Plant immune networks

A five-transgene cassette confers broad-spectrum resistance to a fungal rust pathogen in wheat

(2021) Ming Luo et al.   NATURE BIOTECHNOLOGY

Perception of a divergent family of phytocytokines by the Arabidopsis receptor kinase MIK2

(2021) Jack Rhodes et al.   Nature Communications

Salicylic Acid: Biosynthesis and Signaling

(2021) Yujun Peng et al.   Annual Review of Plant Biology

The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling

(2021) Guozhi Bi et al.   CELL

Channeling plant immunity

(2021) Bruno Pok Man Ngou et al.   CELL

Plant immunity: Crosstalk between plant immune receptors

(2021) Marta Bjornson et al.   CURRENT BIOLOGY

PTI-ETI crosstalk: an integrative view of plant immunity

(2021) Minhang Yuan et al.   CURRENT OPINION IN PLANT BIOLOGY

Metabolic regulation of systemic acquired resistance

(2021) Jürgen Zeier   CURRENT OPINION IN PLANT BIOLOGY

The EDS1–PAD4–ADR1 node mediates Arabidopsis pattern-triggered immunity

(2021) Rory N. Pruitt et al.   NATURE

Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels

(2021) Pierre Jacob et al.   SCIENCE

Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

(2021) Xinhua Sun et al.   Nature Communications

Plant pathogens convergently evolved to counteract redundant nodes of an NLR immune receptor network

(2021) Lida Derevnina et al.   PLOS BIOLOGY

Co-incidence of Damage and Microbial Patterns Controls Localized Immune Responses in Roots

(2020) Feng Zhou et al.   CELL

Atypical Resistance Protein RPW8/HR Triggers Oligomerization of the NLR Immune Receptor RPP7 and Autoimmunity

(2020) Lei Li et al.   Cell Host & Microbe

Estradiol-inducible AvrRps4 expression reveals distinct properties of TIR-NLR-mediated effector-triggered immunity

(2020) Bruno Pok Man Ngou et al.   JOURNAL OF EXPERIMENTAL BOTANY

Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis

(2020) Feihua Wu et al.   NATURE

High‐resolution expression profiling of selected gene sets during plant immune activation

(2020) Pingtao Ding et al.   PLANT BIOTECHNOLOGY JOURNAL

The pan-genome effector-triggered immunity landscape of a host-pathogen interaction

(2020) Bradley Laflamme et al.   SCIENCE

Stories of Salicylic Acid: A Plant Defense Hormone

(2020) Pingtao Ding et al.   TRENDS IN PLANT SCIENCE

Origins and Immunity Networking Functions of EDS1 Family Proteins

(2020) Dmitry Lapin et al.   Annual Review of Phytopathology

Plant NLRs get by with a little help from their friends

(2020) Joanna M Feehan et al.   CURRENT OPINION IN PLANT BIOLOGY

Extensive signal integration by the phytohormone protein network

(2020) Melina Altmann et al.   NATURE

Structural basis of salicylic acid perception by Arabidopsis NPR proteins

(2020) Wei Wang et al.   NATURE

Precision transcriptomics of viral foci reveals spatial regulation of immune‐signaling genes and identifies RBOHD as an important player in the incompatible interaction between potato virus Y and potato

(2020) Tjaša Lukan et al.   PLANT JOURNAL

Formation of NPR1 Condensates Promotes Cell Survival during the Plant Immune Response

(2020) Raul Zavaliev et al.   CELL

Discovery of a Family of Mixed Lineage Kinase Domain-like Proteins in Plants and Their Role in Innate Immune Signaling

(2020) Lisa K. Mahdi et al.   Cell Host & Microbe

The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity

(2020) Kathrin Thor et al.   NATURE

Quinone perception in plants via leucine-rich-repeat receptor-like kinases

(2020) Anuphon Laohavisit et al.   NATURE

A receptor‐like protein from Nicotiana benthamiana mediates VmE02 PAMP‐triggered immunity

(2020) Jiajun Nie et al.   NEW PHYTOLOGIST

Diverse Roles of the Salicylic Acid Receptors NPR1 and NPR3/NPR4 in Plant Immunity

(2020) Yanan Liu et al.   PLANT CELL

Two unequally redundant "helper" immune receptor families mediate Arabidopsis thaliana intracellular "sensor" immune receptor functions

(2020) Svenja C. Saile et al.   PLOS BIOLOGY

The Arabidopsis leucine‐rich repeat receptor‐like kinase MIK2 is a crucial component of early immune responses to a fungal‐derived elicitor

(2020) Alexander D. Coleman et al.   NEW PHYTOLOGIST

Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme

(2020) Shoucai Ma et al.   SCIENCE

Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ

(2020) Raoul Martin et al.   SCIENCE

Signaling Crosstalk between Salicylic Acid and Ethylene/Jasmonate in Plant Defense: Do We Understand What They Are Whispering?

(2019) Ning Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Ca2+ Channel CNGC19 Regulates Arabidopsis defense against Spodoptera Herbivory

(2019) Mukesh Kumar Meena et al.   PLANT CELL

Biosynthesis and secretion of the microbial sulfated peptide RaxX and binding to the rice XA21 immune receptor

(2019) Dee Dee Luu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution and structure of a plant NLR resistosome conferring immunity

(2019) Jizong Wang et al.   SCIENCE

A calmodulin-gated calcium channel links pathogen patterns to plant immunity

(2019) Wang Tian et al.   NATURE

Mechanisms of RALF peptide perception by a heterotypic receptor complex

(2019) Yu Xiao et al.   NATURE

An EDS1-SAG101 Complex is Essential for TNL-mediated Immunity in Nicotiana benthamiana

(2019) Johannes Gantner et al.   PLANT CELL

A coevolved EDS1-SAG101-NRG1 module mediates cell death signaling by TIR-domain immune receptors

(2019) Dmitry Lapin et al.   PLANT CELL

Isochorismate-derived biosynthesis of the plant stress hormone salicylic acid

(2019) Dmitrij Rekhter et al.   SCIENCE

RPW8/HR repeats control NLR activation in Arabidopsis thaliana

(2019) Cristina A. Barragan et al.   PLoS Genetics

NLR singletons, pairs, and networks: evolution, assembly, and regulation of the intracellular immunoreceptor circuitry of plants

(2019) Hiroaki Adachi et al.   CURRENT OPINION IN PLANT BIOLOGY

TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death

(2019) Li Wan et al.   SCIENCE

NAD+ cleavage activity by animal and plant TIR domains in cell death pathways

(2019) Shane Horsefield et al.   SCIENCE

The Receptor Kinases BAK1/SERK4 Regulate Ca2+ Channel-Mediated Cellular Homeostasis for Cell Death Containment

(2019) Xiao Yu et al.   CURRENT BIOLOGY

The receptor-like kinase NIK1 targets FLS2/BAK1 immune complex and inversely modulates antiviral and antibacterial immunity

(2019) Bo Li et al.   Nature Communications

An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species

(2019) Hiroaki Adachi et al.   eLife

Cross-Microbial Protection via Priming a Conserved Immune Co-Receptor through Juxtamembrane Phosphorylation in Plants

(2019) Ben-Qiang Gong et al.   Cell Host & Microbe

PBS3 and EPS1 Complete Salicylic Acid Biosynthesis from Isochorismate in Arabidopsis

(2019) Michael P. Torrens-Spence et al.   Molecular Plant

Flavin Monooxygenase-Generated N-Hydroxypipecolic Acid Is a Critical Element of Plant Systemic Immunity

(2018) Michael Hartmann et al.   CELL

Opposite Roles of Salicylic Acid Receptors NPR1 and NPR3/NPR4 in Transcriptional Regulation of Plant Immunity

(2018) Yuli Ding et al.   CELL

N-hydroxy-pipecolic acid is a mobile metabolite that induces systemic disease resistance inArabidopsis

(2018) Yun-Chu Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor networks underpin plant immunity

(2018) Chih-Hang Wu et al.   SCIENCE

Active photosynthetic inhibition mediated by MPK3/MPK6 is critical to effector-triggered immunity

(2018) Jianbin Su et al.   PLOS BIOLOGY

An extracellular network of Arabidopsis leucine-rich repeat receptor kinases

(2018) Elwira Smakowska-Luzan et al.   NATURE

Using forward genetics in Nicotiana benthamiana to uncover the immune signaling pathway mediating recognition of the Xanthomonas perforans effector XopJ4

