Arecanut (Areca catechu L.) seed polyphenol improves osteoporosis via gut-serotonin mediated Wnt/β-catenin pathway in ovariectomized rats

Arecanut (Areca catechu L.) Seed Polyphenol-Ameliorated Osteoporosis by Altering Gut Microbiome via LYZ and the Immune System in Estrogen-Deficient Rats

(2021) Fengfeng Mei et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Tilapia head glycolipids protect mice against dextran sulfate sodium-induced colitis by ameliorating the gut barrier and suppressing NF-kappa B signaling pathway

(2021) Zhipeng Gu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis

(2020) Jiao Li et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Collagen Peptides Isolated from Salmo salar and Tilapia nilotica Skin Accelerate Wound Healing by Altering Cutaneous Microbiome Colonization via Upregulated NOD2 and BD14

(2020) Fengfeng Mei et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Overexpression of Fam20C in osteoblast in vivo leads to increased cortical bone formation and osteoclastic bone resorption

(2020) Katsutoshi Hirose et al.   BONE

General synthesis of unnatural 4-, 5-, 6-, and 7-bromo-d-tryptophans by means of a regioselective indole alkylation

(2020) Francesca Bartoccini et al.   TETRAHEDRON LETTERS

Fish-oil supplementation decreases Indoleamine-2,3-Dioxygenase expression and increases hippocampal serotonin levels in the LPS depression model

(2020) Bruno Carabelli et al.   BEHAVIOURAL BRAIN RESEARCH

G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development

(2020) Hisashi Ideno et al.   BONE

Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling

(2020) Shuo Chen et al.   Cell Reports

The effects of taxifolin on alveolar bone in experimental periodontitis in rats

(2020) Aysan Lektemur Alpan et al.   ARCHIVES OF ORAL BIOLOGY

Bone metabolism regulation: Implications for the treatment of bone diseases

(2020) Danqi Yao et al.   BIOMEDICINE & PHARMACOTHERAPY

Getting Warmer: Following One’s Gut to Build Bone

(2020) Jameel Iqbal et al.   Cell Metabolism

Comparative biochemical and transcriptome analysis provides insights into the regulatory mechanism of striped leaf albinism in arecanut (Areca catechu L.)

(2020) Jia Li et al.   INDUSTRIAL CROPS AND PRODUCTS

Morinda citrifolia L. leaves extracts obtained by traditional and eco-friendly extraction solvents: Relation between phenolic compositions and biological properties by multivariate analysis

(2020) Huilan Zhu et al.   INDUSTRIAL CROPS AND PRODUCTS

Deep eutectic solvent-based ultrasonic-assisted extraction of phenolic compounds from Moringa oleifera L. leaves: Optimization, comparison and antioxidant activity

(2020) Lingfeng Wu et al.   SEPARATION AND PURIFICATION TECHNOLOGY

OPG Production Matters Where It Happened

(2020) Masayuki Tsukasaki et al.   Cell Reports

Effect of a high-collagen peptide diet on the gut microbiota and short-chain fatty acid metabolism

(2020) Fengfeng Mei et al.   Journal of Functional Foods

The impact of glucocorticoids and statins on sleep quality

(2020) Bartosz Szmyd et al.   SLEEP MEDICINE REVIEWS

Metabolomics profiling provides valuable insights into the underlying mechanisms of Morinda officinalis on protecting glucocorticoid-induced osteoporosis

(2019) Tianshuang Xia et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Polydatin promotes the osteogenic differentiation of human bone mesenchymal stem cells by activating the BMP2-Wnt/β-catenin signaling pathway

(2019) Xiao-Jun Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibitory action of thymol on fecal microbial activity in Tamandua tetradactyla and its effect on glucocorticoid metabolite measurement

(2019) Micaela B. Ruiz et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Safety investigation of Pulsatilla chinensis saponins from chronic metabonomic study of serum biomedical changes in oral treated rat

(2019) Yonggui Song et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nutritional facets of osteoporosis management: Can probiotics help?

(2019) Julien Paccou   JOINT BONE SPINE

IFN-γ inhibits 5-HT-induced melanin biosynthesis via downregulation of 5-HT receptors in vivo/in vitro

(2019) Minxuan Cai et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Focus on the essentials: tryptophan metabolism and the microbiome-gut-brain axis

(2019) Cassandra Elise Gheorghe et al.   CURRENT OPINION IN PHARMACOLOGY

Metabonomic analysis in investigating the anti-osteoporotic effect of sialoglycoprotein isolated from eggs of carassius auratus on ovariectomized mice

(2019) Qiping Zhan et al.   Journal of Functional Foods

Ferulic acid, a natural polyphenol, protects against osteoporosis by activating SIRT1 and NF-κB in neonatal rats with glucocorticoid-induced osteoporosis

