标题
Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target
作者
关键词
-
出版物
Journal of Hematology & Oncology
Volume 14, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-09-16
DOI
10.1186/s13045-021-01161-8
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles
- (2021) Chunai Gong et al. JOURNAL OF NANOBIOTECHNOLOGY
- Eicosapentaenoic Acid Inhibits KRAS Mutant Pancreatic Cancer Cell Growth by Suppressing Hepassocin Expression and STAT3 Phosphorylation
- (2021) Ching-Feng Chiu et al. Biomolecules
- Fibrinogen-Like Protein 1 Modulates Sorafenib Resistance in Human Hepatocellular Carcinoma Cells
- (2021) Yeonghoon Son et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The intersection of COVID-19 and cancer: signaling pathways and treatment implications
- (2021) Zhi Zong et al. Molecular Cancer
- Clinical Insights Into Novel Immune Checkpoint Inhibitors
- (2021) Jii Bum Lee et al. Frontiers in Pharmacology
- Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit
- (2020) Christopher S. Morrow et al. Cell Stem Cell
- F-Actin Interactome Reveals Vimentin as a Key Regulator of Actin Organization and Cell Mechanics in Mitosis
- (2020) Murielle P. Serres et al. DEVELOPMENTAL CELL
- To be or not to be: whether anti-angiogenic agent combined with immune checkpoint inhibitoris necessary in the treatment of advanced or metastatic renal cell carcinoma
- (2020) Leitao Sun et al. MEDICAL ONCOLOGY
- TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1
- (2020) Jie Su et al. NATURE
- Clinical diagnosis and treatment of immune checkpoint inhibitor‐associated adverse events in the digestive system
- (2020) Yue Li et al. Thoracic Cancer
- NK Cell-Based Immune Checkpoint Inhibition
- (2020) Muhammad Khan et al. Frontiers in Immunology
- Current Understanding of the Mechanisms Underlying Immune Evasion From PD-1/PD-L1 Immune Checkpoint Blockade in Head and Neck Cancer
- (2020) Victor C. Kok Frontiers in Oncology
- ICOS Is an Indicator of T-cell–Mediated Response to Cancer Immunotherapy
- (2020) Zunyu Xiao et al. CANCER RESEARCH
- Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases
- (2020) Naganari Ohkura et al. CELL RESEARCH
- Cancer Cell–Intrinsic Expression of MHC Class II Regulates the Immune Microenvironment and Response to Anti–PD-1 Therapy in Lung Adenocarcinoma
- (2020) Amber M. Johnson et al. JOURNAL OF IMMUNOLOGY
- The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapy
- (2020) Xueping Wang et al. Molecular Cancer
- Precision Medicine for NSCLC in the Era of Immunotherapy: New Biomarkers to Select the Most Suitable Treatment or the Most Suitable Patient
- (2020) Giovanni Rossi et al. Cancers
- Mechanism and potential predictive biomarkers of immune checkpoint inhibitors in NSCLC
- (2020) Jialin Qu et al. BIOMEDICINE & PHARMACOTHERAPY
- Expression and clinical significance of LAG-3, FGL1, PD-L1 and CD8+T cells in hepatocellular carcinoma using multiplex quantitative analysis
- (2020) Mengzhou Guo et al. Journal of Translational Medicine
- On the use of immune checkpoint inhibitors in patients with viral infections including COVID-19
- (2020) Thilo Gambichler et al. Journal for ImmunoTherapy of Cancer
- Correlation Between Tumor-Associated Macrophage and Immune Checkpoint Molecule Expression and Its Prognostic Significance in Cutaneous Melanoma
- (2020) Young Jae Kim et al. Journal of Clinical Medicine
- Targeting STAT3 in Cancer Immunotherapy
- (2020) Sailan Zou et al. Molecular Cancer
- Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer
- (2020) Grégoire de Streel et al. Nature Communications
- Oxysophocarpine suppresses hepatocellular carcinoma growth and sensitizes the therapeutic blockade of anti‐Lag‐3 via reducing FGL1 expression
- (2020) Jianchu Wang et al. Cancer Medicine
- Matrix Metalloproteinase-12 Is Required for Granuloma Progression
- (2020) Arjun Mohan et al. Frontiers in Immunology
- Fibrinogen-Like Protein 1 Is a Novel Biomarker for Predicting Disease Activity and Prognosis of Rheumatoid Arthritis
- (2020) Shijia Liu et al. Frontiers in Immunology
- LAG-3: from molecular functions to clinical applications
- (2020) Takumi Maruhashi et al. Journal for ImmunoTherapy of Cancer
- TIGIT in cancer immunotherapy
- (2020) Joe-Marc Chauvin et al. Journal for ImmunoTherapy of Cancer
- Resistance to PD-1/PD-L1 blockade cancer immunotherapy: mechanisms, predictive factors, and future perspectives
- (2020) Jin-Yu Sun et al. Biomarker Research
- The critical role of CD4+ T cells in PD-1 blockade against MHC-II–expressing tumors such as classic Hodgkin lymphoma
- (2020) Joji Nagasaki et al. Blood Advances
- The Value of Liquid Biopsies for Guiding Therapy Decisions in Non-small Cell Lung Cancer
- (2019) Jatta Saarenheimo et al. Frontiers in Oncology
- Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer
- (2019) Sunil Singhal et al. Science Translational Medicine
- Dynamic Changes in the Niche with N-Cadherin Revisited: The HSC “Niche Herein”
- (2019) Ayako Nakamura-Ishizu et al. Cell Stem Cell
- MEST induces Twist-1-mediated EMT through STAT3 activation in breast cancers
- (2019) Min Soo Kim et al. CELL DEATH AND DIFFERENTIATION
- Expression analysis and significance of PD-1, LAG-3 and TIM-3 in human non-small cell lung cancer using spatially-resolved and multiparametric single-cell analysis.
