Outer membrane permeability: Antimicrobials and diverse nutrients bypass porins in Pseudomonas aeruginosa

Towards understanding single-channel characteristics of OccK8 purified from Pseudomonas aeruginosa

(2021) Fatma Dogan Guzel et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Fosmidomycin transport through the phosphate‐specific porins OprO and OprP of Pseudomonas aeruginosa

(2021) Claudio Piselli et al.   MOLECULAR MICROBIOLOGY

Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria

(2020) Rachael A. Mansbach et al.   Journal of Chemical Information and Modeling

Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains

(2019) Olivier Cunrath et al.   EBioMedicine

In Vivo Proteome of Pseudomonas aeruginosa in Airways of Cystic Fibrosis Patients

(2019) Xia Wu et al.   JOURNAL OF PROTEOME RESEARCH

Distinct Roles of Outer Membrane Porins in Antibiotic Resistance and Membrane Integrity in Escherichia coli

(2019) Umji Choi et al.   Frontiers in Microbiology

Permeability barriers of Gram-negative pathogens

(2019) Helen I. Zgurskaya et al.   Annals of the New York Academy of Sciences

Ceftazidime, carbapenems, or piperacillin-tazobactam as single definitive therapy for Pseudomonas aeruginosa bloodstream infection - a multi-site retrospective study

(2019) Tanya Babich et al.   CLINICAL INFECTIOUS DISEASES

Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens

(2019) Erica N. Parker et al.   Nature Microbiology

Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients

(2019) La Rosa et al.   Metabolites

Molecular characterization of the outer membrane of Pseudomonas aeruginosa

(2019) Cesar A. López et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria

(2019) Julia Vergalli et al.   NATURE REVIEWS MICROBIOLOGY

Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa

(2018) Sarah J. Cooper et al.   ACS Infectious Diseases

Getting drugs into Gram-negative bacteria: Rational rules for permeation through general porins

(2018) Silvia Acosta-Gutierrez et al.   ACS Infectious Diseases

Getting Drugs through Small Pores: Exploiting the Porins Pathway in Pseudomonas aeruginosa

(2018) Susruta Samanta et al.   ACS Infectious Diseases

Predictive compound accumulation rules yield a broad-spectrum antibiotic

(2017) Michelle F. Richter et al.   NATURE

Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram-Negative Bacteria

(2017) Ganesh Krishnamoorthy et al.   mBio

Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis

(2017) Jennifer A. Bartell et al.   Nature Communications

Dynamics and Interactions of OmpF and LPS: Influence on Pore Accessibility and Ion Permeability

(2016) Dhilon S. Patel et al.   BIOPHYSICAL JOURNAL

Copy number variability of expression plasmids determined by cell sorting and Droplet Digital PCR

(2016) Michael Jahn et al.   Microbial Cell Factories

Mutant Alleles oflptDIncrease the Permeability of Pseudomonas aeruginosa and Define Determinants of Intrinsic Resistance to Antibiotics

(2015) Carl J. Balibar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

TtOmp85, a β-Barrel Assembly Protein, Functions by Barrel Augmentation

(2015) Luisa Estrada Mallarino et al.   BIOCHEMISTRY

Toward the Rational Design of Carbapenem Uptake in Pseudomonas aeruginosa

(2015) Vincent M. Isabella et al.   CHEMISTRY & BIOLOGY

ESKAPEing the labyrinth of antibacterial discovery

(2015) Ruben Tommasi et al.   NATURE REVIEWS DRUG DISCOVERY

Fitness cost of antibiotic susceptibility during bacterial infection

(2015) Damien Roux et al.   Science Translational Medicine

OprG Harnesses the Dynamics of its Extracellular Loops to Transport Small Amino Acids across the Outer Membrane of Pseudomonas aeruginosa

(2015) Iga Kucharska et al.   STRUCTURE

Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It

(2015) Helen I. Zgurskaya et al.   ACS Infectious Diseases

The periplasmic domain of Escherichia coli outer membrane protein A can undergo a localized temperature dependent structural transition

(2014) Hiroaki Ishida et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Carboxylic Acid (Bio)Isosteres in Drug Design

(2013) Carlo Ballatore et al.   ChemMedChem

Bacterial Secretins Form Constitutively Open Pores Akin to General Porins

(2013) E. Disconzi et al.   JOURNAL OF BACTERIOLOGY

Alternative folding pathways of the major porin OprF of Pseudomonas aeruginosa

(2012) Etsuko Sugawara et al.   FEBS Journal

Substrate Specificity within a Family of Outer Membrane Carboxylate Channels

(2012) Elif Eren et al.   PLOS BIOLOGY

Genetic Determinants Involved in the Susceptibility of Pseudomonas aeruginosa to  -Lactam Antibiotics

(2010) C. Alvarez-Ortega et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

YfiBNR Mediates Cyclic di-GMP Dependent Small Colony Variant Formation and Persistence in Pseudomonas aeruginosa

(2010) Jacob G. Malone et al.   PLoS Pathogens

Genomewide Identification of Genetic Determinants of Antimicrobial Drug Resistance in Pseudomonas aeruginosa

(2009) A. Dotsch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

(2009) P. D. Lister et al.   CLINICAL MICROBIOLOGY REVIEWS

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Complex Ciprofloxacin Resistome Revealed by Screening a Pseudomonas aeruginosa Mutant Library for Altered Susceptibility

(2008) E. B. M. Breidenstein et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Outer membrane permeability and antibiotic resistance

(2008) Anne H. Delcour   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS