In silico network pharmacology and in vivo analysis of berberine-related mechanisms against type 2 diabetes mellitus and its complications
出版年份 2021 全文链接
标题
In silico network pharmacology and in vivo analysis of berberine-related mechanisms against type 2 diabetes mellitus and its complications
作者
关键词
Network pharmacology, Berberine, Type 2 diabetes mellitus, Diabetic complications, RXRA, KCNQ1, NR3C1
出版物
JOURNAL OF ETHNOPHARMACOLOGY
Volume 276, Issue -, Pages 114180
出版商
Elsevier BV
发表日期
2021-05-04
DOI
10.1016/j.jep.2021.114180
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- All-trans retinoic acid suppresses bone morphogenetic protein 4 in mouse diabetic nephropathy through a unique retinoic acid response element
- (2019) Masanori Tamaki et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Microvascular complications among patients with diabetes: An emerging health problem in Saudi Arabia
- (2019) Asirvatham Alwin Robert et al. Diabetes & Vascular Disease Research
- KCNQ1OT1 affects the progression of diabetic retinopathy by regulating miR-1470 and epidermal growth factor receptor
- (2019) Jun Shao et al. JOURNAL OF CELLULAR PHYSIOLOGY
- A review of the molecular design and biological activities of RXR agonists
- (2019) Nathalia Rodrigues Almeida et al. MEDICINAL RESEARCH REVIEWS
- Antidiabetic Potential of Flavonoids from Traditional Chinese Medicine: A Review
- (2019) Lan Bai et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Pathophysiology of Glucocorticoid Signaling
- (2018) Géraldine Vitellius et al. ANNALES D ENDOCRINOLOGIE
- IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045
- (2018) N.H. Cho et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- The role of xenobiotic receptors on hepatic glycolipid metabolism
- (2018) Ke Chen et al. CURRENT DRUG METABOLISM
- The PI3K/AKT pathway in obesity and type 2 diabetes
- (2018) Xingjun Huang et al. International Journal of Biological Sciences
- Retinoid X Receptor Antagonists
- (2018) Masaki Watanabe et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Aldosterone Hypothesis for Cognitive Impairment in Diabetes Mellitus
- (2017) Sarama Saha et al. HORMONE AND METABOLIC RESEARCH
- Retinoic acid improves nephrotoxic serum–induced glomerulonephritis through activation of podocyte retinoic acid receptor α
- (2017) Yan Dai et al. KIDNEY INTERNATIONAL
- System Pharmacology-Based Dissection of the Synergistic Mechanism of Huangqi and Huanglian for Diabetes Mellitus
- (2017) Shi-Jun Yue et al. Frontiers in Pharmacology
- Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding
- (2017) Yachen Shen et al. Molecular Metabolism
- The glucocorticoid receptor: cause of or cure for obesity?
- (2016) Kezia John et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Fatty Acid Oxidation and Its Relation with Insulin Resistance and Associated Disorders
- (2016) Gary D. Lopaschuk ANNALS OF NUTRITION AND METABOLISM
- Drug Repositioning Through Network Pharmacology
- (2016) Hao Ye et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Risk factors for post-transplant diabetes mellitus in renal transplant: Role of genetic variability in the CYP450-mediated arachidonic acid metabolism
- (2016) Guillermo Gervasini et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Metabolomics Study of Type 2 Diabetes Mellitus and the AntiDiabetic Effect of Berberine in Zucker Diabetic Fatty Rats Using Uplc-ESI-Hdms
- (2016) Yu Dong et al. PHYTOTHERAPY RESEARCH
- Attenuation of Streptozotocin-Induced Lipid Profile Anomalies in the Heart, Brain, and mRNA Expression of HMG-CoA Reductase by Diosgenin in Rats
- (2015) Shuang Hao et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Tadehaginoside modulates lipogenesis and glucose consumption in HepG2 cells
- (2015) Xiaopo Zhang et al. NATURAL PRODUCT RESEARCH
- Type 2 diabetes mellitus
- (2015) Ralph A. DeFronzo et al. Nature Reviews Disease Primers
- Uncoupling protein-2 mediates the protective action of berberine against oxidative stress in rat insulinoma INS-1E cells and in diabetic mouse islets
- (2014) Limei Liu et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities
- (2014) Miranda T. Schram et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- The protective effect of berberine on β-cell lipoapoptosis
- (2014) N. Gao et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review
- (2014) Bogna Grygiel-Górniak Nutrition Journal
- Berberine metabolites exhibit triglyceride-lowering effects via activation of AMP-activated protein kinase in Hep G2 cells
- (2013) Shijie Cao et al. JOURNAL OF ETHNOPHARMACOLOGY
- Microarray Analyses of Glucocorticoid and Vitamin D3 Target Genes in Differentiating Cultured Human Podocytes
- (2013) Xiwen Cheng et al. PLoS One
- Genetic and epigenetic control of metabolic health
- (2013) Robert Wolfgang Schwenk et al. Molecular Metabolism
- Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model
- (2012) Qian Zhang et al. Journal of Natural Medicines
- Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isoforms
- (2012) Penelope M.Y. Or et al. PHYTOMEDICINE
- Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus
- (2011) Miroslav Dostalek et al. BRITISH JOURNAL OF PHARMACOLOGY
- Sleep Architecture and Glucose and Insulin Homeostasis in Obese Adolescents
- (2011) D. Koren et al. DIABETES CARE
- Repeated administration of berberine inhibits cytochromes P450 in humans
- (2011) Ying Guo et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- High glucose impairs EDHF-mediated dilation of coronary arterioles via reduced cytochrome P450 activity
- (2011) Shu-Huai Tsai et al. MICROVASCULAR RESEARCH
- Diabetes is an inflammatory disease: evidence from traditional Chinese medicines
- (2010) W. Xie et al. DIABETES OBESITY & METABOLISM
- Beneficial effect of berberine on hepatic insulin resistance in diabetic hamsters possibly involves in SREBPs, LXRα and PPARα transcriptional programs
- (2010) Xuhan Liu et al. ENDOCRINE JOURNAL
- Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes
- (2010) Jiyin Zhou et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Berberine improves free-fatty-acid–induced insulin resistance in L6 myotubes through inhibiting peroxisome proliferator–activated receptor γ and fatty acid transferase expressions
- (2009) Yanfeng Chen et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression
- (2009) Hao Zhang et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Chronic Effects of Berberine on Blood, Liver Glucolipid Metabolism and Liver PPARs Expression in Diabetic Hyperlipidemic Rats
- (2008) Ji Yin Zhou et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Efficacy of berberine in patients with type 2 diabetes mellitus
- (2008) Jun Yin et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
- Role ofCYP2C9 andCYP2C19 polymorphisms in patients with atherosclerosis
- (2007) B. Ercan et al. CELL BIOCHEMISTRY AND FUNCTION
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now