CRISPR/Cas9 -mediated gene knockout of Anopheles gambiae FREP1 suppresses malaria parasite infection

The fibrinogen-like domain of FREP1 protein is a broad-spectrum malaria transmission-blocking vaccine antigen

(2017) Guodong Niu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in the microbiota cause genetically modifiedAnophelesto spread in a population

(2017) Andrew Pike et al.   SCIENCE

Striking diflubenzuron resistance in Culex pipiens, the prime vector of West Nile Virus

(2017) Linda Grigoraki et al.   Scientific Reports

The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito

(2017) Andrew M. Hammond et al.   PLoS Genetics

Microbiota-induced peritrophic matrix regulates midgut homeostasis and prevents systemic infection of malaria vector mosquitoes

(2017) Faye H. Rodgers et al.   PLoS Pathogens

Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics

(2016) Philip A. Eckhoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Testing the causality between CYP9M10 and pyrethroid resistance using the TALEN and CRISPR/Cas9 technologies

(2016) Kentaro Itokawa et al.   Scientific Reports

AnophelesMidgut FREP1 MediatesPlasmodiumInvasion

(2015) Genwei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

(2015) Andrew Hammond et al.   NATURE BIOTECHNOLOGY

Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis inAedes aegypti

(2015) Sanjay Basu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquitoAnopheles stephensi

(2015) Valentino M. Gantz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A male-determining factor in the mosquito Aedes aegypti

(2015) A. B. Hall et al.   SCIENCE

Targeting mosquito FREP1 with a fungal metabolite blocks malaria transmission

(2015) Guodong Niu et al.   Scientific Reports

Genome Engineering with CRISPR-Cas9 in the Mosquito Aedes aegypti

(2015) Kathryn E. Kistler et al.   Cell Reports

Tools for Anopheles gambiae Transgenesis

(2015) G. Volohonsky et al.   G3-Genes Genomes Genetics

Heritable CRISPR/Cas9-Mediated Genome Editing in the Yellow Fever Mosquito, Aedes aegypti

(2015) Shengzhang Dong et al.   PLoS One

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases

(2014) Richard L Frock et al.   NATURE BIOTECHNOLOGY

CRISPR/Cas9 Mediates Efficient Conditional Mutagenesis in Drosophila

(2014) Zhaoyu Xue et al.   G3-Genes Genomes Genetics

A compendium of molecules involved in vector-pathogen interactions pertaining to malaria

(2013) Sreelakshmi K Sreenivasamurthy et al.   MALARIA JOURNAL

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

(2013) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Next-Generation Site-Directed Transgenesis in the Malaria Vector Mosquito Anopheles gambiae: Self-Docking Strains Expressing Germline-Specific phiC31 Integrase

(2013) Janet M. Meredith et al.   PLoS One

Genetic approaches to interfere with malaria transmission by vector mosquitoes

(2013) Sibao Wang et al.   TRENDS IN BIOTECHNOLOGY

Transmission-blocking interventions eliminate malaria from laboratory populations

(2013) A. M. Blagborough et al.   Nature Communications

Anopheles NF-κB-Regulated Splicing Factors Direct Pathogen-Specific Repertoires of the Hypervariable Pattern Recognition Receptor AgDscam

(2012) Yuemei Dong et al.   Cell Host & Microbe

Global malaria mortality between 1980 and 2010: a systematic analysis

(2012) Christopher JL Murray et al.   LANCET

Anticoagulation factor I, a snaclec (snake C-type lectin) from Agkistrodon acutus venom binds to FIX as well as FX: Ca2+ induced binding data

(2012) Yan Zhang et al.   TOXICON

Natural Microbe-Mediated Refractoriness to Plasmodium Infection in Anopheles gambiae

(2011) C. M. Cirimotich et al.   SCIENCE

Engineered Anopheles Immunity to Plasmodium Infection

(2011) Yuemei Dong et al.   PLoS Pathogens

A Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae

(2010) S. Kumar et al.   SCIENCE

Activation of Akt Signaling Reduces the Prevalence and Intensity of Malaria Parasite Infection and Lifespan in Anopheles stephensi Mosquitoes

(2010) Vanessa Corby-Harris et al.   PLoS Pathogens

The vasa regulatory region mediates germline expression and maternal transmission of proteins in the malaria mosquito Anopheles gambiae: a versatile tool for genetic control strategies

(2009) Philippos A Papathanos et al.   BMC MOLECULAR BIOLOGY

AnophelesFibrinogen-related Proteins Provide Expanded Pattern Recognition Capacity against Bacteria and Malaria Parasites

(2009) Yuemei Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fine Pathogen Discrimination within the APL1 Gene Family Protects Anopheles gambiae against Human and Rodent Malaria Species

(2009) Christian Mitri et al.   PLoS Pathogens

Fibrinogen-bearing protein genes in the snail Biomphalaria glabrata: Characterization of two novel genes and expression studies during ontogenesis and trematode infection

(2008) Si-Ming Zhang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Expression profiling and binding properties of fibrinogen-related proteins (FREPs), plasma proteins from the schistosome snail host Biomphalaria glabrata

(2008) Si-Ming Zhang et al.   Innate Immunity

Conserved Mosquito/Parasite Interactions Affect Development of Plasmodium falciparum in Africa

(2008) Antonio M. Mendes et al.   PLoS Pathogens