6-shogaol attenuates H2O2-induced oxidative stress via upregulation of Nrf2-mediated γ-glutamylcysteine synthetase and heme oxygenase expression in HepG2 cells

Influence of side chain structure changes on antioxidant potency of the [6]-gingerol related compounds

(2014) Dong-Liang Lu et al.   FOOD CHEMISTRY

Characterization of thiol-conjugated metabolites of ginger components shogaols in mouse and human urine and modulation of the glutathione levels in cancer cells by [6]-shogaol

(2013) Huadong Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways

(2013) Fei-Fei Gan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes

(2013) Ji Hye Yang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

(2012) Holly K. Bryan et al.   BIOCHEMICAL PHARMACOLOGY

Cytotoxic, cytoprotective and antioxidant effects of isolated phenolic compounds from fresh ginger

(2012) Fang Peng et al.   FITOTERAPIA

In vitro antioxidant and anti-inflammatory activities of 1-dehydro-[6]-gingerdione, 6-shogaol, 6-dehydroshogaol and hexahydrocurcumin

(2012) Feng Li et al.   FOOD CHEMISTRY

6-Shogaol-Rich Extract from Ginger Up-Regulates the Antioxidant Defense Systems in Cells and Mice

(2012) Min-Ji Bak et al.   MOLECULES

The cytoprotective role of the Keap1–Nrf2 pathway

(2011) Liam Baird et al.   ARCHIVES OF TOXICOLOGY

Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: Involvement of p38

(2011) Ana Belén Granado-Serrano et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anti-inflammatory effects of [6]-shogaol: Potential roles of HDAC inhibition and HSP70 induction

(2011) Sehwan Shim et al.   FOOD AND CHEMICAL TOXICOLOGY

Tumor necrosis factor-α treatment of HepG2 cells mobilizes a cytoplasmic pool of ERp57/1,25D3-MARRS to the nucleus

(2011) Brian J. Grindel et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Induction of the Keap1/Nrf2/ARE pathway by oxidizable diphenols

(2010) Albena T. Dinkova-Kostova et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Quantitative Analysis of Ginger Components in Commercial Products Using Liquid Chromatography with Electrochemical Array Detection

(2010) Xi Shao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol

(2009) Swarnalatha Dugasani et al.   JOURNAL OF ETHNOPHARMACOLOGY

6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages

(2008) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH