标题
A unique type of GSK-3 inhibitor brings new opportunities to the clinic
作者
关键词
-
出版物
Science Signaling
Volume 9, Issue 454, Pages ra110-ra110
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2016-11-16
DOI
10.1126/scisignal.aah7102
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects
- (2016) Florence F. Wagner et al. ACS Chemical Biology
- Therapeutic strategies for the treatment of tauopathies: Hopes and challenges
- (2016) Mansi R. Khanna et al. Alzheimers & Dementia
- Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging
- (2016) Steven H. Liang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The contribution of astrocytes to Alzheimer's disease
- (2014) Amy M. Birch BIOCHEMICAL SOCIETY TRANSACTIONS
- Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth
- (2014) I Azoulay-Alfaguter et al. ONCOGENE
- Repetitive and Stereotypic Phenomena and Dementia
- (2013) Gabriele Cipriani et al. American Journal of Alzheimers Disease and Other Dementias
- An Overview of Autophagy: Morphology, Mechanism, and Regulation
- (2013) Katherine R. Parzych et al. ANTIOXIDANTS & REDOX SIGNALING
- Glycogen Synthase Kinase-3 Inhibitors Reverse Deficits in Long-term Potentiation and Cognition in Fragile X Mice
- (2013) Aimee V. Franklin et al. BIOLOGICAL PSYCHIATRY
- Regulation of Th1 Cells and Experimental Autoimmune Encephalomyelitis by Glycogen Synthase Kinase-3
- (2013) E. Beurel et al. JOURNAL OF IMMUNOLOGY
- Tau pathology and neurodegeneration
- (2013) Maria Grazia Spillantini et al. LANCET NEUROLOGY
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- Object recognition test in mice
- (2013) Marianne Leger et al. Nature Protocols
- Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments
- (2013) Margaret K. King et al. PHARMACOLOGY & THERAPEUTICS
- Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model
- (2012) Limor Avrahami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes
- (2012) Philip T.T. Ly et al. JOURNAL OF CLINICAL INVESTIGATION
- Selectively Silencing GSK-3 Isoforms Reduces Plaques and Tangles in Mouse Models of Alzheimer's Disease
- (2012) D. E. Hurtado et al. JOURNAL OF NEUROSCIENCE
- Autophagy modulation as a potential therapeutic target for diverse diseases
- (2012) David C. Rubinsztein et al. NATURE REVIEWS DRUG DISCOVERY
- Elucidating Substrate and Inhibitor Binding Sites on the Surface of GSK-3β and the Refinement of a Competitive Inhibitor
- (2011) Avital Licht-Murava et al. JOURNAL OF MOLECULAR BIOLOGY
- GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS
- (2011) Hagit Eldar-Finkelman et al. Frontiers in Molecular Neuroscience
- Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
- (2010) Ju-Hyun Lee et al. CELL
- Role of glycogen synthase kinase-3 in Alzheimer’s disease pathogenesis and glycogen synthase kinase-3 inhibitors
- (2010) Jesús Avila et al. Expert Review of Neurotherapeutics
- The neurobiology of repetitive behavior: Of mice…
- (2010) Marieke Langen et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process
- (2010) Bart De Strooper PHYSIOLOGICAL REVIEWS
- GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism
- (2010) Marjelo A. Mines et al. PLoS One
- Suppression of glycogen synthase kinase 3 activity reduces tumor growth of prostate cancer in vivo
- (2010) Qing Zhu et al. PROSTATE
- Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of Fragile X syndrome
- (2009) Christopher J. Yuskaitis et al. BIOCHEMICAL PHARMACOLOGY
- The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal
- (2009) John Hardy JOURNAL OF NEUROCHEMISTRY
- A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo
- (2009) L. Serenó et al. NEUROBIOLOGY OF DISEASE
- Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
- (2009) Diane P. Hanger et al. TRENDS IN MOLECULAR MEDICINE
- Abnormalities in brain structure and behavior in GSK-3alpha mutant mice
- (2009) Oksana Kaidanovich-Beilin et al. Molecular Brain
- A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics
- (2008) Hanna Rosenmann et al. EXPERIMENTAL NEUROLOGY
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