(2018) Alex Schultink et al.   NEW PHYTOLOGIST

Salicylic Acid: A Double-Edged Sword for Programed Cell Death in Plants

(2018) Ana Radojičić et al.   Frontiers in Plant Science

Quantitative phosphoproteomic analysis reveals common regulatory mechanisms between effector- and PAMP-triggered immunity in plants

(2018) Yasuhiro Kadota et al.   NEW PHYTOLOGIST

Differential regulation of TNL-mediated immune signaling by redundant helper CNLs

(2018) Zhongshou Wu et al.   NEW PHYTOLOGIST

Diverse NLR immune receptors activate defence via the RPW8-NLR NRG1

(2018) Baptiste Castel et al.   NEW PHYTOLOGIST

Stacking three late blight resistance genes from wild species directly into African highland potato varieties confers complete field resistance to local blight races

(2018) Marc Ghislain et al.   PLANT BIOTECHNOLOGY JOURNAL

NPR1 paralogs of Arabidopsis and their role in salicylic acid perception

(2018) María José Castelló et al.   PLoS One

The Arabidopsis Leucine-Rich Repeat Receptor Kinase BIR3 Negatively Regulates BAK1 Receptor Complex Formation and Stabilizes BAK1

(2017) Julia Imkampe et al.   PLANT CELL

NLR network mediates immunity to diverse plant pathogens

(2017) Chih-Hang Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling

(2017) Martin Stegmann et al.   SCIENCE

TNL-mediated immunity inArabidopsisrequires complex regulation of the redundantADR1gene family

(2016) Oliver Xiaoou Dong et al.   NEW PHYTOLOGIST

Characterization of a Pipecolic Acid Biosynthesis Pathway Required for Systemic Acquired Resistance

(2016) Pingtao Ding et al.   PLANT CELL

NbCSPR underlies age-dependent immune responses to bacterial cold shock protein inNicotiana benthamiana

(2016) Isabel M. L. Saur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis

(2016) Asen Daskalov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular innate immune surveillance devices in plants and animals

(2016) J. D. G. Jones et al.   SCIENCE

Salicylic acid receptors activate jasmonic acid signalling through a non-canonical pathway to promote effector-triggered immunity

(2016) Lijing Liu et al.   Nature Communications

A Plant Immune Receptor Detects Pathogen Effectors that Target WRKY Transcription Factors

(2015) Panagiotis F. Sarris et al.   CELL

The Decoy Substrate of a Pathogen Effector and a Pseudokinase Specify Pathogen-Induced Modified-Self Recognition and Immunity in Plants

(2015) Guoxun Wang et al.   Cell Host & Microbe

Multilayered Regulation of Ethylene Induction Plays a Positive Role in Arabidopsis Resistance againstPseudomonas syringae

(2015) Rongxia Guan et al.   PLANT PHYSIOLOGY

Two linked pairs of Arabidopsis TNL resistance genes independently confer recognition of bacterial effector AvrRps4

(2015) Simon B. Saucet et al.   Nature Communications

ChIP-seq reveals broad roles of SARD1 and CBP60g in regulating plant immunity

(2015) Tongjun Sun et al.   Nature Communications

An RLP23–SOBIR1–BAK1 complex mediates NLP-triggered immunity

(2015) Isabell Albert et al.   Nature Plants

The rice immune receptor XA21 recognizes a tyrosine-sulfated protein from a Gram-negative bacterium

(2015) R. N. Pruitt et al.   Science Advances

The FLS2-Associated Kinase BIK1 Directly Phosphorylates the NADPH Oxidase RbohD to Control Plant Immunity

(2014) Lei Li et al.   Cell Host & Microbe

The Leucine-Rich Repeat Receptor Kinase BIR2 Is a Negative Regulator of BAK1 in Plant Immunity

(2014) Thierry Halter et al.   CURRENT BIOLOGY

Plant PRRs and the Activation of Innate Immune Signaling

(2014) Alberto P. Macho et al.   MOLECULAR CELL

Direct Regulation of the NADPH Oxidase RBOHD by the PRR-Associated Kinase BIK1 during Plant Immunity

(2014) Yasuhiro Kadota et al.   MOLECULAR CELL

Elevating crop disease resistance with cloned genes

(2014) J. D. G. Jones et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Salicylic Acid Regulates Arabidopsis Microbial Pattern Receptor Kinase Levels and Signaling

(2014) C. Tateda et al.   PLANT CELL

The Activated SA and JA Signaling Pathways Have an Influence on flg22-Triggered Oxidative Burst and Callose Deposition

(2014) So Young Yi et al.   PLoS One

Plant pattern-recognition receptors

(2014) Cyril Zipfel   TRENDS IN IMMUNOLOGY

The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1

(2014) Yangrong Cao et al.   eLife

Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity

(2013) Stephan Wagner et al.   Cell Host & Microbe

Arabidopsis RECEPTOR-LIKE PROTEIN30 and Receptor-Like Kinase SUPPRESSOR OF BIR1-1/EVERSHED Mediate Innate Immunity to Necrotrophic Fungi

(2013) W. Zhang et al.   PLANT CELL

Receptor-like kinase SOBIR1/EVR interacts with receptor-like proteins in plant immunity against fungal infection

(2013) T. W. H. Liebrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for flg22-Induced Activation of the Arabidopsis FLS2-BAK1 Immune Complex

(2013) Y. Sun et al.   SCIENCE

NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants

(2012) Zheng Qing Fu et al.   NATURE

Pipecolic Acid, an Endogenous Mediator of Defense Amplification and Priming, Is a Critical Regulator of Inducible Plant Immunity

(2012) H. Navarova et al.   PLANT CELL

Linking ligand perception by PEPR pattern recognition receptors to cytosolic Ca2+ elevation and downstream immune signaling in plants

(2012) Y. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity

(2011) Steffen Rietz et al.   NEW PHYTOLOGIST

Expanded functions for a family of plant intracellular immune receptors beyond specific recognition of pathogen effectors

(2011) V. Bonardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis lysin-motif proteins LYM1 LYM3 CERK1 mediate bacterial peptidoglycan sensing and immunity to bacterial infection

(2011) R. Willmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor-like Cytoplasmic Kinases Integrate Signaling from Multiple Plant Immune Receptors and Are Targeted by a Pseudomonas syringae Effector

(2010) Jie Zhang et al.   Cell Host & Microbe

Activation of an Arabidopsis Resistance Protein Is Specified by the in Planta Association of Its Leucine-Rich Repeat Domain with the Cognate Oomycete Effector

(2010) K. V. Krasileva et al.   PLANT CELL

Control of salicylic acid synthesis and systemic acquired resistance by two members of a plant-specific family of transcription factors

(2010) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Cell Death and Innate Immunity by Two Receptor-like Kinases in Arabidopsis

(2009) Minghui Gao et al.   Cell Host & Microbe

Resistance and biomass in Arabidopsis: a new model for Salicylic Acid perception

(2009) Juan V. Canet et al.   PLANT BIOTECHNOLOGY JOURNAL

Mitogen-Activated Protein Kinases 3 and 6 Are Required for Full Priming of Stress Responses in Arabidopsis thaliana

(2009) G. J.M. Beckers et al.   PLANT CELL

RRS1andRPS4provide a dualResistance-gene system against fungal and bacterial pathogens

(2009) Mari Narusaka et al.   PLANT JOURNAL

A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity

(2009) D. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis CaM Binding Protein CBP60g Contributes to MAMP-Induced SA Accumulation and Is Involved in Disease Resistance against Pseudomonas syringae

(2009) Lin Wang et al.   PLoS Pathogens

Bacterial Effectors Target the Common Signaling Partner BAK1 to Disrupt Multiple MAMP Receptor-Signaling Complexes and Impede Plant Immunity

(2008) Libo Shan et al.   Cell Host & Microbe

DELLAs Control Plant Immune Responses by Modulating the Balance of Jasmonic Acid and Salicylic Acid Signaling

(2008) Lionel Navarro et al.   CURRENT BIOLOGY

From Guard to Decoy: A New Model for Perception of Plant Pathogen Effectors

(2008) R. A.L. van der Hoorn et al.   PLANT CELL

An important role of a BAHD acyl transferase-like protein in plant innate immunity

(2008) Zuyu Zheng et al.   PLANT JOURNAL

ThePseudomonas syringaetype III effector AvrRpm1 induces significant defenses by activating the Arabidopsis nucleotide-binding leucine-rich repeat protein RPS2

(2008) Min Gab Kim et al.   PLANT JOURNAL

Cross Talk in Defense Signaling

(2008) A. Koornneef et al.   PLANT PHYSIOLOGY