Asymmetric catalytic 1,3-dipolar cycloaddition of α-diazoesters for synthesis of 1-pyrazoline-based spirochromanones and beyond

A theoretical study of inversion barriers and NMR chemical shifts of 3‐pyrazolines (2,3 ‐dihydro‐1 H ‐pyrazoles)

(2021) Ibon Alkorta et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Catalytic Asymmetric Homologation of Ketones with α-Alkyl α-Diazo Esters

(2021) Fei Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biological Evaluation of 3-Benzylidenechromanones and Their Spiropyrazolines-Based Analogues

(2020) Angelika A. Adamus-Grabicka et al.   MOLECULES

Multisubstituted pyrazole synthesis via [3 + 2] cycloaddition/rearrangement/N H insertion cascade reaction of α-diazoesters and ynones

(2020) Peng Zhao et al.   CHINESE CHEMICAL LETTERS

Feng Ligand: Privileged Chiral Ligand in Asymmetric Catalysis

(2020) Ming‐Yang Wang et al.   CHINESE JOURNAL OF CHEMISTRY

Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry

(2020) Nan Qin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chiral Spiro Phosphoric Acid-Catalyzed Friedel–Crafts Conjugate Addition/Enantioselective Protonation Reactions

(2019) Yi-Pan Li et al.   ACS Catalysis

Chiral Spiro Phosphoramide-Catalyzed Sulfa-Michael Addition/Enantioselective Protonation of Exocyclic Enones

(2019) Yi-Pan Li et al.   ORGANIC LETTERS

Chiral Amino Acids-Derived Catalysts and Ligands

(2018) Xiaohua Liu et al.   CHINESE JOURNAL OF CHEMISTRY

Chiral Nickel(II) Complex Catalyzed Enantioselective Doyle–Kirmse Reaction of α-Diazo Pyrazoleamides

(2018) Xiaobin Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of spiro-4H-pyrazole-oxindoles and fused 1H-pyrazoles via divergent, thermally induced tandem cyclization/migration of alkyne-tethered diazo compounds

(2018) Cheng Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic hydrogenation of 1 and 2-pyrazoline. Isolation of pyrazolidine and process schemes

(2018) A. El Hajj et al.   Reaction Kinetics Mechanisms and Catalysis

Chiral Lewis acid-catalyzed enantioselective cyclopropanation and C–H insertion reactions of vinyl ketones with α-diazoesters

(2018) Peng Zhao et al.   CHEMICAL COMMUNICATIONS

One-Pot Catalytic Enantioselective Synthesis of 2-Pyrazolines

(2018) Connor Jack Thomson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Lewis Acid Catalyzed Reactions of α-Diazoester Derivatives: Construction of Dimeric Polycyclic Compounds

(2018) Fei Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction of α-Diazoacetates and β-Trifluoromethyl Enones: A Facile Access to Multisubstituted 4-(Trifluoromethyl)pyrazolines

(2018) Yongfeng Li et al.   ORGANIC LETTERS

Review: biologically active pyrazole derivatives

(2017) Anam Ansari et al.   NEW JOURNAL OF CHEMISTRY

Enantioselective 1,3-Dipolar Cycloaddition of Methyleneindolinones with α-Diazomethylphosphonate to Access Chiral Spiro-phosphonylpyrazoline-oxindoles Catalyzed by Tertiary Amine Thiourea and 1,5-Diazabicyclo[4.3.0]non-5-ene

(2017) Nan Huang et al.   ORGANIC LETTERS

Mechanistic study of stereoselectivity in azoalkane denitrogenations

(2017) Manabu Abe et al.   PURE AND APPLIED CHEMISTRY

Syntheses of CF 2 H-containing spirocyclopropyloxindoles from in situ generated CF 2 HCHN 2 and 3-ylideneoxindoles

(2017) Wen-Yong Han et al.   TETRAHEDRON

Chiral ligands designed in China

(2017) Yuanyuan Liu et al.   National Science Review

Functionalization of Unactivated C(sp3 )−H Bonds Using Metal-Carbene Insertion Reactions

(2016) Miguel Peña-López et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel spiropyrazolone antitumor scaffold with potent activity: Design, synthesis and structure–activity relationship

(2016) Shanchao Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The therapeutic voyage of pyrazole and its analogs: A review

(2016) Mohemmed Faraz Khan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Impact of Diradical Spin State (Singlet vs Triplet) and Structure (Puckered vs Planar) on the Photodenitrogenation Stereoselectivity of 2,3-Diazabicyclo[2.2.1]heptanes

(2016) Manabu Abe et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Rh-Catalyzed Intermolecular Reactions of α-Alkyl-α-Diazo Carbonyl Compounds with Selectivity over β-Hydride Migration

(2015) Andrew DeAngelis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Divergent Cascade Construction of Skeletally Diverse “Privileged” Pyrazole-Derived Molecular Architectures

(2015) Yongqiang Zhang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Highly enantioselective catalytic 1,3-dipolar cycloadditions of α-alkyl diazoacetates: efficient synthesis of functionalized 2-pyrazolines

(2015) Sung Il Lee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1)

(2015) Emanuele Amata et al.   TETRAHEDRON LETTERS

Copper-Catalyzed Asymmetric Formal [3 + 2] Cycloaddition of Propargylic Acetates with Hydrazines: Enantioselective Synthesis of Optically Active 2-Pyrazolines

(2015) De-Yang Zhang et al.   ACS Catalysis

Catalytic Asymmetric Intramolecular Homologation of Ketones with α-Diazoesters: Synthesis of Cyclic α-Aryl/Alkyl β-Ketoesters

(2014) Wei Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Pyrazoles Based on Functionalized Allenoates

(2014) Ilshat M. Sakhautdinov et al.   HETEROCYCLES

Interceptive [4 + 1] Annulation of in Situ Generated 1,2-Diaza-1,3-dienes with Diazo Esters: Direct Access to Substituted Mono-, Bi-, and Tricyclic 4,5-Dihydropyrazoles

(2014) Orazio A. Attanasi et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of CF3-Containing 3,3′-Cyclopropyl Spirooxindoles by Sequential [3 + 2] Cycloaddition/Ring Contraction of Ylideneoxindoles with 2,2,2-Trifluorodiazoethane

(2014) Tian-Ren Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral N,N′-dioxide ligands: synthesis, coordination chemistry and asymmetric catalysis

(2014) Xiaohua Liu et al.   Organic Chemistry Frontiers

Synthesis, characterization, cytotoxicity and antibacterial activity of an anthracenyl-linked bis(pyrazolyl)methane ligand and its zinc(II) complexes

(2013) Ban-Feng Ruan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Enantioselective Carbon Insertion into the β-Vinyl C–H Bond of Cyclic Enones

(2013) Sung Il Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Green synthesis of 1,4-dihydropyrano[2,3-c]pyrazole derivatives using maltose as biodegradable catalyst

(2013) Mehrnoosh Kangani et al.   RESEARCH ON CHEMICAL INTERMEDIATES

A Catalytic Asymmetric Ring-Expansion Reaction of Isatins and α-Alkyl-α-Diazoesters: Highly Efficient Synthesis of Functionalized 2-Quinolone Derivatives

(2012) Wei Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1,3-Dipolar Cycloaddition of Ethyl Diazoacetate with (E)-3-Arylidenechroman-4-ones. A New Access to Spirocyclopropane Derivatives

(2012) Kabula Ciamala et al.   HETEROCYCLES

Enantioselective Synthesis of Dihydropyrazoles by Formal [4+1] Cycloaddition of in Situ-Derived Azoalkenes and Sulfur Ylides

(2012) Jia-Rong Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective synthesis of bio-relevant 3,5-diaryl pyrazolines

(2012) Olivier Mahé et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

ChiralN,N′-Dioxides: New Ligands and Organocatalysts for Catalytic Asymmetric Reactions

(2011) XiaoHua Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cinchona Alkaloid-Catalyzed Enantioselective Amination of α,β-Unsaturated Ketones: An Asymmetric Approach to Δ2-Pyrazolines

(2011) Nathaniel R. Campbell et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis and antileishmanial evaluation of 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives

(2011) Maurício S. dos Santos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Guiding principles for site selective and stereoselective intermolecular C–H functionalization by donor/acceptor rhodium carbenes

(2011) Huw M. L. Davies et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Cycloaddition Reactions of Diazoesters with 2-Alkenoic Acid Derivatives Catalyzed by Binaphthyldiimine–Ni(II) complexes

(2011) Hiroyuki Suga et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Phase-Transfer Catalysis: Synthesis of Pyrazolines

(2010) Olivier Mahé et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1,3-Dipolar Cycloaddition Reactions of Vinylidenecyclopropane-Diesters with Aromatic Diazomethanes Generated in Situ

(2010) Lei Wu et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Roskamp Reaction of α-Alkyl-α-diazoesters with Aromatic Aldehydes: Highly Enantioselective Synthesis of α-Alkyl-β-keto Esters

(2010) Wei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An efficient solvent-free synthesis of NH-pyrazoles from β-dimethylaminovinylketones and hydrazine on grinding

(2010) Kelvis Longhi et al.   TETRAHEDRON LETTERS

A Catalytic Asymmetric 6 π Electrocyclization: Enantioselective Synthesis of 2-Pyrazolines

(2009) Steffen Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent development of reactions with α-diazocarbonyl compounds as nucleophiles

(2009) Yan Zhang et al.   CHEMICAL COMMUNICATIONS

Mechanically activated synthesis of 1,3,5-triaryl-2-pyrazolines by high speed ball milling

(2009) Xingyi Zhu et al.   GREEN CHEMISTRY