Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

Type 2 Diabetes Medication Review

(2016) James J. Sterrett et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Future glucose-lowering drugs for type 2 diabetes

(2016) Clifford J Bailey et al.   Lancet Diabetes & Endocrinology

AMP-Activated Protein Kinase: Maintaining Energy Homeostasis at the Cellular and Whole-Body Levels

(2014) D. Grahame Hardie   Annual Review of Nutrition

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators

(2014) Yu-Chiang Lai et al.   BIOCHEMICAL JOURNAL

Mutation in the γ2-Subunit of AMP-Activated Protein Kinase Stimulates Cardiomyocyte Proliferation and Hypertrophy Independent of Glycogen Storage

(2014) Maengjo Kim et al.   CIRCULATION RESEARCH

Beyond HbA1c and Glucose: the Role of Nontraditional Glycemic Markers in Diabetes Diagnosis, Prognosis, and Management

(2014) Christina M. Parrinello et al.   Current Diabetes Reports

AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease

(2014) D. Grahame Hardie   JOURNAL OF INTERNAL MEDICINE

Small Molecule Adenosine 5′-Monophosphate Activated Protein Kinase (AMPK) Modulators and Human Diseases

(2014) Sandeep Rana et al.   JOURNAL OF MEDICINAL CHEMISTRY

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

(2013) Morgan D Fullerton et al.   NATURE MEDICINE

Exercise, GLUT4, and Skeletal Muscle Glucose Uptake

(2013) Erik A. Richter et al.   PHYSIOLOGICAL REVIEWS

Structural basis of AMPK regulation by small molecule activators

(2013) Bing Xiao et al.   Nature Communications

AMPK and Exercise: Glucose Uptake and Insulin Sensitivity

(2013) Hayley M. O'Neill   Diabetes & Metabolism Journal

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Murine models for pharmacological studies of the metabolic syndrome

(2012) Lyne Fellmann et al.   PHARMACOLOGY & THERAPEUTICS

Molecular Mechanism by Which AMP-Activated Protein Kinase Activation Promotes Glycogen Accumulation in Muscle

(2011) Roger W. Hunter et al.   DIABETES

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies

(2010) Bianca C. Bernardo et al.   PHARMACOLOGY & THERAPEUTICS

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Reversibility of PRKAG2 Glycogen-Storage Cardiomyopathy and Electrophysiological Manifestations

(2007) Cordula M. Wolf et al.   CIRCULATION