(2019) Tingting Hou et al.   BIOMEDICINE & PHARMACOTHERAPY

Bone morphogenetic protein 2 induces the activation of WNT/β-catenin signaling and human trophoblast invasion through up-regulating BAMBI

(2019) Hong-Jin Zhao et al.   CELLULAR SIGNALLING

Intrathecal administration of SRT1720 relieves bone cancer pain by inhibiting the CREB/CRTC1 signalling pathway

(2019) Chengwei Yang et al.   NEUROSCIENCE LETTERS

Role of nutritional vitamin D in osteoporosis treatment

(2018) Yi-Chou Hou et al.   CLINICA CHIMICA ACTA

Evaluation of 13-week repeated oral dose toxicity of Areca catechu in F344/N rats

(2018) Hyun-Ji Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Emulsions as delivery systems for gamma and delta tocotrienols: Formation, properties and simulated gastrointestinal fate

(2018) Fei Xu et al.   FOOD RESEARCH INTERNATIONAL

UPLC/Q-TOF-MS-based metabolomics study of the anti-osteoporosis effects of Achyranthes bidentata polysaccharides in ovariectomized rats

(2018) Mengliu Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Emerging concepts in the epidemiology, pathophysiology, and clinical care of osteoporosis across the menopausal transition

(2018) Daria Lizneva et al.   MATRIX BIOLOGY

GUT-DERIVED Serotonin CONTRIBUTES to Bone Deficits in Colitis

(2018) B. Lavoie et al.   PHARMACOLOGICAL RESEARCH

Serotonin in stem cell based-dental repair and bone formation: A review

(2018) Anne Baudry et al.   BIOCHIMIE

Isolation, purification and the anti-hypertensive effect of a novel angiotensin I-converting enzyme (ACE) inhibitory peptide from Ruditapes philippinarum fermented with Bacillus natto

(2018) Yingyun Chen et al.   Food & Function

A Metabolomics Study on the Bone Protective Effects of a Lignan-Rich Fraction From Sambucus Williamsii Ramulus in Aged Rats

(2018) Hui-Hui Xiao et al.   Frontiers in Pharmacology

BDNF mediates the protective effects of scopolamine in reserpine-induced depression-like behaviors via up-regulation of 5-HTT and TPH1

(2018) Hanjie Yu et al.   PSYCHIATRY RESEARCH

A summary of the influence of exogenous estrogen administration across the lifespan on the GH/IGF-1 axis and implications for bone health

(2017) Emily A. Southmayd et al.   GROWTH HORMONE & IGF RESEARCH

Trace level determination of 5-hydroxytryptamine and its related indoles in amniotic fluid by gas chromatography–mass spectrometry

(2017) Hongmei Shi et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The use of high-dose estrogens for the treatment of breast cancer

(2017) Herjan J.T. Coelingh Bennink et al.   MATURITAS

Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression

(2016) Hua Chen et al.   Redox Biology

Serotonin (5-HT) inhibits Factor XIII-A-mediated plasma fibronectin matrix assembly and crosslinking in osteoblast cultures via direct competition with transamidation

(2015) Cui Cui et al.   BONE

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

LRP5 Regulates Human Body Fat Distribution by Modulating Adipose Progenitor Biology in a Dose- and Depot-Specific Fashion

(2015) Nellie Y. Loh et al.   Cell Metabolism

The role of polyphenols on bone metabolism in osteoporosis

(2015) Luka Đudarić et al.   FOOD RESEARCH INTERNATIONAL

Areca catechu L. (Arecaceae): A review of its traditional uses, botany, phytochemistry, pharmacology and toxicology

(2015) Wei Peng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Smad4 mediated BMP2 signal is essential for the regulation of GATA4 and Nkx2.5 by affecting the histone H3 acetylation in H9c2 cells

(2014) Lina Si et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lrp5 regulation of bone mass and serotonin synthesis in the gut

(2014) Aruna Kode et al.   NATURE MEDICINE

No mutations in the serotonin related TPH1 and HTR1B genes in patients with monogenic sclerosing bone disorders

(2013) Eveline Boudin et al.   BONE

Metabonomic profiling in studying anti-osteoporosis effects of strontium fructose 1,6-diphosphate on estrogen deficiency-induced osteoporosis in rats by GC/TOF-MS

(2013) Bo Ma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts

(2012) Rongrong Zhang et al.   BONE

Potential analgesic, anti-inflammatory and antioxidant activities of hydroalcoholic extract of Areca catechu L. nut

(2010) Amol M. Bhandare et al.   FOOD AND CHEMICAL TOXICOLOGY

The two faces of serotonin in bone biology

(2010) Patricia Ducy et al.   JOURNAL OF CELL BIOLOGY

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis

(2010) Vijay K Yadav et al.   NATURE MEDICINE

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

(2010) M. Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis

(2010) Miriam Bellido et al.   ARTHRITIS RESEARCH & THERAPY

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

(2008) Vijay K. Yadav et al.   CELL