoparticles: Endogenous albumin-induced size switching and improved antitumor efficiency
- (2020) Xinyu Lou et al. Acta Pharmaceutica Sinica B
- Self-Assembled Disulfide Bond Bearing Paclitaxel—Camptothecin Prodrug Nanoparticle for Lung Cancer Therapy
- (2020) Jingyan Gao et al. Pharmaceutics
- Exogenous hormone on episperm development and ginkgolic acid accumulation in Ginkgo biloba L
- (2020) Junru Yang et al. INDUSTRIAL CROPS AND PRODUCTS
- Targeted delivery of quercetin by nanoparticles based on chitosan sensitizing paclitaxel-resistant lung cancer cells to paclitaxel
- (2020) Yonghong Wang et al. Materials Science & Engineering C-Materials for Biological Applications
- Crosstalk between alveolar macrophages and alveolar epithelial cells/fibroblasts contributes to the pulmonary toxicity of gefitinib
- (2020) Jiangxia Du et al. TOXICOLOGY LETTERS
- Anti-esophageal Cancer Effect of Corilagin Extracted from Phmllanthi Fructus via the Mitochondrial and Endoplasmic Reticulum Stress Pathways
- (2020) Chaoqun Wu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Erianin regulates programmed cell death ligand 1 expression and enhances cytotoxic T lymphocyte activity
- (2020) Ao Yang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication
- (2019) Bingpeng Yan et al. Viruses-Basel
- Axl is a novel target of celastrol that inhibits cell proliferation and migration, and increases the cytotoxicity of gefitinib in EGFR mutant non‑small cell lung cancer cells
- (2019) Youn Lee et al. Molecular Medicine Reports
- Fluorescent probe for sensitive discrimination of Hcy and Cys/GSH in living cells via dual-emission
- (2019) Shuang Xu et al. ANALYTICA CHIMICA ACTA
- Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge
- (2019) Michael K. Lo et al. Science Translational Medicine
- Cisplatin: The first metal based anticancer drug
- (2019) Sumit Ghosh BIOORGANIC CHEMISTRY
- Characterisation of infectious Ebola virus from the ongoing outbreak to guide response activities in the Democratic Republic of the Congo: a phylogenetic and in vitro analysis
- (2019) Laura K McMullan et al. LANCET INFECTIOUS DISEASES
- Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
- (2019) Christian Bailly PHYTOMEDICINE
- Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells
- (2019) Kim et al. Biomolecules
- Microbiome in Chronic Obstructive Pulmonary Disease: Role of Natural Products Against Microbial Pathogens
- (2019) Alessia Santoro et al. CURRENT MEDICINAL CHEMISTRY
- Best practice in research – Overcoming common challenges in phytopharmacological research
- (2019) Michael Heinrich et al. JOURNAL OF ETHNOPHARMACOLOGY
- Celastrol improves the therapeutic efficacy of EGFR-TKIs for non-small-cell lung cancer by overcoming EGFR T790M drug resistance
- (2018) Ying Wang et al. ANTI-CANCER DRUGS
- Progress in the Development of Preventative Drugs for Cisplatin-Induced Hearing Loss
- (2018) Robert A. Hazlitt et al. JOURNAL OF MEDICINAL CHEMISTRY
- Curcumin enhances cisplatin sensitivity of human NSCLC cell lines through influencing Cu-Sp1-CTR1 regulatory loop
- (2018) Wei Zhang et al. PHYTOMEDICINE
- Impact of curcumin nanoformulation on its antimicrobial activity
- (2018) Anderson Clayton da Silva et al. TRENDS IN FOOD SCIENCE & TECHNOLOGY
- Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer
- (2018) Lu Zhang et al. Autophagy
- Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species
- (2018) Uddin Nazim et al. Molecular Medicine Reports
- Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
- (2017) Timothy P. Sheahan et al. Science Translational Medicine
- Late Ebola virus relapse causing meningoencephalitis: a case report
- (2016) Michael Jacobs et al. LANCET
- Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
- (2016) Travis K. Warren et al. NATURE
- Control of autoimmune inflammation by celastrol, a natural triterpenoid
- (2016) Shivaprasad H. Venkatesha et al. Pathogens and Disease
- Chemistry: Chemical con artists foil drug discovery
- (2014) Jonathan Baell et al. NATURE
- Targeted Polysaccharide Nanoparticle for Adamplatin Prodrug Delivery
- (2013) Yang Yang et al. JOURNAL OF MEDICINAL CHEMISTRY
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