Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles

Targeting therapy for prostate cancer by pharmaceutical and clinical pharmaceutical strategies

(2021) Wanxiao Sun et al.   JOURNAL OF CONTROLLED RELEASE

In situ poly I:C released from living cell drug nanocarriers for macrophage-mediated antitumor immunotherapy

(2021) Haimei Zhou et al.   BIOMATERIALS

Cell-Membrane-Based Biomimetic Systems with Bioorthogonal Functionalities

(2020) Li-Li Huang et al.   ACCOUNTS OF CHEMICAL RESEARCH

A review of cancer immunotherapy toxicity

(2020) Lucy Boyce Kennedy et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Human Anti-tumor Immunity: Insights from Immunotherapy Clinical Trials

(2020) Jackson G. Egen et al.   IMMUNITY

Top 10 Challenges in Cancer Immunotherapy

(2020) Priti S. Hegde et al.   IMMUNITY

M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

(2020) Xueliang Zuo et al.   Journal of Hematology & Oncology

Metformin-Induced Stromal Depletion to Enhance the Penetration of Gemcitabine-Loaded Magnetic Nanoparticles for Pancreatic Cancer Targeted Therapy

(2020) Haijie Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal

(2020) Elana Ben-Akiva et al.   Science Advances

Immune checkpoint inhibitors: Key trials and an emerging role in breast cancer

(2020) Nicola Gaynor et al.   SEMINARS IN CANCER BIOLOGY

Irradiation pretreatment enhances the therapeutic efficacy of platelet-membrane-camouflaged antitumor nanoparticles

(2020) Yin Chen et al.   JOURNAL OF NANOBIOTECHNOLOGY

Macrophage-cancer hybrid membrane-coated nanoparticles for targeting lung metastasis in breast cancer therapy

(2020) Chunai Gong et al.   JOURNAL OF NANOBIOTECHNOLOGY

Treatment after progression in the era of immunotherapy

(2020) Salem Billan et al.   LANCET ONCOLOGY

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Enhanced anti-proliferative and pro-apoptotic effects of metformin encapsulated PLGA-PEG nanoparticles on SKOV3 human ovarian carcinoma cells

(2019) Leila Faramarzi et al.   Artificial Cells Nanomedicine and Biotechnology

Precise targeting of POLR2A as a therapeutic strategy for human triple negative breast cancer

(2019) Jiangsheng Xu et al.   Nature Nanotechnology

Immunotherapy and targeted therapy combinations in metastatic breast cancer

(2019) Francisco J Esteva et al.   LANCET ONCOLOGY

Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours

(2019) Han Yao et al.   Nature Biomedical Engineering

Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages and head and neck squamous cell carcinoma cells

(2019) Xiteng Yin et al.   CELLULAR ONCOLOGY

Encapsulation of Plasmid DNA by Nanoscale Metal–Organic Frameworks for Efficient Gene Transportation and Expression

(2019) Yantao Li et al.   ADVANCED MATERIALS

Selective Cell Penetrating Peptide-Functionalized Envelope-Type Chimeric Lipopepsomes Boost Systemic RNAi Therapy for Lung Tumors

(2019) Min Qiu et al.   Advanced Healthcare Materials

Dual-Blockade Immune Checkpoint for Breast Cancer Treatment Based on a Tumor-Penetrating Peptide Assembling Nanoparticle

(2019) Guorui Li et al.   ACS Applied Materials & Interfaces

Integration of immunogenic activation and immunosuppressive reversion using mitochondrial-respiration-inhibited platelet-mimicking nanoparticles

(2019) Xiaoli Mai et al.   BIOMATERIALS

Defeating relapsed and refractory malignancies through a nano-enabled mitochondria-mediated respiratory inhibition and damage pathway

(2019) Zhengyang Yang et al.   BIOMATERIALS

The co-expression characteristics of LAG3 and PD-1 on the T cells of patients with breast cancer reveal a new therapeutic strategy

(2019) Huimin Du et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Metformin inhibits cell proliferation in SKM-1 cells via AMPK-mediated cell cycle arrest

(2019) Xiaojia Zhou et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

PD-L1 status in breast cancer: Current view and perspectives

(2019) Semir Vranic et al.   SEMINARS IN CANCER BIOLOGY

Overcoming malignant cell-based mechanisms of resistance to immune checkpoint blockade antibodies

(2019) Reham Ajina et al.   SEMINARS IN CANCER BIOLOGY

Molecular Characterization of Hypoxic Alveolar Epithelial Cells After Lung Contusion Indicates an Important Role for HIF-1α

(2018) Matthew A. Sherman et al.   ANNALS OF SURGERY

Erythrocyte membrane bioinspired near-infrared persistent luminescence nanocarriers for in vivo long-circulating bioimaging and drug delivery

(2018) Jing-Min Liu et al.   BIOMATERIALS

Metformin's antitumour and anti-angiogenic activities are mediated by skewing macrophage polarization

(2018) Ji-Chang Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Cell membrane-based nanoparticles: a new biomimetic platform for tumor diagnosis and treatment

(2018) Ruixiang Li et al.   Acta Pharmaceutica Sinica B

Platelet-mimicking nanoparticles co-loaded with W18O49 and metformin alleviate tumor hypoxia for enhanced photodynamic therapy and photothermal therapy

(2018) Huaqin Zuo et al.   Acta Biomaterialia

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

(2018) Jong-Ho Cha et al.   MOLECULAR CELL

Synchronized Ratiometric Codelivery of Metformin and Topotecan through Engineered Nanocarrier Facilitates In Vivo Synergistic Precision Levels at Tumor Site

(2018) Venkatesh Teja Banala et al.   Advanced Healthcare Materials

Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3

(2018) Jun Wang et al.   CELL

Overcoming tumor hypoxia as a barrier to radiotherapy, chemotherapy and immunotherapy in cancer treatment

(2018) Kaitlin Graham et al.   International Journal of Nanomedicine

HIP1R targets PD-L1 to lysosomal degradation to alter T cell–mediated cytotoxicity

(2018) Huanbin Wang et al.   Nature Chemical Biology

Worm-Like Biomimetic Nanoerythrocyte Carrying siRNA for Melanoma Gene Therapy

(2018) Yanming Wang et al.   Small

Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity

(2018) Kathleen M. Kokolus et al.   OncoImmunology

Emerging Role of Combination Immunotherapy in the First-line Treatment of Advanced Renal Cell Carcinoma

(2018) Saby George et al.   JAMA Oncology

LAG3 (CD223) as a cancer immunotherapy target

(2017) Lawrence P. Andrews et al.   IMMUNOLOGICAL REVIEWS

The generation of compartmentalized nanoparticles containing siRNA and cisplatin using a multi-needle electrohydrodynamic strategy

(2017) Maria F. Pina et al.   Nanoscale

Hypoxic tumor microenvironment: Opportunities to develop targeted therapies

(2016) Akhil Patel et al.   BIOTECHNOLOGY ADVANCES

Dual Faces of IFN  in Cancer Progression: A Role of PD-L1 Induction in the Determination of Pro- and Antitumor Immunity

(2016) M. Mandai et al.   CLINICAL CANCER RESEARCH

Co-delivery of polymeric metformin and cisplatin by self-assembled core-membrane nanoparticles to treat non-small cell lung cancer

(2016) Yang Xiong et al.   JOURNAL OF CONTROLLED RELEASE

Colonic gene silencing using siRNA-loaded calcium phosphate/PLGA nanoparticles ameliorates intestinal inflammation in vivo

(2016) Annika Frede et al.   JOURNAL OF CONTROLLED RELEASE

Liposomes co-loaded with metformin and chlorin e6 modulate tumor hypoxia during enhanced photodynamic therapy

(2016) Xuejiao Song et al.   Nano Research

PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery

(2016) Yi Zhao et al.   Nature Communications

Biomaterials in siRNA Delivery: A Comprehensive Review

(2016) William Ho et al.   Advanced Healthcare Materials

Immune-mediated antitumor effect by type 2 diabetes drug, metformin

(2015) Shingo Eikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Tbx5 Is Required for Avian and Mammalian Epicardial Formation and Coronary Vasculogenesis

(2014) Nata Y.S.-G. Diman et al.   CIRCULATION RESEARCH

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

(2014) William W Wheaton et al.   eLife

A review of nanocarriers for the delivery of small interfering RNA

(2012) Prashant Kesharwani et al.   BIOMATERIALS

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Metal Carbonation of Forsterite in Supercritical CO2 and H2O Using Solid State 29Si, 13C NMR Spectroscopy

(2010) Ja Hun Kwak et al.   Journal of Physical Chemistry C

AMP-activated protein kinase and human cancer: cancer metabolism revisited

(2008) F P Kuhajda   INTERNATIONAL JOURNAL OF OBESITY