Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin
出版年份 2021 全文链接
标题
Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin
作者
关键词
-
出版物
Scientific Reports
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-05-27
DOI
10.1038/s41598-021-90219-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ablation of Acid Ceramidase Impairs Autophagy and Mitochondria Activity in Melanoma Cells
- (2021) Michele Lai et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Neuropathophysiology of Lysosomal Storage Diseases: Synaptic Dysfunction as a Starting Point for Disease Progression
- (2020) Camila Pará et al. Journal of Clinical Medicine
- Treatment of Advanced Melanoma: Past, Present and Future
- (2020) Taku Fujimura et al. Life-Basel
- Sphingolipid/Ceramide Pathways and Autophagy in the Onset and Progression of Melanoma: Novel Therapeutic Targets and Opportunities
- (2019) Michele Lai et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural basis for the activation of acid ceramidase
- (2018) Ahmad Gebai et al. Nature Communications
- Flux analysis reveals regulation of the sphingolipid network by doxorubicin in breast cancer cells
- (2018) Justin M. Snider et al. JOURNAL OF LIPID RESEARCH
- The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia
- (2017) Su-Fern Tan et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Lysophosphatidylcholine induces cytotoxicity/apoptosis and IL-8 production of human endothelial cells: Related mechanisms
- (2017) Mei-Chi Chang et al. Oncotarget
- Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency
- (2017) Ninh B. Doan et al. Oncotarget
- Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
- (2017) Michiru Nishita et al. Scientific Reports
- p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation
- (2016) Wei Jing Liu et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response
- (2016) Ruijuan Xu et al. Oncotarget
- Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells
- (2016) Feiyan Liu et al. Oncotarget
- Very long chain ceramides interfere with C16-ceramide-induced channel formation: A plausible mechanism for regulating the initiation of intrinsic apoptosis
- (2015) Johnny Stiban et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Differential Regulation of Specific Sphingolipids in Colon Cancer Cells during Staurosporine-Induced Apoptosis
- (2015) Virginia del Solar et al. CHEMISTRY & BIOLOGY
- Acid Ceramidase in Melanoma
- (2015) Natalia Realini et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Co-delivery of doxorubicin and PEGylated C16-ceramide by nanoliposomes for enhanced therapy against multidrug resistance
- (2015) Xiao Su et al. Nanomedicine
- Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik
- (2014) S. Chen et al. MOLECULAR AND CELLULAR BIOLOGY
- Altered autophagy in the mice with a deficiency of saposin A and saposin B
- (2013) Ying Sun et al. Autophagy
- Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy
- (2013) M. Selvakumaran et al. CLINICAL CANCER RESEARCH
- The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS
- (2013) Daniela Hartmann et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity
- (2013) Natalia Realini et al. Scientific Reports
- Spinal Muscular Atrophy Associated with Progressive Myoclonic Epilepsy Is Caused by Mutations in ASAH1
- (2012) Jie Zhou et al. AMERICAN JOURNAL OF HUMAN GENETICS
- C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages
- (2012) E Aflaki et al. Cell Death & Disease
- Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis
- (2011) Keisuke Kakisaka et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Acid Ceramidase Expression Modulates the Sensitivity of A375 Melanoma Cells to Dacarbazine
- (2011) Carmen Bedia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage
- (2011) Sandrine Lépine et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chain length-specific properties of ceramides
- (2011) Sabine Grösch et al. PROGRESS IN LIPID RESEARCH
- Neutrophil clearance: when the party is over, clean-up begins
- (2011) Donna L. Bratton et al. TRENDS IN IMMUNOLOGY
- Methods in Mammalian Autophagy Research
- (2010) Noboru Mizushima et al. CELL
- Pharmacokinetic evaluation of doxorubicin plasma levels in normal and overweight patients with breast cancer and simulation of dose adjustment by different indexes of body mass
- (2010) Deise Raquel Barpe et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Alkaline Ceramidase 3 (ACER3) Hydrolyzes Unsaturated Long-chain Ceramides, and Its Down-regulation Inhibits Both Cell Proliferation and Apoptosis
- (2010) Wei Hu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide
- (2010) L S Turner et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Ceramide synthases and ceramide levels are increased in breast cancer tissue
- (2009) Susanne Schiffmann et al. CARCINOGENESIS
- Life and death partners: apoptosis, autophagy and the cross-talk between them
- (2009) A Eisenberg-Lerner et al. CELL DEATH AND DIFFERENTIATION
- Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy
- (2008) Sophie Pattingre et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Acid Ceramidase Upregulation in Prostate Cancer Cells Confers Resistance to Radiation: AC Inhibition, a Potential Radiosensitizer
- (2008) Ayman EM Mahdy et al. MOLECULAR THERAPY
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Acid ceramidase inhibition: a novel target for cancer therapy
- (2007) Xiang Liu Frontiers in Bioscience-Landmark
- Upregulation of the Human Alkaline Ceramidase 1 and Acid Ceramidase Mediates Calcium-Induced Differentiation of Epidermal Keratinocytes
- (2007) Wei Sun et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation