Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation

Dynamics and Mechanisms of CNS Myelination

(2015) Kathryn K. Bercury et al.   DEVELOPMENTAL CELL

Canonical Wnt signaling in the oligodendroglial lineage-puzzles remain

(2015) Fuzheng Guo et al.   GLIA

Differential Sox10 genomic occupancy in myelinating glia

(2015) Camila Lopez-Anido et al.   GLIA

The Wnt Effector Transcription Factor 7-Like 2 Positively Regulates Oligodendrocyte Differentiation in a Manner Independent of Wnt/ -Catenin Signaling

(2015) E. Hammond et al.   JOURNAL OF NEUROSCIENCE

Type 2 diabetes reduces the proliferation and survival of oligodendrocyte progenitor cells in ishchemic white matter lesions

(2015) Y. Yatomi et al.   NEUROSCIENCE

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF

(2014) Jurian Schuijers et al.   EMBO JOURNAL

Direct visualization of membrane architecture of myelinating cells in transgenic mice expressing membrane-anchored EGFP

(2014) Yaqi Deng et al.   GENESIS

Stage-Specific Regulation of Oligodendrocyte Development by Wnt/ -Catenin Signaling

(2014) Z.-M. Dai et al.   JOURNAL OF NEUROSCIENCE

Mutation of 3-Hydroxy-3-Methylglutaryl CoA Synthase I Reveals Requirements for Isoprenoid and Cholesterol Synthesis in Oligodendrocyte Migration Arrest, Axon Wrapping, and Myelin Gene Expression

(2014) E. S. Mathews et al.   JOURNAL OF NEUROSCIENCE

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity

(2014) Anna V. Molofsky et al.   NATURE

The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells

(2014) Luke Norton et al.   NUCLEIC ACIDS RESEARCH

Motor skill learning requires active central myelination

(2014) I. A. McKenzie et al.   SCIENCE

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

(2014) Maggie C. Y. Ng et al.   PLoS Genetics

Olig2 Targets Chromatin Remodelers to Enhancers to Initiate Oligodendrocyte Differentiation

(2013) Yang Yu et al.   CELL

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

(2013) Xiaoning Han et al.   Cell Stem Cell

Intrinsic and extrinsic control of oligodendrocyte development

(2013) J Bradley Zuchero et al.   CURRENT OPINION IN NEUROBIOLOGY

Adenomatous Polyposis Coli Regulates Oligodendroglial Development

(2013) J. Lang et al.   JOURNAL OF NEUROSCIENCE

Limited TCF7L2 Expression in MS Lesions

(2013) Alexander Lürbke et al.   PLoS One

Coordinated control of oligodendrocyte development by extrinsic and intrinsic signaling cues

(2013) Li He et al.   Neuroscience Bulletin

Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand

(2012) Sylvia F. Boj et al.   CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Pleiotrophin Suppression of Receptor Protein Tyrosine Phosphatase- /  Maintains the Self-Renewal Competence of Fetal Human Oligodendrocyte Progenitor Cells

(2012) C. R. McClain et al.   JOURNAL OF NEUROSCIENCE

A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal

(2012) J. H. van Es et al.   MOLECULAR AND CELLULAR BIOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve

(2012) Rajini Srinivasan et al.   NUCLEIC ACIDS RESEARCH

Tcf7l2 is Tightly Controlled During Myelin Formation

(2011) Hui Fu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo

(2011) Kasum Azim et al.   GLIA

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

(2009) Laura Arce et al.   BMC CANCER

The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways

(2009) A. Ruzov et al.   DEVELOPMENT

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

(2009) Luan Shu et al.   HUMAN MOLECULAR GENETICS

A Genome-Wide Screen for Spatially Restricted Expression Patterns Identifies Transcription Factors That Regulate Glial Development

(2009) H. Fu et al.   JOURNAL OF NEUROSCIENCE

Wnt signaling is sufficient to perturb oligodendrocyte maturation

(2009) Keith Feigenson et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

(2009) Feng Ye et al.   NATURE NEUROSCIENCE

Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells

(2008) P. Hatzis et al.   MOLECULAR AND CELLULAR BIOLOGY