Small-molecule approaches toward the targeting of oncogenic miRNAs: roadmap for the discovery of RNA modulators
出版年份 2016 全文链接
标题
Small-molecule approaches toward the targeting of oncogenic miRNAs: roadmap for the discovery of RNA modulators
作者
关键词
-
出版物
Future Medicinal Chemistry
Volume 8, Issue 7, Pages 803-816
出版商
Future Science, LTD
发表日期
2016-05-06
DOI
10.4155/fmc-2016-0018
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Rapid and Versatile Assay for Ago2-Mediated Cleavage by Using Branched Rolling Circle Amplification
- (2016) Marlen Hesse et al. CHEMBIOCHEM
- Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling
- (2015) Christopher L. Haga et al. ACS Chemical Biology
- Small Molecule Targeting of a MicroRNA Associated with Hepatocellular Carcinoma
- (2015) Jessica L. Childs-Disney et al. ACS Chemical Biology
- Small molecule compounds targeting miRNAs for cancer therapy
- (2015) Paloma del C. Monroig et al. ADVANCED DRUG DELIVERY REVIEWS
- Discovery of 4-benzoylamino-N-(prop-2-yn-1-yl)benzamides as novel microRNA-21 inhibitors
- (2015) Cong-shan Jiang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting
- (2015) Thi Phuong Anh Tran et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Nonconventional chemical inhibitors of microRNA: therapeutic scope
- (2015) Gopal Gunanathan Jayaraj et al. CHEMICAL COMMUNICATIONS
- Exploratory Study on the RNA-Binding Structural Motifs by Library Screening Targeting pre-miRNA-29 a
- (2015) Takeo Fukuzumi et al. CHEMISTRY-A EUROPEAN JOURNAL
- Small molecule chemical probes of microRNA function
- (2015) Sai Pradeep Velagapudi et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- A Small-Molecule Targeting the MicroRNA Binding Domain of Argonaute 2 improves the Retinoic Acid Differentiation Response of the Acute Promyelocytic Leukemia Cell Line NB4
- (2014) Silvia Masciarelli et al. ACS Chemical Biology
- High-Throughput Platform Assay Technology for the Discovery of pre-microRNA-Selective Small Molecule Probes
- (2014) Daniel A. Lorenz et al. BIOCONJUGATE CHEMISTRY
- Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor
- (2014) Sai Pradeep Velagapudi et al. CHEMICAL COMMUNICATIONS
- Anti-cancer therapeutic potential of quinazoline based small molecules via global upregulation of miRNAs
- (2014) Smita Nahar et al. CHEMICAL COMMUNICATIONS
- Development of microRNA therapeutics is coming of age
- (2014) E. van Rooij et al. EMBO Molecular Medicine
- Sequence-based design of bioactive small molecules that target precursor microRNAs
- (2014) Sai Pradeep Velagapudi et al. Nature Chemical Biology
- Therapeutic targeting of microRNAs: current status and future challenges
- (2014) Zhonghan Li et al. NATURE REVIEWS DRUG DISCOVERY
- Drug target miRNAs: chances and challenges
- (2014) Marco F. Schmidt TRENDS IN BIOTECHNOLOGY
- MicroRNA-Specific Argonaute 2 Protein Inhibitors
- (2013) Marco F. Schmidt et al. ACS Chemical Biology
- A Molecular-Beacon-Based Screen for Small Molecule Inhibitors of miRNA Maturation
- (2013) Debojit Bose et al. ACS Chemical Biology
- Targeting the Production of Oncogenic MicroRNAs with Multimodal Synthetic Small Molecules
- (2013) Duc Duy Vo et al. ACS Chemical Biology
- Molecular Mechanisms of RNA Interference
- (2013) Ross C. Wilson et al. Annual Review of Biophysics
- Perspectives in targeting miRNA function
- (2013) Christiane Schöniger et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Probing the microRNA pathway with small molecules
- (2013) Yujing Li et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Fluorescent indicator displacement assay of ligands targeting 10 microRNA precursors
- (2013) Asako Murata et al. BIOORGANIC & MEDICINAL CHEMISTRY
- AC1MMYR2, an Inhibitor of Dicer-Mediated Biogenesis of Oncomir miR-21, Reverses Epithelial-Mesenchymal Transition and Suppresses Tumor Growth and Progression
- (2013) Z. Shi et al. CANCER RESEARCH
- MicroRNA: Function, Detection, and Bioanalysis
- (2013) Haifeng Dong et al. CHEMICAL REVIEWS
- MicroRNAs and other non-coding RNAs as targets for anticancer drug development
- (2013) Hui Ling et al. NATURE REVIEWS DRUG DISCOVERY
- Ribosome-targeting antibiotics and mechanisms of bacterial resistance
- (2013) Daniel N. Wilson NATURE REVIEWS MICROBIOLOGY
- Treatment of HCV Infection by Targeting MicroRNA
- (2013) Harry L.A. Janssen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Sequence-specific inhibition of Dicer measured with a force-based microarray for RNA ligands
- (2013) Katja Limmer et al. NUCLEIC ACIDS RESEARCH
- Methods to enable the design of bioactive small molecules targeting RNA
- (2013) Matthew D. Disney et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- microRNA Involvement in Hepatocellular Carcinoma
- (2012) Massimo Negrini et al. Anti-Cancer Agents in Medicinal Chemistry
- Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules
- (2012) Asako Murata et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- microRNA involvement in human cancer
- (2012) M. V. Iorio et al. CARCINOGENESIS
- The molecular architecture of human Dicer
- (2012) Pick-Wei Lau et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Small Molecule Inhibition of RISC Loading
- (2011) Grace S. Tan et al. ACS Chemical Biology
- Recent Advances in Developing Small Molecules Targeting RNA
- (2011) Lirui Guan et al. ACS Chemical Biology
- The Tuberculosis Drug Streptomycin as a Potential Cancer Therapeutic: Inhibition of miR-21 Function by Directly Targeting Its Precursor
- (2011) Debojit Bose et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing
- (2011) Mohitosh Maiti et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A Rapid Assay for miRNA Maturation by Using Unmodified pre-miRNA
- (2011) Saskia Neubacher et al. CHEMBIOCHEM
- Antisense drug discovery and development
- (2011) Tsuyoshi Yamamoto et al. Future Medicinal Chemistry
- Defining the RNA Internal Loops Preferred by Benzimidazole Derivatives via 2D Combinatorial Screening and Computational Analysis
- (2011) Sai Pradeep Velagapudi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
- (2011) S. Melo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation and function of miRNA-21 in health and disease
- (2011) Regalla Kumarswamy et al. RNA Biology
- Structure-Activity Relationships through Sequencing (StARTS) Defines Optimal and Suboptimal RNA Motif Targets for Small Molecules
- (2010) Sai Pradeep Velagapudi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Identification of Small Molecules That Suppress MicroRNA Function and Reverse Tumorigenesis
- (2010) Koichi Watashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fluorescent Indicator Displacement Assay for Ligand−RNA Interactions
- (2010) Jinhua Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma
- (2010) Douglas D. Young et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
- (2010) Li Ma et al. NATURE BIOTECHNOLOGY
- Targeting microRNAs in cancer: rationale, strategies and challenges
- (2010) Ramiro Garzon et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting DNA base pair mismatch with artificial nucleobases. Advances and perspectives in triple helix strategy
- (2010) Vincent Malnuit et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Antibiotics that target protein synthesis
- (2010) Lisa S. McCoy et al. Wiley Interdisciplinary Reviews-RNA
- Highly Sensitive Determination of microRNA Using Target-Primed and Branched Rolling-Circle Amplification
- (2009) Yongqiang Cheng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Short and Efficient Synthesis of Alkyne-Modified Amino Glycoside Building Blocks
- (2009) Claudine M. Klemm et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer
- (2009) P. Olson et al. GENES & DEVELOPMENT
- Biological Barriers to Therapy with Antisense and siRNA Oligonucleotides
- (2009) R. Juliano et al. MOLECULAR PHARMACEUTICS
- Biogenesis of small RNAs in animals
- (2009) V. Narry Kim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efficiently identify aminoglycoside–RNA hairpin loop interactions
- (2009) Dustin J. Paul et al. NUCLEIC ACIDS RESEARCH
- Discovering ligands for a microRNA precursor with peptoid microarrays
- (2009) Sara Chirayil et al. NUCLEIC ACIDS RESEARCH
- Small-Molecule Inhibitors of MicroRNA miR-21 Function
- (2008) Kiranmai Gumireddy et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Targeting RNA with Small Molecules
- (2008) Jason R. Thomas et al. CHEMICAL REVIEWS
- Two-Dimensional Combinatorial Screening Identifies Specific Aminoglycoside−RNA Internal Loop Partners
- (2008) Matthew D. Disney et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A small molecule enhances RNA interference and promotes microRNA processing
- (2008) Ge Shan et al. NATURE BIOTECHNOLOGY
- The evolution of our thinking about microRNAs
- (2008) Victor Ambros NATURE MEDICINE
- In vitro reconstitution of the human RISC-loading complex
- (2008) I. J. MacRae et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A fluorescence probe for assaying micro RNA maturation
- (2007) Brian P. Davies et al. BIOORGANIC & MEDICINAL CHEMISTRY
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