标题
BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 218, Issue 11, Pages -
出版商
Rockefeller University Press
发表日期
2021-09-24
DOI
10.1084/jem.20201656
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting the NLRP3 Inflammasome via BTK
- (2021) Alexander N. R. Weber Frontiers in Cell and Developmental Biology
- Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β–mediated colitis
- (2020) Liming Mao et al. JOURNAL OF CLINICAL INVESTIGATION
- Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
- (2020) Daniel P. Duarte et al. Nature Communications
- Inhibition of Bruton's tyrosine kinase regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation
- (2020) Gareth S.D. Purvis et al. BRITISH JOURNAL OF PHARMACOLOGY
- Inhibition of Bruton tyrosine kinase in patients with severe COVID-19
- (2020) Mark Roschewski et al. Science Immunology
- HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation
- (2020) Venkat Giri Magupalli et al. SCIENCE
- X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure
- (2020) Caroline E. O'Riordan et al. Frontiers in Immunology
- The NLRP3 inflammasome drives inflammation in ischemia/reperfusion injury after transient middle cerebral artery occlusion in mice
- (2020) Maximilian Franke et al. BRAIN BEHAVIOR AND IMMUNITY
- Recent insights into the regulatory networks of NLRP3 inflammasome activation
- (2020) Alexander N. R. Weber et al. JOURNAL OF CELL SCIENCE
- MCC950 closes the active conformation of NLRP3 to an inactive state
- (2019) Ana Tapia-Abellán et al. Nature Chemical Biology
- Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
- (2019) Humayun Sharif et al. NATURE
- Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice
- (2019) Caroline E. O'Riordan et al. Frontiers in Immunology
- Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming
- (2018) Jack P. Green et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation
- (2018) Jueqi Chen et al. NATURE
- Regulation of NLRP3 Inflammasome by Phosphorylation
- (2018) Nan Song et al. Frontiers in Immunology
- Bruton tyrosine kinase inhibition: Clinical relevance beyond B cells
- (2017) Balaji Banoth et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Human NACHT, LRR, and PYD domain–containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase
- (2017) Xiao Liu et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Protein kinase D at the Golgi controls NLRP3 inflammasome activation
- (2017) Zhirong Zhang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Bruton’s Tyrosine Kinase: An Emerging Key Player in Innate Immunity
- (2017) Alexander N. R. Weber et al. Frontiers in Immunology
- NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
- (2016) Marianne R. Spalinger et al. JOURNAL OF CLINICAL INVESTIGATION
- NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
- (2016) Yuan He et al. NATURE
- The Inflammasomes and Autoinflammatory Syndromes
- (2015) Lori Broderick et al. Annual Review of Pathology-Mechanisms of Disease
- A frequent hypofunctionalIRAK2variant is associated with reduced spontaneous hepatitis C virus clearance
- (2015) Hui Wang et al. HEPATOLOGY
- A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation
- (2015) Jonathan L. Schmid-Burgk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- Bruton’s tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury
- (2015) Minako Ito et al. Nature Communications
- PyTMs: a useful PyMOL plugin for modeling common post-translational modifications
- (2014) Andreas Warnecke et al. BMC BIOINFORMATICS
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
- (2013) John C. Byrd et al. NEW ENGLAND JOURNAL OF MEDICINE
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Function and dysfunction of the PI system in membrane trafficking
- (2008) Mariella Vicinanza et al. EMBO JOURNAL
- CHARMM-GUI: A web-based graphical user interface for CHARMM
- (2008) Sunhwan Jo et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
- PBEQ-Solver for online visualization of electrostatic potential of biomolecules
- (2008) Sunhwan Jo et al. NUCLEIC ACIDS RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started