- (2019) Ila J Datar et al. CLINICAL CANCER RESEARCH
- Pleiotropy and Specificity: Insights from the Interleukin 6 Family of Cytokines
- (2019) Masaaki Murakami et al. IMMUNITY
- Transforming Growth Factor-β Signaling in Immunity and Cancer
- (2019) Eduard Batlle et al. IMMUNITY
- Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance
- (2019) Filipe Martins et al. Nature Reviews Clinical Oncology
- The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis
- (2019) Michelle A. Mintz et al. IMMUNITY
- Immune checkpoint inhibitors: The linchpins of modern immunotherapy
- (2019) Breelyn A. Wilky IMMUNOLOGICAL REVIEWS
- Understanding and overcoming the resistance of cancer to PD-1/PD-L1 blockade
- (2019) Amy L. Shergold et al. PHARMACOLOGICAL RESEARCH
- Twists and turns to translating 4-1BB cancer immunotherapy
- (2019) Miguel F. Sanmamed et al. Science Translational Medicine
- RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
- (2019) Xinyao Lin et al. Nature Communications
- hnRNPK S379 phosphorylation participates in migration regulation of triple negative MDA-MB-231 cells
- (2019) Hsin-Yu Tsai et al. Scientific Reports
- Mechanisms of immune-related adverse events associated with immune checkpoint blockade: using germline genetics to develop a personalized approach
- (2019) Zia Khan et al. Genome Medicine
- Circulating Tumor Cell PD-L1 Expression as Biomarker for Therapeutic Efficacy of Immune Checkpoint Inhibition in NSCLC
- (2019) Kloten et al. Cells
- Preclinical Development of the Anti-LAG-3 Antibody REGN3767: Characterization and Activity in Combination with the Anti-PD-1 Antibody Cemiplimab in Human PD-1xLAG-3 Knock-In Mice
- (2019) Elena Burova et al. MOLECULAR CANCER THERAPEUTICS
- PD-1 and LAG-3 Dominate Checkpoint Receptor–Mediated T-cell Inhibition in Renal Cell Carcinoma
- (2019) Henning Zelba et al. Cancer Immunology Research
- Different Expression Characteristics of LAG3 and PD-1 in Sepsis and Their Synergistic Effect on T Cell Exhaustion: A New Strategy for Immune Checkpoint Blockade
- (2019) Bailin Niu et al. Frontiers in Immunology
- Plasma Fibrinogen-Like 1 as a Potential Biomarker for Radiation-Induced Liver Injury
- (2019) Na-Kyung Han et al. Cells
- Mechanosensation of Tight Junctions Depends on ZO-1 Phase Separation and Flow
- (2019) Cornelia Schwayer et al. CELL
- mRNA and lncRNA Expression Profiling of Radiation-Induced Gastric Injury Reveals Potential Radiation-Responsive Transcription Factors
- (2019) Guangxia Chen et al. Dose-Response
- Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4
- (2019) Shuang Qin et al. Molecular Cancer
- Repurposing of drugs as STAT3 inhibitors for cancer therapy
- (2019) Pathum S. Thilakasiri et al. SEMINARS IN CANCER BIOLOGY
- A gene regulatory network to control EMT programs in development and disease
- (2019) Hassan Fazilaty et al. Nature Communications
- PD-L1+ aneuploid circulating tumor endothelial cells (CTECs) exhibit resistance to the checkpoint blockade immunotherapy in advanced NSCLC patients
- (2019) Lina Zhang et al. CANCER LETTERS
- The superior efficacy of anti-PD-1/PD-L1 immunotherapy in KRAS-mutant non-small cell lung cancer that correlates with an inflammatory phenotype and increased immunogenicity
- (2019) Chengming Liu et al. CANCER LETTERS
- Targeting fibrinogen‐like protein 1 is a novel therapeutic strategy to combat obesity
- (2019) Hung‐Tsung Wu et al. FASEB JOURNAL
- The co-expression characteristics of LAG3 and PD-1 on the T cells of patients with breast cancer reveal a new therapeutic strategy
- (2019) Huimin Du et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Harnessing tumor-associated macrophages as aids for cancer immunotherapy
- (2019) Xiaolei Li et al. Molecular Cancer
- Quantitative Comparative Proteomics Reveal Biomarkers for Dengue Disease Severity
- (2019) Lifen Han et al. Frontiers in Microbiology
- Blocking CD47 efficiently potentiated therapeutic effects of anti-angiogenic therapy in non-small cell lung cancer
- (2019) Xuyao Zhang et al. Journal for ImmunoTherapy of Cancer
- Fibronectin in Cancer: Friend or Foe
- (2019) Tsung-Cheng Lin et al. Cells
- Mechanisms of resistance to immune checkpoint inhibitors
- (2018) Russell W Jenkins et al. BRITISH JOURNAL OF CANCER
- Mechanisms of Resistance to PD-1 and PD-L1 Blockade
- (2018) Theodore S. Nowicki et al. CANCER JOURNAL
- Circulating tumor cells undergoing EMT provide a metric for diagnosis and prognosis of patients with hepatocellular carcinoma
- (2018) Lu-Nan Qi et al. CANCER RESEARCH
- ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism
- (2018) Mingyang Liu et al. CLINICAL CANCER RESEARCH
- Combination Cancer Therapy with Immune Checkpoint Blockade: Mechanisms and Strategies
- (2018) Shetal A. Patel et al. IMMUNITY
- Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
- (2018) Fei Zhao et al. IMMUNITY
- LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells
- (2018) Andreia C. Lino et al. IMMUNITY
- Lymphocyte-Activation Gene-3 Expression and Prognostic Value in Neoadjuvant-Treated Triple-Negative Breast Cancer
- (2018) Yunxuan Wang et al. Journal of Breast Cancer
- Next generation of immune checkpoint therapy in cancer: new developments and challenges
- (2018) Julian A. Marin-Acevedo et al. Journal of Hematology & Oncology
- Hyperlipidemia-induced hepassocin in the liver contributes to insulin resistance in skeletal muscle
- (2018) Tae Woo Jung et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Myeloid-derived suppressor cells coming of age
- (2018) Filippo Veglia et al. NATURE IMMUNOLOGY
- Immune-Related Adverse Events Associated with Immune Checkpoint Blockade
- (2018) Michael A. Postow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetic, transcriptional and post-translational regulation of the programmed death protein ligand 1 in cancer: biology and clinical correlations
- (2018) Ioannis Zerdes et al. ONCOGENE
- MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma
- (2018) Scott J. Rodig et al. Science Translational Medicine
- Genetic Mechanisms of Immune Evasion in Colorectal Cancer
- (2018) Catherine S. Grasso et al. Cancer Discovery
- CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-L1 blockade
- (2018) Limo Chen et al. Cancer Discovery
- CRISPR/Cas9 -mediated gene knockout of Anopheles gambiae FREP1 suppresses malaria parasite infection
- (2018) Yuemei Dong et al. PLoS Pathogens
- Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells
- (2018) Felix S. Lichtenegger et al. Frontiers in Immunology
- PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer
- (2018) Magalie Dosset et al. OncoImmunology
- Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations
- (2018) Jun Gong et al. Journal for ImmunoTherapy of Cancer
- Evolutionary Pressure against MHC Class II Binding Cancer Mutations
- (2018) Rachel Marty et al. CELL
- sLAG-3 in non-small-cell lung cancer patients’ serum
- (2018) Yayi He et al. OncoTargets and Therapy
- Overcoming Acquired PD-1/PD-L1 Resistance with CD38 Blockade
- (2018) Deepak Mittal et al. Cancer Discovery
- Anti-PD-1/PD-L1 Therapy for Non-Small-Cell Lung Cancer: Toward Personalized Medicine and Combination Strategies
- (2018) Hongshu Sui et al. Journal of Immunology Research
- A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
- (2018) Livnat Jerby-Arnon et al. CELL
- Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3
- (2018) Jun Wang et al. CELL
- Identification of molecular signatures involved in radiation-induced lung fibrosis
- (2018) Hee Jin et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Biochemical Aspects of PD-L1 Regulation in Cancer Immunotherapy
- (2018) Jinfang Zhang et al. TRENDS IN BIOCHEMICAL SCIENCES
- Tim-3 and its role in regulating anti-tumor immunity
- (2017) Madhumita Das et al. IMMUNOLOGICAL REVIEWS
- Immunoregulatory functions of VISTA
- (2017) Elizabeth C. Nowak et al. IMMUNOLOGICAL REVIEWS
- LAG3 (CD223) as a cancer immunotherapy target
- (2017) Lawrence P. Andrews et al. IMMUNOLOGICAL REVIEWS
- Primary and acquired resistance to PD-1/PD-L1 blockade in cancer treatment
- (2017) Qiaohong Wang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The Hepatic Protection Effects of Hepassocin in Hyperglycemic Crisis
- (2017) Horng-Yih Ou et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The Potential of Combined Immunotherapy and Antiangiogenesis for the Synergistic Treatment of Advanced NSCLC
- (2017) Christian Manegold et al. Journal of Thoracic Oncology
- LAG-3 Protein Expression in Non–Small Cell Lung Cancer and Its Relationship with PD-1/PD-L1 and Tumor-Infiltrating Lymphocytes
- (2017) Yayi He et al. Journal of Thoracic Oncology
- The need for a network to establish and validate predictive biomarkers in cancer immunotherapy
- (2017) Giuseppe V. Masucci et al. Journal of Translational Medicine
- PD-L1 expression in advanced NSCLC: Insights into risk stratification and treatment selection from a systematic literature review
- (2017) Robert Brody et al. LUNG CANCER
- IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: overview and new insights
- (2017) Heming Li et al. Molecular Cancer
- Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation
- (2017) Su Yeon Lee et al. Molecular Cancer
- Effective combinatorial immunotherapy for castration-resistant prostate cancer
- (2017) Xin Lu et al. NATURE
- T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition
- (2017) Enfu Hui et al. SCIENCE
- Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation
- (2017) Elizabeth Allen et al. Science Translational Medicine
- ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC
- (2017) Darina Lazarova et al. Journal of Cancer
- Myeloid-Derived Suppressor Cells
- (2017) Dmitry I. Gabrilovich Cancer Immunology Research
- Characteristics and outcomes of patients with advanced sarcoma enrolled in early phase immunotherapy trials
- (2017) Roman Groisberg et al. Journal for ImmunoTherapy of Cancer
- Antiangiogenesis for Advanced Non-Small-Cell Lung Cancer in the Era of Immunotherapy and Personalized Medicine
- (2017) Samer Tabchi et al. Frontiers in Oncology
- Strategies and Approaches of Targeting STAT3 for Cancer Treatment
- (2016) Steffanie L. Furtek et al. ACS Chemical Biology
- Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
- (2016) Jianjun Gao et al. CELL
- Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs)
- (2016) C. Alfaro et al. CLINICAL CANCER RESEARCH
- Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy
- (2016) S. J. Blake et al. CLINICAL CANCER RESEARCH
- Differential Expression and Significance of PD-L1, IDO-1, and B7-H4 in Human Lung Cancer
- (2016) Kurt A. Schalper et al. CLINICAL CANCER RESEARCH
- Hyperprogressive Disease Is a New Pattern of Progression in Cancer Patients Treated by Anti-PD-1/PD-L1
- (2016) Stéphane Champiat et al. CLINICAL CANCER RESEARCH
- A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes
- (2016) Hung-Tsung Wu et al. DIABETOLOGIA
- Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
- (2016) Jonathan M. Pitt et al. IMMUNITY
- ZEB1 drives epithelial-to-mesenchymal transition in lung cancer
- (2016) Jill E. Larsen et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-6 pathway in the liver: From physiopathology to therapy
- (2016) Dirk Schmidt-Arras et al. JOURNAL OF HEPATOLOGY
- Targeting Epithelial–Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer
- (2016) Bowen Du et al. MOLECULES
- Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination
- (2016) Celine Boutros et al. Nature Reviews Clinical Oncology
- Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
- (2016) Vassiliki A. Boussiotis NEW ENGLAND JOURNAL OF MEDICINE
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations
- (2016) Weiping Zou et al. Science Translational Medicine
- Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations
- (2016) Daniel Sanghoon Shin et al. Cancer Discovery
- ICOS Co-Stimulation: Friend or Foe?
- (2016) Daniel J. Wikenheiser et al. Frontiers in Immunology
- Targeted disruption of fibrinogen like protein-1 accelerates hepatocellular carcinoma development
- (2015) Hamed Nayeb-Hashemi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hepassocin is required for hepatic outgrowth during zebrafish hepatogenesis
- (2015) Ming Gao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
- (2015) Stefani Spranger et al. NATURE
- N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN
- (2015) Y Su et al. ONCOGENE
- T cell exclusion, immune privilege, and the tumor microenvironment
- (2015) J. A. Joyce et al. SCIENCE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway
- (2015) Kim C. Ohaegbulam et al. TRENDS IN MOLECULAR MEDICINE
- Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction
- (2015) Sherin J. Rouhani et al. Nature Communications
- Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy
- (2015) A. Holtzhausen et al. Cancer Immunology Research
- Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia
- (2014) Rakesh K. Jain CANCER CELL
- The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection
- (2014) Matthew M. Staron et al. IMMUNITY
- Treg functional stability and its responsiveness to the microenvironment
- (2014) Joseph Barbi et al. IMMUNOLOGICAL REVIEWS
- Nivolumab (Anti-PD-1; BMS-936558, ONO-4538) Maintenance as Monotherapy or in Combination With Bevacizumab (BEV) for Non-Small Cell Lung Cancer (NSCLC) Previously Treated With Chemotherapy
- (2014) N.A. Rizvi et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Human Lymphocyte Activation Gene-3 Molecules Expressed by Activated T Cells Deliver Costimulation Signal for Dendritic Cell Activation
- (2014) C. Casati et al. JOURNAL OF IMMUNOLOGY
- Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
- (2014) Roy S. Herbst et al. NATURE
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells
- (2014) K. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer
- (2013) J. Duraiswamy et al. CANCER RESEARCH
- Targeted Deletion of Fibrinogen Like Protein 1 Reveals a Novel Role in Energy Substrate Utilization
- (2013) Valeriy Demchev et al. PLoS One
- T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
- (2012) Naganari Ohkura et al. IMMUNITY
- The specialized roles of immature and mature dendritic cells in antigen cross-presentation
- (2012) Richard A. Hopkins et al. IMMUNOLOGIC RESEARCH
- Immature Dendritic Cell-Derived Exosomes: a Promise Subcellular Vaccine for Autoimmunity
- (2012) Weifan Yin et al. INFLAMMATION
- Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells
- (2012) Nicole Grabinski et al. Molecular Cancer
- Galectin-3 – A jack-of-all-trades in cancer
- (2011) Anna U. Newlaczyl et al. CANCER LETTERS
- Anti-TIM3 Antibody Promotes T Cell IFN- -Mediated Antitumor Immunity and Suppresses Established Tumors
- (2011) S. F. Ngiow et al. CANCER RESEARCH
- Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape
- (2011) S.-R. Woo et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
- (2011) Taku Okazaki et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MHC Class II Engagement by Its Ligand LAG-3 (CD223) Contributes to Melanoma Resistance to Apoptosis
- (2011) P. Hemon et al. JOURNAL OF IMMUNOLOGY
- IFN- Directly Promotes Programmed Cell Death-1 Transcription and Limits the Duration of T Cell-Mediated Immunity
- (2011) S. Terawaki et al. JOURNAL OF IMMUNOLOGY
- Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
- (2011) Charlly Kao et al. NATURE IMMUNOLOGY
- Hepassocin as a treatment for fulminant hepatic failure: will it translate from rats to human?
- (2010) V. Calvaruso GUT
- Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
- (2009) John M.L. Ebos et al. CANCER CELL
- TGF-β-induced epithelial to mesenchymal transition
- (2009) Jian Xu et al. CELL RESEARCH
- Specific Expression and Regulation of Hepassocin in the Liver and Down-regulation of the Correlation of HNF1α with Decreased Levels of Hepassocin in Human Hepatocellular Carcinoma
- (2009) Hai-Tao Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells
- (2009) J. F. Grosso et al. JOURNAL OF IMMUNOLOGY
- Clearance of hepatitis C in chimpanzees is associated with intrahepatic T-cell perforin expression during the late acute phase
- (2009) H. Watanabe et al. JOURNAL OF VIRAL HEPATITIS
- Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
- (2008) T. T. Onder et al. CANCER RESEARCH
- The cell-cell adhesion molecule E-cadherin
- (2008) F. van Roy et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma
- (2008) Augusto Villanueva et al. GASTROENTEROLOGY
- Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
- (2008) Shawn D Blackburn et al. NATURE IMMUNOLOGY
- Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)
- (2008) M. Marzec et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant
- (2007) Zhilin Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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