Investigating Post-translational Modifications in Neuropsychiatric Disease: The Next Frontier in Human Post-mortem Brain Research

MAP2 is differentially phosphorylated in schizophrenia, altering its function

(2021) M. J. Grubisha et al.   MOLECULAR PSYCHIATRY

Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function

(2021) Amanda M. Vanderplow et al.   NEURON

Rapid and deep-scale ubiquitylation profiling for biology and translational research

(2020) Namrata D. Udeshi et al.   Nature Communications

Human organoids to model the developing human neocortex in health and disease

(2020) Shokoufeh Khakipoor et al.   BRAIN RESEARCH

Understanding Cortical Dysfunction in Schizophrenia With TMS/EEG

(2020) Aadith Vittala et al.   Frontiers in Neuroscience

Transcriptomic Insight Into the Polygenic Mechanisms Underlying Psychiatric Disorders

(2020) Leanna M. Hernandez et al.   BIOLOGICAL PSYCHIATRY

Optimal Dissociation Methods Differ for N- and O-Glycopeptides

(2020) Nicholas M. Riley et al.   JOURNAL OF PROTEOME RESEARCH

Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer’s disease

(2020) Lingyan Ping et al.   Scientific Data

Density of small dendritic spines and microtubule-associated-protein-2 immunoreactivity in the primary auditory cortex of subjects with schizophrenia

(2019) Brandon C. McKinney et al.   NEUROPSYCHOPHARMACOLOGY

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

Intracellular compartment-specific proteasome dysfunction in postmortem cortex in schizophrenia subjects

(2019) Madeline R. Scott et al.   MOLECULAR PSYCHIATRY

Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia

(2019) Leslie G. Nucifora et al.   AMERICAN JOURNAL OF PSYCHIATRY

Changes in the global burden of depression from 1990 to 2017: Findings from the Global Burden of Disease study

(2019) Qingqing Liu et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Synaptic Proteome Alterations in the Primary Auditory Cortex of Individuals With Schizophrenia

(2019) Matthew L. MacDonald et al.   JAMA Psychiatry

Organoid and Assembloid Technologies for Investigating Cellular Crosstalk in Human Brain Development and Disease

(2019) Rebecca M. Marton et al.   TRENDS IN CELL BIOLOGY

Global Epidemiology and Burden of Schizophrenia: Findings From the Global Burden of Disease Study 2016

(2018) Fiona J Charlson et al.   SCHIZOPHRENIA BULLETIN

Phosphorylation of different tau sites during progression of Alzheimer’s disease

(2018) Joerg Neddens et al.   Acta Neuropathologica Communications

Single cell protein analysis for systems biology

(2018) Ezra Levy et al.   Essays in Biochemistry

mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia

(2018) Hoau-Yan Wang et al.   MOLECULAR PSYCHIATRY

The benefits of hybrid fragmentation methods for glycoproteomics

(2018) Karli R. Reiding et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Phosphopeptide Fragmentation and Site Localization by Mass Spectrometry: An Update

(2018) Clement M. Potel et al.   ANALYTICAL CHEMISTRY

Laser capture microdissection–targeted mass spectrometry: a method for multiplexed protein quantification within individual layers of the cerebral cortex

(2018) Matthew L. MacDonald et al.   NEUROPSYCHOPHARMACOLOGY

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

(2018) Michael J. Gandal et al.   SCIENCE

Synaptopathology Involved in Autism Spectrum Disorder

(2018) Shiqi Guang et al.   Frontiers in Cellular Neuroscience

Ultrastructural analysis of parvalbumin synapses in human dorsolateral prefrontal cortex

(2017) Jill R. Glausier et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A multiregional proteomic survey of the postnatal human brain

(2017) Becky C. Carlyle et al.   NATURE NEUROSCIENCE

Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging

(2017) Mohan Pabba et al.   NEUROBIOLOGY OF AGING

Proteolysis, synaptic plasticity and memory

(2017) Ashok N. Hegde   NEUROBIOLOGY OF LEARNING AND MEMORY

qSVA framework for RNA quality correction in differential expression analysis

(2017) Andrew E. Jaffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The prevalence and burden of bipolar disorder: findings from the Global Burden of Disease Study 2013

(2016) Alize J Ferrari et al.   BIPOLAR DISORDERS

Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models

(2016) Verónica Martínez-Cerdeño   Developmental Neurobiology

Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer’s disease-related signaling

(2016) D A Bangasser et al.   MOLECULAR PSYCHIATRY

Loss of Microtubule-Associated Protein 2 Immunoreactivity Linked to Dendritic Spine Loss in Schizophrenia

(2015) Micah A. Shelton et al.   BIOLOGICAL PSYCHIATRY

Transcription factor SP4 phosphorylation is altered in the postmortem cerebellum of bipolar disorder and schizophrenia subjects

(2015) Raquel Pinacho et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic Plasticity

(2015) Kevin M. Woolfrey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GABAergic mechanisms of hippocampal hyperactivity in schizophrenia

(2015) Stephan Heckers et al.   SCHIZOPHRENIA RESEARCH

RNA-seq: impact of RNA degradation on transcript quantification

(2014) Irene Gallego Romero et al.   BMC BIOLOGY

Altered serine/threonine kinase activity in schizophrenia

(2014) Jennifer L. McGuire et al.   BRAIN RESEARCH

Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia

(2014) M Föcking et al.   MOLECULAR PSYCHIATRY

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Synapse Assembly and Neurodevelopmental Disorders

(2014) Philip Washbourne   NEUROPSYCHOPHARMACOLOGY

The Diminished Pipeline for Medications to Treat Mental Health and Substance Use Disorders

(2014) Peggy L. O'Brien et al.   PSYCHIATRIC SERVICES

The epidemiology and global burden of autism spectrum disorders

(2014) A. J. Baxter et al.   PSYCHOLOGICAL MEDICINE

Prefrontal Cortical Dendritic Spine Pathology in Schizophrenia and Bipolar Disorder

(2014) Glenn T. Konopaske et al.   JAMA Psychiatry

Altered parvalbumin basket cell inputs in the dorsolateral prefrontal cortex of schizophrenia subjects

(2013) J R Glausier et al.   MOLECULAR PSYCHIATRY

N-Glycosylation of GABAA Receptor Subunits is Altered in Schizophrenia

(2013) Toni Marie Mueller et al.   NEUROPSYCHOPHARMACOLOGY

Dysfunction of the Ubiquitin Proteasome and Ubiquitin-Like Systems in Schizophrenia

(2013) María D Rubio et al.   NEUROPSYCHOPHARMACOLOGY

N-linked glycosylation of cortical N-methyl-D-aspartate and kainate receptor subunits in schizophrenia

(2013) Janusz Tucholski et al.   NEUROREPORT

Intracortical excitatory and thalamocortical boutons are intact in primary auditory cortex in schizophrenia

(2013) Caitlin E. Moyer et al.   SCHIZOPHRENIA RESEARCH

Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophrenia

(2013) Janusz Tucholski et al.   SCHIZOPHRENIA RESEARCH

Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses

(2013) Hyejung Won et al.   Frontiers in Molecular Neuroscience

Synaptopathies: diseases of the synaptome

(2012) Seth GN Grant   CURRENT OPINION IN NEUROBIOLOGY

Biochemical Fractionation and Stable Isotope Dilution Liquid Chromatography-mass Spectrometry for Targeted and Microdomain-specific Protein Quantification in Human Postmortem Brain Tissue

(2012) Matthew L. MacDonald et al.   MOLECULAR & CELLULAR PROTEOMICS

Systematic Analysis of Protein Phosphorylation Networks From Phosphoproteomic Data

(2012) Chunxia Song et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteomics Tackling Schizophrenia as a Pathway Disorder

(2012) D. Martins-de-Souza   SCHIZOPHRENIA BULLETIN

Cortical Glutamic Acid Decarboxylase 67 Deficiency Results in Lower Cannabinoid 1 Receptor Messenger RNA Expression: Implications for Schizophrenia

(2011) Stephen M. Eggan et al.   BIOLOGICAL PSYCHIATRY

A quantitative meta-analysis of fMRI studies in bipolar disorder

(2011) Chi-Hua Chen et al.   BIPOLAR DISORDERS

Isolation of synaptic terminals from Alzheimer's disease cortex

(2011) Sophie Sokolow et al.   CYTOMETRY PART A

Evaluation of HCD- and CID-type Fragmentation Within Their Respective Detection Platforms For Murine Phosphoproteomics

(2011) Mark P. Jedrychowski et al.   MOLECULAR & CELLULAR PROTEOMICS

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Glutamate induces de novo growth of functional spines in developing cortex

(2011) Hyung-Bae Kwon et al.   NATURE

Ubiquitination in Postsynaptic Function and Plasticity

(2010) Angela M. Mabb et al.   Annual Review of Cell and Developmental Biology

Mitochondria in the striatum of subjects with schizophrenia: Relationship to treatment response

(2010) Shahza M. Somerville et al.   SYNAPSE

Meta-analysis of 41 Functional Neuroimaging Studies of Executive Function in Schizophrenia

(2009) Michael J. Minzenberg et al.   ARCHIVES OF GENERAL PSYCHIATRY

KEA: kinase enrichment analysis

(2009) A. Lachmann et al.   BIOINFORMATICS

Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies

(2009) David A. Lewis et al.   JOURNAL OF CLINICAL INVESTIGATION

NMDA Receptor Phosphorylation at a Site Affected in Schizophrenia Controls Synaptic and Behavioral Plasticity

(2009) B. Li et al.   JOURNAL OF NEUROSCIENCE

The Post-Synaptic Density of Human Postmortem Brain Tissues: An Experimental Study Paradigm for Neuropsychiatric Illnesses

(2009) Chang-Gyu Hahn et al.   PLoS One

Reduced Dendritic Spine Density in Auditory Cortex of Subjects with Schizophrenia

(2008) Robert A Sweet et al.   NEUROPSYCHOPHARMACOLOGY