Linking Oxidative Stress and DNA Damage to Changes in the Expression of Extracellular Matrix Components

STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway

(2021) Qiang Guo et al.   Cell Death & Disease

Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress

(2020) Miranda D. Grounds et al.   Disease Models & Mechanisms

Implications of Skeletal Muscle Extracellular Matrix Remodeling in Metabolic Disorders: Diabetes Perspective

(2020) Khurshid Ahmad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidants Reduce Muscular Dystrophy in the dy2J/dy2J Mouse Model of Laminin α2 Chain-Deficient Muscular Dystrophy

(2020) Vahid M. Harandi et al.   Antioxidants

Upregulation of fibronectin following loss of p53 function is a poor prognostic factor in ovarian carcinoma with a unique immunophenotype

(2020) Ako Yokoi et al.   Cell Communication and Signaling

NRF2, a Transcription Factor for Stress Response and Beyond

(2020) Feng He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice

(2020) Timothy M. Moore et al.   Frontiers in Physiology

Lysyl Oxidase (LOX): Functional Contributions to Signaling Pathways

(2020) Rozalia Laczko et al.   Biomolecules

Concepts of extracellular matrix remodelling in tumour progression and metastasis

(2020) Juliane Winkler et al.   Nature Communications

Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents

(2020) Min Deng et al.   Science Advances

The Impact of Mitochondrial Deficiencies in Neuromuscular Diseases

(2020) Judith Cantó-Santos et al.   Antioxidants

Mitochondrial dysfunction in fibrotic diseases

(2020) Xinyu Li et al.   Cell Death Discovery

BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy

(2020) Marco Segatto et al.   Nature Communications

Dystrophin Deficiency Leads to Genomic Instability in Human Pluripotent Stem Cells via NO Synthase-Induced Oxidative Stress

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Compromised Exercise Capacity and Mitochondrial Dysfunction in the Osteogenesis Imperfecta Murine (oim ) Mouse Model

(2019) Victoria L Gremminger et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mechanosensing by the Lamina Protects against Nuclear Rupture, DNA Damage, and Cell-Cycle Arrest

(2019) Sangkyun Cho et al.   DEVELOPMENTAL CELL

Identification of Candidate Protein Markers in Skeletal Muscle of Laminin-211-Deficient CMD Type 1A-Patients

(2019) Heike Kölbel et al.   Frontiers in Neurology

Cell Adhesion by Integrins

(2019) Michael Bachmann et al.   PHYSIOLOGICAL REVIEWS

Early skeletal muscle pathology and disease progress in the dy3K/dy3K mouse model of congenital muscular dystrophy with laminin α2 chain-deficiency

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Extracellular matrix/mitochondria pathway: A novel potential target for sarcopenia

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Cell adhesion to collagen promotes leukemia resistance to doxorubicin by reducing DNA damage through the inhibition of Rac1 activation

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Integrin-β4 is a novel transcriptional target of TAp73

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Integrin α6β4-Src-AKT signaling induces cellular senescence by counteracting apoptosis in irradiated tumor cells and tissues

(2018) Seung Hee Jung et al.   CELL DEATH AND DIFFERENTIATION

Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome

(2018) Paul Hiebert et al.   DEVELOPMENTAL CELL

Extracellular matrix as a driver of progressive fibrosis

(2018) Jeremy Herrera et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular matrix remodeling and cardiac fibrosis

(2018) Li Li et al.   MATRIX BIOLOGY

β1-Integrin Impacts Rad51 Stability and DNA Double-Strand Break Repair by Homologous Recombination

(2018) Kazi Mokim Ahmed et al.   MOLECULAR AND CELLULAR BIOLOGY

Raf kinase inhibitor protein mediates myocardial fibrosis under conditions of enhanced myocardial oxidative stress

(2018) Andrey Kazakov et al.   BASIC RESEARCH IN CARDIOLOGY

A review of the molecular mechanisms of hyperglycemia-induced free radical generation leading to oxidative stress

(2018) Habib Yaribeygi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Alpha-6 integrin promotes radioresistance of glioblastoma by modulating DNA damage response and the transcription factor Zeb1

(2018) Aline Kowalski-Chauvel et al.   Cell Death & Disease

Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function

(2018) Tina Nybo et al.   Redox Biology

Base excision repair of oxidative DNA damage from mechanism to disease

(2017) Bret D Freudenthal   Frontiers in Bioscience-Landmark

Oxidative stress in Duchenne muscular dystrophy: focus on the NRF2 redox pathway

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Laminin-deficient muscular dystrophy: Molecular pathogenesis and structural repair strategies

(2017) Peter D. Yurchenco et al.   MATRIX BIOLOGY

Wild-type p53 controls the level of fibronectin expression in breast cancer cells

(2017) Daeun You et al.   ONCOLOGY REPORTS

Osteogenesis imperfecta

(2017) Joan C. Marini et al.   Nature Reviews Disease Primers

Bioenergetic Impairment in Congenital Muscular Dystrophy Type 1A and Leigh Syndrome Muscle Cells

(2017) Cibely C. Fontes-Oliveira et al.   Scientific Reports

Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3

(2016) Nishant P. Visavadiya et al.   Cell Communication and Signaling

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Syndecans - key regulators of cell signaling and biological functions

