Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse

Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs

(2019) Agata P. Zielinska et al.   CURRENT BIOLOGY

Tetraploidy causes chromosomal instability in acentriolar mouse embryos

(2019) Lia Mara Gomes Paim et al.   Nature Communications

Segregating Chromosomes in the Mammalian Oocyte

(2018) Aleksandar I. Mihajlović et al.   CURRENT BIOLOGY

Tri-directional anaphases as a novel chromosome segregation defect in human oocytes

(2017) Jenna Haverfield et al.   HUMAN REPRODUCTION

Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors

(2017) Jessica Greaney et al.   HUMAN REPRODUCTION UPDATE

Mechanisms of Aneuploidy in Human Eggs

(2017) Alexandre Webster et al.   TRENDS IN CELL BIOLOGY

Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes

(2015) Z. Holubcova et al.   SCIENCE

Meiosis and Maternal Aging: Insights from Aneuploid Oocytes and Trisomy Births

(2015) Mary Herbert et al.   Cold Spring Harbor Perspectives in Biology

Bivalent separation into univalents precedes age-related meiosis I errors in oocytes

(2015) Yogo Sakakibara et al.   Nature Communications

Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect

(2015) Agata P Zielinska et al.   eLife

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target

(2015) Mourad Sanhaji et al.   Oncotarget

Kinetochore microtubule establishment is defective in oocytes from aged mice

(2014) Maria Shomper et al.   CELL CYCLE

Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C

(2014) Katharine L. Sackton et al.   NATURE

Premature dyad separation in meiosis II is the major segregation error with maternal age in mouse oocytes

(2013) Y. Yun et al.   DEVELOPMENT

New insights on the origin and relevance of aneuploidy in human spermatozoa

(2013) C. Templado et al.   MOLECULAR HUMAN REPRODUCTION

Live visualization of chromatin dynamics with fluorescent TALEs

(2013) Yusuke Miyanari et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromosome cohesion decreases in human eggs with advanced maternal age

(2012) Francesca E. Duncan et al.   AGING CELL

Cytokinesis in Animal Cells

(2012) Rebecca A. Green et al.   Annual Review of Cell and Developmental Biology

Lack of response to unaligned chromosomes in mammalian female gametes

(2012) Jaroslava Sebestova et al.   CELL CYCLE

Checkpoint-Independent Stabilization of Kinetochore-Microtubule Attachments by Mad2 in Human Cells

(2012) Lilian Kabeche et al.   CURRENT BIOLOGY

Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes

(2012) L. Gui et al.   DEVELOPMENT

Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension

(2012) S. I. R. Lane et al.   DEVELOPMENT

Linking abnormal mitosis to the acquisition of DNA damage

(2012) Neil J. Ganem et al.   JOURNAL OF CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Human aneuploidy: mechanisms and new insights into an age-old problem

(2012) So I. Nagaoka et al.   NATURE REVIEWS GENETICS

Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension

(2012) A. Kolano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Dependent Susceptibility of Chromosome Cohesion to Premature Separase Activation in Mouse Oocytes1

(2011) Teresa Chiang et al.   BIOLOGY OF REPRODUCTION

Effect of Aging on Superovulation Efficiency, Aneuploidy Rates, and Sister Chromatid Cohesion in Mice Aged Up to 15 Months1

(2011) Julie A. Merriman et al.   BIOLOGY OF REPRODUCTION

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors

(2011) S. L. Thompson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes

(2010) Teresa Chiang et al.   CURRENT BIOLOGY

Age-Related Meiotic Segregation Errors in Mammalian Oocytes Are Preceded by Depletion of Cohesin and Sgo2

(2010) Lisa Martine Lister et al.   CURRENT BIOLOGY

Dual mechanism controls asymmetric spindle position in ascidian germ cell precursors

(2010) F. Prodon et al.   DEVELOPMENT

MCAK regulates chromosome alignment but is not necessary for preventing aneuploidy in mouse oocyte meiosis I

(2010) C. Illingworth et al.   DEVELOPMENT

MCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes

(2010) E. Vogt et al.   MOLECULAR HUMAN REPRODUCTION

Evidence That a Defective Spindle Assembly Checkpoint Is Not the Primary Cause of Maternal Age-Associated Aneuploidy in Mouse Eggs1

(2009) Francesca E. Duncan et al.   BIOLOGY OF REPRODUCTION

Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability

(2009) Samuel F. Bakhoum et al.   CURRENT BIOLOGY

A shift from kinesin 5-dependent metaphase spindle function during preimplantation development in mouse

(2009) G. FitzHarris   DEVELOPMENT

Age-associated increase in aneuploidy and changes in gene expression in mouse eggs

(2008) Hua Pan et al.   DEVELOPMENTAL BIOLOGY

Genome stability is ensured by temporal control of kinetochore–microtubule dynamics

(2008) Samuel F. Bakhoum et al.   NATURE CELL BIOLOGY