标题
Allosteric transcription stimulation by RNA polymerase II super elongation complex
作者
关键词
transcription, RNA polymerase II, super elongation complex, ELL2, EAF1, P-TEFb, stimulation of transcription elongation, TFIIF, RNA Pol II lobe and protrusion
出版物
MOLECULAR CELL
Volume 81, Issue 16, Pages 3386-3399.e10
出版商
Elsevier BV
发表日期
2021-07-14
DOI
10.1016/j.molcel.2021.06.019
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression
- (2021) Bin Zheng et al. GENES & DEVELOPMENT
- Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription
- (2020) Dan Tang et al. Cell Discovery
- Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation
- (2020) Seychelle M. Vos et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization
- (2019) Ying Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural basis of TFIIH activation for nucleotide excision repair
- (2019) Goran Kokic et al. Nature Communications
- A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides
- (2019) Zhen-Lin Chen et al. Nature Communications
- Namdinator – automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps
- (2019) Rune Thomas Kidmose et al. IUCrJ
- Real-time cryo-electron microscopy data preprocessing with Warp
- (2019) Dimitry Tegunov et al. NATURE METHODS
- DALI and the persistence of protein shape
- (2019) Liisa Holm PROTEIN SCIENCE
- A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core
- (2018) Lukas Zimmermann et al. JOURNAL OF MOLECULAR BIOLOGY
- Born to run: control of transcription elongation by RNA polymerase II
- (2018) Fei Xavier Chen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Real-space refinement in PHENIX for cryo-EM and crystallography
- (2018) Pavel V. Afonine et al. Acta Crystallographica Section D-Structural Biology
- Structure of paused transcription complex Pol II–DSIF–NELF
- (2018) Seychelle M. Vos et al. NATURE
- Structure of activated transcription complex Pol II–DSIF–PAF–SPT6
- (2018) Seychelle M. Vos et al. NATURE
- RNA polymerase II clustering through carboxy-terminal domain phase separation
- (2018) Marc Boehning et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The PRIDE database and related tools and resources in 2019: improving support for quantification data
- (2018) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- New tools for automated high-resolution cryo-EM structure determination in RELION-3
- (2018) Jasenko Zivanov et al. eLife
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- Structure of a transcribing RNA polymerase II–DSIF complex reveals a multidentate DNA–RNA clamp
- (2017) Carrie Bernecky et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription
- (2017) Shiqian Qi et al. Nature Communications
- Structure of a transcribing RNA polymerase II–DSIF complex reveals a multidentate DNA–RNA clamp
- (2017) Carrie Bernecky et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of transcribing mammalian RNA polymerase II
- (2016) Carrie Bernecky et al. NATURE
- Near-atomic resolution visualization of human transcription promoter opening
- (2016) Yuan He et al. NATURE
- Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb
- (2016) Alexandre J. C. Quaresma et al. NUCLEIC ACIDS RESEARCH
- Architecture and RNA binding of the human negative elongation factor
- (2016) Seychelle M Vos et al. eLife
- Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex
- (2016) Ursula Schulze-Gahmen et al. eLife
- Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide
- (2015) Fei Chen et al. GENES & DEVELOPMENT
- xiNET: Cross-link Network Maps With Residue Resolution
- (2015) Colin W. Combe et al. MOLECULAR & CELLULAR PROTEOMICS
- The Phyre2 web portal for protein modeling, prediction and analysis
- (2015) Lawrence A Kelley et al. Nature Protocols
- RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II
- (2015) M. Yu et al. SCIENCE
- AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation
- (2014) Yuanyuan Li et al. CELL
- Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4
- (2014) Jianyou Gu et al. CELL CYCLE
- Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation
- (2014) Friederike Itzen et al. NUCLEIC ACIDS RESEARCH
- A series of PDB-related databanks for everyday needs
- (2014) Wouter G. Touw et al. NUCLEIC ACIDS RESEARCH
- Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms
- (2014) V. Schweikhard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter
- (2014) Ursula Schulze-Gahmen et al. eLife
- Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons
- (2014) Iris Jonkers et al. eLife
- Stable Pausing by RNA Polymerase II Provides an Opportunity to Target and Integrate Regulatory Signals
- (2013) Telmo Henriques et al. MOLECULAR CELL
- Structural insights into Paf1 complex assembly and histone binding
- (2013) Xinlei Chu et al. NUCLEIC ACIDS RESEARCH
- AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation
- (2013) H. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat
- (2013) Ursula Schulze-Gahmen et al. eLife
- The Super Elongation Complex Family of RNA Polymerase II Elongation Factors: Gene Target Specificity and Transcriptional Output
- (2012) Z. Luo et al. MOLECULAR AND CELLULAR BIOLOGY
- Structure and function of the initially transcribing RNA polymerase II–TFIIB complex
- (2012) Sarah Sainsbury et al. NATURE
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
- (2012) Karen Adelman et al. NATURE REVIEWS GENETICS
- The super elongation complex (SEC) family in transcriptional control
- (2012) Zhuojuan Luo et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold
- (2012) S. Chou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Leukemia Fusion Target AF9 Is an Intrinsically Disordered Transcriptional Regulator that Recruits Multiple Partners via Coupled Folding and Binding
- (2012) Benjamin I. Leach et al. STRUCTURE
- Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC)
- (2011) C. Lin et al. GENES & DEVELOPMENT
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- A Higher-Order Complex Containing AF4 and ENL Family Proteins with P-TEFb Facilitates Oncogenic and Physiologic MLL-Dependent Transcription
- (2010) Akihiko Yokoyama et al. CANCER CELL
- RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex
- (2010) Sebastian R. Geiger et al. MOLECULAR CELL
- HIV-1 Tat and Host AFF4 Recruit Two Transcription Elongation Factors into a Bifunctional Complex for Coordinated Activation of HIV-1 Transcription
- (2010) Nanhai He et al. MOLECULAR CELL
- AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia
- (2010) Chengqi Lin et al. MOLECULAR CELL
- HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP
- (2010) Bijan Sobhian et al. MOLECULAR CELL
- Jalview Version 2--a multiple sequence alignment editor and analysis workbench
- (2009) A. M. Waterhouse et al. BIOINFORMATICS
- Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused RNA Polymerase II with Frayed RNA
- (2009) Jasmin F. Sydow et al. MOLECULAR CELL
- Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila
- (2009) S. Nechaev et al. SCIENCE
- Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters
- (2008) Leighton J. Core et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation