Cascade of Inflammatory, Fibrotic Processes, and Stress-Induced Senescence in Chronic GVHD-Related Dry Eye Disease

The Association between Meibomian Gland Atrophy and Corneal Subbasal Nerve Loss in Patients with Chronic Ocular Graft-versus-host Disease

(2021) Ozlem Dikmetas et al.   CURRENT EYE RESEARCH

Positive Effects of Oral Antibiotic Administration in Murine Chronic Graft-Versus-Host Disease

(2021) Shinri Sato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Eye amputation following lifitegrast treatment for ocular graft-versus-host disease: First case report

(2021) T. Ferrete et al.   JOURNAL FRANCAIS D OPHTALMOLOGIE

Two case reports of continued progression of chronic ocular graft-versus-host disease without concurrent systemic comorbidities treated by amniotic membrane transplantation

(2021) Hideto Ikarashi et al.   BMC Ophthalmology

IL6-receptor antibody tocilizumab as salvage therapy in severe chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: a retrospective analysis

(2020) Anna-Sophia Kattner et al.   ANNALS OF HEMATOLOGY

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

(2020) Josef S Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Adverse environmental conditions are a risk factor for ocular GvHD after allogeneic hematopoietic stem cell transplantation

(2020) P. Steven et al.   BONE MARROW TRANSPLANTATION

Tear cytokine levels in the diagnosis and severity assessment of ocular chronic graft-versus-host disease(GVHD)

(2020) Bohao Hu et al.   Ocular Surface

Dupilumab-Associated Mucin Deficiency (DAMD)

(2020) Brad P. Barnett et al.   Translational Vision Science & Technology

DNA methylation of miR-200 clusters promotes epithelial to mesenchymal transition in human conjunctival epithelial cells

(2020) Jovana Rajić et al.   EXPERIMENTAL EYE RESEARCH

Guidelines and definitions for research on epithelial–mesenchymal transition

(2020) Jing Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Comparison of the ocular microbiome between chronic Stevens-Johnson syndrome patients and healthy subjects

(2020) Thanachaporn Kittipibul et al.   Scientific Reports

Senescence‐associated secretory phenotype promotes chronic ocular graft‐vs‐host disease in mice and humans

(2020) Mio Yamane et al.   FASEB JOURNAL

T Cells in Fibrosis and Fibrotic Diseases

(2020) Mengjuan Zhang et al.   Frontiers in Immunology

Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease

(2020) Volkan Tahmaz et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Disease-Specific Expression of Conjunctiva Associated Lymphoid Tissue (CALT) in Mouse Models of Dry Eye Disease and Ocular Allergy

(2020) Philipp Steven et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Assessing the ocular surface microbiome in severe ocular surface diseases

(2020) Michael J. Zilliox et al.   Ocular Surface

Helper Innate Lymphoid Cells in Allogenic Hematopoietic Stem Cell Transplantation and Graft Versus Host Disease

(2020) Linda Quatrini et al.   Frontiers in Immunology

The Overlap Syndrome

(2020) Shunsuke Hayashi et al.   CORNEA

Subconjunctival injection of mesenchymal stromal cells protects the cornea in an experimental model of GVHD

(2019) Rafael Martínez-Carrasco et al.   Ocular Surface

Commensal microflora in human conjunctiva; characteristics of microflora in the patients with chronic ocular graft-versus-host disease

(2019) Eisuke Shimizu et al.   Ocular Surface

Tocilizumab as first-line therapy for steroid-refractory acute graft-versus-host-disease: analysis of a single-center experience

(2019) Filiz Yucebay et al.   LEUKEMIA & LYMPHOMA

Ocular surface system alterations in ocular graft-versus-host disease: all the pieces of the complex puzzle

(2019) Giuseppe Giannaccare et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies

(2019) Seungwon An et al.   Ocular Surface

Longitudinal analysis of meibomian gland dropout in patients with ocular graft-versus-host disease

(2019) Ho Sik Hwang et al.   Ocular Surface

Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease

(2019) M. Hanief Sofi et al.   JOURNAL OF CLINICAL INVESTIGATION

An Essential Role of Innate Lymphoid Cells in the Pathophysiology of Graft-vs.-Host Disease

(2019) Liang Shao et al.   Frontiers in Immunology

Lifitegrast ophthalmic solution for treatment of ocular chronic graft-versus-host disease

(2019) Saurabh Chhabra et al.   LEUKEMIA & LYMPHOMA

Pathological consequences of anti-citrullinated protein antibodies in tear fluid and therapeutic potential of pooled human immune globulin-eye drops in dry eye disease

(2019) Jieun Kwon et al.   Ocular Surface

The primacy of gastrointestinal tract antigen-presenting cells in lethal graft-versus-host disease

(2019) Motoko Koyama et al.   BLOOD

The secretome of adipose-derived mesenchymal stem cells attenuates epithelial–mesenchymal transition in human corneal epithelium

(2019) Shun Shibata et al.   Regenerative Therapy

Reduced Efficacy of Low-dose Topical Steroids in Dry Eye Disease Associated With Graft-versus-Host Disease

(2018) Jia Yin et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Ocular Surface and Tear Film Characteristics in a Sclerodermatous Chronic Graft-Versus-Host Disease Mouse Model

(2018) Jingliang He et al.   CORNEA

Inhibition of Vascular Adhesion Protein-1 for Treatment of Graft-Versus-Host Disease in Mice

(2018) Shin Mukai et al.   FASEB JOURNAL

Tear inflammatory mediators and protein in eyes of post allogenic hematopoeitic stem cell transplant patients

(2018) Sridevi Nair et al.   Ocular Surface

Oxysterol Signatures Distinguish Age-Related Macular Degeneration from Physiologic Aging

(2018) Jonathan B. Lin et al.   EBioMedicine

Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice

(2018) Shin Mukai et al.   PLoS One

Ocular graft-versus-host disease after hematopoietic cell transplantation: Expert review from the Late Effects and Quality of Life Working Committee of the CIBMTR and Transplant Complications Working Party of the EBMT

(2018) Yoshihiro Inamoto et al.   BONE MARROW TRANSPLANTATION

Topical Cyclosporine Pretreatment of Ocular Surface in Allogeneic Hematopoietic Stem Cell Transplant Recipients

(2018) Yoon Hong Chun et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

A novel and innovative paper-based analytical device for assessing tear lactoferrin of dry eye patients

(2018) Hideki Sonobe et al.   Ocular Surface

Marked infiltration of neutrophils at the upper palpebral conjunctiva in patients with chronic graft-versus-host disease

(2018) Yong-Soo Byun et al.   Ocular Surface

Changes of meibomian glands in the early stage of post hematopoietic stem cell transplantation

(2017) Seonjoo Kim et al.   EXPERIMENTAL EYE RESEARCH

Long-Term Topical Diquafosol Tetrasodium Treatment of Dry Eye Disease Caused by Chronic Graft-Versus-Host Disease

(2017) Mio Yamane et al.   Eye & Contact Lens-Science and Clinical Practice

Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy

(2017) Robert Zeiser et al.   NEW ENGLAND JOURNAL OF MEDICINE

TFOS DEWS II Tear Film Report

(2017) Mark D.P. Willcox et al.   Ocular Surface

TFOS DEWS II pathophysiology report

(2017) Anthony J. Bron et al.   Ocular Surface

TFOS DEWS II Management and Therapy Report

(2017) Lyndon Jones et al.   Ocular Surface

A Case of a Bilateral Cicatricial Upper Eyelid Entropion After Hematopoietic Stem Cell Transplantation in Mucopolysaccharidosis Type I

(2017) Simon Dulz et al.   OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY

A Review of Ocular Graft-Versus-Host Disease

(2017) Saleha Z. Munir et al.   OPTOMETRY AND VISION SCIENCE

Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease

(2017) Yoko Ogawa et al.   Scientific Reports

Novel Treatment of Chronic Graft-Versus-Host Disease in Mice Using the ER Stress Reducer 4-Phenylbutyric Acid

(2017) Shin Mukai et al.   Scientific Reports

In Vivo Confocal Microscopy Evaluation of Ocular Surface with Graft-Versus-Host Disease-Related Dry Eye Disease

(2017) Jingliang He et al.   Scientific Reports

Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review

(2016) Cesar Daniel Villarreal Villarreal et al.   ANAIS BRASILEIROS DE DERMATOLOGIA

Novel Scoring Criteria for the Evaluation of Ocular Graft-versus-Host Disease in a Preclinical Allogeneic Hematopoietic Stem Cell Transplantation Animal Model

(2016) Victor L. Perez et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Long-term safety and efficacy of autologous platelet lysate drops for treatment of ocular GvHD

(2016) S Pezzotta et al.   BONE MARROW TRANSPLANTATION

Treatment of severe chronic ocular graft-versus-host disease using 100% autologous serum eye drops from a sealed manufacturing system: a retrospective cohort study

(2016) Volkan Tahmaz et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

PROSE Treatment for Ocular Chronic Graft-Versus-Host Disease as a Clinical Network Expands

(2016) Karen S. DeLoss et al.   Eye & Contact Lens-Science and Clinical Practice

A Novel Technique for Amniotic Membrane Transplantation in Patients with Acute Stevens-Johnson Syndrome

(2016) Kelly N. Ma et al.   Ocular Surface

A Clinical Trial Comparing the Safety and Efficacy of Topical Tacrolimus versus Methylprednisolone in Ocular Graft-versus-Host Disease

(2016) Tulio B. Abud et al.   OPHTHALMOLOGY

Mitochondria-targeted antioxidant SkQ1 reduces age-related alterations in the ultrastructure of the lacrimal gland

(2016) Lora E. Bakeeva et al.   Oncotarget

MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model

(2016) Yoko Ogawa et al.   eLife

NK Cells and Other Innate Lymphoid Cells in Hematopoietic Stem Cell Transplantation

(2016) Paola Vacca et al.   Frontiers in Immunology

The role of inflammation in age-related disease

(2016) T. Kevin Howcroft et al.   Aging-US

Altered Mucosal Microbiome Diversity and Disease Severity in Sjögren Syndrome

(2016) Cintia S. de Paiva et al.   Scientific Reports

Long-term Result of Maintenance Treatment With Tacrolimus Ointment in Chronic Ocular Graft-Versus-Host Disease

(2015) Ji Won Jung et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Innate Lymphoid Cells in Graft-Versus-Host Disease

(2015) V. Konya et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Bandage Soft Contact Lenses for Ocular Graft-versus-Host Disease

(2015) Yoshihiro Inamoto et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Tear Cytokines as Biomarkers for Chronic Graft-versus-Host Disease

(2015) Ji Won Jung et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group Report

(2015) Madan H. Jagasia et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Meibography and meibomian gland measurements in ocular graft-versus-host disease

(2015) L A Engel et al.   BONE MARROW TRANSPLANTATION

Human Bone Marrow Stromal Cells Differentiate into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice

(2015) Luis Ignacio Sánchez-Abarca et al.   CELL TRANSPLANTATION

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms

(2015) Flora Brozzi et al.   DIABETOLOGIA

Semifluorinated Alkane Eye Drops for Treatment of Dry Eye Disease—A Prospective, Multicenter Noninterventional Study

(2015) Philipp Steven et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Long-term Rebamipide and Diquafosol in Two Cases of Immune-Mediated Dry Eye

(2015) Mio Yamane et al.   OPTOMETRY AND VISION SCIENCE

Tranilast: A review of its therapeutic applications

(2015) Sara Darakhshan et al.   PHARMACOLOGICAL RESEARCH

Cytokine profile of autologous platelet-derived eye drops in patients with ocular chronic graft-versus-host disease

(2015) C. G. Valentini et al.   VOX SANGUINIS

Immunomodulatory Cross-Talk between Conjunctival Goblet Cells and Dendritic Cells

(2015) Laura Contreras-Ruiz et al.   PLoS One

Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease

(2014) J. M. Munneke et al.   BLOOD

The impact of age-related dysregulation of the angiotensin system on mitochondrial redox balance

(2014) Ramya Vajapey et al.   Frontiers in Physiology

Plasma CXCL9 elevations correlate with chronic GVHD diagnosis

(2013) C. L. Kitko et al.   BLOOD

Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation

(2013) Maria Ester Bernardo et al.   Cell Stem Cell

Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye

(2013) Xiaobo Zhang et al.   EXPERIMENTAL EYE RESEARCH

Graft versus host disease: clinical evaluation, diagnosis and management

(2013) Edgar M. Espana et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Dry Eye as a Mucosal Autoimmune Disease

(2013) Michael E. Stern et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Modulation of Conjunctival Goblet Cell Function by Inflammatory Cytokines

(2013) L. Contreras-Ruiz et al.   MEDIATORS OF INFLAMMATION

Chronic dry eye disease is principally mediated by effector memory Th17 cells

(2013) Y Chen et al.   Mucosal Immunology

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Dry Eye Disease and Microbial Keratitis: Is There a Connection?

(2013) Srihari Narayanan et al.   Ocular Surface

Angiotensin II Type 1 Receptor Antagonist Attenuates Lacrimal Gland, Lung, and Liver Fibrosis in a Murine Model of Chronic Graft-Versus-Host Disease

(2013) Saori Yaguchi et al.   PLoS One

Ocular Graft-versus-Host Disease: A Review

(2013) Hasanain Shikari et al.   SURVEY OF OPHTHALMOLOGY

Expression and localization of aging markers in lacrimal gland of chronic graft-versus-host disease

(2013) Masataka Kawai et al.   Scientific Reports

Topical Interleukin 1 Receptor Antagonist for Treatment of Dry Eye Disease

(2013) Francisco Amparo et al.   JAMA Ophthalmology

Dry Eye Disease

(2012) William Stevenson   ARCHIVES OF OPHTHALMOLOGY

Surgical management of lacrimal punctal cauterization in chronic GVHD-related dry eye with recurrent punctal plug extrusion

(2012) S Yaguchi et al.   BONE MARROW TRANSPLANTATION

TXNIP Switches Tracks toward a Terminal UPR

(2012) Tracy G. Anthony et al.   Cell Metabolism

Ocular graft-versus-host disease

(2012) Michelle Hessen et al.   Current Opinion in Allergy and Clinical Immunology

Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production

(2012) Yuichi Uchino et al.   PLoS One

ER stress-induced inflammation: does it aid or impede disease progression?

(2012) Abhishek D. Garg et al.   TRENDS IN MOLECULAR MEDICINE

Suppression of human CD4+ T cell activation by 3,4-dimethoxycinnamonyl-anthranilic acid (tranilast) is mediated by CXCL9 and CXCL10

(2011) Anne Hertenstein et al.   BIOCHEMICAL PHARMACOLOGY

Punctal occlusion is safe and efficient for the treatment of keratoconjunctivitis sicca in patients with ocular GvHD

(2011) S Sabti et al.   BONE MARROW TRANSPLANTATION

Mucosal microvilli in dry eye patients with chronic GVHD

(2011) Y Tatematsu et al.   BONE MARROW TRANSPLANTATION

Comparison of stem cell sources in the severity of dry eye after allogeneic haematopoietic stem cell transplantation

(2011) Miki Uchino et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Visual Acuity and Anterior Segment Findings in Chronic Graft-Versus-Host Disease

(2011) Evan J Allan et al.   CORNEA

Diagnosis and Treatment of Ocular Chronic Graft-Versus-Host Disease: Report From the German–Austrian–Swiss Consensus Conference on Clinical Practice in Chronic GVHD

(2011) Tina Dietrich-Ntoukas et al.   CORNEA

Danger signals activating innate immunity in graft-versus-host disease

(2011) Robert Zeiser et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Current insights into ocular graft-versus-host disease

(2010) Anjo Riemens et al.   CURRENT OPINION IN OPHTHALMOLOGY

Angiotensin II revisited: new roles in inflammation, immunology and aging

(2010) Ariela Benigni et al.   EMBO Molecular Medicine

Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13

(2010) C S De Paiva et al.   Mucosal Immunology

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Extracorporeal photochemotherapy in graft-versus-host disease: a longitudinal study on factors influencing the response and survival in pediatric patients

(2010) Cesare Perotti et al.   TRANSFUSION

Epithelial Mesenchymal Transition in Human Ocular Chronic Graft-Versus-Host Disease

(2009) Yoko Ogawa et al.   AMERICAN JOURNAL OF PATHOLOGY

Baseline profiles of ocular surface and tear dynamics after allogeneic hematopoietic stem cell transplantation in patients with or without chronic GVHD-related dry eye

(2009) Y Wang et al.   BONE MARROW TRANSPLANTATION

Topical tranilast for treatment of the early stage of mild dry eye associated with chronic GVHD

(2009) Y Ogawa et al.   BONE MARROW TRANSPLANTATION

Innate immunity of the ocular surface

(2009) Mayumi Ueta et al.   BRAIN RESEARCH BULLETIN

Ocular Surface Reconstruction in Graft-Versus-Host Disease With HLA-Identical Living-Related Allogeneic Cultivated Limbal Epithelium After Hematopoietic Stem Cell Transplantation From the Same Donor

(2009) Daniel Meller et al.   CORNEA

The role of microbial flora on the ocular surface

(2009) Darlene Miller et al.   Current Opinion in Allergy and Clinical Immunology

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

A multicenter prospective phase 2 randomized study of extracorporeal photopheresis for treatment of chronic graft-versus-host disease

(2008) M. E. D. Flowers et al.   BLOOD

Ischemia-reperfusion injury is attenuated in VAP-1-deficient mice and by VAP-1 inhibitors

(2008) Jan Kiss et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Collagen I Promotes Epithelial-to-Mesenchymal Transition in Lung Cancer Cells via Transforming Growth Factor–β Signaling

(2007) Yasushi Shintani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY