Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

(2014) Ugur Akar et al.   Autophagy

Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism

(2011) N Hagen et al.   CELL DEATH AND DIFFERENTIATION

The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner

(2011) Ashok Kumar et al.   CELLULAR SIGNALLING

Control of basal autophagy by calpain1 mediated cleavage of ATG5

(2010) Hong-Guang Xia et al.   Autophagy

Mechanism of Autophagy to Apoptosis Switch Triggered in Prostate Cancer Cells by Antitumor Cytokine Melanoma Differentiation-Associated Gene 7/Interleukin-24

(2010) Sujit K. Bhutia et al.   CANCER RESEARCH

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy

(2010) S Lépine et al.   CELL DEATH AND DIFFERENTIATION

Doxycycline suppresses doxorubicin-induced oxidative stress and cellular apoptosis in mouse hearts

(2010) Hui-Chin Lai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protein Quality Control in the Cytosol and the Endoplasmic Reticulum: Brothers in Arms

(2010) Alexander Buchberger et al.   MOLECULAR CELL

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition

(2010) C Ji et al.   ONCOGENE

Doxorubicin-induced apoptosis in germinal vesicle (GV) oocytes☆

(2010) Hadas Bar-Joseph et al.   REPRODUCTIVE TOXICOLOGY

Safingol (l-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

(2009) Jesse Coward et al.   Autophagy

PARP-1 is involved in autophagy induced by DNA damage

(2009) José Antonio Muñoz-Gámez et al.   Autophagy

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response

(2009) Stefka D. Spassieva et al.   BIOCHEMICAL JOURNAL

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways

(2009) Can E. Senkal et al.   FASEB JOURNAL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase

(2009) V. Menuz et al.   SCIENCE

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE

DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death

(2008) D Gozuacik et al.   CELL DEATH AND DIFFERENTIATION

A role for ceramide in driving cancer cell resistance to doxorubicin

(2008) Yong-Yu Liu et al.   FASEB JOURNAL

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY

The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells

(2008) D-D Li et al.   ONCOGENE

Ceramide starves cells to death by downregulating nutrient transporter proteins

(2008) G. G. Guenther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA