The relationship between cytokine and neutrophil gene network distinguishes SARS-CoV-2–infected patients by sex and age

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

U1 snRNP regulates cancer cell migration and invasion in vitro

(2020) Jung-Min Oh et al.   Nature Communications

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients

(2020) Zhuo Zhou et al.   Cell Host & Microbe

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Cytokine release syndrome in severe COVID-19

(2020) John B. Moore et al.   SCIENCE

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2)

(2020) Ruiyun Li et al.   SCIENCE

COVID-19 and smoking: A systematic review of the evidence

(2020) Constantine Vardavas et al.   Tobacco Induced Diseases

COVID-19 cytokine storm: the interplay between inflammation and coagulation

(2020) Ricardo J Jose et al.   Lancet Respiratory Medicine

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

(2020) Jonas Schulte-Schrepping et al.   CELL

Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19

(2020) Aymeric Silvin et al.   CELL

Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

(2020) Chiara Agrati et al.   CELL DEATH AND DIFFERENTIATION

Blocking inflammation on the way: Rationale for CXCR2 antagonists for the treatment of COVID-19

(2020) Lars M. Koenig et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sex differential in COVID-19 mortality varies markedly by age

(2020) Sunil S Bhopal et al.   LANCET

Clinical and virological data of the first cases of COVID-19 in Europe: a case series

(2020) Francois-Xavier Lescure et al.   LANCET INFECTIOUS DISEASES

COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

(2020) Robert Lorenz Chua et al.   NATURE BIOTECHNOLOGY

Genomewide Association Study of Severe Covid-19 with Respiratory Failure

(2020) David Ellinghaus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Type III interferons disrupt the lung epithelial barrier upon viral recognition

(2020) Achille Broggi et al.   SCIENCE

Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma

(2020) Nathan D. Jackson et al.   Cell Reports

Neutrophil extracellular traps in COVID-19

(2020) Yu Zuo et al.   JCI Insight

ACE2 expression and sex disparity in COVID-19

(2020) Maria Cristina Gagliardi et al.   Cell Death Discovery

Sex differences in immune responses that underlie COVID-19 disease outcomes

(2020) Takehiro Takahashi et al.   NATURE

In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age

(2020) Nicole A. P. Lieberman et al.   PLOS BIOLOGY

Large-Scale Multi-omic Analysis of COVID-19 Severity

(2020) Katherine A. Overmyer et al.   Cell Systems

A whitening approach to probabilistic canonical correlation analysis for omics data integration

(2019) Takoua Jendoubi et al.   BMC BIOINFORMATICS

S100A8 & S100A9: Alarmin mediated inflammation in tendinopathy

(2019) Lindsay A. N. Crowe et al.   Scientific Reports

NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis

(2019) Guangyan Zhou et al.   NUCLEIC ACIDS RESEARCH

Statistical predictions with glmnet

(2019) Solveig Engebretsen et al.   Clinical Epigenetics

CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses

(2018) Pedro S. T. Russo et al.   BMC BIOINFORMATICS

Neutrophils in viral infection

(2018) Victor Naumenko et al.   CELL AND TISSUE RESEARCH

Bootstrapping for multivariate linear regression models

(2018) Daniel J. Eck   STATISTICS & PROBABILITY LETTERS

IID 2018 update: context-specific physical protein–protein interactions in human, model organisms and domesticated species

(2018) Max Kotlyar et al.   NUCLEIC ACIDS RESEARCH

Platelet α-granules modulate the inflammatory response under systemic lipopolysaccharide injection in mice

(2018) Sofiane Tariket et al.   TRANSFUSION

Protecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny

(2017) Tobias R. Kollmann et al.   IMMUNITY

NBEAL2 is required for neutrophil and NK cell function and pathogen defense

(2017) John M. Sowerby et al.   JOURNAL OF CLINICAL INVESTIGATION

Nonparametric Inference for Multivariate Data: The R Package npmv

(2017) Woodrow W. Burchett et al.   Journal of Statistical Software

Data analytics using canonical correlation analysis and Monte Carlo simulation

(2017) Jeffrey M. Rickman et al.   npj Computational Materials

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Neutrophils in viral infections: Current concepts and caveats

(2015) I. E. Galani et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Transcriptional regulation of myeloid-derived suppressor cells

(2015) Thomas Condamine et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Morpheus: a user-friendly modeling environment for multiscale and multicellular systems biology

(2014) Jörn Starruß et al.   BIOINFORMATICS

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response

(2013) Karin Fink et al.   CELL RESEARCH

Neutrophils: Neglected Players in Viral Diseases

(2013) Christelle Gabriel et al.   DNA AND CELL BIOLOGY

Neutrophils are needed for an effective immune response against pulmonary rat coronavirus infection, but also contribute to pathology

(2013) A. K. Haick et al.   JOURNAL OF GENERAL VIROLOGY

Acting locally: innate mucosal immunity in resistance to HIV-1 infection in Kenyan commercial sex workers

(2013) X-D Yao et al.   Mucosal Immunology

Immune Quiescence: a model of protection against HIV infection

(2013) Catherine M Card et al.   Retrovirology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection

(2011) Bisweswar Nandi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HIV‐Exposed Seronegative Commercial Sex Workers Show a Quiescent Phenotype in the CD4+T Cell Compartment and Reduced Expression of HIV‐Dependent Host Factors

(2010) Paul J. McLaren et al.   JOURNAL OF INFECTIOUS DISEASES

Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function

(2010) Thomas Condamine et al.   TRENDS IN IMMUNOLOGY

NAViGaTOR: Network Analysis, Visualization and Graphing Toronto

(2009) Kevin R. Brown et al.   BIOINFORMATICS

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Foxj1 transcription factors are master regulators of the motile ciliogenic program

(2008) Xianwen Yu et al.   NATURE GENETICS