Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

Evolution of Plant NLRs: From Natural History to Precise Modifications

(2020) Janina Tamborski et al.   Annual Review of Plant Biology

Origins and Immunity Networking Functions of EDS1 Family Proteins

(2020) Dmitry Lapin et al.   Annual Review of Phytopathology

Induced proximity of a TIR signaling domain on a plant-mammalian NLR chimera activates defense in plants

(2020) Zane Duxbury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation of NPR1 Condensates Promotes Cell Survival during the Plant Immune Response

(2020) Raul Zavaliev et al.   CELL

Discovery of a Family of Mixed Lineage Kinase Domain-like Proteins in Plants and Their Role in Innate Immune Signaling

(2020) Lisa K. Mahdi et al.   Cell Host & Microbe

Two unequally redundant "helper" immune receptor families mediate Arabidopsis thaliana intracellular "sensor" immune receptor functions

(2020) Svenja C. Saile et al.   PLOS BIOLOGY

Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme

(2020) Shoucai Ma et al.   SCIENCE

Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ

(2020) Raoul Martin et al.   SCIENCE

An EDS1 heterodimer signalling surface enforces timely reprogramming of immunity genes in Arabidopsis

(2019) Deepak D. Bhandari et al.   Nature Communications

Reconstitution and structure of a plant NLR resistosome conferring immunity

(2019) Jizong Wang et al.   SCIENCE

An EDS1-SAG101 Complex is Essential for TNL-mediated Immunity in Nicotiana benthamiana

(2019) Johannes Gantner et al.   PLANT CELL

A coevolved EDS1-SAG101-NRG1 module mediates cell death signaling by TIR-domain immune receptors

(2019) Dmitry Lapin et al.   PLANT CELL

An artificial immune and incremental learning inspired novel framework for performance pattern identification of complex electromechanical systems

(2019) RongXi Wang et al.   Science China-Technological Sciences

The Plant “Resistosome”: Structural Insights into Immune Signaling

(2019) Hayden Burdett et al.   Cell Host & Microbe

Help wanted: helper NLRs and plant immune responses

(2019) Lance M Jubic et al.   CURRENT OPINION IN PLANT BIOLOGY

Arabidopsis immunity regulator EDS1 in a PAD4/SAG101-unbound form is a monomer with an inherently inactive conformation

(2019) Martin Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death

(2019) Li Wan et al.   SCIENCE

NAD+ cleavage activity by animal and plant TIR domains in cell death pathways

(2019) Shane Horsefield et al.   SCIENCE

Structural, Functional, and Genomic Diversity of Plant NLR Proteins: An Evolved Resource for Rational Engineering of Plant Immunity

(2018) Freddy Monteiro et al.   Annual Review of Phytopathology

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

The Defense Phytohormone Signaling Network Enables Rapid, High-Amplitude Transcriptional Reprogramming during Effector-Triggered Immunity

(2018) Akira Mine et al.   PLANT CELL

Peripheral infrastructure vectors and an extended set of plant parts for the Modular Cloning system

(2018) Johannes Gantner et al.   PLoS One

Modular Study of the Type III Effector Repertoire in Pseudomonas syringae pv. tomato DC3000 Reveals a Matrix of Effector Interplay in Pathogenesis

(2018) Hai-Lei Wei et al.   Cell Reports

Differential regulation of TNL-mediated immune signaling by redundant helper CNLs

(2018) Zhongshou Wu et al.   NEW PHYTOLOGIST

Diverse NLR immune receptors activate defence via the RPW8-NLR NRG1

(2018) Baptiste Castel et al.   NEW PHYTOLOGIST

NRG1 functions downstream of EDS1 to regulate TIR-NLR-mediated plant immunity in Nicotiana benthamiana

(2018) Tiancong Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roq1 mediates recognition of the Xanthomonas and Pseudomonas effector proteins XopQ and HopQ1

(2017) Alex Schultink et al.   PLANT JOURNAL

Signaling from the plasma-membrane localized plant immune receptor RPM1 requires self-association of the full-length protein

(2017) Farid El Kasmi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NLR network mediates immunity to diverse plant pathogens

(2017) Chih-Hang Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A core function of EDS1 with PAD4 is to protect the salicylic acid defense sector in Arabidopsis immunity

(2016) Haitao Cui et al.   NEW PHYTOLOGIST

Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis

(2016) Asen Daskalov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular innate immune surveillance devices in plants and animals

(2016) J. D. G. Jones et al.   SCIENCE

Effector-Triggered Immunity: From Pathogen Perception to Robust Defense

(2015) Haitao Cui et al.   Annual Review of Plant Biology

Complementary activities of TELOMERE REPEAT BINDING proteins and Polycomb Group complexes in transcriptional regulation of target genes

(2015) Yue Zhou et al.   PLANT CELL

Two linked pairs of Arabidopsis TNL resistance genes independently confer recognition of bacterial effector AvrRps4

(2015) Simon B. Saucet et al.   Nature Communications

Microbial effectors target multiple steps in the salicylic acid production and signaling pathway

(2015) Shigeyuki Tanaka et al.   Frontiers in Plant Science

The plant metacaspase AtMC1 in pathogen-triggered programmed cell death and aging: functional linkage with autophagy

(2014) N S Coll et al.   CELL DEATH AND DIFFERENTIATION

The Nuclear Immune Receptor RPS4 Is Required for RRS1SLH1-Dependent Constitutive Defense Activation in Arabidopsis thaliana

(2014) Kee Hoon Sohn et al.   PLoS Genetics

Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity

(2013) Stephan Wagner et al.   Cell Host & Microbe

Genetic Requirements for Signaling from an Autoactive Plant NB-LRR Intracellular Innate Immune Receptor

(2013) Melinda Roberts et al.   PLoS Genetics

An Autoactive Mutant of the M Flax Rust Resistance Protein Has a Preference for Binding ATP, Whereas Wild-Type M Protein Binds ADP

(2011) Simon J. Williams et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Cell Death Mediated by the N-Terminal Domains of a Unique and Highly Conserved Class of NB-LRR Protein

(2011) Sarah M. Collier et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity

(2011) Steffen Rietz et al.   NEW PHYTOLOGIST

Expanded functions for a family of plant intracellular immune receptors beyond specific recognition of pathogen effectors

(2011) V. Bonardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Salicylic acid antagonism of EDS1-driven cell death is important for immune and oxidative stress responses in Arabidopsis

(2010) Marco R. Straus et al.   PLANT JOURNAL

Arabidopsis Type I Metacaspases Control Cell Death

(2010) N. S. Coll et al.   SCIENCE

Balanced Nuclear and Cytoplasmic Activities of EDS1 Are Required for a Complete Plant Innate Immune Response

(2010) Ana V. García et al.   PLoS Pathogens

Recombineering and stable integration of the Pseudomonas syringae pv. syringae 61 hrp/hrc cluster into the genome of the soil bacterium Pseudomonas fluorescens Pf0-1

(2009) William J. Thomas et al.   PLANT JOURNAL

Enhanced Disease Susceptibility 1 and Salicylic Acid Act Redundantly to Regulate Resistance Gene-Mediated Signaling

(2009) Srivathsa C. Venugopal et al.   PLoS Genetics

Network Properties of Robust Immunity in Plants

(2009) Kenichi Tsuda et al.   PLoS Genetics