Small interfering RNA (siRNA) to target genes and molecular pathways in glioblastoma therapy: Current status with an emphasis on delivery systems
出版年份 2021 全文链接
标题
Small interfering RNA (siRNA) to target genes and molecular pathways in glioblastoma therapy: Current status with an emphasis on delivery systems
作者
关键词
Small interfering RNA (siRNA), Glioblastoma multiforme, Brain tumor, Gene therapy, Nanoparticles, Delivery vehicles
出版物
LIFE SCIENCES
Volume 275, Issue -, Pages 119368
出版商
Elsevier BV
发表日期
2021-03-18
DOI
10.1016/j.lfs.2021.119368
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Biomedical application of chitosan-based nanoscale delivery systems: Potential usefulness in siRNA delivery for cancer therapy
- (2021) Milad Ashrafizadeh et al. CARBOHYDRATE POLYMERS
- Inhibition of PLK4 might enhance the anti‐tumour effect of bortezomib on glioblastoma via PTEN/PI3K/AKT/mTOR signalling pathway
- (2020) Jing Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The role of extracellular vesicles and PD-L1 in glioblastoma-mediated immunosuppressive monocyte induction
- (2020) Benjamin T Himes et al. NEURO-ONCOLOGY
- Functionalized Folate-Modified Graphene Oxide/PEI siRNA Nanocomplexes for Targeted Ovarian Cancer Gene Therapy
- (2020) Yunfei Wang et al. Nanoscale Research Letters
- Histone 2A Family Member J Drives Mesenchymal Transition and Temozolomide Resistance in Glioblastoma Multiforme
- (2020) Hsun-Hua Lee et al. Cancers
- Resistance Mechanisms and Barriers to Successful Immunotherapy for Treating Glioblastoma
- (2020) Jason Adhikaree et al. Cells
- Single siRNA Nanocapsules for Effective siRNA Brain Delivery and Glioblastoma Treatment
- (2020) Yan Zou et al. ADVANCED MATERIALS
- Elevation of CXCL1 indicates poor prognosis and radioresistance by inducing mesenchymal transition in glioblastoma
- (2020) Wahafu Alafate et al. CNS Neuroscience & Therapeutics
- Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma
- (2020) Wen-Bin Yang et al. NEURO-ONCOLOGY
- Generation and validation of structurally defined antibody–siRNA conjugates
- (2020) Alex R Nanna et al. NUCLEIC ACIDS RESEARCH
- E2F transcription factor 8 promotes proliferation and radioresistance in glioblastoma
- (2020) Hai Yu et al. PATHOLOGY RESEARCH AND PRACTICE
- Melanoma Cancer Immunotherapy Using PD-L1 siRNA and Imatinib Promotes Cancer-Immunity Cycle
- (2020) Chenyang Li et al. PHARMACEUTICAL RESEARCH
- RSF-1 siRNA Enhances Tumor Radiosensitivity in Cervical Cancer via Enhanced DNA Damage, Cell Cycle Redistribution, and Promotion of Apoptosis
- (2020) Jing Tian et al. OncoTargets and Therapy
- Ultrasound-Mediated Long-Circulating Nanopolymer Delivery of Therapeutic siRNA and Antisense MicroRNAs Leads to Enhanced Paclitaxel Sensitivity in Epithelial Ovarian Cancer Chemotherapy
- (2020) Yi Liu et al. ACS Biomaterials-Science & Engineering
- Glioblastoma: Pathogenesis and Current Status of Chemotherapy and Other Novel Treatments
- (2020) Vilashini Rajaratnam et al. Cancers
- STAT3 Inhibitor ODZ10117 Suppresses Glioblastoma Malignancy and Prolongs Survival in a Glioblastoma Xenograft Model
- (2020) Byung-Hak Kim et al. Cells
- Endocytosis: The Nanoparticle and Submicron Nanocompounds Gateway into the Cell
- (2020) Darío Manzanares et al. Pharmaceutics
- Temozolomide–Doxorubicin Conjugate as a Double Intercalating Agent and Delivery by Apoferritin for Glioblastoma Chemotherapy
- (2020) Ke Du et al. ACS Applied Materials & Interfaces
- Management of glioblastoma: State of the art and future directions
- (2020) Aaron C. Tan et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Skin Delivery of siRNA Using Sponge Spicules in Combination with Cationic Flexible Liposomes
- (2020) XueJiao Liang et al. Molecular Therapy-Nucleic Acids
- Glioblastoma Therapy Using Codelivery of Cisplatin and Glutathione Peroxidase Targeting siRNA from Iron Oxide Nanoparticles
- (2020) Yulin Zhang et al. ACS Applied Materials & Interfaces
- Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC
- (2020) Hao Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mirror siRNAs loading for dual delivery of doxorubicin and autophagy regulation siRNA for multidrug reversing chemotherapy
- (2020) Bo Yang et al. BIOMEDICINE & PHARMACOTHERAPY
- Exosomes-coated bcl-2 siRNA inhibits the growth of digestive system tumors both in vitro and in vivo
- (2020) Hongyu Tao et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- A Novel Therapeutic siRNA Nanoparticle Designed for Dual-Targeting CD44 and Gli1 of Gastric Cancer Stem Cells
- (2020) Hongjuan Yao et al. International Journal of Nanomedicine
- RNA Synthesis by DNA Methyltransferase 1 siRNA Transfection with Cationic Liposomes into Osteoblastic Progenitor Cells Based on SiO2 Nanomagnetic Beads for Proliferation and Differentiation
- (2020) Qingzhen Chen et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation
- (2020) Fatemeh Madani et al. LIFE SCIENCES
- Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma
- (2020) Zammam Areeb et al. Scientific Reports
- The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance
- (2020) Filippo Torrisi et al. Cancers
- Radioresistance in Glioblastoma and the Development of Radiosensitizers
- (2020) Md Yousuf Ali et al. Cancers
- Hemagglutinating virus of Japan‐envelope containing programmed cell death‐ligand 1 siRNA inhibits immunosuppressive activities and elicits antitumor immune responses in glioma
- (2020) Narushi Sugii et al. CANCER SCIENCE
- miR-624-3p Promotes Esophageal Squamous Cell Carcinoma Progression via Targeting Phosphatase and Tensin Homologue
- (2020) Hongyu Jia et al. DNA AND CELL BIOLOGY
- Cyclodextrin-Based Nanostructure Efficiently Delivers siRNA to Glioblastoma Cells Preferentially via Macropinocytosis
- (2020) Darío Manzanares et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Silencing of MEF2D by siRNA Loaded Selenium Nanoparticles for Ovarian Cancer Therapy
- (2020) Changbing Wang et al. International Journal of Nanomedicine
- Treatment of Colon Cancer by Degradable rrPPC Nano-Conjugates Delivered STAT3 siRNA
- (2020) Hongjia Zhang et al. International Journal of Nanomedicine
- Multifaceted targeting of cationic liposomes via co-delivery of anti-IL-17 siRNA and corticosteroid for topical treatment of psoriasis
- (2020) Krishna Yadav et al. MEDICAL HYPOTHESES
- PD-L1-Mediated Immunosuppression in Glioblastoma Is Associated With the Infiltration and M2-Polarization of Tumor-Associated Macrophages
- (2020) Zhiyuan Zhu et al. Frontiers in Immunology
- Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-responsive complex in triple negative breast cancer cells
- (2020) Chi Zhang et al. LIFE SCIENCES
- Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model
- (2019) Benedikt Linder et al. Cancers
- Immunotherapy for glioblastoma: quo vadis?
- (2019) Michael Weller et al. Nature Reviews Clinical Oncology
- Brain Tumor Microenvironment and Host State: Implications for Immunotherapy
- (2019) William Tomaszewski et al. CLINICAL CANCER RESEARCH
- Resveratrol and siRNA in combination reduces Hsp27 expression and induces caspase-3 activity in human glioblastoma cells
- (2019) Evren Önay Uçar et al. CELL STRESS & CHAPERONES
- RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells
- (2019) Bo Lou et al. Drug Delivery and Translational Research
- Engineered targeting tLyp-1 exosomes as gene therapy vectors for efficient delivery of siRNA into lung cancer cells
- (2019) Jing Bai et al. Asian Journal of Pharmaceutical Sciences
- A Fit-for-Purpose Method for the Detection of Human Antibodies to Surface-Exposed Components of BMS-986263, a Lipid Nanoparticle-Based Drug Product Containing a siRNA Drug Substance
- (2019) Uma Kavita et al. AAPS Journal
- ROS‐Responsive Polymeric siRNA Nanomedicine Stabilized by Triple Interactions for the Robust Glioblastoma Combinational RNAi Therapy
- (2019) Meng Zheng et al. ADVANCED MATERIALS
- Delineation of crosstalk between HSP27 and MMP-2/MMP-9: A synergistic therapeutic avenue for glioblastoma management
- (2019) Y. Rajesh et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Long noncoding RNA MALAT1 may be a prognostic biomarker in IDH1/2 wild-type primary glioblastomas
- (2019) Omer Gokay Argadal et al. Bosnian Journal of Basic Medical Sciences
- Multifunctional Cationic PeptoStars as siRNA Carrier: Influence of Architecture and Histidine Modification on Knockdown Potential
- (2019) Regina Holm et al. MACROMOLECULAR BIOSCIENCE
- Nasal Administration of Cationic Nanoemulsions as CD73-siRNA Delivery System for Glioblastoma Treatment: a New Therapeutical Approach
- (2019) J. H. Azambuja et al. MOLECULAR NEUROBIOLOGY
- Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms
- (2019) Vagisha Ravi et al. PLoS One
- Circulating biomarkers in patients with glioblastoma
- (2019) Juliana Müller Bark et al. BRITISH JOURNAL OF CANCER
- Dysregulation of glutamate transport enhances Treg function that promotes VEGF blockade resistance in glioblastoma
- (2019) Yu Long et al. CANCER RESEARCH
- Cholesterol grafted cationic lipopolymers: Potential siRNA carriers for selective chronic myeloid leukemia therapy
- (2019) KC Remant et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Combination of attenuated Salmonella carrying PD‐1 siRNA with nifuroxazide for colon cancer therapy
- (2019) Tiesuo Zhao et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Co-delivery of GOLPH3 siRNA and gefitinib by cationic lipid-PLGA nanoparticles improves EGFR-targeted therapy for glioma
- (2019) Chengkun Ye et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- cMyc and ERK activity are associated with resistance to ALK inhibitory treatment in glioblastoma
- (2019) Anne Berberich et al. JOURNAL OF NEURO-ONCOLOGY
- Enhanced anticancer effect of doxorubicin by TPGS-coated liposomes with Bcl-2 siRNA-corona for dual suppression of drug resistance
- (2019) Yinghuan Li et al. Asian Journal of Pharmaceutical Sciences
- A selective Aurora-A 5′-UTR siRNA inhibits tumor growth and metastasis
- (2019) Chien-Hsien Lai et al. CANCER LETTERS
- Extracellular vesicle (ECV)-modified polyethylenimine (PEI) complexes for enhanced siRNA delivery in vitro and in vivo
- (2019) Petro Zhupanyn et al. JOURNAL OF CONTROLLED RELEASE
- Development and characterization of CD73-siRNA-loaded nanoemulsion: effect on C6 glioma cells and primary astrocytes
- (2019) Fernanda C. Teixeira et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- A review of traditional Chinese medicine for treatment of glioblastoma
- (2019) Jinjing Wang et al. BioScience Trends
- Micelle-like nanoparticles as siRNA and miRNA carriers for cancer therapy
- (2018) Daniel F. Costa et al. BIOMEDICAL MICRODEVICES
- Rosmarinic acid and siRNA combined therapy represses Hsp27 (HSPB1) expression and induces apoptosis in human glioma cells
- (2018) Aslıhan Şengelen et al. CELL STRESS & CHAPERONES
- Effect of an siRNA Therapeutic Targeting PCSK9 on Atherogenic Lipoproteins: Pre-Specified Secondary End Points in ORION 1
- (2018) Kausik K. Ray et al. CIRCULATION
- Cyclodextrin-siRNA conjugates as versatile gene silencing agents
- (2018) Meenakshi Malhotra et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Selective induction of cancer cell death by VDAC1-based peptides and their potential use in cancer therapy
- (2018) Anna Shteinfer-Kuzmine et al. Molecular Oncology
- Current state of immunotherapy for glioblastoma
- (2018) Michael Lim et al. Nature Reviews Clinical Oncology
- Alnylam prepares to land first RNAi drug approval
- (2018) Chris Morrison NATURE REVIEWS DRUG DISCOVERY
- Oxymatrine induces cell cycle arrest and apoptosis and suppresses the invasion of human glioblastoma cells through the EGFR/PI3K/Akt/mTOR signaling pathway and STAT3
- (2018) Zhibo Dai et al. ONCOLOGY REPORTS
- Therapeutic nanosystems co-deliver anticancer drugs and oncogene SiRNA to achieve synergetic precise cancer chemo-gene therapy
- (2018) Wei Huang et al. Journal of Materials Chemistry B
- Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma
- (2018) Wing Yin Tong et al. JOURNAL OF NANOBIOTECHNOLOGY
- STAT3 Gene Silencing by Aptamer-siRNA Chimera as Selective Therapeutic for Glioblastoma
- (2018) Carla Lucia Esposito et al. Molecular Therapy-Nucleic Acids
- Adult Glioma Incidence and Survival by Race or Ethnicity in the United States From 2000 to 2014
- (2018) Quinn T. Ostrom et al. JAMA Oncology
- PEI-Coated Fe3O4 Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells
- (2018) Rui Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Systemic siRNA delivery to tumors by cell-penetrating α-helical polypeptide-based metastable nanoparticles
- (2018) Yang Liu et al. Nanoscale
- CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011–2015
- (2018) Quinn T Ostrom et al. NEURO-ONCOLOGY
- Harnessing the immune system in glioblastoma
- (2018) Nicholas F. Brown et al. BRITISH JOURNAL OF CANCER
- miR-186 reverses cisplatin resistance and inhibits the�formation of the glioblastoma-initiating cell�phenotype by degrading Yin Yang 1 in glioblastoma
- (2018) Jian Li et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Porous silicon nanoparticle as a stabilizing support for chondroitinase
- (2017) Sara Daneshjou et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Cationic nanoemulsions as nucleic acids delivery systems
- (2017) Helder Ferreira Teixeira et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Delivering siRNA and Chemotherapeutic Molecules Across BBB and BTB for Intracranial Glioblastoma Therapy
- (2017) Zhen-zhen Yang et al. MOLECULAR PHARMACEUTICS
- Clinical Proof of Concept for a Novel Hepatocyte-Targeting GalNAc-siRNA Conjugate
- (2017) Tracy S. Zimmermann et al. MOLECULAR THERAPY
- VDAC1 is a molecular target in glioblastoma, with its depletion leading to reprogrammed metabolism and reversed oncogenic properties
- (2017) Tasleem Arif et al. NEURO-ONCOLOGY
- Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide
- (2017) Sang-Soo Kim et al. NUCLEIC ACIDS RESEARCH
- Quetiapine Nanoemulsion for Intranasal Drug Delivery: Evaluation of Brain-Targeting Efficiency
- (2016) Mithila Boche et al. AAPS PHARMSCITECH
- Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy
- (2016) Tingting Lin et al. ACS Nano
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Reducing VDAC1 expression induces a non-apoptotic role for pro-apoptotic proteins in cancer cell differentiation
- (2016) Tasleem Arif et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Combination Therapy with AKT3 and PI3KCA siRNA Enhances the Antitumor Effect of Temozolomide and Carmustine in T98G Glioblastoma Multiforme Cells
- (2016) Monika Paul-Samojedny et al. BIODRUGS
- CXCR4-targeted modular peptide carriers for efficient anti-VEGF siRNA delivery
- (2016) Anna Egorova et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Development of siRNA-loaded chitosan nanoparticles targeting Galectin-1 for the treatment of glioblastoma multiforme via intranasal administration
- (2016) Matthias Van Woensel et al. JOURNAL OF CONTROLLED RELEASE
- Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo
- (2016) Junyang Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Silencing of epidermal growth factor, latrophilin and seven transmembrane domain-containing protein 1 (ELTD1) via siRNA-induced cell death in glioblastoma
- (2016) Florentina Serban et al. JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY
- Quercetin blocks t-AUCB-induced autophagy by Hsp27 and Atg7 inhibition in glioblastoma cells in vitro
- (2016) Junyang Li et al. JOURNAL OF NEURO-ONCOLOGY
- RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy
- (2016) Seung-Hwan Park et al. Theranostics
- Dual-drug delivery by porous silicon nanoparticles for improved cellular uptake, sustained release, and combination therapy
- (2015) Chang-Fang Wang et al. Acta Biomaterialia
- Glioblastoma: pathology, molecular mechanisms and markers
- (2015) Kenneth Aldape et al. ACTA NEUROPATHOLOGICA
- Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: In vitro analysis
- (2015) Matt Gooding et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: In vivo evaluation
- (2015) Fabienne Danhier et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Pharmacokinetic strategies to improve drug penetration and entrapment within solid tumors
- (2015) Ahmed M. Al-Abd et al. JOURNAL OF CONTROLLED RELEASE
- Cationic Nanoemulsions as a Gene Delivery System: Proof of Concept in the Mucopolysaccharidosis I Murine Model
- (2015) Michelle Fraga et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Oligonucleotide delivery by chitosan-functionalized porous silicon nanoparticles
- (2015) Morteza Hasanzadeh Kafshgari et al. Nano Research
- Effect of siRNA-Livin on drug resistance to chemotherapy in glioma U251 cells and CD133+ stem cells
- (2015) YANG LIU et al. Experimental and Therapeutic Medicine
- Current Therapeutic Advances Targeting EGFR and EGFRvIII in Glioblastoma
- (2015) Emily Padfield et al. Frontiers in Oncology
- Bioreducible Cationic Polymer-Based Nanoparticles for Efficient and Environmentally Triggered Cytoplasmic siRNA Delivery to Primary Human Brain Cancer Cells
- (2014) Kristen L. Kozielski et al. ACS Nano
- Dual-Targeting Upconversion Nanoprobes across the Blood–Brain Barrier for Magnetic Resonance/Fluorescence Imaging of Intracranial Glioblastoma
- (2014) Dalong Ni et al. ACS Nano
- Drug Delivery: Cancer-Targeted Monodisperse Mesoporous Silica Nanoparticles as Carrier of Ruthenium Polypyridyl Complexes to Enhance Theranostic Effects (Adv. Funct. Mater. 19/2014)
- (2014) Lizhen He et al. ADVANCED FUNCTIONAL MATERIALS
- High-grade glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
- (2014) R. Stupp et al. ANNALS OF ONCOLOGY
- Dual Receptor-Specific Peptides Modified Liposomes as VEGF siRNA Vector for Tumor-Targeting Therapy
- (2014) Zhenzhen Yang et al. CURRENT GENE THERAPY
- Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide
- (2014) Frederic Lagarce et al. International Journal of Nanomedicine
- In vitro and in vivo intracellular distribution and anti-glioblastoma effects of docetaxel-loaded nanoparticles functioned with IL-13 peptide
- (2014) Huile Gao et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: Current progress and advances
- (2014) Nishant S. Gandhi et al. JOURNAL OF CONTROLLED RELEASE
- Quantitative measurement of delivery and gene silencing activities of siRNA polyplexes containing pyridylthiourea-grafted polyethylenimines
- (2014) Sophie Pinel et al. JOURNAL OF CONTROLLED RELEASE
- Multifunctional Cationic Lipid-Based Nanoparticles Facilitate Endosomal Escape and Reduction-Triggered Cytosolic siRNA Release
- (2014) Maneesh Gujrati et al. MOLECULAR PHARMACEUTICS
- Synergistic Dual-Ligand Doxorubicin Liposomes Improve Targeting and Therapeutic Efficacy of Brain Glioma in Animals
- (2014) Taili Zong et al. MOLECULAR PHARMACEUTICS
- Cancer-targeting siRNA delivery from porous silicon nanoparticles
- (2014) Yuan Wan et al. Nanomedicine
- Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications
- (2014) Hélder A Santos et al. Nanomedicine
- CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011
- (2014) Q. T. Ostrom et al. NEURO-ONCOLOGY
- Glioblastoma cancer stem cells: Biomarker and therapeutic advances
- (2014) Kelli B. Pointer et al. NEUROCHEMISTRY INTERNATIONAL
- Targeting of EGFR and HER2 with therapeutic antibodies and siRNA
- (2014) Henri Wichmann et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Construction and evaluation of controlled-release delivery system of Abamectin using porous silica nanoparticles as carriers
- (2014) Yan Wang et al. Nanoscale Research Letters
- Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo
- (2014) Tasleem Arif et al. Molecular Therapy-Nucleic Acids
- Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway
- (2013) Howard A. Burris CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90
- (2013) Mirela Matokanovic et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Interplay of stimuli-responsiveness, drug loading and release for a surface-engineered dendrimer delivery system
- (2013) Ruihong Liu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles
- (2013) Dongfei Liu et al. JOURNAL OF CONTROLLED RELEASE
- Poly(trehalose): Sugar-Coated Nanocomplexes Promote Stabilization and Effective Polyplex-Mediated siRNA Delivery
- (2013) Antons Sizovs et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- siRNA-mediated knockdown of SMC1A expression suppresses the proliferation of glioblastoma cells
- (2013) Ying Yang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Reversal of multidrug resistance by magnetic chitosan-Fe3O4 nanoparticle-encapsulated MDR1 siRNA in glioblastoma cell line
- (2013) Peng Zhao et al. NEUROLOGICAL RESEARCH
- Expansive growth of two glioblastoma stem-like cell lines is mediated by bFGF and not by EGF
- (2013) Neza Podergajs et al. Radiology and Oncology
- Targeting the PI3K/AKT/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding
- (2013) Arshawn Sami et al. TUMOR BIOLOGY
- First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement
- (2013) Josep Tabernero et al. Cancer Discovery
- Click-Modified Cyclodextrins as Nonviral Vectors for Neuronal siRNA Delivery
- (2012) A. M. O’Mahony et al. ACS Chemical Neuroscience
- Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery
- (2012) Swati Biswas et al. BIOMATERIALS
- The Definition of Primary and Secondary Glioblastoma
- (2012) H. Ohgaki et al. CLINICAL CANCER RESEARCH
- Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for siRNA and DNA Delivery to Human Brain Cancer
- (2012) Stephany Y. Tzeng et al. Advanced Healthcare Materials
- Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing
- (2011) Mahesh L. Patil et al. ACS Nano
- Nanotechnological advances for the delivery of CNS therapeutics
- (2011) Ho Lun Wong et al. ADVANCED DRUG DELIVERY REVIEWS
- In Vivo Specific Delivery of c-Met siRNA to Glioblastoma Using Cationic Solid Lipid Nanoparticles
- (2011) Juyoun Jin et al. BIOCONJUGATE CHEMISTRY
- Diblock Glycopolymers Promote Colloidal Stability of Polyplexes and Effective pDNA and siRNA Delivery under Physiological Salt and Serum Conditions
- (2011) Adam E. Smith et al. BIOMACROMOLECULES
- Plexin-A4 promotes tumor progression and tumor angiogenesis by enhancement of VEGF and bFGF signaling
- (2011) B. Kigel et al. BLOOD
- Influence of phospholipid composition on cationic emulsions/DNA complexes: physicochemical properties, cytotoxicity, and transfection on Hep G2 cells
- (2011) Helder Teixeira et al. International Journal of Nanomedicine
- PEGylated thermo-sensitive poly(amidoamine) dendritic drug delivery systems
- (2011) Yanjun Zhao et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251
- (2011) Jun Liu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Research progress on Livin protein: an inhibitor of apoptosis
- (2011) Biao Yan MOLECULAR AND CELLULAR BIOCHEMISTRY
- siRNA targeting Notch-1 decreases glioma stem cell proliferation and tumor growth
- (2011) Jianpeng Wang et al. MOLECULAR BIOLOGY REPORTS
- Synergistic Induction of Apoptosis in Brain Cancer Cells by Targeted Codelivery of siRNA and Anticancer Drugs
- (2011) Cheoljin Kim et al. MOLECULAR PHARMACEUTICS
- Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM
- (2011) Y.-W. Kim et al. NEURO-ONCOLOGY
- Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery
- (2010) Omid Veiseh et al. BIOMATERIALS
- Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells
- (2010) T Kato et al. GENE THERAPY
- Adenovirus-mediated transfer of siRNA against basic fibroblast growth factor mRNA enhances the sensitivity of glioblastoma cells to chemotherapy
- (2010) Xuequan Feng et al. MEDICAL ONCOLOGY
- VDAC, a multi-functional mitochondrial protein regulating cell life and death
- (2010) Varda Shoshan-Barmatz et al. MOLECULAR ASPECTS OF MEDICINE
- Aptamers as therapeutics
- (2010) Anthony D. Keefe et al. NATURE REVIEWS DRUG DISCOVERY
- Functional Delivery of siRNA in Mice Using Dendriworms
- (2009) Amit Agrawal et al. ACS Nano
- Small-Molecule End-Groups of Linear Polymer Determine Cell-type Gene-Delivery Efficacy
- (2009) Joel Sunshine et al. ADVANCED MATERIALS
- Mechanisms of Endocytosis
- (2009) Gary J. Doherty et al. Annual Review of Biochemistry
- Origins and Mechanisms of miRNAs and siRNAs
- (2009) Richard W. Carthew et al. CELL
- Highly efficient eradication of intracranial glioblastoma using Eg5 siRNA combined with HVJ envelope
- (2009) M Matsuda et al. GENE THERAPY
- Nanostructured mesoporous silica matrices in nanomedicine
- (2009) M. Vallet-Regà JOURNAL OF INTERNAL MEDICINE
- Combination gene therapy with PTEN and EGFR siRNA suppresses U251 malignant glioma cell growth in vitro and in vivo
- (2009) Lei Han et al. MEDICAL ONCOLOGY
- A three-dimensional view of the molecular machinery of RNA interference
- (2009) Martin Jinek et al. NATURE
- Non-viral nanosystems for systemic siRNA delivery
- (2009) Stephanie David et al. PHARMACOLOGICAL RESEARCH
- Combination of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma cells and inhibits invasion, angiogenesis and tumour growth
- (2008) Joseph George et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Bcl-2 siRNA Augments Taxol Mediated Apoptotic Death in Human Glioblastoma U138MG and U251MG Cells
- (2008) Joseph George et al. NEUROCHEMICAL RESEARCH
- Mesoporous Silicon in Drug Delivery Applications
- (2007) Jarno Salonen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now