Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer
出版年份 2016 全文链接
标题
Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer
作者
关键词
-
出版物
GENES & DEVELOPMENT
Volume 30, Issue 7, Pages 772-785
出版商
Cold Spring Harbor Laboratory
发表日期
2016-03-18
DOI
10.1101/gad.275529.115
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Quantitative Profiling of the Activity of Protein Lysine Methyltransferase SMYD2 Using SILAC-Based Proteomics
- (2016) Jonathan B. Olsen et al. MOLECULAR & CELLULAR PROTEOMICS
- A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer
- (2015) Felix Dietlein et al. CELL
- Emerging roles of lysine methylation on non-histone proteins
- (2015) Xi Zhang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The Histone Methyltransferase Smyd2 Is a Negative Regulator of Macrophage Activation by Suppressing Interleukin 6 (IL-6) and Tumor Necrosis Factor α (TNF-α) Production
- (2015) Guiliang Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
- (2015) Pawel K Mazur et al. NATURE MEDICINE
- Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma
- (2015) L R Palam et al. Cell Death & Disease
- The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
- (2015) Yongjie Wei et al. eLife
- Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN
- (2015) Makoto Nakakido et al. NEOPLASIA
- Genetic alterations of histone lysine methyltransferases and their significance in breast cancer
- (2015) Lanxin Liu et al. Oncotarget
- RB1 Methylation by SMYD2 Enhances Cell Cycle Progression through an Increase of RB1 Phosphorylation
- (2015) Hyun-Soo Cho et al. NEOPLASIA
- Histone-binding domains: Strategies for discovery and characterization
- (2014) Alex W. Wilkinson et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis
- (2014) Amna Sajjad et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Overexpression of SMYD2 contributes to malignant outcome in gastric cancer
- (2014) S Komatsu et al. BRITISH JOURNAL OF CANCER
- SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation
- (2014) Ryuji Hamamoto et al. CANCER LETTERS
- SMYD2 is highly expressed in pediatric acute lymphoblastic leukemia and constitutes a bad prognostic factor
- (2014) Luis Henrique Toshihiro Sakamoto et al. LEUKEMIA RESEARCH
- SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
- (2014) Pawel K. Mazur et al. NATURE
- The Histone Methyltransferase SMYD2 Methylates PARP1 and Promotes Poly(ADP-ribosyl)ation Activity in Cancer Cells
- (2014) Lianhua Piao et al. NEOPLASIA
- Inflammation, Autophagy, and Obesity: Common Features in the Pathogenesis of Pancreatitis and Pancreatic Cancer
- (2013) Ilya Gukovsky et al. GASTROENTEROLOGY
- The emerging role of the Nrf2-Keap1 signaling pathway in cancer
- (2013) M. C. Jaramillo et al. GENES & DEVELOPMENT
- SMYD2 is induced during cell differentiation and participates in early development
- (2013) Borja Sesé et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation
- (2013) Purvesh Khatri et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase–driven tumors
- (2013) Katherine L Jameson et al. NATURE MEDICINE
- Regulation of estrogen receptor by histone methyltransferase SMYD2-mediated protein methylation
- (2013) X. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
- (2013) X Sui et al. Cell Death & Disease
- A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo
- (2013) Sandra Morandell et al. Cell Reports
- The Role of Mitogen-Activated Protein Kinase-Activated Protein Kinases (MAPKAPKs) in Inflammation
- (2013) Ugo Moens et al. Genes
- Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization
- (2012) L. T. Donlin et al. GENES & DEVELOPMENT
- Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
- (2012) Joshua C. Black et al. MOLECULAR CELL
- Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update
- (2012) John M. Kyriakis et al. PHYSIOLOGICAL REVIEWS
- Early Requirement of Rac1 in a Mouse Model of Pancreatic Cancer
- (2011) Irina Heid et al. GASTROENTEROLOGY
- Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2
- (2011) Mohamed Abu-Farha et al. Journal of Molecular Cell Biology
- A proteomic approach for the identification of novel lysine methyltransferase substrates
- (2011) Dan Levy et al. Epigenetics & Chromatin
- MAPKAP kinases MK2 and MK3 in inflammation: Complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin
- (2010) Natalia Ronkina et al. BIOCHEMICAL PHARMACOLOGY
- Methylation of the Retinoblastoma Tumor Suppressor by SMYD2
- (2010) Louis A. Saddic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
- (2010) John P. Morris et al. JOURNAL OF CLINICAL INVESTIGATION
- A Benzothiophene Inhibitor of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Inhibits Tumor Necrosis Factor Production and Has Oral Anti-Inflammatory Efficacy in Acute and Chronic Models of Inflammation
- (2010) R. J. Mourey et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes
- (2010) N. Ronkina et al. NUCLEIC ACIDS RESEARCH
- Cardiac Deletion of Smyd2 Is Dispensable for Mouse Heart Development
- (2010) Florian Diehl et al. PLoS One
- Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma
- (2010) P. K. Mazur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overexpression of SMYD2 relates to tumor cell proliferation and malignant outcome of esophageal squamous cell carcinoma
- (2009) Shuhei Komatsu et al. CARCINOGENESIS
- Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
- (2009) K. P. Olive et al. SCIENCE
- Complications in the Assignment of 14 and 28 Da Mass Shift Detected by Mass Spectrometry as in Vivo Methylation from Endogenous Proteins
- (2008) Sung Yun Jung et al. ANALYTICAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now