(2016) Nikolaos A. Afratis et al.   FEBS Journal

The extracellular matrix: Tools and insights for the “omics” era

(2016) Alexandra Naba et al.   MATRIX BIOLOGY

Collagen metabolic disorder induced by oxidative stress in human uterosacral ligament-derived fibroblasts: A possible pathophysiological mechanism in pelvic organ prolapse

(2016) CHENG LIU et al.   Molecular Medicine Reports

p53 in the DNA-Damage-Repair Process

(2016) Ashley B. Williams et al.   Cold Spring Harbor Perspectives in Medicine

Mitochondrial ROS Signaling in Organismal Homeostasis

(2015) Gerald S. Shadel et al.   CELL

The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship

(2015) Boris Hinz   MATRIX BIOLOGY

Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression

(2015) Jelena Krstić et al.   Oxidative Medicine and Cellular Longevity

Tumor Necrosis Factor - Alpha Is Essential for Angiotensin II-Induced Ventricular Remodeling: Role for Oxidative Stress

(2015) Srinivas Sriramula et al.   PLoS One

Monoamine oxidase inhibition prevents mitochondrial dysfunction and apoptosis in myoblasts from patients with collagen VI myopathies

(2014) E. Sorato et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress in muscular dystrophy: from generic evidence to specific sources and targets

(2014) Marcella Canton et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Quantitative Proteomic Analysis Reveals Metabolic Alterations, Calcium Dysregulation, and Increased Expression of Extracellular Matrix Proteins in Laminin α2 Chain–deficient Muscle

(2014) Bruno Menezes de Oliveira et al.   MOLECULAR & CELLULAR PROTEOMICS

Stress, Inflammation, and Defense of Homeostasis

(2014) Raj Chovatiya et al.   MOLECULAR CELL

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA Damage Response Genes and the Development of Cancer Metastasis

(2014) Constantinos G. Broustas et al.   RADIATION RESEARCH

p53 Family and Cellular Stress Responses in Cancer

(2014) Johanna Pflaum et al.   Frontiers in Oncology

Redox-Relevant Aspects of the Extracellular Matrix and Its Cellular Contacts via Integrins

(2013) Johannes A. Eble et al.   ANTIOXIDANTS & REDOX SIGNALING

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(2013) Michelle K. Zeman et al.   NATURE CELL BIOLOGY

Mitochondrial Dysfunction and Defective Autophagy in the Pathogenesis of Collagen VI Muscular Dystrophies

(2013) P. Bernardi et al.   Cold Spring Harbor Perspectives in Biology

Laminin isoforms in endothelial and perivascular basement membranes

(2013) Lema F. Yousif et al.   Cell Adhesion & Migration

Oxidative stress and pulmonary fibrosis

(2012) Paul Cheresh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Role of Oxidative Stress and Molecular Changes in Liver Fibrosis: A Review

(2012) V. Sanchez-Valle et al.   CURRENT MEDICINAL CHEMISTRY

Diabetes-Induced Alterations in the Extracellular Matrix and Their Impact on Myocardial Function

(2012) Brittany Law et al.   MICROSCOPY AND MICROANALYSIS

The inside and out of dystroglycan post-translational modification

(2012) Chris J. Moore et al.   NEUROMUSCULAR DISORDERS

ATM-Mediated DNA Damage Signals Mediate Immune Escape through Integrin- v 3-Dependent Mechanisms

(2011) M. Jinushi et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The collagen VI-related myopathies: muscle meets its matrix

(2011) Carsten G. Bönnemann   Nature Reviews Neurology

Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions

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Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies

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Crosstalk of reactive oxygen species and NF-κB signaling

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Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress by monoamine oxidases is causally involved in myofiber damage in muscular dystrophy

(2010) Sara Menazza et al.   HUMAN MOLECULAR GENETICS

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

(2010) Nicholas P. Whitehead et al.   PLoS One

The role of PGC-1α on mitochondrial function and apoptotic susceptibility in muscle

(2009) Peter J. Adhihetty et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Angiotensin II, mitochondria, cytoskeletal, and extracellular matrix connections: an integrating viewpoint

(2009) Elena MV de Cavanagh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix

(2009) A. D. Kandasamy et al.   CARDIOVASCULAR RESEARCH

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

(2009) Elena Palma et al.   HUMAN MOLECULAR GENETICS

The extracellular matrix: At the center of it all

(2009) Stephanie L.K. Bowers et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

(2009) Zachary T. Schafer et al.   NATURE

Reciprocal amplification of ROS and Ca2+ signals in stressed mdx dystrophic skeletal muscle fibers

(2009) Vyacheslav M. Shkryl et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Oxidative stress in bone remodelling and disease

(2009) Fabien Wauquier et al.   TRENDS IN MOLECULAR MEDICINE

Collagen Fragmentation Promotes Oxidative Stress and Elevates Matrix Metalloproteinase-1 in Fibroblasts in Aged Human Skin

(2008) Gary J. Fisher et al.   AMERICAN JOURNAL OF PATHOLOGY

N-Acetylcysteine ameliorates skeletal muscle pathophysiology inmdxmice

(2008) Nicholas P. Whitehead et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxidative stress mediates cardiac fibrosis by enhancing transforming growth factor-beta1 in hypertensive rats

(2008) Wenyuan Zhao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

(2008) Douglas P Millay et al.   NATURE MEDICINE

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies

(2008) Luciano Merlini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA