Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis
出版年份 2021 全文链接
标题
Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis
作者
关键词
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出版物
Frontiers in Pharmacology
Volume 12, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-08-16
DOI
10.3389/fphar.2021.719880
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Glucocorticoid therapy suppresses Wnt signaling by reducing the ratio of serum Wnt3a to Wnt inhibitors, sFRP-1 and Wif-1
- (2021) Mai Kawazoe et al. CLINICAL RHEUMATOLOGY
- Protective role of kallistatin in renal fibrosis via modulation of Wnt/β-catenin signaling
- (2021) Wai Han Yiu et al. CLINICAL SCIENCE
- FoxM1 promotes Wnt/β‐catenin pathway activation and renal fibrosis via transcriptionally regulating multi‐Wnts expressions
- (2021) Hongyan Xie et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Relationship between serum Dickkopf-1 and albuminuria in patients with type 2 diabetes
- (2021) Ning-Ning Hou et al. World Journal of Diabetes
- Epigenetic modifications of Klotho expression in kidney diseases
- (2021) Jinkun Xia et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- A Rationale for Drug Design Provided by Co-Crystal Structure of IC261 in Complex with Tubulin
- (2021) Jinghong Xian et al. MOLECULES
- Polyporus Umbellatus Protects Against Renal Fibrosis by Regulating Intrarenal Fatty Acyl Metabolites
- (2021) Yan-Ni Wang et al. Frontiers in Pharmacology
- Qishen Yiqi Dripping Pill Protects Against Diabetic Nephropathy by Inhibiting the Wnt/β-Catenin and Transforming Growth Factor-β/Smad Signaling Pathways in Rats
- (2021) Qian Zhang et al. Frontiers in Physiology
- The Dysregulation of Eicosanoids and Bile Acids Correlates with Impaired Kidney Function and Renal Fibrosis in Chronic Renal Failure
- (2021) Yan-Ni Wang et al. Metabolites
- AGE/RAGE in diabetic kidney disease and ageing kidney
- (2021) Xia-Qing Wu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Key metalloproteinase-mediated pathways in the kidney
- (2021) Justyna Wozniak et al. Nature Reviews Nephrology
- Effects of TRPC6 Inactivation on Glomerulosclerosis and Renal Fibrosis in Aging Rats
- (2021) Eun Young Kim et al. Cells
- Apigenin ameliorates hyperuricemic nephropathy by inhibiting URAT1 and GLUT9 and relieving renal fibrosis via the Wnt/β-catenin pathway
- (2021) Yongmei Li et al. PHYTOMEDICINE
- Stem cells in the treatment of renal fibrosis: a review of preclinical and clinical studies of renal fibrosis pathogenesis
- (2021) Yiping Liu et al. Stem Cell Research & Therapy
- Selective Wnt/β-Catenin Pathway Activation Concomitant With Sustained Overexpression of miR-21 is Responsible for Aristolochic Acid-Induced AKI-to-CKD Transition
- (2021) Qing Kuang et al. Frontiers in Pharmacology
- The (pro)renin receptor: a novel biomarker and potential therapeutic target for various cancers
- (2020) Juan Wang et al. Cell Communication and Signaling
- Deletion of FHL2 in fibroblasts attenuates fibroblasts activation and kidney fibrosis via restraining TGF-β1-induced Wnt/β-catenin signaling
- (2020) Ying Duan et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement
- (2020) Qian Wang et al. Journal of Diabetes Research
- Identification of endogenous 1‐aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation
- (2020) Hua Miao et al. BRITISH JOURNAL OF PHARMACOLOGY
- Salidroside protects against Diabetes Mellitus‐induced kidney injury and renal fibrosis by attenuating TGF‐β1 and Wnt1/3a/β‐catenin signaling
- (2020) Ali A. Shati et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Wnt/β-Catenin in Acute Kidney Injury and Progression to Chronic Kidney Disease
- (2020) Tessa Huffstater et al. SEMINARS IN NEPHROLOGY
- Klotho/FGF23 and Wnt Signaling as Important Players in the Comorbidities Associated with Chronic Kidney Disease
- (2020) Juan Rafael Muñoz-Castañeda et al. Toxins
- The MicroRNA MiR-29c Alleviates Renal Fibrosis via TPM1-Mediated Suppression of the Wnt/β-Catenin Pathway
- (2020) Huiya Huang et al. Frontiers in Physiology
- The Role of Wnt Signalling in Chronic Kidney Disease (CKD)
- (2020) Soniya A. Malik et al. Genes
- Wnt signaling pathway in aging-related tissue fibrosis and therapies
- (2020) He-He Hu et al. AGEING RESEARCH REVIEWS
- First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor
- (2020) Ruth Plummer et al. BRITISH JOURNAL OF CANCER
- Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis
- (2020) Dan-Qian Chen et al. PHYTOMEDICINE
- Huangkui Capsule Ameliorates Renal Fibrosis in a Unilateral Ureteral Obstruction Mouse Model Through TRPC6 Dependent Signaling Pathways
- (2020) Li-fei Gu et al. Frontiers in Pharmacology
- Progress in drug delivery system for fibrosis therapy
- (2020) Lei Xing et al. Asian Journal of Pharmaceutical Sciences
- The Many Faces of Matrix Metalloproteinase-7 in Kidney Diseases
- (2020) Zhao Liu et al. Biomolecules
- Renal tubular cell binding of β‐catenin to TCF1 versus FoxO1 is associated with chronic interstitial fibrosis in transplanted kidneys
- (2020) Ying Yang et al. AMERICAN JOURNAL OF TRANSPLANTATION
- microRNA27a-3p mediates reduction of the Wnt antagonist sFRP-1 in systemic sclerosis
- (2020) John Henderson et al. Epigenetics
- Alleviation by Mahuang Fuzi and Shenzhuo Decoction in High Glucose-Induced Podocyte Injury by Inhibiting the Activation of Wnt/β-Catenin Signaling Pathway, Resulting in Activation of Podocyte Autophagy
- (2020) Haoran Dai et al. Evidence-based Complementary and Alternative Medicine
- Wnt/β-catenin agonist BIO alleviates cisplatin-induced nephrotoxicity without compromising its efficacy of anti-proliferation in ovarian cancer
- (2020) Zhaoxing Sun et al. LIFE SCIENCES
- WNT–β-catenin signalling — a versatile player in kidney injury and repair
- (2020) Stefan J. Schunk et al. Nature Reviews Nephrology
- LINC00052 ameliorates acute kidney injury by sponging miR-532-3p and activating the Wnt signaling pathway
- (2020) Xiaoying Li et al. Aging-US
- Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site
- (2020) Ido Rippin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Deciphering the cellular mechanisms underlying fibrosis-associated diseases and therapeutic avenues
- (2020) Hua Miao et al. PHARMACOLOGICAL RESEARCH
- Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation
- (2020) Ming Wang et al. PHYTOMEDICINE
- Cannabinoid receptor type 2 promotes kidney fibrosis through orchestrating β-catenin signaling
- (2020) Shan Zhou et al. KIDNEY INTERNATIONAL
- Protective or deleterious role of Wnt/beta-catenin signaling in diabetic nephropathy: An unresolved issue
- (2019) Qiaoyan Guo et al. PHARMACOLOGICAL RESEARCH
- Macrophages: versatile players in renal inflammation and fibrosis
- (2019) Patrick Ming-Kuen Tang et al. Nature Reviews Nephrology
- The Matrix Metalloproteinase‐13 Inhibitor Poricoic Acid ZI Ameliorates Renal Fibrosis by Mitigating Epithelial‐Mesenchymal Transition
- (2019) Lin Chen et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Wnt/β-catenin regulates blood pressure and kidney injury in rats
- (2019) Liangxiang Xiao et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation
- (2019) John-Poul Ng-Blichfeldt et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Activated NF-κB/Nrf2 and Wnt/β-catenin pathways are associated with lipid metabolism in CKD patients with microalbuminuria and macroalbuminuria
- (2019) Ya-Long Feng et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Role of TRPC6 in Progression of Diabetic Kidney Disease
- (2019) Alexander Staruschenko et al. CURRENT HYPERTENSION REPORTS
- Qingshen Buyang Formula Attenuates Renal Fibrosis in 5/6 Nephrectomized Rats via Inhibiting EMT and Wnt/β-Catenin Pathway
- (2019) Xueqin Zhang et al. Evidence-based Complementary and Alternative Medicine
- Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/Axl NF κB/Nrf2 axis
- (2019) Dan-Qian Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Small molecule inhibitors of epithelial‐mesenchymal transition for the treatment of cancer and fibrosis
- (2019) Ya‐Long Feng et al. MEDICINAL RESEARCH REVIEWS
- Fibroblast-specific plasminogen activator inhibitor-1 depletion ameliorates renal interstitial fibrosis after unilateral ureteral obstruction
- (2019) Lan Yao et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Targeting the crosstalks of Wnt pathway with Hedgehog and Notch for cancer therapy
- (2019) Sharmistha Chatterjee et al. PHARMACOLOGICAL RESEARCH
- Wnt/β‐catenin/RAS signaling mediates age‐related renal fibrosis and is associated with mitochondrial dysfunction
- (2019) Jinhua Miao et al. AGING CELL
- Microbiome–metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease
- (2019) Ya-Long Feng et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The (pro)renin receptor in health and disease
- (2019) Atsuhiro Ichihara et al. Nature Reviews Nephrology
- Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan
- (2019) Dan-Qian Chen et al. Nature Communications
- Small molecules from natural products targeting the Wnt/β-catenin pathway as a therapeutic strategy
- (2019) Dan Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- WNT1‐inducible signaling protein‐1 mediates TGF‐β1‐induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy
- (2019) Xue Yang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The regulation effect of WNT-RAS signaling in hypothalamic paraventricular nucleus on renal fibrosis
- (2019) Guang Zhou et al. JOURNAL OF NEPHROLOGY
- The deacetylase sirtuin 6 protects against kidney fibrosis by epigenetically blocking β-catenin target gene expression
- (2019) Juan Cai et al. KIDNEY INTERNATIONAL
- Effect of sitagliptin on tubulointerstitial Wnt/β‐catenin signalling in diabetic nephropathy
- (2019) Xiaojun Ren et al. NEPHROLOGY
- Qishen granule attenuates cardiac fibrosis by regulating TGF-β /Smad3 and GSK-3β pathway
- (2019) Zifan Zeng et al. PHYTOMEDICINE
- Macrophages as an Emerging Source of Wnt Ligands: Relevance in Mucosal Integrity
- (2019) Jesús Cosin-Roger et al. Frontiers in Immunology
- Shared and distinct mechanisms of fibrosis
- (2019) Jörg H. W. Distler et al. Nature Reviews Rheumatology
- TRPC Channels in Proteinuric Kidney Diseases
- (2019) Gentzon Hall et al. Cells
- Targeting renal fibrosis: Mechanisms and drug delivery systems
- (2018) Madalina V. Nastase et al. ADVANCED DRUG DELIVERY REVIEWS
- Mechanisms of Renal Fibrosis
- (2018) Benjamin D. Humphreys Annual Review of Physiology
- Inhibition of canonical WNT signaling pathway by β-catenin/CBP inhibitor ICG-001 ameliorates liver fibrosis in vivo through suppression of stromal CXCL12
- (2018) Büsra Öztürk Akcora et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment
- (2018) Lin Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis
- (2018) Ming Wang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Inhibition of GSK-3β induces AP-1–mediated osteopontin expression to promote cholestatic liver fibrosis
- (2018) Shaoyong Zhuang et al. FASEB JOURNAL
- Novel RAS Inhibitors Poricoic Acid ZG and Poricoic Acid ZH Attenuate Renal Fibrosis via a Wnt/β-Catenin Pathway and Targeted Phosphorylation of smad3 Signaling
- (2018) Ming Wang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- SB-216763, a GSK-3β inhibitor, protects against aldosterone-induced cardiac, and renal injury by activating autophagy
- (2018) Yi-De Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Discovery of a small-molecule inhibitor of Dvl–CXXC5 interaction by computational approaches
- (2018) Songling Ma et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Zhen-wu-tang ameliorates adenine-induced chronic renal failure in rats: regulation of the canonical Wnt4/beta-catenin signaling in the kidneys
- (2018) Lei La et al. JOURNAL OF ETHNOPHARMACOLOGY
- Activated renal tubular Wnt/β-catenin signaling triggers renal inflammation during overload proteinuria
- (2018) Dickson W.L. Wong et al. KIDNEY INTERNATIONAL
- Cellular and molecular mechanisms of kidney fibrosis
- (2018) Sonja Djudjaj et al. MOLECULAR ASPECTS OF MEDICINE
- Dickkopf-3 in aberrant endothelial secretome triggers renal fibroblast activation and endothelial–mesenchymal transition
- (2018) Mark Lipphardt et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Novel RAS inhibitor 25-O-methylalisol F attenuates epithelial-to-mesenchymal transition and tubulo-interstitial fibrosis by selectively inhibiting TGF-β-mediated Smad3 phosphorylation
- (2018) Hua Chen et al. PHYTOMEDICINE
- Tripterygium�wilfordii mitigates hyperglycemia-induced upregulated Wnt/β-catenin expression and kidney injury in diabetic rats
- (2018) Baochao Chang et al. Experimental and Therapeutic Medicine
- An essential role for Wnt/β-catenin signaling in mediating hypertensive heart disease
- (2018) Yue Zhao et al. Scientific Reports
- Macrophages, Wound Healing, and Fibrosis: Recent Insights
- (2018) Kate S. Smigiel et al. Current Rheumatology Reports
- An Integrated Lipidomics and Phenotype Study Reveals Protective Effect and Biochemical Mechanism of Traditionally Used Alisma orientale Juzepzuk in Chronic Kidney Disease
- (2018) Fang Dou et al. Frontiers in Pharmacology
- Dickkopf-1: Current knowledge and related diseases
- (2018) Yu Huang et al. LIFE SCIENCES
- Natural Products as a Source for Antifibrosis Therapy
- (2018) Dan-Qian Chen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury
- (2018) Feng Zhang et al. CELL BIOLOGY INTERNATIONAL
- Wnt/β-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs
- (2018) Koji Nishikawa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Fate alteration of bone marrow-derived macrophages ameliorates kidney fibrosis in murine model of unilateral ureteral obstruction
- (2018) Ying Yang et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Salvia miltiorrhiza protects against diabetic nephropathy through metabolome regulation and wnt/β-catenin and TGF-β signaling inhibition
- (2018) Xiang Xiang et al. PHARMACOLOGICAL RESEARCH
- Activating Wnt/β-catenin signaling pathway for disease therapy: Challenges and opportunities
- (2018) Piao Huang et al. PHARMACOLOGY & THERAPEUTICS
- Differential regulation of renal Klotho and FGFR1 in normal and uremic rats
- (2017) Juan R. Muñoz-Castañeda et al. FASEB JOURNAL
- WNT inhibitory factor 1 promoter hypermethylation is an early event during gallbladder cancer tumorigenesis that predicts poor survival
- (2017) Bin Lin et al. GENE
- Plasminogen Activator Inhibitor Type-1 as a Regulator of Fibrosis
- (2017) Reyhaneh Rabieian et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Blocking TGF-βandβ-Catenin Epithelial Crosstalk Exacerbates CKD
- (2017) Stellor Nlandu-Khodo et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- (Pro)renin Receptor Is an Amplifier of Wnt/ β -Catenin Signaling in Kidney Injury and Fibrosis
- (2017) Zhen Li et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis
- (2017) Dong Zhou et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor–Related Protein 6
- (2017) Bryce G. Johnson et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Wnt/ β -Catenin–Promoted Macrophage Alternative Activation Contributes to Kidney Fibrosis
- (2017) Ye Feng et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Chronic Kidney Disease
- (2017) Angela C Webster et al. LANCET
- Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
- (2017) Claudia Y. Janda et al. NATURE
- WNT Signaling in Cardiac and Vascular Disease
- (2017) Sébastien Foulquier et al. PHARMACOLOGICAL REVIEWS
- Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist
- (2017) Jesung Moon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glycogen synthase kinase-3 inhibition sensitizes human induced pluripotent stem cells to thiol-containing antioxidants induced apoptosis
- (2017) Chengyi Tu et al. Stem Cell Research
- Eucalyptol ameliorates Snail1/β-catenin-dependent diabetic disjunction of renal tubular epithelial cells and tubulointerstitial fibrosis
- (2017) Dong Yeon Kim et al. Oncotarget
- MicroRNA-27a-3p Modulates the Wnt/β-Catenin Signaling Pathway to Promote Epithelial-Mesenchymal Transition in Oral Squamous Carcinoma Stem Cells by Targeting SFRP1
- (2017) Bin Qiao et al. Scientific Reports
- Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease
- (2017) Dan-Qian Chen et al. Redox Biology
- Curcumin Rescues Diabetic Renal Fibrosis by Targeting Superoxide-Mediated Wnt Signaling Pathways
- (2016) Cheng Ho et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Wnt/β-catenin signaling and renin–angiotensin system in chronic kidney disease
- (2016) Lili Zhou et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Traditional uses, fermentation, phytochemistry and pharmacology of Phellinus linteus : A review
- (2016) Hua Chen et al. FITOTERAPIA
- Lipidomics Biomarkers of Diet-Induced Hyperlipidemia and Its Treatment with Poria cocos
- (2016) Hua Miao et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay
- (2016) Melissa V. Gammons et al. JOURNAL OF CELL SCIENCE
- Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog
- (2016) Maria Edeling et al. Nature Reviews Nephrology
- Snail and kidney fibrosis
- (2016) Noémie Simon-Tillaux et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- A unique type of GSK-3 inhibitor brings new opportunities to the clinic
- (2016) A. Licht-Murava et al. Science Signaling
- The Role of Plasminogen Activator Inhibitor Type-1 in Fibrosis
- (2016) Panagiotis Flevaris et al. SEMINARS IN THROMBOSIS AND HEMOSTASIS
- β-Catenin-Independent Roles of Wnt/LRP6 Signaling
- (2016) Sergio P. Acebron et al. TRENDS IN CELL BIOLOGY
- Making, Exporting, and Modulating Wnts
- (2016) Paul F. Langton et al. TRENDS IN CELL BIOLOGY
- Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and β-catenin Signaling
- (2016) Jiafa Ren et al. Scientific Reports
- A unique type of GSK-3 inhibitor brings new opportunities to the clinic
- (2016) A. Licht-Murava et al. Science Signaling
- MicroRNA-130b improves renal tubulointerstitial fibrosis via repression of Snail-induced epithelial-mesenchymal transition in diabetic nephropathy
- (2016) Xiaoyan Bai et al. Scientific Reports
- Triptonide Effectively Inhibits Wnt/β-Catenin Signaling via C-terminal Transactivation Domain of β-catenin
- (2016) Jessica Chinison et al. Scientific Reports
- Klotho Ameliorates Kidney Injury and Fibrosis and Normalizes Blood Pressure by Targeting the Renin-Angiotensin System
- (2015) Lili Zhou et al. AMERICAN JOURNAL OF PATHOLOGY
- Sustained Activation of Wnt/ -Catenin Signaling Drives AKI to CKD Progression
- (2015) L. Xiao et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk
- (2015) O. H. Maarouf et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Wnt/β-catenin signaling in kidney injury and repair: a double-edged sword
- (2015) Dong Zhou et al. LABORATORY INVESTIGATION
- Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells
- (2015) Ozlem Kulak et al. MOLECULAR AND CELLULAR BIOLOGY
- Wnt/β-catenin signalling and podocyte dysfunction in proteinuric kidney disease
- (2015) Lili Zhou et al. Nature Reviews Nephrology
- PAI-1 modulates cell migration in a LRP1-dependent manner via β-catenin and ERK1/2
- (2015) Nina Kozlova et al. THROMBOSIS AND HAEMOSTASIS
- Protective effect of Huang Gan formula in 5/6 nephrectomized rats by depressing the Wnt/β-catenin signaling pathway
- (2015) Liqian Mo et al. Drug Design Development and Therapy
- Podocyte Regeneration Driven by Renal Progenitors Determines Glomerular Disease Remission and Can Be Pharmacologically Enhanced
- (2015) Laura Lasagni et al. Stem Cell Reports
- Astragaloside IV Inhibits the Up-Regulation of Wnt/β-Catenin Signaling in Rats with Unilateral Ureteral Obstruction
- (2014) Li Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Secreted Frizzled-related Protein 1 (Sfrp1) Regulates the Progression of Renal Fibrosis in a Mouse Model of Obstructive Nephropathy
- (2014) Makoto Matsuyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diuretic and anti-diuretic activities of the ethanol and aqueous extracts of Alismatis rhizoma
- (2014) Ya-Long Feng et al. JOURNAL OF ETHNOPHARMACOLOGY
- Diuretic and anti-diuretic activities of fractions of Alismatis rhizoma
- (2014) Dan-Qian Chen et al. JOURNAL OF ETHNOPHARMACOLOGY
- Traditional uses, phytochemistry, pharmacology, toxicology and quality control of Alisma orientale (Sam.) Juzep: A review
- (2014) Ting Tian et al. JOURNAL OF ETHNOPHARMACOLOGY
- Klotho suppresses renal tubulo-interstitial fibrosis by controlling basic fibroblast growth factor-2 signalling
- (2014) Xu Guan et al. JOURNAL OF PATHOLOGY
- The Kidney Is the Principal Organ Mediating Klotho Effects
- (2014) K. Lindberg et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Multiple Genes of the Renin-Angiotensin System Are Novel Targets of Wnt/ -Catenin Signaling
- (2014) L. Zhou et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- CTSB promotes porcine preadipocytes differentiation by degrading fibronectin and attenuating the Wnt/β-catenin signaling pathway
- (2014) Zhen-Yu Zhang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- A Pharmaco-Metabonomic Study on Chronic Kidney Disease and Therapeutic Effect of Ergone by UPLC-QTOF/HDMS
- (2014) Ying-Yong Zhao et al. PLoS One
- Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the Wnt inhibitor WIF-1 in systemic sclerosis and fibrosis
- (2014) S. Svegliati et al. Science Signaling
- Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance
- (2014) Nan Wang et al. Frontiers in Immunology
- Intrarenal renin–angiotensin system in regulation of glomerular function
- (2013) L. Gabriel Navar CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Diuretic activity of some fractions of the epidermis of Poria cocos
- (2013) Ya-Long Feng et al. JOURNAL OF ETHNOPHARMACOLOGY
- General toxicity of Pinellia ternata (Thunb.) Berit. in rat: A metabonomic method for profiling of serum metabolic changes
- (2013) Zhi-Hao Zhang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Urinary metabonomic study of the surface layer of Poria cocos as an effective treatment for chronic renal injury in rats
- (2013) Ying-Yong Zhao et al. JOURNAL OF ETHNOPHARMACOLOGY
- Mycology, cultivation, traditional uses, phytochemistry and pharmacology of Wolfiporia cocos (Schwein.) Ryvarden et Gilb.: A review
- (2013) Yuan-Zhong Wang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Traditional uses, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus (Pers.) Fries: A review
- (2013) Ying-Yong Zhao JOURNAL OF ETHNOPHARMACOLOGY
- The Development of Highly Potent Inhibitors for Porcupine
- (2013) Xiaolei Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Loss of Klotho Contributes to Kidney Injury by Derepression of Wnt/ -Catenin Signaling
- (2013) L. Zhou et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Cooperation, amplification, and feed-back in epithelial–mesenchymal transition
- (2012) Antonio García de Herreros et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer
- (2012) K. D. Proffitt et al. CANCER RESEARCH
- Effect of ergosta-4,6,8(14),22-tetraen-3-one (ergone) on adenine-induced chronic renal failure rat: A serum metabonomic study based on ultra performance liquid chromatography/high-sensitivity mass spectrometry coupled with MassLynx i-FIT algorithm
- (2012) Ying-Yong Zhao et al. CLINICA CHIMICA ACTA
- Involvement of the Intrarenal Renin-Angiotensin System in Experimental Models of Glomerulonephritis
- (2012) Maki Urushihara et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Diuretic activity of the ethanol and aqueous extracts of the surface layer of Poria cocos in rat
- (2012) Ying-Yong Zhao et al. JOURNAL OF ETHNOPHARMACOLOGY
- LRP5 and LRP6 in development and disease
- (2012) Danese M. Joiner et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Secreted and Transmembrane Wnt Inhibitors and Activators
- (2012) C.-M. Cruciat et al. Cold Spring Harbor Perspectives in Biology
- Ergosta-4,6,8(14),22-tetraen-3-one isolated fromPolyporus umbellatusprevents early renal injury in aristolochic acid-induced nephropathy rats
- (2011) Ying-Yong Zhao et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
- (2010) W. R. Henderson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bioactivity-directed isolation, identification of diuretic compounds from Polyporus umbellatus
- (2009) Ying-yong Zhao et al. JOURNAL OF ETHNOPHARMACOLOGY
- Wnt/ -Catenin Signaling Promotes Renal Interstitial Fibrosis
- (2009) W. He et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Snail promotes Wnt target gene expression and interacts with β-catenin
- (2008) V Stemmer et al. ONCOGENE
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