RNA pull-down confocal nanoscanning (RP-CONA) detects quercetin as pri-miR-7/HuR interaction inhibitor that decreases α-synuclein levels
出版年份 2021 全文链接
标题
RNA pull-down confocal nanoscanning (RP-CONA) detects quercetin as pri-miR-7/HuR interaction inhibitor that decreases α-synuclein levels
作者
关键词
-
出版物
NUCLEIC ACIDS RESEARCH
Volume 49, Issue 11, Pages 6456-6473
出版商
Oxford University Press (OUP)
发表日期
2021-05-21
DOI
10.1093/nar/gkab484
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing
- (2021) Seungjae Lee et al. PLoS Genetics
- Understanding and targeting the disease‐related RNA binding protein human antigen R (HuR)
- (2020) Christopher W. Schultz et al. Wiley Interdisciplinary Reviews-RNA
- Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts
- (2020) Margaux Teil et al. Biomolecules
- RNA-Targeted Therapies and High-Throughput Screening Methods
- (2020) Siran Zhu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Risdiplam: First Approval
- (2020) Sohita Dhillon DRUGS
- Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM
- (2019) Nina Ripin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-Synuclein–Confocal Nanoscanning (ASYN-CONA), a Bead-Based Assay for Detecting Early-Stage α-Synuclein Aggregation
- (2019) Irene Pérez-Pi et al. ANALYTICAL CHEMISTRY
- Meta‐analyses identify differentially expressed micrornas in Parkinson's disease
- (2019) Jessica Schulz et al. ANNALS OF NEUROLOGY
- Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions
- (2019) Julia K. Nussbacher et al. NEURON
- Discovery of Small‐Molecule Modulators of Protein–RNA Interactions by Fluorescence Intensity‐Based Binding Assay
- (2019) Wan Gi Byun et al. CHEMBIOCHEM
- Structural basis of a small molecule targeting RNA for a specific splicing correction
- (2019) Sébastien Campagne et al. Nature Chemical Biology
- Altered RNA Processing in Cancer Pathogenesis and Therapy
- (2019) Esther A. Obeng et al. Cancer Discovery
- miR-7 Replacement Therapy in Parkinson’s Disease
- (2018) Ricardo Titze-de-Almeida et al. CURRENT GENE THERAPY
- Regulation of primary microRNA processing
- (2018) Antoine Creugny et al. FEBS LETTERS
- Quantitative identification of proteins that influence miRNA biogenesis by RNA pull-down–SILAC mass spectrometry (RP–SMS)
- (2018) Nila Roy Choudhury et al. METHODS
- Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay
- (2018) Joanna Koszela et al. BMC BIOLOGY
- Regulation of microRNA biogenesis and its crosstalk with other cellular pathways
- (2018) Thomas Treiber et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells
- (2018) Caihong Yi et al. RNA Biology
- Post-transcriptional control of miRNA biogenesis
- (2018) Gracjan Michlewski et al. RNA
- Therapeutic approaches to target alpha-synuclein pathology
- (2017) Patrik Brundin et al. EXPERIMENTAL NEUROLOGY
- Oleic Acid Induces MiR-7 Processing through Remodeling of Pri-MiR-7/Protein Complex
- (2017) Santosh Kumar et al. JOURNAL OF MOLECULAR BIOLOGY
- Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease
- (2017) Muhammet Ay et al. JOURNAL OF NEUROCHEMISTRY
- Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo
- (2017) Kirsty J. McMillan et al. MOLECULAR THERAPY
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- Discovering the 3′ UTR-mediated regulation of alpha-synuclein
- (2017) Domenica Marchese et al. NUCLEIC ACIDS RESEARCH
- miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions
- (2017) Chih-Hung Chou et al. NUCLEIC ACIDS RESEARCH
- A pathology atlas of the human cancer transcriptome
- (2017) Mathias Uhlen et al. SCIENCE
- A synthetic cell permeable antioxidant protects neurons against acute oxidative stress
- (2017) Nicola J. Drummond et al. Scientific Reports
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Suppression of MicroRNA-7 (miR-7) Biogenesis by Nuclear Factor 90-Nuclear Factor 45 Complex (NF90-NF45) Controls Cell Proliferation in Hepatocellular Carcinoma
- (2016) Takuma Higuchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MiR-133b ameliorates axon degeneration induced by MPP+ via targeting RhoA
- (2016) M. Niu et al. NEUROSCIENCE
- Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates
- (2016) Timothy J. Collier et al. Frontiers in Neuroscience
- Functional Anatomy of the Human Microprocessor
- (2015) Tuan Anh Nguyen et al. CELL
- shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson’s disease model
- (2015) Alevtina D. Zharikov et al. JOURNAL OF CLINICAL INVESTIGATION
- Parkinson's disease
- (2015) Lorraine V Kalia et al. LANCET
- Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations
- (2015) Benjamin Dehay et al. LANCET NEUROLOGY
- The role of quercetin on the survival of neuron-like PC12 cells and the expression of α-synuclein
- (2015) BeomS Jeon et al. Neural Regeneration Research
- 2016 update of the PRIDE database and its related tools
- (2015) Juan Antonio Vizcaíno et al. NUCLEIC ACIDS RESEARCH
- The biological functions of miRNAs: lessons from in vivo studies
- (2015) Joana A. Vidigal et al. TRENDS IN CELL BIOLOGY
- Predicting effective microRNA target sites in mammalian mRNAs
- (2015) Vikram Agarwal et al. eLife
- Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?
- (2014) Amy Reeve et al. AGEING RESEARCH REVIEWS
- Lin28a regulates neuronal differentiation and controls miR-9 production
- (2014) Jakub S. Nowak et al. Nature Communications
- Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite
- (2014) Carina C Clingman et al. eLife
- Oxidized quercetin inhibits α-synuclein fibrillization
- (2013) Min Zhu et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Tissue-specific control of brain-enriched miR-7 biogenesis
- (2013) N. R. Choudhury et al. GENES & DEVELOPMENT
- The QKI-5 and QKI-6 RNA Binding Proteins Regulate the Expression of MicroRNA 7 in Glial Cells
- (2013) Yunling Wang et al. MOLECULAR AND CELLULAR BIOLOGY
- Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson’s disease in rats
- (2013) S.S. Karuppagounder et al. NEUROSCIENCE
- Systematic screens of proteins binding to synthetic microRNA precursors
- (2012) Harry Towbin et al. NUCLEIC ACIDS RESEARCH
- Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR
- (2011) Svetlana Lebedeva et al. MOLECULAR CELL
- Identification of a Small Molecule Inhibitor of Importin β Mediated Nuclear Import by Confocal On-Bead Screening of Tagged One-Bead One-Compound Libraries
- (2010) Martin Hintersteiner et al. ACS Chemical Biology
- Post-transcriptional Regulation of α-Synuclein Expression by mir-7 and mir-153
- (2010) Epaminondas Doxakis JOURNAL OF BIOLOGICAL CHEMISTRY
- A Splicing-Independent Function of SF2/ASF in MicroRNA Processing
- (2010) Han Wu et al. MOLECULAR CELL
- In Vivo RNAi-Mediated α-Synuclein Silencing Induces Nigrostriatal Degeneration
- (2010) Oleg S Gorbatyuk et al. MOLECULAR THERAPY
- The widespread regulation of microRNA biogenesis, function and decay
- (2010) Jacek Krol et al. NATURE REVIEWS GENETICS
- RNase-assisted RNA chromatography
- (2010) G. Michlewski et al. RNA
- Single Bead Labeling Method for Combining Confocal Fluorescence On-Bead Screening and Solution Validation of Tagged One-Bead One-Compound Libraries
- (2009) Martin Hintersteiner et al. CHEMISTRY & BIOLOGY
- Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-α mRNA
- (2009) Min-Ju Chae et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Parkinson's disease: from monogenic forms to genetic susceptibility factors
- (2009) S. Lesage et al. HUMAN MOLECULAR GENETICS
- Confocal Nanoscanning, Bead Picking (CONA): PickoScreen Microscopes for Automated and Quantitative Screening of One-Bead One-Compound Libraries
- (2009) Martin Hintersteiner et al. JOURNAL OF COMBINATORIAL CHEMISTRY
- Repression of -synuclein expression and toxicity by microRNA-7
- (2009) E. Junn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Terminal Adenosyl Transferase Activity of Posttranscriptional Regulator HuR Revealed by Confocal On-Bead Screening
- (2008) Nicole-Claudia Meisner et al. JOURNAL OF MOLECULAR BIOLOGY
- Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA
- (2008) Inha Heo et al. MOLECULAR CELL
- Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops
- (2008) Gracjan Michlewski et al. MOLECULAR CELL
- Circulating microRNAs as stable blood-based markers for cancer detection
- (2008) P. S. Mitchell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
- (2008) M. A. Newman et al. RNA
- Selective Blockade of MicroRNA Processing by Lin28
- (2008) S. R. Viswanathan et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More