Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor

Rational Design of Bioactive, Modularly Assembled Aminoglycosides Targeting the RNA that Causes Myotonic Dystrophy Type 1

(2012) Jessica L. Childs-Disney et al.   ACS Chemical Biology

Rationally Designed Small Molecules Targeting the RNA That Causes Myotonic Dystrophy Type 1 Are Potently Bioactive

(2012) Jessica L. Childs-Disney et al.   ACS Chemical Biology

Probing a 2-Aminobenzimidazole Library for Binding to RNA Internal Loops via Two-Dimensional Combinatorial Screening

(2012) Sai Pradeep Velagapudi et al.   ACS Chemical Biology

Recent Advances in Developing Small Molecules Targeting RNA

(2011) Lirui Guan et al.   ACS Chemical Biology

The Tuberculosis Drug Streptomycin as a Potential Cancer Therapeutic: Inhibition of miR-21 Function by Directly Targeting Its Precursor

(2011) Debojit Bose et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Defining the RNA Internal Loops Preferred by Benzimidazole Derivatives via 2D Combinatorial Screening and Computational Analysis

(2011) Sai Pradeep Velagapudi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma

(2011) L. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Activity Relationships through Sequencing (StARTS) Defines Optimal and Suboptimal RNA Motif Targets for Small Molecules

(2010) Sai Pradeep Velagapudi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma

(2010) Douglas D. Young et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

(2010) Li Ma et al.   NATURE BIOTECHNOLOGY

Rational Design of Ligands Targeting Triplet Repeating Transcripts That Cause RNA Dominant Disease: Application to Myotonic Muscular Dystrophy Type 1 and Spinocerebellar Ataxia Type 3

(2009) Alexei Pushechnikov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small-Molecule Inhibitors of MicroRNA miR-21 Function

(2008) Kiranmai Gumireddy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting RNA with Small Molecules

(2008) Jason R. Thomas et al.   CHEMICAL REVIEWS

Two-Dimensional Combinatorial Screening Identifies Specific Aminoglycoside−RNA Internal Loop Partners

(2008) Matthew D. Disney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY