Replacement of Arg in the conserved N-terminal RLFDQxFG motif affects physico-chemical properties and chaperone-like activity of human small heat shock protein HspB8 (Hsp22)

The Role of HSPB8, a Component of the Chaperone-Assisted Selective Autophagy Machinery, in Cancer

(2021) Riccardo Cristofani et al.   Cells

Structural basis of substrate recognition and thermal protection by a small heat shock protein

(2021) Chuanyang Yu et al.   Nature Communications

Conditional Disorder in Small Heat-shock Proteins

(2020) T. Reid Alderson et al.   JOURNAL OF MOLECULAR BIOLOGY

Plant small heat shock proteins – evolutionary and functional diversity

(2020) Elizabeth R. Waters et al.   NEW PHYTOLOGIST

The Heterooligomerization of Human Small Heat Shock Proteins Is Controlled by Conserved Motif Located in the N-Terminal Domain

(2020) Vladislav M. Shatov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Local unfolding of the HSP27 monomer regulates chaperone activity

(2019) T. Reid Alderson et al.   Nature Communications

Mechanisms of Small Heat Shock Proteins

(2019) Maria K. Janowska et al.   Cold Spring Harbor Perspectives in Biology

Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of 'quasi-ordered' states

(2019) Amanda F Clouser et al.   eLife

Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease

(2019) Jack M. Webster et al.   Frontiers in Pharmacology

The structure and oxidation of the eye lens chaperone αA-crystallin

(2019) Christoph J. O. Kaiser et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Terminal regions confer plasticity to the tetrameric assembly of human HspB2 and HspB3

(2018) Alice R. Clark et al.   JOURNAL OF MOLECULAR BIOLOGY

The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8

(2018) Vladislav Shatov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1

(2017) Michelle Heirbaut et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

(2016) Evgeny V. Mymrikov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers

(2015) Scott P. Delbecq et al.   BIOCHEMISTRY

Small heat shock proteins: Role in cellular functions and pathology

(2015) Raman Bakthisaran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

A First Line of Stress Defense: Small Heat Shock Proteins and Their Function in Protein Homeostasis

(2015) Martin Haslbeck et al.   JOURNAL OF MOLECULAR BIOLOGY

HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy

(2014) Serena Carra et al.   Autophagy

C-terminal interactions mediate the quaternary dynamics of  B-crystallin

(2013) G. R. Hilton et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Binding determinants of the small heat shock protein, αB-crystallin: recognition of the ‘IxI’ motif

(2012) Scott P Delbecq et al.   EMBO JOURNAL

Phosphorylation by cyclic AMP-dependent protein kinase inhibits chaperone-like activity of human HSP22 in vitro

(2011) A. A. Shemetov et al.   BIOCHEMISTRY-MOSCOW

Heterooligomeric complexes of human small heat shock proteins

(2011) Evgeny V. Mymrikov et al.   CELL STRESS & CHAPERONES

Phosphorylation of human small heat shock protein HspB8 (Hsp22) by ERK1 protein kinase

(2011) Anton A. Shemetov et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

N-terminal domain of  B-crystallin provides a conformational switch for multimerization and structural heterogeneity

(2011) S. Jehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent evolution of the core domain and its flanking sequences in small heat shock proteins

(2010) Thomas Kriehuber et al.   FASEB JOURNAL

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

(2010) Arthur Laganowsky et al.   PROTEIN SCIENCE

Identification of the key structural motifs involved in HspB8/HspB6–Bag3 interaction

(2009) Margit Fuchs et al.   BIOCHEMICAL JOURNAL

HSPB7 is a SC35 speckle resident small heat shock protein

(2009) Michel J. Vos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Thermally induced structural changes of intrinsically disordered small heat shock protein Hsp22

(2009) Alexey S. Kazakov et al.   BIOPHYSICAL CHEMISTRY

The pivotal role of the β7 strand in the intersubunit contacts of different human small heat shock proteins

(2009) Evgeny V. Mymrikov et al.   CELL STRESS & CHAPERONES

Phosphorylation Dependence of Hsp27 Multimeric Size and Molecular Chaperone Function

(2009) David Hayes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of α-Crystallin Domain Dimers of αB-Crystallin and Hsp20

(2009) C. Bagnéris et al.   JOURNAL OF MOLECULAR BIOLOGY