标题
Organoids in modelling infectious diseases
作者
关键词
Organoids, Infectious diseases, Infection, Drug screening, Viruses, Bacteria, Protists
出版物
DRUG DISCOVERY TODAY
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2021-08-19
DOI
10.1016/j.drudis.2021.08.005
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- An update to “novel therapeutic approaches for treatment of COVID-19”
- (2021) Nikoo Hossein-khannazer et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- A host cell long noncoding RNA NR_033736 regulates type I interferon-mediated gene transcription and modulates intestinal epithelial anti-Cryptosporidium defense
- (2021) Juan Li et al. PLoS Pathogens
- Evolution of organoid technology: Lessons learnt in Co-Culture systems from developmental biology
- (2021) Ensieh Zahmatkesh et al. DEVELOPMENTAL BIOLOGY
- Harmonization of Protocols for Multi-Species Organoid Platforms to Study the Intestinal Biology of Toxoplasma gondii and Other Protozoan Infections
- (2021) David Holthaus et al. Frontiers in Cellular and Infection Microbiology
- Effect of Listeria monocytogenes on intestinal stem cells in the co-culture model of small intestinal organoids
- (2021) Jie Huang et al. MICROBIAL PATHOGENESIS
- Gastrointestinal tract modeling using organoids engineered with cellular and microbiota niches
- (2020) Sungjin Min et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells
- (2020) Aditya Mithal et al. Nature Communications
- Development of Novel Anti-influenza Thiazolides with Relatively Broad-spectrum Antiviral Potentials
- (2020) Lei Zhao et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
- (2020) Vanessa Monteil et al. CELL
- Optical Metabolic Imaging (OMI) of Toxoplasma gondii and Cryptosporidium parvum in a 3D system
- (2020) Cerise Marie Siamof et al. FASEB JOURNAL
- Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process
- (2020) Hao Zhang et al. GUT
- Infection of bat and human intestinal organoids by SARS-CoV-2
- (2020) Jie Zhou et al. NATURE MEDICINE
- SARS-CoV-2 productively infects human gut enterocytes
- (2020) Mart M. Lamers et al. SCIENCE
- Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids
- (2020) Bing Zhao et al. Protein & Cell
- Decellularized Tissue Matrix Enhances Self-Assembly of Islet Organoids from Pluripotent Stem Cell Differentiation
- (2020) Huanjing Bi et al. ACS Biomaterials-Science & Engineering
- Salmonella Enteritidis Effector AvrA Suppresses Autophagy by Reducing Beclin-1 Protein
- (2020) Yang Jiao et al. Frontiers in Immunology
- TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
- (2020) Ruochen Zang et al. Science Immunology
- A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
- (2020) Liuliu Yang et al. Cell Stem Cell
- Novel therapeutic approaches for treatment of COVID-19
- (2020) Nikoo Hossein-khannazer et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Brain Organoids: Tiny Mirrors of Human Neurodevelopment and Neurological Disorders
- (2020) Anuradha Yadav et al. NEUROSCIENTIST
- Mechano-modulatory synthetic niches for liver organoid derivation
- (2020) Giovanni Sorrentino et al. Nature Communications
- Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids
- (2020) Maria-Patapia Zafeiriou et al. Nature Communications
- Murine Endometrial Organoids to Model Chlamydia Infection
- (2020) R. Clayton Bishop et al. Frontiers in Cellular and Infection Microbiology
- Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by Immunostaining
- (2020) Teresa P. Silva et al. Jove-Journal of Visualized Experiments
- Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase
- (2020) Robert M. Cox et al. Nature Microbiology
- Organoid technology demonstrates effects of potential drugs for COVID‐19 on the lung regeneration
- (2020) Jianhai Wang et al. CELL PROLIFERATION
- SARS ‐CoV‐2 targets neurons of 3D human brain organoids
- (2020) Anand Ramani et al. EMBO JOURNAL
- In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
- (2020) Jiyoung Lee et al. Nature Communications
- Modeling HIV-1 neuropathogenesis using three-dimensional human brain organoids (hBORGs) with HIV-1 infected microglia
- (2020) Roberta S. dos Reis et al. Scientific Reports
- Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes
- (2020) Haowen Qiao et al. PLoS Pathogens
- Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo
- (2020) Zhong Li et al. Emerging Microbes & Infections
- Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection
- (2020) Vanessa Monteil et al. EMBO Molecular Medicine
- Long‐term expanding human airway organoids for disease modeling
- (2019) Norman Sachs et al. EMBO JOURNAL
- Evaluating S. flexneri pathogenesis in the human enteroid model
- (2019) Sridevi Ranganathan et al. INFECTION AND IMMUNITY
- Engineering Microfluidic Organoid-on-a-Chip Platforms
- (2019) Fang Yu et al. Micromachines
- Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection
- (2019) Loryn Holokai et al. PLoS Pathogens
- Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation
- (2019) Mirjana Kessler et al. Nature Communications
- Flow-enhanced vascularization and maturation of kidney organoids in vitro
- (2019) Kimberly A. Homan et al. NATURE METHODS
- Modeling HSV-1 infections in human CNS neuronal cells using two-dimensional and three- dimensional cultures derived from induced pluripotent stem cells
- (2019) Leonardo D'Aiuto et al. JOURNAL OF VIROLOGY
- Biologically inspired approaches to enhance human organoid complexity
- (2019) Emily M. Holloway et al. DEVELOPMENT
- Tropism of influenza B viruses in human respiratory tract explants and airway organoids
- (2019) Christine H.T. Bui et al. EUROPEAN RESPIRATORY JOURNAL
- Self-organization and symmetry breaking in intestinal organoid development
- (2019) Denise Serra et al. NATURE
- Authentic Modeling of Human Respiratory Virus Infection in Human Pluripotent Stem Cell-Derived Lung Organoids
- (2019) M. Porotto et al. mBio
- 3D bioprinted mammary organoids and tumoroids in human mammary derived ECM hydrogels
- (2019) Peter A. Mollica et al. Acta Biomaterialia
- A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability
- (2019) Georgia Wilke et al. Cell Host & Microbe
- Association Between Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infection in Early Life and Recurrent Wheeze and Asthma in Later Childhood
- (2019) Ting Shi et al. JOURNAL OF INFECTIOUS DISEASES
- Human Cytomegalovirus Disruption of Calcium Signaling in Neural Progenitor Cells and Organoids
- (2019) Samantha L. Sison et al. JOURNAL OF VIROLOGY
- Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells
- (2019) Giuseppe Pettinato et al. Scientific Reports
- Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture
- (2019) Joo Hyun Jee et al. Stem Cells International
- Risk of Childhood Wheeze and Asthma after Respiratory Syncytial Virus Infection in Full‐Term Infants
- (2019) Asuncion Mejias et al. PEDIATRIC ALLERGY AND IMMUNOLOGY
- Accelerated photoreceptor differentiation of hiPSC-derived retinal organoids by contact co-culture with retinal pigment epithelium
- (2019) Tasneem Akhtar et al. Stem Cell Research
- An Open-Format Enteroid Culture System for Interrogation of Interactions Between Toxoplasma gondii and the Intestinal Epithelium
- (2019) Lisa Luu et al. Frontiers in Cellular and Infection Microbiology
- The Antibiotic Bacitracin Protects Human Intestinal Epithelial Cells and Stem Cell-Derived Intestinal Organoids from Clostridium difficile Toxin TcdB
- (2019) Ziyu Zhu et al. Stem Cells International
- Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors
- (2019) Wu et al. Cells
- Generation of Organized Porcine Testicular Organoids in Solubilized Hydrogels from Decellularized Extracellular Matrix
- (2019) Maxime Vermeulen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tailoring the collagen film structural properties via direct laser crosslinking of star-shaped polylactide for robust scaffold formation
- (2019) K.N. Bardakova et al. Materials Science & Engineering C-Materials for Biological Applications
- Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture
- (2019) Giovanni Giuseppe Giobbe et al. Nature Communications
- Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids
- (2019) Adriana Harbuzariu et al. Scientific Reports
- Designing Peptide/Graphene Hybrid Hydrogels through Fine-Tuning of Molecular Interactions
- (2018) Jacek K. Wychowaniec et al. BIOMACROMOLECULES
- Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process
- (2018) Yasmine Baktash et al. Cell Host & Microbe
- Intestinal epithelial Caspase-8 signaling is essential to prevent necroptosis during Salmonella Typhimurium induced enteritis
- (2018) Manuela Hefele et al. Mucosal Immunology
- An in vivo model of functional and vascularized human brain organoids
- (2018) Abed AlFatah Mansour et al. NATURE BIOTECHNOLOGY
- Differentiated human airway organoids to assess infectivity of emerging influenza virus
- (2018) Jie Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tailoring the mechanical properties of gelatin methacryloyl hydrogels through manipulation of the photocrosslinking conditions
- (2018) Cathal D. O'Connell et al. Soft Matter
- Engineering stem cell-derived 3D brain organoids in a perfusable organ-on-a-chip system
- (2018) Yaqing Wang et al. RSC Advances
- Basal interferon signaling and therapeutic use of interferons in controlling rotavirus infection in human intestinal cells and organoids
- (2018) Mohamad S. Hakim et al. Scientific Reports
- Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids
- (2018) Jiyoon Lee et al. Cell Reports
- Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures
- (2018) Kenrie P Y Hui et al. Lancet Respiratory Medicine
- Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids
- (2018) Ran-Ran Zhang et al. Stem Cell Reports
- Modelling Cryptosporidium infection in human small intestinal and lung organoids
- (2018) Inha Heo et al. Nature Microbiology
- Cellulose-based scaffolds for fluorescence lifetime imaging-assisted tissue engineering
- (2018) Neil O'Donnell et al. Acta Biomaterialia
- Progress and potential in organoid research
- (2018) Giuliana Rossi et al. NATURE REVIEWS GENETICS
- Recapitulation of hepatitis B virus–host interactions in liver organoids from human induced pluripotent stem cells
- (2018) Yun-Zhong Nie et al. EBioMedicine
- Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
- (2018) Huili Hu et al. CELL
- Bacteriophage Therapy Testing against Shigella flexneri in a Novel Human Intestinal Organoid-Derived Infection Model
- (2018) Alejandro Llanos-Chea et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Trophoblast organoids as a model for maternal–fetal interactions during human placentation
- (2018) Margherita Y. Turco et al. NATURE
- Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis
- (2018) Pedro H. V. Saavedra et al. Nature Communications
- Guided self-organization and cortical plate formation in human brain organoids
- (2017) Madeline A Lancaster et al. NATURE BIOTECHNOLOGY
- Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium
- (2017) Margherita Y. Turco et al. NATURE CELL BIOLOGY
- A three-dimensional model of human lung development and disease from pluripotent stem cells
- (2017) Ya-Wen Chen et al. NATURE CELL BIOLOGY
- Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
- (2017) Miguel Crespo et al. NATURE MEDICINE
- Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions
- (2017) Sacha Reichman et al. STEM CELLS
- Controlled Self-assembly of Stem Cell Aggregates Instructs Pluripotency and Lineage Bias
- (2017) Angela W. Xie et al. Scientific Reports
- Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection
- (2017) Momoko Watanabe et al. Cell Reports
- Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells
- (2017) Takanori Takebe et al. Cell Reports
- Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids
- (2017) Ying Qu et al. Stem Cell Reports
- Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine
- (2017) Christopher R. Schlieve et al. Stem Cell Reports
- Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus
- (2017) Jie Zhou et al. Science Advances
- The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication
- (2017) Carolina Q. Sacramento et al. Scientific Reports
- The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact
- (2016) Phillipe Boeuf et al. BMC Medicine
- Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3
- (2016) Jason Dang et al. Cell Stem Cell
- The Brazilian Zika virus strain causes birth defects in experimental models
- (2016) Fernanda R. Cugola et al. NATURE
- Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
- (2016) Miao Xu et al. NATURE MEDICINE
- Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
- (2016) Laura Broutier et al. Nature Protocols
- Respiratory syncytial virus hospitalization and mortality: Systematic review and meta-analysis
- (2016) Renato T. Stein et al. PEDIATRIC PULMONOLOGY
- Replication of human noroviruses in stem cell-derived human enteroids
- (2016) K. Ettayebi et al. SCIENCE
- Genetic variation of hepatitis B virus and its significance for pathogenesis
- (2016) Zhen-Hua Zhang WORLD JOURNAL OF GASTROENTEROLOGY
- Zika Fetal Neuropathogenesis: Etiology of a Viral Syndrome
- (2016) Zachary A. Klase et al. PLoS Neglected Tropical Diseases
- Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair
- (2016) Jennifer Quantius et al. PLoS Pathogens
- Modeling rotavirus infection and antiviral therapy using primary intestinal organoids
- (2015) Yuebang Yin et al. ANTIVIRAL RESEARCH
- Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
- (2015) Minoru Takasato et al. NATURE
- Nephron organoids derived from human pluripotent stem cells model kidney development and injury
- (2015) Ryuji Morizane et al. NATURE BIOTECHNOLOGY
- The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids
- (2015) Mirjana Kessler et al. Nature Communications
- In vitro generation of human pluripotent stem cell derived lung organoids
- (2015) Briana R Dye et al. eLife
- Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures
- (2014) Wouter R. Karthaus et al. CELL
- Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
- (2014) Kyle W. McCracken et al. NATURE
- Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells
- (2013) Atsuhiro Taguchi et al. Cell Stem Cell
- Vascularized and functional human liver from an iPSC-derived organ bud transplant
- (2013) Takanori Takebe et al. NATURE
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Generation of Functional Hepatocyte-Like Cells from Human Pluripotent Stem Cells in a Scalable Suspension Culture
- (2013) Massoud Vosough et al. STEM CELLS AND DEVELOPMENT
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Isolation and in vitro expansion of human colonic stem cells
- (2011) Peter Jung et al. NATURE MEDICINE
- Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
- (2010) Jason R. Spence et al. NATURE
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