Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering

Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

(2021) Philipp Rhein et al.   Molecular Metabolism

Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

(2020) Janne R. Hingst et al.   Molecular Metabolism

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress

(2019) Yue Zong et al.   CELL RESEARCH

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

(2017) Robert W. Myers et al.   SCIENCE

Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

(2016) Laurent Bultot et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Intact Regulation of the AMPK Signaling Network in Response to Exercise and Insulin in Skeletal Muscle of Male Patients With Type 2 Diabetes: Illumination of AMPK Activation in Recovery From Exercise

(2016) Rasmus Kjøbsted et al.   DIABETES

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

(2016) Rasmus Kjøbsted et al.   DIABETES

AMP-activated protein kinase: a cellular energy sensor that comes in 12 flavours

(2016) Fiona A. Ross et al.   FEBS Journal

Probing the enzyme kinetics, allosteric modulation and activation of  1- and  2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators

(2015) F. Rajamohan et al.   BIOCHEMICAL JOURNAL

Differential regulation by AMP and ADP of AMPK complexes containing different   subunit isoforms

(2015) F. A. Ross et al.   BIOCHEMICAL JOURNAL

The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle

(2015) Jacqueline Stöckli et al.   DIABETES

Human muscle fibre type-specific regulation of AMPK and downstream targets by exercise

(2015) Dorte E. Kristensen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Prior AICAR Stimulation Increases Insulin Sensitivity in Mouse Skeletal Muscle in an AMPK-Dependent Manner

(2015) Rasmus Kjøbsted et al.   DIABETES

Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662

(2014) Serge Ducommun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators

(2014) Yu-Chiang Lai et al.   BIOCHEMICAL JOURNAL

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity

(2014) Louise Lantier et al.   FASEB JOURNAL

Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms

(2014) Matthew F. Calabrese et al.   STRUCTURE

Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity

(2010) Gregory R. Steinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A-769662 activates AMPK β1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

(2009) Jonas T. Treebak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY