Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect

Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates

(2015) Christian S Ottolini et al.   NATURE GENETICS

Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes

(2015) Z. Holubcova et al.   SCIENCE

Bivalent separation into univalents precedes age-related meiosis I errors in oocytes

(2015) Yogo Sakakibara et al.   Nature Communications

Kinetochore microtubule establishment is defective in oocytes from aged mice

(2014) Maria Shomper et al.   CELL CYCLE

Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice

(2014) Yan YUN et al.   CELL CYCLE

The frequency of precocious segregation of sister chromatids in mouse female meiosis I is affected by genetic background

(2014) Anna Danylevska et al.   CHROMOSOME RESEARCH

Meikin is a conserved regulator of meiosis-I-specific kinetochore function

(2014) Jihye Kim et al.   NATURE

Age-Related Decrease of Meiotic Cohesins in Human Oocytes

(2014) Makiko Tsutsumi et al.   PLoS One

Single cell sequencing reveals low levels of aneuploidy across mammalian tissues

(2014) Kristin A. Knouse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meiotic recombination in mammals: localization and regulation

(2013) Frédéric Baudat et al.   NATURE REVIEWS GENETICS

Restarting life: fertilization and the transition from meiosis to mitosis

(2013) Dean Clift et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chromosome cohesion decreases in human eggs with advanced maternal age

(2012) Francesca E. Duncan et al.   AGING CELL

Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension

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Multiple meiotic errors caused by predivision of chromatids in women of advanced maternal age undergoing in vitro fertilisation

(2012) Alan H Handyside et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Human aneuploidy: mechanisms and new insights into an age-old problem

(2012) So I. Nagaoka et al.   NATURE REVIEWS GENETICS

Geometry and force behind kinetochore orientation: lessons from meiosis

(2012) Yoshinori Watanabe   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Age-Dependent Susceptibility of Chromosome Cohesion to Premature Separase Activation in Mouse Oocytes1

(2011) Teresa Chiang et al.   BIOLOGY OF REPRODUCTION

Complete Kinetochore Tracking Reveals Error-Prone Homologous Chromosome Biorientation in Mammalian Oocytes

(2011) Tomoya S. Kitajima et al.   CELL

Whole-Chromosome Aneuploidy Analysis in Human Oocytes: Focus on Comparative Genomic Hybridization

(2011) A. Obradors et al.   CYTOGENETIC AND GENOME RESEARCH

Aneuploidy in Human Spermatozoa

(2011) C. Templado et al.   CYTOGENETIC AND GENOME RESEARCH

The cytogenetics of polar bodies: insights into female meiosis and the diagnosis of aneuploidy

(2011) E. Fragouli et al.   MOLECULAR HUMAN REPRODUCTION

Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes

(2010) Teresa Chiang et al.   CURRENT BIOLOGY

Age-Related Meiotic Segregation Errors in Mammalian Oocytes Are Preceded by Depletion of Cohesin and Sgo2

(2010) Lisa Martine Lister et al.   CURRENT BIOLOGY

Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes

(2010) K. Tachibana-Konwalski et al.   GENES & DEVELOPMENT

Dynamics of cohesin proteins REC8, STAG3, SMC1  and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes

(2010) R. Garcia-Cruz et al.   HUMAN REPRODUCTION

Egg sharing for assisted conception: a window on oocyte quality

(2010) Malcolm Faddy et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Meiosis errors in over 20,000 oocytes studied in the practice of preimplantation aneuploidy testing

(2010) Anver Kuliev et al.   REPRODUCTIVE BIOMEDICINE ONLINE