标题
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
作者
关键词
-
出版物
NATURE NEUROSCIENCE
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-05-25
DOI
10.1038/s41593-021-00862-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival
- (2020) Alexander Schulz et al. JOURNAL OF CELL BIOLOGY
- Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation
- (2020) Ross A. Weber et al. MOLECULAR CELL
- Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway
- (2020) Xiaoyan Guo et al. NATURE
- Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease
- (2020) Yutaka Oji et al. BRAIN
- Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism
- (2020) Isha H. Jain et al. CELL
- CRISPR-based functional genomics for neurological disease
- (2020) Martin Kampmann Nature Reviews Neurology
- CRISP-view: a database of functional genetic screens spanning multiple phenotypes
- (2020) Yingbo Cui et al. NUCLEIC ACIDS RESEARCH
- The BioGRID database: A comprehensive biomedical resource of curated protein, genetic and chemical interactions
- (2020) Rose Oughtred et al. PROTEIN SCIENCE
- WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs
- (2019) Yuxing Liao et al. NUCLEIC ACIDS RESEARCH
- Mechanistic Target of Rapamycin Complex 1 Signaling Modulates Vascular Endothelial Function Through Reactive Oxygen Species
- (2019) John J. Reho et al. Journal of the American Heart Association
- Paralog dependency indirectly affects the robustness of human cells
- (2019) Rohan Dandage et al. Molecular Systems Biology
- CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons
- (2019) Ruilin Tian et al. NEURON
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
- (2019) Kirill Bersuker et al. NATURE
- Defining essential genes for human pluripotent stem cells by CRISPR–Cas9 screening in haploid cells
- (2018) Atilgan Yilmaz et al. NATURE CELL BIOLOGY
- On the design of CRISPR-based single-cell molecular screens
- (2018) Andrew J Hill et al. NATURE METHODS
- Human pluripotent reprogramming with CRISPR activators
- (2018) Jere Weltner et al. Nature Communications
- Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia
- (2018) Philip W. Brownjohn et al. Stem Cell Reports
- The Spectrin-Actin-Based Periodic Cytoskeleton as a Conserved Nanoscale Scaffold and Ruler of the Neural Stem Cell Lineage
- (2018) Meghan Hauser et al. Cell Reports
- Salmon provides fast and bias-aware quantification of transcript expression
- (2017) Rob Patro et al. NATURE METHODS
- Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
- (2017) Traver Hart et al. G3-Genes Genomes Genetics
- Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch
- (2017) David Ross et al. Frontiers in Physiology
- Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening
- (2017) Chao Wang et al. Stem Cell Reports
- An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells
- (2017) Julia TCW et al. Stem Cell Reports
- Disorders of lysosomal acidification—The emerging role of v-ATPase in aging and neurodegenerative disease
- (2016) Daniel J. Colacurcio et al. AGEING RESEARCH REVIEWS
- Identification of ACSL4 as a biomarker and contributor of ferroptosis
- (2016) Hua Yuan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response
- (2016) Britt Adamson et al. CELL
- Deficiency of Parkinson’s disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation
- (2016) Marta Delgado-Camprubi et al. CELL DEATH AND DIFFERENTIATION
- Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
- (2016) Chenran Wang et al. JOURNAL OF CELL BIOLOGY
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation
- (2016) Chuntao Zhao et al. Nature Communications
- Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
- (2016) Max A Horlbeck et al. eLife
- Graphene-enabled electron microscopy and correlated super-resolution microscopy of wet cells
- (2015) Michal Wojcik et al. Nature Communications
- DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes
- (2015) J. Pinero et al. Database-The Journal of Biological Databases and Curation
- A Guide to Generating and Using hiPSC Derived NPCs for the Study of Neurological Diseases
- (2015) Aaron Topol et al. Jove-Journal of Visualized Experiments
- Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
- (2014) Luke A. Gilbert et al. CELL
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Exome Sequencing Reveals De Novo WDR45 Mutations Causing a Phenotypically Distinct, X-Linked Dominant Form of NBIA
- (2012) Tobias B. Haack et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Keap1 degradation by autophagy for the maintenance of redox homeostasis
- (2012) K. Taguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
- (2012) Yoichi Imaizumi et al. Molecular Brain
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- Identification of Cholesterol-Regulating Genes by Targeted RNAi Screening
- (2009) Fabian Bartz et al. Cell Metabolism
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- Antiapoptotic and Trophic Effects of Dominant-Negative Forms of Dual Leucine Zipper Kinase in Dopamine Neurons of the Substantia Nigra In Vivo
- (2008) X. Chen et al. JOURNAL OF NEUROSCIENCE
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