A compendium of uniformly processed human gene expression and splicing quantitative trait loci
出版年份 2021 全文链接
标题
A compendium of uniformly processed human gene expression and splicing quantitative trait loci
作者
关键词
-
出版物
NATURE GENETICS
Volume 53, Issue 9, Pages 1290-1299
出版商
Springer Science and Business Media LLC
发表日期
2021-09-07
DOI
10.1038/s41588-021-00924-w
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation
- (2021) Julie Jerber et al. NATURE GENETICS
- Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genes
- (2021) Jeremy Schwartzentruber et al. NATURE GENETICS
- Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs
- (2021) Qingbo S. Wang et al. Nature Communications
- The nf-core framework for community-curated bioinformatics pipelines
- (2020) Philip A. Ewels et al. NATURE BIOTECHNOLOGY
- The GWAS Diversity Monitor tracks diversity by disease in real time
- (2020) Melinda C. Mills et al. NATURE GENETICS
- Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression
- (2020) Anna S. E. Cuomo et al. Nature Communications
- Quantifying genetic effects on disease mediated by assayed gene expression levels
- (2020) Douglas W. Yao et al. NATURE GENETICS
- PlaToLoCo: the first web meta-server for visualization and annotation of low complexity regions in proteins
- (2020) Patryk Jarnot et al. NUCLEIC ACIDS RESEARCH
- Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses
- (2020) Chris Wallace PLoS Genetics
- Discovery of novel hepatocyte eQTLs in African Americans
- (2020) Yizhen Zhong et al. PLoS Genetics
- A simple new approach to variable selection in regression, with application to genetic fine mapping
- (2020) Gao Wang et al. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
- Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
- (2020) Jie Zheng et al. NATURE GENETICS
- Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
- (2020) Maya Ghoussaini et al. NUCLEIC ACIDS RESEARCH
- Where Are the Disease-Associated eQTLs?
- (2020) Benjamin D. Umans et al. TRENDS IN GENETICS
- Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids
- (2020) Adriaan van der Graaf et al. Nature Communications
- Functionally informed fine-mapping and polygenic localization of complex trait heritability
- (2020) Omer Weissbrod et al. NATURE GENETICS
- Qtlizer: comprehensive QTL annotation of GWAS results
- (2020) Matthias Munz et al. Scientific Reports
- Genetic effects on promoter usage are highly context-specific and contribute to complex traits
- (2019) Kaur Alasoo et al. eLife
- On Using Local Ancestry to Characterize the Genetic Architecture of Human Traits: Genetic Regulation of Gene Expression in Multiethnic or Admixed Populations
- (2019) Yizhen Zhong et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle
- (2019) D. Leland Taylor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations
- (2019) Mihir A Kamat et al. BIOINFORMATICS
- Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
- (2019) Eleonora Porcu et al. Nature Communications
- Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
- (2019) Daehwan Kim et al. NATURE BIOTECHNOLOGY
- Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations
- (2019) Roseann E. Peterson et al. CELL
- Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
- (2019) Charles P. Fulco et al. NATURE GENETICS
- QTLbase: an integrative resource for quantitative trait loci across multiple human molecular phenotypes
- (2019) Zhanye Zheng et al. NUCLEIC ACIDS RESEARCH
- Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes
- (2019) Ruby J Roach et al. NUCLEIC ACIDS RESEARCH
- Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs
- (2018) Monique G. P. van der Wijst et al. NATURE GENETICS
- Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response
- (2018) Kaur Alasoo et al. NATURE GENETICS
- Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
- (2018) Andrew E. Jaffe et al. NATURE NEUROSCIENCE
- IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
- (2018) Yukihide Momozawa et al. Nature Communications
- ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci
- (2018) David Stacey et al. NUCLEIC ACIDS RESEARCH
- Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
- (2018) Angli Xue et al. Nature Communications
- Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression
- (2018) Benjamin J. Schmiedel et al. CELL
- Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions
- (2018) Sarah M. Urbut et al. NATURE GENETICS
- ArrayExpress update – from bulk to single-cell expression data
- (2018) Awais Athar et al. NUCLEIC ACIDS RESEARCH
- Common genetic variation drives molecular heterogeneity in human iPSCs
- (2017) Helena Kilpinen et al. NATURE
- Nextflow enables reproducible computational workflows
- (2017) Paolo Di Tommaso et al. NATURE BIOTECHNOLOGY
- Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
- (2017) Katrina M de Lange et al. NATURE GENETICS
- Molecular and functional variation in iPSC-derived sensory neurons
- (2017) Jeremy Schwartzentruber et al. NATURE GENETICS
- Salmon provides fast and bias-aware quantification of transcript expression
- (2017) Rob Patro et al. NATURE METHODS
- An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
- (2017) Bernard Ng et al. NATURE NEUROSCIENCE
- Functional mapping and annotation of genetic associations with FUMA
- (2017) Kyoko Watanabe et al. Nature Communications
- A complete tool set for molecular QTL discovery and analysis
- (2017) Olivier Delaneau et al. Nature Communications
- Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
- (2017) Sarah Kim-Hellmuth et al. Nature Communications
- C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis
- (2017) Kaido Lepik et al. PLoS Computational Biology
- Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells
- (2017) Silva Kasela et al. PLoS Genetics
- FINEMAP: efficient variable selection using summary data from genome-wide association studies
- (2016) Christian Benner et al. BIOINFORMATICS
- Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells
- (2016) Lu Chen et al. CELL
- The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
- (2016) William J. Astle et al. CELL
- Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens
- (2016) Yohann Nédélec et al. CELL
- Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations
- (2016) Hélène Quach et al. CELL
- Reference-based phasing using the Haplotype Reference Consortium panel
- (2016) Po-Ru Loh et al. NATURE GENETICS
- Next-generation genotype imputation service and methods
- (2016) Sayantan Das et al. NATURE GENETICS
- Consensus Genome-Wide Expression Quantitative Trait Loci and Their Relationship with Human Complex Trait Disease
- (2016) Chen-Hsin Yu et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- RNA splicing is a primary link between genetic variation and disease
- (2016) Yang I. Li et al. SCIENCE
- The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability
- (2016) Alexander D. Diehl et al. Journal of Biomedical Semantics
- Fast and efficient QTL mapper for thousands of molecular phenotypes
- (2015) Halit Ongen et al. BIOINFORMATICS
- SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations
- (2015) Xiaowei Zhan et al. GENETIC EPIDEMIOLOGY
- An integrated map of structural variation in 2,504 human genomes
- (2015) Peter H. Sudmant et al. NATURE
- A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
- (2015) Majid Nikpay et al. NATURE GENETICS
- Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
- (2015) James Bentham et al. NATURE GENETICS
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- The human transcriptome across tissues and individuals
- (2015) M. Mele et al. SCIENCE
- Genomic modulators of gene expression in human neutrophils
- (2015) Vivek Naranbhai et al. Nature Communications
- Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors
- (2015) Martijn van de Bunt et al. PLoS Genetics
- Second-generation PLINK: rising to the challenge of larger and richer datasets
- (2015) Christopher C Chang et al. GigaScience
- Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins
- (2014) Alfonso Buil et al. NATURE GENETICS
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- CrossMap: a versatile tool for coordinate conversion between genome assemblies
- (2013) Hao Zhao et al. BIOINFORMATICS
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Transcriptome and genome sequencing uncovers functional variation in humans
- (2013) Tuuli Lappalainen et al. NATURE
- Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories
- (2013) Peter A C 't Hoen et al. NATURE BIOTECHNOLOGY
- A Statistical Framework for Joint eQTL Analysis in Multiple Tissues
- (2013) Timothée Flutre et al. PLoS Genetics
- Passive and active DNA methylation and the interplay with genetic variation in gene regulation
- (2013) Maria Gutierrez-Arcelus et al. eLife
- Improved Heritability Estimation from Genome-wide SNPs
- (2012) Doug Speed et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Removing technical variability in RNA-seq data using conditional quantile normalization
- (2012) K. D. Hansen et al. BIOSTATISTICS
- Detecting differential usage of exons from RNA-seq data
- (2012) S. Anders et al. GENOME RESEARCH
- GENCODE: The reference human genome annotation for The ENCODE Project
- (2012) J. Harrow et al. GENOME RESEARCH
- Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
- (2012) Benjamin P Fairfax et al. NATURE GENETICS
- Measurement of mRNA abundance using RNA-seq data: RPKM measure is inconsistent among samples
- (2012) Günter P. Wagner et al. THEORY IN BIOSCIENCES
- Uberon, an integrative multi-species anatomy ontology
- (2012) Christopher J Mungall et al. GENOME BIOLOGY
- MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects
- (2011) Harm-Jan Westra et al. BIOINFORMATICS
- seeQTL: a searchable database for human eQTLs
- (2011) Kai Xia et al. BIOINFORMATICS
- Tabix: fast retrieval of sequence features from generic TAB-delimited files
- (2011) H. Li BIOINFORMATICS
- Modeling sample variables with an Experimental Factor Ontology
- (2010) James Malone et al. BIOINFORMATICS
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Common SNPs in HMGCR in Micronesians and Whites Associated With LDL-Cholesterol Levels Affect Alternative Splicing of Exon13
- (2008) Ralph Burkhardt et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- lumi: a pipeline for processing Illumina microarray
- (2008) P. Du et al. BIOINFORMATICS
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